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Items: 1 to 50 of 165

1.

Proline-based hydroxamates targeting the zinc-dependent deacetylase LpxC: Synthesis, antibacterial properties, and docking studies.

Kalinin DV, Agoglitta O, Van de Vyver H, Melesina J, Wagner S, Riemann B, Schäfers M, Sippl W, Löffler B, Holl R.

Bioorg Med Chem. 2019 May 15;27(10):1997-2018. doi: 10.1016/j.bmc.2019.03.056. Epub 2019 Mar 30.

PMID:
30954331
2.

Clinical S. aureus Isolates Vary in Their Virulence to Promote Adaptation to the Host.

Tuchscherr L, Pöllath C, Siegmund A, Deinhardt-Emmer S, Hoerr V, Svensson CM, Thilo Figge M, Monecke S, Löffler B.

Toxins (Basel). 2019 Mar 1;11(3). pii: E135. doi: 10.3390/toxins11030135.

3.

Author Correction: Per2 induction limits lymphoid-biased haematopoietic stem cells and lymphopoiesis in the context of DNA damage and ageing.

Wang J, Morita Y, Han B, Niemann S, Löffler B, Rudolph KL.

Nat Cell Biol. 2019 Jun;21(6):791-792. doi: 10.1038/s41556-019-0279-4.

PMID:
30808996
4.

Use of MALDI-TOF mass spectrometry to detect nosocomial outbreaks of Serratia marcescens and Citrobacter freundii.

Rödel J, Mellmann A, Stein C, Alexi M, Kipp F, Edel B, Dawczynski K, Brandt C, Seidel L, Pfister W, Löffler B, Straube E.

Eur J Clin Microbiol Infect Dis. 2019 Mar;38(3):581-591. doi: 10.1007/s10096-018-03462-2. Epub 2019 Jan 24.

PMID:
30680577
5.

Rapid antibiotic susceptibility testing in blood culture diagnostics performed by direct inoculation using the VITEK®-2 and BD Phoenix™ platforms.

Höring S, Massarani AS, Löffler B, Rödel J.

Eur J Clin Microbiol Infect Dis. 2019 Mar;38(3):471-478. doi: 10.1007/s10096-018-03445-3. Epub 2019 Jan 24.

PMID:
30680555
7.

Counteracting the Slowdown of Reaction Times in a Vigilance Experiment With 40-Hz Transcranial Alternating Current Stimulation.

Loffler BS, Stecher HI, Fudickar S, de Sordi D, Otto-Sobotka F, Hein A, Herrmann CS.

IEEE Trans Neural Syst Rehabil Eng. 2018 Oct;26(10):2053-2061. doi: 10.1109/TNSRE.2018.2869471. Epub 2018 Sep 10.

PMID:
30207962
8.

Complement 5a Receptor Polymorphisms Are Associated With Panton-Valentine Leukocidin-positive Staphylococcus aureus Colonization in African Pygmies.

Schaumburg F, Witten A, Flamen A, Stoll M, Alabi AS, Kremsner PG, Löffler B, Zipfel PF, Velavan TP, Peters G.

Clin Infect Dis. 2019 Feb 15;68(5):854-856. doi: 10.1093/cid/ciy666.

PMID:
30192927
9.

Deterioration of Organ Function As a Hallmark in Sepsis: The Cellular Perspective.

Bauer M, Coldewey SM, Leitner M, Löffler B, Weis S, Wetzker R.

Front Immunol. 2018 Jun 26;9:1460. doi: 10.3389/fimmu.2018.01460. eCollection 2018.

10.
11.

Staphylococcus aureus requires less virulence to establish an infection in diabetic hosts.

Tuchscherr L, Korpos È, van de Vyver H, Findeisen C, Kherkheulidze S, Siegmund A, Deinhardt-Emmer S, Bach O, Rindert M, Mellmann A, Sunderkötter C, Peters G, Sorokin L, Löffler B.

Int J Med Microbiol. 2018 Oct;308(7):761-769. doi: 10.1016/j.ijmm.2018.05.004. Epub 2018 May 22.

PMID:
29843979
12.

