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Best matches for Löhning M[au]:

IL-33 in T Cell Differentiation, Function, and Immune Homeostasis. Peine M et al. Trends Immunol. (2016)

The alarmin IL-33 promotes regulatory T-cell function in the intestine. Schiering C et al. Nature. (2014)

T<sub>H</sub>17 cells express ST2 and are controlled by the alarmin IL-33 in the small intestine. Pascual-Reguant A et al. Mucosal Immunol. (2017)

Search results

Items: 1 to 50 of 63

1.

Manipulation of the balance between Th2 and Th2/1 hybrid cells affects parasite nematode fitness in mice.

Affinass N, Zhang H, Löhning M, Hartmann S, Rausch S.

Eur J Immunol. 2018 Dec;48(12):1958-1964. doi: 10.1002/eji.201847639. Epub 2018 Oct 24.

PMID:
30267404
2.

Th2/1 Hybrid Cells Occurring in Murine and Human Strongyloidiasis Share Effector Functions of Th1 Cells.

Bock CN, Babu S, Breloer M, Rajamanickam A, Boothra Y, Brunn ML, Kühl AA, Merle R, Löhning M, Hartmann S, Rausch S.

Front Cell Infect Microbiol. 2017 Jun 20;7:261. doi: 10.3389/fcimb.2017.00261. eCollection 2017.

3.

Replicating viral vector platform exploits alarmin signals for potent CD8+ T cell-mediated tumour immunotherapy.

Kallert SM, Darbre S, Bonilla WV, Kreutzfeldt M, Page N, Müller P, Kreuzaler M, Lu M, Favre S, Kreppel F, Löhning M, Luther SA, Zippelius A, Merkler D, Pinschewer DD.

Nat Commun. 2017 May 26;8:15327. doi: 10.1038/ncomms15327.

4.

Synovial Fibroblasts Selectively Suppress Th1 Cell Responses through IDO1-Mediated Tryptophan Catabolism.

Tykocinski LO, Lauffer AM, Bohnen A, Kaul NC, Krienke S, Tretter T, Adam I, Mohapatra SR, Saikali P, Löhning M, Neidhart M, Gay S, Oezen I, Platten M, Opitz CA, Lorenz HM.

J Immunol. 2017 Apr 15;198(8):3109-3117. doi: 10.4049/jimmunol.1600600. Epub 2017 Mar 6.

5.

Spatiotemporally restricted arenavirus replication induces immune surveillance and type I interferon-dependent tumour regression.

Kalkavan H, Sharma P, Kasper S, Helfrich I, Pandyra AA, Gassa A, Virchow I, Flatz L, Brandenburg T, Namineni S, Heikenwalder M, Höchst B, Knolle PA, Wollmann G, von Laer D, Drexler I, Rathbun J, Cannon PM, Scheu S, Bauer J, Chauhan J, Häussinger D, Willimsky G, Löhning M, Schadendorf D, Brandau S, Schuler M, Lang PA, Lang KS.

Nat Commun. 2017 Mar 1;8:14447. doi: 10.1038/ncomms14447.

6.

TH17 cells express ST2 and are controlled by the alarmin IL-33 in the small intestine.

Pascual-Reguant A, Bayat Sarmadi J, Baumann C, Noster R, Cirera-Salinas D, Curato C, Pelczar P, Huber S, Zielinski CE, Löhning M, Hauser AE, Esplugues E.

Mucosal Immunol. 2017 Nov;10(6):1431-1442. doi: 10.1038/mi.2017.5. Epub 2017 Feb 15.

PMID:
28198366
7.

IL-33 Receptor-Expressing Regulatory T Cells Are Highly Activated, Th2 Biased and Suppress CD4 T Cell Proliferation through IL-10 and TGFβ Release.

Siede J, Fröhlich A, Datsi A, Hegazy AN, Varga DV, Holecska V, Saito H, Nakae S, Löhning M.

PLoS One. 2016 Aug 22;11(8):e0161507. doi: 10.1371/journal.pone.0161507. eCollection 2016.

8.

