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Items: 35

1.

TERRA regulate the transcriptional landscape of pluripotent cells through TRF1-dependent recruitment of PRC2.

Marión RM, Montero JJ, López de Silanes I, Graña-Castro O, Martínez P, Schoeftner S, Palacios-Fábrega JA, Blasco MA.

Elife. 2019 Aug 20;8. pii: e44656. doi: 10.7554/eLife.44656.

2.

Common Telomere Changes during In Vivo Reprogramming and Early Stages of Tumorigenesis.

Marión RM, López de Silanes I, Mosteiro L, Gamache B, Abad M, Guerra C, Megías D, Serrano M, Blasco MA.

Stem Cell Reports. 2017 Feb 14;8(2):460-475. doi: 10.1016/j.stemcr.2017.01.001. Epub 2017 Feb 2.

3.

Telomeric RNAs are essential to maintain telomeres.

Montero JJ, López de Silanes I, Graña O, Blasco MA.

Nat Commun. 2016 Aug 17;7:12534. doi: 10.1038/ncomms12534.

4.

Identification of TERRA locus unveils a telomere protection role through association to nearly all chromosomes.

López de Silanes I, Graña O, De Bonis ML, Dominguez O, Pisano DG, Blasco MA.

Nat Commun. 2014 Sep 3;5:4723. doi: 10.1038/ncomms5723.

5.

Destabilization of nucleophosmin mRNA by the HuR/KSRP complex is required for muscle fibre formation.

Cammas A, Sanchez BJ, Lian XJ, Dormoy-Raclet V, van der Giessen K, López de Silanes I, Ma J, Wilusz C, Richardson J, Gorospe M, Millevoi S, Giovarelli M, Gherzi R, Di Marco S, Gallouzi IE.

Nat Commun. 2014 Jun 27;5:4190. doi: 10.1038/ncomms5190.

6.

TERRA transcripts are bound by a complex array of RNA-binding proteins.

López de Silanes I, Stagno d'Alcontres M, Blasco MA.

Nat Commun. 2010 Jun 29;1:33. doi: 10.1038/ncomms1032.

PMID:
20975687
7.

Telomere shortening relaxes X chromosome inactivation and forces global transcriptome alterations.

Schoeftner S, Blanco R, Lopez de Silanes I, Muñoz P, Gómez-López G, Flores JM, Blasco MA.

Proc Natl Acad Sci U S A. 2009 Nov 17;106(46):19393-8. doi: 10.1073/pnas.0909265106. Epub 2009 Nov 3.

8.

p38 Mitogen-activated protein kinase- and HuR-dependent stabilization of p21(Cip1) mRNA mediates the G(1)/S checkpoint.

Lafarga V, Cuadrado A, Lopez de Silanes I, Bengoechea R, Fernandez-Capetillo O, Nebreda AR.

Mol Cell Biol. 2009 Aug;29(16):4341-51. doi: 10.1128/MCB.00210-09. Epub 2009 Jun 15.

9.

The RNA-binding protein HuR regulates DNA methylation through stabilization of DNMT3b mRNA.

López de Silanes I, Gorospe M, Taniguchi H, Abdelmohsen K, Srikantan S, Alaminos M, Berdasco M, Urdinguio RG, Fraga MF, Jacinto FV, Esteller M.

Nucleic Acids Res. 2009 May;37(8):2658-71. doi: 10.1093/nar/gkp123. Epub 2009 Mar 6.

10.

Epigenetic inactivation of the Groucho homologue gene TLE1 in hematologic malignancies.

Fraga MF, Berdasco M, Ballestar E, Ropero S, Lopez-Nieva P, Lopez-Serra L, Martín-Subero JI, Calasanz MJ, Lopez de Silanes I, Setien F, Casado S, Fernandez AF, Siebert R, Stifani S, Esteller M.

Cancer Res. 2008 Jun 1;68(11):4116-22. doi: 10.1158/0008-5472.CAN-08-0085.

11.

Kinetic analysis of butyrate transport in human colon adenocarcinoma cells reveals two different carrier-mediated mechanisms.

Lecona E, Olmo N, Turnay J, Santiago-Gómez A, López de Silanes I, Gorospe M, Lizarbe MA.

Biochem J. 2008 Jan 1;409(1):311-20.

PMID:
17760565
12.