Author Correction: The Staphylococcus aureus extracellular matrix protein (Emp) has a fibrous structure and binds to different extracellular matrices.

Geraci J, Neubauer S, Pöllath C, Hansen U, Rizzo F, Krafft C, Westermann M, Hussain M, Peters G, Pletz MW, Löffler B, Makarewicz O, Tuchscherr L.

Sci Rep. 2018 May 25;8(1):8396. doi: 10.1038/s41598-018-26315-6.

13.

Early adjustment of antimicrobial therapy after PCR/electrospray ionization mass spectrometry-based pathogen detection in critically ill patients with suspected sepsis.

Karrasch M, Geraci J, Sachse S, Rödel J, Löffler B, Bauer M, Thomas-Rüddel D, Hagel S, Aschenbach R, Bloos F.

Clin Chem Lab Med. 2018 Jul 26;56(8):e207-e209. doi: 10.1515/cclm-2017-1110. No abstract available.

PMID:
29626413
14.

S. aureus endocarditis: Clinical aspects and experimental approaches.

Hoerr V, Franz M, Pletz MW, Diab M, Niemann S, Faber C, Doenst T, Schulze PC, Deinhardt-Emmer S, Löffler B.

Int J Med Microbiol. 2018 Aug;308(6):640-652. doi: 10.1016/j.ijmm.2018.02.004. Epub 2018 Feb 21. Review.

PMID:
29526448
15.

Staphylococcus aureus triggers a shift from influenza virus-induced apoptosis to necrotic cell death.

van Krüchten A, Wilden JJ, Niemann S, Peters G, Löffler B, Ludwig S, Ehrhardt C.

FASEB J. 2018 May;32(5):2779-2793. doi: 10.1096/fj.201701006R. Epub 2018 Jan 11.

PMID:
29401589
16.

Complement involvement in bone homeostasis and bone disorders.

Mödinger Y, Löffler B, Huber-Lang M, Ignatius A.

Semin Immunol. 2018 Jun;37:53-65. doi: 10.1016/j.smim.2018.01.001. Epub 2018 Feb 1. Review.

17.

Panton-Valentine Leukocidin associated with S. aureus osteomyelitis activates platelets via neutrophil secretion products.

Niemann S, Bertling A, Brodde MF, Fender AC, Van de Vyver H, Hussain M, Holzinger D, Reinhardt D, Peters G, Heilmann C, Löffler B, Kehrel BE.

Sci Rep. 2018 Feb 1;8(1):2185. doi: 10.1038/s41598-018-20582-z.

18.

First Time Isolation of Mycobacterium hassiacum From a Respiratory Sample.

Deinhardt-Emmer S, Höring S, Mura C, Hillemann D, Hermann B, Sachse S, Bohnert J, Löffler B.

Clin Med Insights Circ Respir Pulm Med. 2018 Jan 3;12:1179548417747529. doi: 10.1177/1179548417747529. eCollection 2018.

19.

Virulence patterns of Staphylococcus aureus strains from nasopharyngeal colonization.

Deinhardt-Emmer S, Sachse S, Geraci J, Fischer C, Kwetkat A, Dawczynski K, Tuchscherr L, Löffler B.

J Hosp Infect. 2018 Nov;100(3):309-315. doi: 10.1016/j.jhin.2017.12.011. Epub 2017 Dec 15.

PMID:
29253623
20.

The Staphylococcus aureus extracellular matrix protein (Emp) has a fibrous structure and binds to different extracellular matrices.

Geraci J, Neubauer S, Pöllath C, Hansen U, Rizzo F, Krafft C, Westermann M, Hussain M, Peters G, Pletz MW, Löffler B, Makarewicz O, Tuchscherr L.

Sci Rep. 2017 Oct 20;7(1):13665. doi: 10.1038/s41598-017-14168-4. Erratum in: Sci Rep. 2018 May 25;8(1):8396.

21.

Acute diarrhoea due to a Shiga toxin 2e-producing Escherichia coli O8 : H19.

Saupe A, Edel B, Pfister W, Löffler B, Ehricht R, Rödel J.

JMM Case Rep. 2017 Jun 14;4(6):e005099. doi: 10.1099/jmmcr.0.005099. eCollection 2017 Jun.