IL-33 in T Cell Differentiation, Function, and Immune Homeostasis.

Peine M, Marek RM, Löhning M.

Trends Immunol. 2016 May;37(5):321-333. doi: 10.1016/j.it.2016.03.007. Epub 2016 Apr 4. Review.

PMID:
27055914
9.

T-bet expression by Th cells promotes type 1 inflammation but is dispensable for colitis.

Zimmermann J, Kühl AA, Weber M, Grün JR, Löffler J, Haftmann C, Riedel R, Maschmeyer P, Lehmann K, Westendorf K, Mashreghi MF, Löhning M, Mack M, Radbruch A, Chang HD.

Mucosal Immunol. 2016 Nov;9(6):1487-1499. doi: 10.1038/mi.2016.5. Epub 2016 Feb 17.

PMID:
26883725
10.

B Cells Negatively Regulate the Establishment of CD49b(+)T-bet(+) Resting Memory T Helper Cells in the Bone Marrow.

Hojyo S, Sarkander J, Männe C, Mursell M, Hanazawa A, Zimmel D, Zhu J, Paul WE, Fillatreau S, Löhning M, Radbruch A, Tokoyoda K.

Front Immunol. 2016 Feb 2;7:26. doi: 10.3389/fimmu.2016.00026. eCollection 2016.

11.

Superoxide Dismutase 1 Protects Hepatocytes from Type I Interferon-Driven Oxidative Damage.

Bhattacharya A, Hegazy AN, Deigendesch N, Kosack L, Cupovic J, Kandasamy RK, Hildebrandt A, Merkler D, Kühl AA, Vilagos B, Schliehe C, Panse I, Khamina K, Baazim H, Arnold I, Flatz L, Xu HC, Lang PA, Aderem A, Takaoka A, Superti-Furga G, Colinge J, Ludewig B, Löhning M, Bergthaler A.

Immunity. 2015 Nov 17;43(5):974-86. doi: 10.1016/j.immuni.2015.10.013.

12.

Immunoactivation induced by chronic viral infection inhibits viral replication and drives immunosuppression through sustained IFN-I responses.

Honke N, Shaabani N, Merches K, Gassa A, Kraft A, Ehrhardt K, Häussinger D, Löhning M, Dittmer U, Hengel H, Recher M, Lang PA, Lang KS.

Eur J Immunol. 2016 Feb;46(2):372-80. doi: 10.1002/eji.201545765. Epub 2015 Nov 17.

13.

T-bet- and STAT4-dependent IL-33 receptor expression directly promotes antiviral Th1 cell responses.

Baumann C, Bonilla WV, Fröhlich A, Helmstetter C, Peine M, Hegazy AN, Pinschewer DD, Löhning M.

Proc Natl Acad Sci U S A. 2015 Mar 31;112(13):4056-61. doi: 10.1073/pnas.1418549112. Epub 2015 Mar 17.

14.

Deficiency of the B cell-activating factor receptor results in limited CD169+ macrophage function during viral infection.

Xu HC, Huang J, Khairnar V, Duhan V, Pandyra AA, Grusdat M, Shinde P, McIlwain DR, Maney SK, Gommerman J, Löhning M, Ohashi PS, Mak TW, Pieper K, Sic H, Speletas M, Eibel H, Ware CF, Tumanov AV, Kruglov AA, Nedospasov SA, Häussinger D, Recher M, Lang KS, Lang PA.

J Virol. 2015 May;89(9):4748-59. doi: 10.1128/JVI.02976-14. Epub 2015 Feb 11.

15.

Individual T helper cells have a quantitative cytokine memory.

Helmstetter C, Flossdorf M, Peine M, Kupz A, Zhu J, Hegazy AN, Duque-Correa MA, Zhang Q, Vainshtein Y, Radbruch A, Kaufmann SH, Paul WE, Höfer T, Löhning M.

Immunity. 2015 Jan 20;42(1):108-22. doi: 10.1016/j.immuni.2014.12.018. Epub 2014 Dec 25.

16.

miR-148a is upregulated by Twist1 and T-bet and promotes Th1-cell survival by regulating the proapoptotic gene Bim.

