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Items: 36


Quorum and Light Signals Modulate Acetoin/Butanediol Catabolism in Acinetobacter spp.

Tuttobene MR, Fernández-García L, Blasco L, Cribb P, Ambroa A, Müller GL, Fernández-Cuenca F, Bleriot I, Rodríguez RE, Barbosa BGV, Lopez-Rojas R, Trastoy R, López M, Bou G, Tomás M, Mussi MA.

Front Microbiol. 2019 Jun 20;10:1376. doi: 10.3389/fmicb.2019.01376. eCollection 2019.


First identification of blaNDM-1 carbapenemase in blaOXA-94-producing Acinetobacter baumannii ST85 in Spain.

Fernández-Cuenca F, Pérez-Palacios P, Galán-Sánchez F, López-Cerero L, López-Hernández I, López Rojas R, Arca-Suárez J, Díaz-de Alba P, Rodríguez Iglesias M, Pascual A.

Enferm Infecc Microbiol Clin. 2019 May 4. pii: S0213-005X(19)30156-9. doi: 10.1016/j.eimc.2019.03.008. [Epub ahead of print] English, Spanish.


Comparative activity of a polyhexanide-betaine solution against biofilms produced by multidrug-resistant bacteria belonging to high-risk clones.

Machuca J, Lopez-Rojas R, Fernandez-Cuenca F, Pascual Á.

J Hosp Infect. 2019 Sep;103(1):e92-e96. doi: 10.1016/j.jhin.2019.04.008. Epub 2019 Apr 12.


Relationship Between Different Resistance Mechanisms and Virulence in Acinetobacter baumannii.

Espinal P, Pantel A, Rolo D, Marti S, López-Rojas R, Smani Y, Pachón J, Vila J, Lavigne JP.

Microb Drug Resist. 2019 Jun;25(5):752-760. doi: 10.1089/mdr.2018.0182. Epub 2019 Jan 11.


Physicochemical and microbiological stability of two news oral liquid formulations of clonidine hydrochloride for pediatric patients.

Merino-Bohórquez V, Delgado-Valverde M, García-Palomo M, Dávila-Pousa MC, Cañete C, Villaronga M, Rodriguez-Marrodán B, López-Rojas R, Cameán-Fernández M; Pharmaceutical Technology Working Group and Pediatric Pharmacy Working Group of the Spanish Society of Hospital Pharmacy (SEFH).

Pharm Dev Technol. 2019 Apr;24(4):465-478. doi: 10.1080/10837450.2018.1514520. Epub 2018 Nov 19.


Relationship between Tolerance and Persistence Mechanisms in Acinetobacter baumannii Strains with AbkAB Toxin-Antitoxin System.

Fernández-García L, Fernandez-Cuenca F, Blasco L, López-Rojas R, Ambroa A, Lopez M, Pascual Á, Bou G, Tomás M.

Antimicrob Agents Chemother. 2018 Apr 26;62(5). pii: e00250-18. doi: 10.1128/AAC.00250-18. Print 2018 May.


Efficacy of ceftaroline versus vancomycin in an experimental foreign-body and systemic infection model caused by biofilm-producing methicillin-resistant Staphylococcus epidermidis.

Domínguez-Herrera J, López-Rojas R, Smani Y, Labrador-Herrera G, Pachón J.

Int J Antimicrob Agents. 2016 Dec;48(6):661-665. doi: 10.1016/j.ijantimicag.2016.09.011. Epub 2016 Oct 18.


Colistin Dosage without Loading Dose Is Efficacious when Treating Carbapenem-Resistant Acinetobacter baumannii Ventilator-Associated Pneumonia Caused by Strains with High Susceptibility to Colistin.

Álvarez-Marín R, López-Rojas R, Márquez JA, Gómez MJ, Molina J, Cisneros JM, Ortiz-Leyba C, Aznar J, Garnacho-Montero J, Pachón J.

PLoS One. 2016 Dec 19;11(12):e0168468. doi: 10.1371/journal.pone.0168468. eCollection 2016.


Impaired growth under iron-limiting conditions associated with the acquisition of colistin resistance in Acinetobacter baumannii.