22.

Optimized efflux assay for the NorA multidrug efflux pump in Staphylococcus aureus.

Zimmermann S, Tuchscherr L, Rödel J, Löffler B, Bohnert JA.

J Microbiol Methods. 2017 Nov;142:39-40. doi: 10.1016/j.mimet.2017.09.001. Epub 2017 Sep 5.

PMID:
28887002
23.

Staphylococcus aureus Regulator Sigma B is Important to Develop Chronic Infections in Hematogenous Murine Osteomyelitis Model.

Tuchscherr L, Geraci J, Löffler B.

Pathogens. 2017 Jul 15;6(3). pii: E31. doi: 10.3390/pathogens6030031.

24.

GlucoCEST magnetic resonance imaging in vivo may be diagnostic of acute renal allograft rejection.

Kentrup D, Bovenkamp P, Busch A, Schuette-Nuetgen K, Pawelski H, Pavenstädt H, Schlatter E, Herrmann KH, Reichenbach JR, Löffler B, Heitplatz B, Van Marck V, Yadav NN, Liu G, van Zijl PCM, Reuter S, Hoerr V.

Kidney Int. 2017 Sep;92(3):757-764. doi: 10.1016/j.kint.2017.04.015. Epub 2017 Jul 12.

PMID:
28709641
25.

Vascular graft infection: a new model for treatment management?

Deinhardt-Emmer S, Hoerr V, Löffler B.

Future Microbiol. 2017 Jun;12:651-654. doi: 10.2217/fmb-2017-0068. Epub 2017 May 25. No abstract available.

PMID:
28541093
26.

Study on the utility of a statewide counselling programme for improving mortality outcomes of patients with Staphylococcus aureus bacteraemia in Thuringia (SUPPORT): a study protocol of a cluster-randomised crossover trial.

Weis S, Hagel S, Schmitz RP, Scherag A, Brunkhorst FM, Forstner C, Löffler B, Pletz MW.

BMJ Open. 2017 Apr 8;7(4):e013976. doi: 10.1136/bmjopen-2016-013976.

27.

Cardiac 4D phase-contrast CMR at 9.4 T using self-gated ultra-short echo time (UTE) imaging.

Krämer M, Motaal AG, Herrmann KH, Löffler B, Reichenbach JR, Strijkers GJ, Hoerr V.

J Cardiovasc Magn Reson. 2017 Mar 31;19(1):39. doi: 10.1186/s12968-017-0351-9.

28.

Mitogen-activated protein kinases (MAPKs) regulate IL-6 over-production during concomitant influenza virus and Staphylococcus aureus infection.

Klemm C, Bruchhagen C, van Krüchten A, Niemann S, Löffler B, Peters G, Ludwig S, Ehrhardt C.

Sci Rep. 2017 Feb 14;7:42473. doi: 10.1038/srep42473.

29.

Correction: Risk Factors for Multi-Drug Resistant Pathogens and Failure of Empiric First-Line Therapy in Acute Cholangitis.

Reuken PA, Torres D, Baier M, Löffler B, Lübbert C, Lippmann N, Stallmach A, Bruns T.

PLoS One. 2017 Feb 13;12(2):e0172373. doi: 10.1371/journal.pone.0172373. eCollection 2017.

30.

A Novel Mouse Model of Staphylococcus aureus Vascular Graft Infection: Noninvasive Imaging of Biofilm Development in Vivo.

Van de Vyver H, Bovenkamp PR, Hoerr V, Schwegmann K, Tuchscherr L, Niemann S, Kursawe L, Grosse C, Moter A, Hansen U, Neugebauer U, Kuhlmann MT, Peters G, Hermann S, Löffler B.

Am J Pathol. 2017 Feb;187(2):268-279. doi: 10.1016/j.ajpath.2016.10.005. Epub 2017 Jan 11.

PMID:
28088288
31.

Risk Factors for Multi-Drug Resistant Pathogens and Failure of Empiric First-Line Therapy in Acute Cholangitis.

Reuken PA, Torres D, Baier M, Löffler B, Lübbert C, Lippmann N, Stallmach A, Bruns T.