Haftmann C, Stittrich AB, Zimmermann J, Fang Z, Hradilkova K, Bardua M, Westendorf K, Heinz GA, Riedel R, Siede J, Lehmann K, Weinberger EE, Zimmel D, Lauer U, Häupl T, Sieper J, Backhaus M, Neumann C, Hoffmann U, Porstner M, Chen W, Grün JR, Baumgrass R, Matz M, Löhning M, Scheffold A, Wittmann J, Chang HD, Rajewsky N, Jäck HM, Radbruch A, Mashreghi MF.

Eur J Immunol. 2015 Apr;45(4):1192-205. doi: 10.1002/eji.201444633. Epub 2015 Jan 22.

17.

The alarmin IL-33 promotes regulatory T-cell function in the intestine.

Schiering C, Krausgruber T, Chomka A, Fröhlich A, Adelmann K, Wohlfert EA, Pott J, Griseri T, Bollrath J, Hegazy AN, Harrison OJ, Owens BMJ, Löhning M, Belkaid Y, Fallon PG, Powrie F.

Nature. 2014 Sep 25;513(7519):564-568. doi: 10.1038/nature13577. Epub 2014 Jul 16.

18.

Type I interferon protects antiviral CD8+ T cells from NK cell cytotoxicity.

Xu HC, Grusdat M, Pandyra AA, Polz R, Huang J, Sharma P, Deenen R, Köhrer K, Rahbar R, Diefenbach A, Gibbert K, Löhning M, Höcker L, Waibler Z, Häussinger D, Mak TW, Ohashi PS, Lang KS, Lang PA.

Immunity. 2014 Jun 19;40(6):949-60. doi: 10.1016/j.immuni.2014.05.004. Epub 2014 Jun 5.

19.

Usp18 driven enforced viral replication in dendritic cells contributes to break of immunological tolerance in autoimmune diabetes.

Honke N, Shaabani N, Zhang DE, Iliakis G, Xu HC, Häussinger D, Recher M, Löhning M, Lang PA, Lang KS.

PLoS Pathog. 2013 Oct;9(10):e1003650. doi: 10.1371/journal.ppat.1003650. Epub 2013 Oct 24.

20.

Stable T-bet(+)GATA-3(+) Th1/Th2 hybrid cells arise in vivo, can develop directly from naive precursors, and limit immunopathologic inflammation.

Peine M, Rausch S, Helmstetter C, Fröhlich A, Hegazy AN, Kühl AA, Grevelding CG, Höfer T, Hartmann S, Löhning M.

PLoS Biol. 2013;11(8):e1001633. doi: 10.1371/journal.pbio.1001633. Epub 2013 Aug 20.

21.

CD49b-dependent establishment of T helper cell memory.

Hanazawa A, Hayashizaki K, Shinoda K, Yagita H, Okumura K, Löhning M, Hara T, Tani-ichi S, Ikuta K, Eckes B, Radbruch A, Tokoyoda K, Nakayama T.

Immunol Cell Biol. 2013 Sep;91(8):524-31. doi: 10.1038/icb.2013.36. Epub 2013 Jul 30.

PMID:
23897120
22.

CD49b/CD69-Dependent Generation of Resting T Helper Cell Memory.

Hanazawa A, Löhning M, Radbruch A, Tokoyoda K.

Front Immunol. 2013 Jul 10;4:183. doi: 10.3389/fimmu.2013.00183. eCollection 2013.

23.

Unlike αβ T cells, γδ T cells, LTi cells and NKT cells do not require IRF4 for the production of IL-17A and IL-22.

Raifer H, Mahiny AJ, Bollig N, Petermann F, Hellhund A, Kellner K, Guralnik A, Reinhard K, Bothur E, Huber M, Bauer S, Löhning M, Kiss EA, Ganal SC, Diefenbach A, Korn T, Lohoff M.

Eur J Immunol. 2012 Dec;42(12):3189-201. doi: 10.1002/eji.201142155. Epub 2012 Oct 17.

24.