López-Rojas R, García-Quintanilla M, Labrador-Herrera G, Pachón J, McConnell MJ.

Int J Antimicrob Agents. 2016 Jun;47(6):473-7. doi: 10.1016/j.ijantimicag.2016.03.010. Epub 2016 Apr 22.


Draft Genome Sequences of Seven Multidrug-Resistant Acinetobacter baumannii Strains, Isolated from Respiratory Samples in Spain.

Labrador-Herrera G, Álvarez R, López-Rojas R, Smani Y, Cebrero-Cangueiro T, Rueda A, Pérez Florido J, Pachón J, Pachón-Ibáñez ME.

Genome Announc. 2016 Mar 31;4(2). pii: e00083-16. doi: 10.1128/genomeA.00083-16.


In vitro activity of a polyhexanide-betaine solution against high-risk clones of multidrug-resistant nosocomial pathogens.

López-Rojas R, Fernández-Cuenca F, Serrano-Rocha L, Pascual Á.

Enferm Infecc Microbiol Clin. 2017 Jan;35(1):12-19. doi: 10.1016/j.eimc.2016.02.008. Epub 2016 Mar 19.


Sequence-activity relationship, and mechanism of action of mastoparan analogues against extended-drug resistant Acinetobacter baumannii.

Vila-Farrés X, López-Rojas R, Pachón-Ibáñez ME, Teixidó M, Pachón J, Vila J, Giralt E.

Eur J Med Chem. 2015 Aug 28;101:34-40. doi: 10.1016/j.ejmech.2015.06.016. Epub 2015 Jun 9.


Interplay between plasmid-mediated and chromosomal-mediated fluoroquinolone resistance and bacterial fitness in Escherichia coli.

Machuca J, Briales A, Labrador G, Díaz-de-Alba P, López-Rojas R, Docobo-Pérez F, Martínez-Martínez L, Rodríguez-Baño J, Pachón ME, Pascual A, Rodríguez-Martínez JM.

J Antimicrob Chemother. 2014 Dec;69(12):3203-15. doi: 10.1093/jac/dku308. Epub 2014 Aug 19.


Activity of host antimicrobials against multidrug-resistant Acinetobacter baumannii acquiring colistin resistance through loss of lipopolysaccharide.

García-Quintanilla M, Pulido MR, Moreno-Martínez P, Martín-Peña R, López-Rojas R, Pachón J, McConnell MJ.

Antimicrob Agents Chemother. 2014 May;58(5):2972-5. doi: 10.1128/AAC.02642-13. Epub 2014 Feb 24.


ARG-ANNOT, a new bioinformatic tool to discover antibiotic resistance genes in bacterial genomes.

Gupta SK, Padmanabhan BR, Diene SM, Lopez-Rojas R, Kempf M, Landraud L, Rolain JM.

Antimicrob Agents Chemother. 2014;58(1):212-20. doi: 10.1128/AAC.01310-13. Epub 2013 Oct 21.


Colistin resistance in a clinical Acinetobacter baumannii strain appearing after colistin treatment: effect on virulence and bacterial fitness.

López-Rojas R, McConnell MJ, Jiménez-Mejías ME, Domínguez-Herrera J, Fernández-Cuenca F, Pachón J.

Antimicrob Agents Chemother. 2013 Sep;57(9):4587-9. doi: 10.1128/AAC.00543-13. Epub 2013 Jul 8.


Impact of qnrA1, qnrB1 and qnrS1 on the efficacy of ciprofloxacin and levofloxacin in an experimental pneumonia model caused by Escherichia coli with or without the GyrA mutation Ser83Leu.

Domínguez-Herrera J, Velasco C, Docobo-Pérez F, Rodríguez-Martínez JM, López-Rojas R, Briales A, Pichardo C, Díaz-de-Alba P, Rodríguez-Baño J, Pascual A, Pachón J.

J Antimicrob Chemother. 2013 Jul;68(7):1609-15. doi: 10.1093/jac/dkt063. Epub 2013 Mar 14.


Treating multidrug-resistant Acinetobacter baumannii infection by blocking its virulence factors.