PLoS One. 2017 Jan 11;12(1):e0169900. doi: 10.1371/journal.pone.0169900. eCollection 2017. Erratum in: PLoS One. 2017 Feb 13;12 (2):e0172373.

32.

Evaluation of loop-mediated isothermal amplification for the rapid identification of bacteria and resistance determinants in positive blood cultures.

Rödel J, Bohnert JA, Stoll S, Wassill L, Edel B, Karrasch M, Löffler B, Pfister W.

Eur J Clin Microbiol Infect Dis. 2017 Jun;36(6):1033-1040. doi: 10.1007/s10096-016-2888-1. Epub 2017 Jan 6.

PMID:
28063000
33.

Post-invasion events after infection with Staphylococcus aureus are strongly dependent on both the host cell type and the infecting S. aureus strain.

Strobel M, Pförtner H, Tuchscherr L, Völker U, Schmidt F, Kramko N, Schnittler HJ, Fraunholz MJ, Löffler B, Peters G, Niemann S.

Clin Microbiol Infect. 2016 Sep;22(9):799-809. doi: 10.1016/j.cmi.2016.06.020. Epub 2016 Jul 5.

34.

Characteristics and management of patients with influenza in a German hospital during the 2014/2015 influenza season.

Hagel S, Ludewig K, Moeser A, Baier M, Löffler B, Schleenvoigt B, Forstner C, Pletz MW.

Infection. 2016 Oct;44(5):667-72. doi: 10.1007/s15010-016-0920-0. Epub 2016 Jul 5.

PMID:
27380386
35.

Staphylococcus aureus-Associated Musculoskeletal Infections.

Idelevich EA, Kreis C, Löffler B, Peters G.

Curr Top Microbiol Immunol. 2017;409:229-261. doi: 10.1007/82_2016_19.

PMID:
27380269
36.

Corrigendum: Labeling and Selective Inactivation of Gram-Positive Bacteria Employing Bimodal Photoprobes with Dual Readouts.

Galstyan A, Block D, Niemann S, Grüner MC, Abbruzzetti S, Oneto M, Daniliuc CG, Hermann S, Viappiani C, Schäfers M, Löffler B, Strassert CA, Faust A.

Chemistry. 2016 Jun 27;22(27):9051. doi: 10.1002/chem.201601576. Epub 2016 Jun 1. No abstract available.

PMID:
27334237
37.

[Treatment of penicillin-sensitive staphylococcus aureus - in reply].

Weis S, Kaasch AJ, Rieg S, Löffler B, Hagel S, Forstner C, Brunkhorst FM, Pletz MW.

Dtsch Med Wochenschr. 2016 May;141(10):675. doi: 10.1055/s-0041-108937. Epub 2016 May 13. German. No abstract available.

PMID:
27176056
38.

[Which antibiotic to choose? - in reply].

Weis S, Kaasch AJ, Rieg S, Löffler B, Hagel S, Forstner C, Brunkhorst FM, Pletz MW.

Dtsch Med Wochenschr. 2016 May;141(10):675-6. doi: 10.1055/s-0041-108934. Epub 2016 May 13. German. No abstract available.

PMID:
27176055
39.

Characterization and prediction of the mechanism of action of antibiotics through NMR metabolomics.

Hoerr V, Duggan GE, Zbytnuik L, Poon KK, Große C, Neugebauer U, Methling K, Löffler B, Vogel HJ.

BMC Microbiol. 2016 May 10;16:82. doi: 10.1186/s12866-016-0696-5.

40.

Per2 induction limits lymphoid-biased haematopoietic stem cells and lymphopoiesis in the context of DNA damage and ageing.

Wang J, Morita Y, Han B, Niemann S, Löffler B, Rudolph KL.

Nat Cell Biol. 2016 May;18(5):480-90. doi: 10.1038/ncb3342. Epub 2016 Apr 18. Erratum in: Nat Cell Biol. 2019 Jun;21(6):791-792.

PMID:
27088856
41.

Clinical Significance and Pathogenesis of Staphylococcal Small Colony Variants in Persistent Infections.

Kahl BC, Becker K, Löffler B.