Human monocytes and macrophages differ in their mechanisms of adaptation to hypoxia.

Fangradt M, Hahne M, Gaber T, Strehl C, Rauch R, Hoff P, Löhning M, Burmester GR, Buttgereit F.

Arthritis Res Ther. 2012 Aug 7;14(4):R181. doi: 10.1186/ar4011.

25.

Tolerance induction with T cell-dependent protein antigens induces regulatory sialylated IgGs.

Oefner CM, Winkler A, Hess C, Lorenz AK, Holecska V, Huxdorf M, Schommartz T, Petzold D, Bitterling J, Schoen AL, Stoehr AD, Vu Van D, Darcan-Nikolaisen Y, Blanchard V, Schmudde I, Laumonnier Y, Ströver HA, Hegazy AN, Eiglmeier S, Schoen CT, Mertes MM, Loddenkemper C, Löhning M, König P, Petersen A, Luger EO, Collin M, Köhl J, Hutloff A, Hamelmann E, Berger M, Wardemann H, Ehlers M.

J Allergy Clin Immunol. 2012 Jun;129(6):1647-55.e13. doi: 10.1016/j.jaci.2012.02.037. Epub 2012 Apr 12.

PMID:
22502800
26.

The alarmin interleukin-33 drives protective antiviral CD8⁺ T cell responses.

Bonilla WV, Fröhlich A, Senn K, Kallert S, Fernandez M, Johnson S, Kreutzfeldt M, Hegazy AN, Schrick C, Fallon PG, Klemenz R, Nakae S, Adler H, Merkler D, Löhning M, Pinschewer DD.

Science. 2012 Feb 24;335(6071):984-9. doi: 10.1126/science.1215418. Epub 2012 Feb 9.

27.

Enforced viral replication activates adaptive immunity and is essential for the control of a cytopathic virus.

Honke N, Shaabani N, Cadeddu G, Sorg UR, Zhang DE, Trilling M, Klingel K, Sauter M, Kandolf R, Gailus N, van Rooijen N, Burkart C, Baldus SE, Grusdat M, Löhning M, Hengel H, Pfeffer K, Tanaka M, Häussinger D, Recher M, Lang PA, Lang KS.

Nat Immunol. 2011 Nov 20;13(1):51-7. doi: 10.1038/ni.2169.

PMID:
22101728
28.

Eosinophils are required for the maintenance of plasma cells in the bone marrow.

Chu VT, Fröhlich A, Steinhauser G, Scheel T, Roch T, Fillatreau S, Lee JJ, Löhning M, Berek C.

Nat Immunol. 2011 Feb;12(2):151-9. doi: 10.1038/ni.1981. Epub 2011 Jan 9.

PMID:
21217761
29.

Macrophage migration inhibitory factor counterregulates dexamethasone-mediated suppression of hypoxia-inducible factor-1 alpha function and differentially influences human CD4+ T cell proliferation under hypoxia.

Gaber T, Schellmann S, Erekul KB, Fangradt M, Tykwinska K, Hahne M, Maschmeyer P, Wagegg M, Stahn C, Kolar P, Dziurla R, Löhning M, Burmester GR, Buttgereit F.

J Immunol. 2011 Jan 15;186(2):764-74. doi: 10.4049/jimmunol.0903421. Epub 2010 Dec 17.

30.

Viral replicative capacity is the primary determinant of lymphocytic choriomeningitis virus persistence and immunosuppression.

Bergthaler A, Flatz L, Hegazy AN, Johnson S, Horvath E, Löhning M, Pinschewer DD.

Proc Natl Acad Sci U S A. 2010 Dec 14;107(50):21641-6. doi: 10.1073/pnas.1011998107. Epub 2010 Nov 22.

31.

The microRNA miR-182 is induced by IL-2 and promotes clonal expansion of activated helper T lymphocytes.