López-Rojas R, Smani Y, Pachón J.

Expert Rev Anti Infect Ther. 2013 Mar;11(3):231-3. doi: 10.1586/eri.13.11. Review. No abstract available.


Inoculum effect on the efficacies of amoxicillin-clavulanate, piperacillin-tazobactam, and imipenem against extended-spectrum β-lactamase (ESBL)-producing and non-ESBL-producing Escherichia coli in an experimental murine sepsis model.

Docobo-Pérez F, López-Cerero L, López-Rojas R, Egea P, Domínguez-Herrera J, Rodríguez-Baño J, Pascual A, Pachón J.

Antimicrob Agents Chemother. 2013 May;57(5):2109-13. doi: 10.1128/AAC.02190-12. Epub 2013 Feb 25.


Emerging therapies for multidrug resistant Acinetobacter baumannii.

García-Quintanilla M, Pulido MR, López-Rojas R, Pachón J, McConnell MJ.

Trends Microbiol. 2013 Mar;21(3):157-63. doi: 10.1016/j.tim.2012.12.002. Epub 2013 Jan 11. Review.


Platelet-activating factor receptor initiates contact of Acinetobacter baumannii expressing phosphorylcholine with host cells.

Smani Y, Docobo-Pérez F, López-Rojas R, Domínguez-Herrera J, Ibáñez-Martínez J, Pachón J.

J Biol Chem. 2012 Aug 3;287(32):26901-10. doi: 10.1074/jbc.M112.344556. Epub 2012 Jun 11.


Efficacy of linezolid versus a pharmacodynamically optimized vancomycin therapy in an experimental pneumonia model caused by methicillin-resistant Staphylococcus aureus.

Docobo-Pérez F, López-Rojas R, Domínguez-Herrera J, Jiménez-Mejias ME, Pichardo C, Ibáñez-Martínez J, Pachón J.

J Antimicrob Chemother. 2012 Aug;67(8):1961-7. doi: 10.1093/jac/dks142. Epub 2012 Apr 24.


Role of acinetobactin-mediated iron acquisition functions in the interaction of Acinetobacter baumannii strain ATCC 19606T with human lung epithelial cells, Galleria mellonella caterpillars, and mice.

Gaddy JA, Arivett BA, McConnell MJ, López-Rojas R, Pachón J, Actis LA.

Infect Immun. 2012 Mar;80(3):1015-24. doi: 10.1128/IAI.06279-11. Epub 2012 Jan 9.


Efficacies of colistin and tigecycline in mice with experimental pneumonia due to NDM-1-producing strains of Klebsiella pneumoniae and Escherichia coli.

Docobo-Pérez F, Nordmann P, Domínguez-Herrera J, López-Rojas R, Smani Y, Poirel L, Pachón J.

Int J Antimicrob Agents. 2012 Mar;39(3):251-4. doi: 10.1016/j.ijantimicag.2011.10.012. Epub 2011 Dec 7.


Efficacy of daptomycin versus vancomycin in an experimental model of foreign-body and systemic infection caused by biofilm producers and methicillin-resistant Staphylococcus epidermidis.

Domínguez-Herrera J, Docobo-Pérez F, López-Rojas R, Pichardo C, Ruiz-Valderas R, Lepe JA, Pachón J.

Antimicrob Agents Chemother. 2012 Feb;56(2):613-7. doi: 10.1128/AAC.05606-11. Epub 2011 Nov 28.


In vitro and in vivo reduced fitness and virulence in ciprofloxacin-resistant Acinetobacter baumannii.

Smani Y, López-Rojas R, Domínguez-Herrera J, Docobo-Pérez F, Martí S, Vila J, Pachón J.

Clin Microbiol Infect. 2012 Jan;18(1):E1-4. doi: 10.1111/j.1469-0691.2011.03695.x. Epub 2011 Nov 15.


Acinetobacter baumannii resistant to colistin alters its antibiotic resistance profile: a case report from Spain.

López-Rojas R, Jiménez-Mejías ME, Lepe JA, Pachón J.

J Infect Dis. 2011 Oct 1;204(7):1147-8. doi: 10.1093/infdis/jir476. No abstract available.