Clin Microbiol Rev. 2016 Apr;29(2):401-27. doi: 10.1128/CMR.00069-15. Review.

42.

Dietary restriction improves repopulation but impairs lymphoid differentiation capacity of hematopoietic stem cells in early aging.

Tang D, Tao S, Chen Z, Koliesnik IO, Calmes PG, Hoerr V, Han B, Gebert N, Zörnig M, Löffler B, Morita Y, Rudolph KL.

J Exp Med. 2016 Apr 4;213(4):535-53. doi: 10.1084/jem.20151100. Epub 2016 Mar 7.

43.

Labeling and Selective Inactivation of Gram-Positive Bacteria Employing Bimodal Photoprobes with Dual Readouts.

Galstyan A, Block D, Niemann S, Grüner MC, Abbruzzetti S, Oneto M, Daniliuc CG, Hermann S, Viappiani C, Schäfers M, Löffler B, Strassert CA, Faust A.

Chemistry. 2016 Apr 4;22(15):5243-52. doi: 10.1002/chem.201504935. Epub 2016 Mar 1. Erratum in: Chemistry. 2016 Jun 27;22(27):9051.

PMID:
26929124
44.

Should daptomycin-rifampin combinations for MSSA/MRSA isolates be avoided because of antagonism?

Stein C, Makarewicz O, Forstner C, Weis S, Hagel S, Löffler B, Pletz MW.

Infection. 2016 Aug;44(4):499-504. doi: 10.1007/s15010-016-0874-2. Epub 2016 Jan 21.

PMID:
26797915
45.

Antibiotic treatment algorithm development based on a microarray nucleic acid assay for rapid bacterial identification and resistance determination from positive blood cultures.

Rödel J, Karrasch M, Edel B, Stoll S, Bohnert J, Löffler B, Saupe A, Pfister W.

Diagn Microbiol Infect Dis. 2016 Mar;84(3):252-7. doi: 10.1016/j.diagmicrobio.2015.10.021. Epub 2015 Nov 14.

PMID:
26712265
46.

Zwitterionic Cellulose Carbamate with Regioselective Substitution Pattern: A Coating Material Possessing Antimicrobial Activity.

Elschner T, Lüdecke C, Kalden D, Roth M, Löffler B, Jandt KD, Heinze T.

Macromol Biosci. 2016 Apr;16(4):522-34. doi: 10.1002/mabi.201500349. Epub 2015 Dec 3.

PMID:
26632022
47.

Staphylococcus aureus develops increased resistance to antibiotics by forming dynamic small colony variants during chronic osteomyelitis.

Tuchscherr L, Kreis CA, Hoerr V, Flint L, Hachmeister M, Geraci J, Bremer-Streck S, Kiehntopf M, Medina E, Kribus M, Raschke M, Pletz M, Peters G, Löffler B.

J Antimicrob Chemother. 2016 Feb;71(2):438-48. doi: 10.1093/jac/dkv371. Epub 2015 Nov 20.

PMID:
26589581
48.

Selective Inactivation of Resistant Gram-Positive Pathogens with a Light-Driven Hybrid Nanomaterial.

Grüner M, Tuchscherr L, Löffler B, Gonnissen D, Riehemann K, Staniford MC, Kynast U, Strassert CA.

ACS Appl Mater Interfaces. 2015 Sep 23;7(37):20965-71. doi: 10.1021/acsami.5b06742. Epub 2015 Sep 11.

PMID:
26360157
49.

Staphylococcus aureus dynamically adapts global regulators and virulence factor expression in the course from acute to chronic infection.

Tuchscherr L, Löffler B.

Curr Genet. 2016 Feb;62(1):15-7. doi: 10.1007/s00294-015-0503-0. Epub 2015 Jun 30. Review.

PMID:
26123224
50.

[Staphylococcus aureus bacteremia - a distinct entity].

Weis S, Kaasch AJ, Rieg S, Löffler B, Hagel S, Forstner C, Brunkhorst FM, Pletz MW.

Dtsch Med Wochenschr. 2015 Jun;140(13):982-9. doi: 10.1055/s-0041-102453. Epub 2015 Jun 26. Review. German.

PMID:
26115133

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