Stittrich AB, Haftmann C, Sgouroudis E, Kühl AA, Hegazy AN, Panse I, Riedel R, Flossdorf M, Dong J, Fuhrmann F, Heinz GA, Fang Z, Li N, Bissels U, Hatam F, Jahn A, Hammoud B, Matz M, Schulze FM, Baumgrass R, Bosio A, Mollenkopf HJ, Grün J, Thiel A, Chen W, Höfer T, Loddenkemper C, Löhning M, Chang HD, Rajewsky N, Radbruch A, Mashreghi MF.

Nat Immunol. 2010 Nov;11(11):1057-62. doi: 10.1038/ni.1945. Epub 2010 Oct 10.

PMID:
20935646
32.

Short-term memory in gene induction reveals the regulatory principle behind stochastic IL-4 expression.

Mariani L, Schulz EG, Lexberg MH, Helmstetter C, Radbruch A, Löhning M, Höfer T.

Mol Syst Biol. 2010 Apr 13;6:359. doi: 10.1038/msb.2010.13.

33.

T cells can mediate viral clearance from ependyma but not from brain parenchyma in a major histocompatibility class I- and perforin-independent manner.

Pinschewer DD, Schedensack M, Bergthaler A, Horvath E, Brück W, Löhning M, Merkler D.

Brain. 2010 Apr;133(Pt 4):1054-66. doi: 10.1093/brain/awq028. Epub 2010 Mar 30.

34.

Development of replication-defective lymphocytic choriomeningitis virus vectors for the induction of potent CD8+ T cell immunity.

Flatz L, Hegazy AN, Bergthaler A, Verschoor A, Claus C, Fernandez M, Gattinoni L, Johnson S, Kreppel F, Kochanek S, Broek Mv, Radbruch A, Lévy F, Lambert PH, Siegrist CA, Restifo NP, Löhning M, Ochsenbein AF, Nabel GJ, Pinschewer DD.

Nat Med. 2010 Mar;16(3):339-45. doi: 10.1038/nm.2104. Epub 2010 Feb 7.

35.

Interferons direct Th2 cell reprogramming to generate a stable GATA-3(+)T-bet(+) cell subset with combined Th2 and Th1 cell functions.

Hegazy AN, Peine M, Helmstetter C, Panse I, Fröhlich A, Bergthaler A, Flatz L, Pinschewer DD, Radbruch A, Löhning M.

Immunity. 2010 Jan 29;32(1):116-28. doi: 10.1016/j.immuni.2009.12.004. Epub 2010 Jan 14.

36.

Professional memory CD4+ T lymphocytes preferentially reside and rest in the bone marrow.

Tokoyoda K, Zehentmeier S, Hegazy AN, Albrecht I, Grün JR, Löhning M, Radbruch A.

Immunity. 2009 May;30(5):721-30. doi: 10.1016/j.immuni.2009.03.015. Epub 2009 May 7.

37.

Autoregulation of Th1-mediated inflammation by twist1.

Niesner U, Albrecht I, Janke M, Doebis C, Loddenkemper C, Lexberg MH, Eulenburg K, Kreher S, Koeck J, Baumgrass R, Bonhagen K, Kamradt T, Enghard P, Humrich JY, Rutz S, Schulze-Topphoff U, Aktas O, Bartfeld S, Radbruch H, Hegazy AN, Löhning M, Baumgart DC, Duchmann R, Rudwaleit M, Häupl T, Gitelman I, Krenn V, Gruen J, Sieper J, Zeitz M, Wiedenmann B, Zipp F, Hamann A, Janitz M, Scheffold A, Burmester GR, Chang HD, Radbruch A.

J Exp Med. 2008 Aug 4;205(8):1889-901. doi: 10.1084/jem.20072468. Epub 2008 Jul 28.

38.

Aggravation of viral hepatitis by platelet-derived serotonin.

Lang PA, Contaldo C, Georgiev P, El-Badry AM, Recher M, Kurrer M, Cervantes-Barragan L, Ludewig B, Calzascia T, Bolinger B, Merkler D, Odermatt B, Bader M, Graf R, Clavien PA, Hegazy AN, Löhning M, Harris NL, Ohashi PS, Hengartner H, Zinkernagel RM, Lang KS.

Nat Med. 2008 Jul;14(7):756-61. doi: 10.1038/nm1780. Epub 2008 May 30.