Pre-clinical studies of a new quinolone (UB-8902) against Acinetobacter baumannii resistant to ciprofloxacin.

López-Rojas R, Sánchez-Céspedes J, Docobo-Pérez F, Domínguez-Herrera J, Vila J, Pachón J.

Int J Antimicrob Agents. 2011 Oct;38(4):355-9. doi: 10.1016/j.ijantimicag.2011.06.006. Epub 2011 Aug 6.


In vitro activity of several antimicrobial peptides against colistin-susceptible and colistin-resistant Acinetobacter baumannii.

Vila-Farres X, Garcia de la Maria C, López-Rojas R, Pachón J, Giralt E, Vila J.

Clin Microbiol Infect. 2012 Apr;18(4):383-7. doi: 10.1111/j.1469-0691.2011.03581.x. Epub 2011 Jun 14.


Efficacy of cecropin A-melittin peptides on a sepsis model of infection by pan-resistant Acinetobacter baumannii.

López-Rojas R, Docobo-Pérez F, Pachón-Ibáñez ME, de la Torre BG, Fernández-Reyes M, March C, Bengoechea JA, Andreu D, Rivas L, Pachón J.

Eur J Clin Microbiol Infect Dis. 2011 Nov;30(11):1391-8. doi: 10.1007/s10096-011-1233-y. Epub 2011 Apr 12.


Impaired virulence and in vivo fitness of colistin-resistant Acinetobacter baumannii.

López-Rojas R, Domínguez-Herrera J, McConnell MJ, Docobo-Peréz F, Smani Y, Fernández-Reyes M, Rivas L, Pachón J.

J Infect Dis. 2011 Feb 15;203(4):545-8. doi: 10.1093/infdis/jiq086. Epub 2011 Jan 7.


Vaccination with outer membrane complexes elicits rapid protective immunity to multidrug-resistant Acinetobacter baumannii.

McConnell MJ, Domínguez-Herrera J, Smani Y, López-Rojas R, Docobo-Pérez F, Pachón J.

Infect Immun. 2011 Jan;79(1):518-26. doi: 10.1128/IAI.00741-10. Epub 2010 Oct 25.


Local imipenem activity against Pseudomonas aeruginosa decreases in vivo in the presence of siliconized latex.

Pichardo C, Conejo MC, Docobo-Pérez F, Velasco C, López-Rojas R, García I, Pachón-Ibáñez ME, Rodríguez JM, Pachón J, Pascual A.

Eur J Clin Microbiol Infect Dis. 2011 Feb;30(2):289-91. doi: 10.1007/s10096-010-1084-y. Epub 2010 Oct 10.


Efficacy of tigecycline vs. imipenem in the treatment of experimental Acinetobacter baumannii murine pneumonia.

Pichardo C, Pachón-Ibañez ME, Docobo-Perez F, López-Rojas R, Jiménez-Mejías ME, Garcia-Curiel A, Pachon J.

Eur J Clin Microbiol Infect Dis. 2010 May;29(5):527-31. doi: 10.1007/s10096-010-0890-6. Epub 2010 Feb 25.


Efficacy of rifampin and its combinations with imipenem, sulbactam, and colistin in experimental models of infection caused by imipenem-resistant Acinetobacter baumannii.

Pachón-Ibáñez ME, Docobo-Pérez F, López-Rojas R, Domínguez-Herrera J, Jiménez-Mejias ME, García-Curiel A, Pichardo C, Jiménez L, Pachón J.

Antimicrob Agents Chemother. 2010 Mar;54(3):1165-72. doi: 10.1128/AAC.00367-09. Epub 2010 Jan 4.


In vitro activity and in vivo efficacy of clavulanic acid against Acinetobacter baumannii.

Beceiro A, López-Rojas R, Domínguez-Herrera J, Docobo-Pérez F, Bou G, Pachón J; Spanish Network for Research in Infectious Diseases (REIPI).

Antimicrob Agents Chemother. 2009 Oct;53(10):4298-304. doi: 10.1128/AAC.00320-09. Epub 2009 Jul 27.

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