PMID:
18516052
39.

Detection and isolation of cytokine secreting cells using the cytometric cytokine secretion assay.

Assenmacher M, Löhning M, Radbruch A.

Curr Protoc Immunol. 2002 Feb;Chapter 6:Unit 6.27. doi: 10.1002/0471142735.im0627s46.

PMID:
18432889
40.

Long-lived virus-reactive memory T cells generated from purified cytokine-secreting T helper type 1 and type 2 effectors.

Löhning M, Hegazy AN, Pinschewer DD, Busse D, Lang KS, Höfer T, Radbruch A, Zinkernagel RM, Hengartner H.

J Exp Med. 2008 Jan 21;205(1):53-61. doi: 10.1084/jem.20071855. Epub 2008 Jan 14.

41.

"Negative vaccination" by specific CD4 T cell tolerisation enhances virus-specific protective antibody responses.

Lang KS, Hegazy AN, Lang PA, Eschli B, Löhning M, Hengartner H, Zinkernagel RM, Recher M.

PLoS One. 2007 Nov 14;2(11):e1162.

42.

A critical control element for interleukin-4 memory expression in T helper lymphocytes.

Tykocinski LO, Hajkova P, Chang HD, Stamm T, Sözeri O, Löhning M, Hu-Li J, Niesner U, Kreher S, Friedrich B, Pannetier C, Grütz G, Walter J, Paul WE, Radbruch A.

J Biol Chem. 2005 Aug 5;280(31):28177-85. Epub 2005 Jun 7.

43.

Inverse correlation between IL-7 receptor expression and CD8 T cell exhaustion during persistent antigen stimulation.

Lang KS, Recher M, Navarini AA, Harris NL, Löhning M, Junt T, Probst HC, Hengartner H, Zinkernagel RM.

Eur J Immunol. 2005 Mar;35(3):738-45.

44.

Inducible costimulator-positive T cells are required for allergen-induced local B-cell infiltration and antigen-specific IgE production in lung tissue.

Beier KC, Hutloff A, Löhning M, Kallinich T, Kroczek RA, Hamelmann E.

J Allergy Clin Immunol. 2004 Oct;114(4):775-82.

PMID:
15480315
45.

Transcriptional control networks of cell differentiation: insights from helper T lymphocytes.

Mariani L, Löhning M, Radbruch A, Höfer T.

Prog Biophys Mol Biol. 2004 Sep;86(1):45-76.

PMID:
15261525
46.

Establishment of memory for IL-10 expression in developing T helper 2 cells requires repetitive IL-4 costimulation and does not impair proliferation.

Löhning M, Richter A, Stamm T, Hu-Li J, Assenmacher M, Paul WE, Radbruch A.

Proc Natl Acad Sci U S A. 2003 Oct 14;100(21):12307-12. Epub 2003 Sep 26.

47.

Expression of ICOS in vivo defines CD4+ effector T cells with high inflammatory potential and a strong bias for secretion of interleukin 10.

Löhning M, Hutloff A, Kallinich T, Mages HW, Bonhagen K, Radbruch A, Hamelmann E, Kroczek RA.

J Exp Med. 2003 Jan 20;197(2):181-93.

48.

Endotoxins prevent murine IgE production, T(H)2 immune responses, and development of airway eosinophilia but not airway hyperreactivity.

Gerhold K, Blümchen K, Bock A, Seib C, Stock P, Kallinich T, Löhning M, Wahn U, Hamelmann E.

J Allergy Clin Immunol. 2002 Jul;110(1):110-6.

PMID:
12110829
49.

GATA-3 transcriptional imprinting in Th2 lymphocytes: a mathematical model.

Höfer T, Nathansen H, Löhning M, Radbruch A, Heinrich R.

Proc Natl Acad Sci U S A. 2002 Jul 9;99(14):9364-8. Epub 2002 Jun 26.

50.

Cytokine memory of T helper lymphocytes.

Löhning M, Richter A, Radbruch A.

Adv Immunol. 2002;80:115-81. Review.

PMID:
12078480

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