The Wnt antagonist DICKKOPF-1 gene is induced by 1alpha,25-dihydroxyvitamin D3 associated to the differentiation of human colon cancer cells.

Aguilera O, Peña C, García JM, Larriba MJ, Ordóñez-Morán P, Navarro D, Barbáchano A, López de Silanes I, Ballestar E, Fraga MF, Esteller M, Gamallo C, Bonilla F, González-Sancho JM, Muñoz A.

Carcinogenesis. 2007 Sep;28(9):1877-84. Epub 2007 Apr 21.

PMID:
17449905
13.

Aberrant regulation of messenger RNA 3'-untranslated region in human cancer.

López de Silanes I, Quesada MP, Esteller M.

Cell Oncol. 2007;29(1):1-17. Review.

14.

HuR: post-transcriptional paths to malignancy.

López de Silanes I, Lal A, Gorospe M.

RNA Biol. 2005 Jan;2(1):11-3. Epub 2005 Jan 19.

PMID:
17132932
15.

In vitro models for the study of the effect of butyrate on human colon adenocarcinoma cells.

Olmo N, Turnay J, Pérez-Ramos P, Lecona E, Barrasa JI, López de Silanes I, Lizarbe MA.

Toxicol In Vitro. 2007 Mar;21(2):262-70. Epub 2006 Sep 29.

PMID:
17084582
16.

Esg1, expressed exclusively in preimplantation embryos, germline, and embryonic stem cells, is a putative RNA-binding protein with broad RNA targets.

Tanaka TS, Lopez de Silanes I, Sharova LV, Akutsu H, Yoshikawa T, Amano H, Yamanaka S, Gorospe M, Ko MS.

Dev Growth Differ. 2006 Aug;48(6):381-90.

PMID:
16872451
17.

Identification and functional outcome of mRNAs associated with RNA-binding protein TIA-1.

López de Silanes I, Galbán S, Martindale JL, Yang X, Mazan-Mamczarz K, Indig FE, Falco G, Zhan M, Gorospe M.

Mol Cell Biol. 2005 Nov;25(21):9520-31.

18.

Enhanced proliferation of cultured human vascular smooth muscle cells linked to increased function of RNA-binding protein HuR.

Pullmann R Jr, Juhaszova M, López de Silanes I, Kawai T, Mazan-Mamczarz K, Halushka MK, Gorospe M.

J Biol Chem. 2005 Jun 17;280(24):22819-26. Epub 2005 Apr 11.

19.

Differentiation of human colon adenocarcinoma cells alters the expression and intracellular localization of annexins A1, A2, and A5.

Guzmán-Aránguez A, Olmo N, Turnay J, Lecona E, Pérez-Ramos P, López de Silanes I, Lizarbe MA.

J Cell Biochem. 2005 Jan 1;94(1):178-93.

PMID:
15526283
20.

Global analysis of HuR-regulated gene expression in colon cancer systems of reducing complexity.

López de Silanes I, Fan J, Galbán CJ, Spencer RG, Becker KG, Gorospe M.

Gene Expr. 2004;12(1):49-59.

21.

Calcification and identification of metalloproteinases in bovine pericardium after subcutaneous implantation in rats.

Jorge-Herrero E, Turnay J, Calero P, Olmo N, López De Silanes I, Martín Maestro M, Lizarbe MA, Castillo-Olivares JL.

J Mater Sci Mater Med. 2001 Oct-Dec;12(10-12):1013-7.

PMID:
15348357
22.

AMP-activated protein kinase-regulated phosphorylation and acetylation of importin alpha1: involvement in the nuclear import of RNA-binding protein HuR.

Wang W, Yang X, Kawai T, López de Silanes I, Mazan-Mamczarz K, Chen P, Chook YM, Quensel C, Köhler M, Gorospe M.

J Biol Chem. 2004 Nov 12;279(46):48376-88. Epub 2004 Sep 1.

23.

Acquisition of resistance to butyrate enhances survival after stress and induces malignancy of human colon carcinoma cells.

López de Silanes I, Olmo N, Turnay J, González de Buitrago G, Pérez-Ramos P, Guzmán-Aránguez A, García-Díez M, Lecona E, Gorospe M, Lizarbe MA.

Cancer Res. 2004 Jul 1;64(13):4593-600.

24.

Identification of a target RNA motif for RNA-binding protein HuR.

López de Silanes I, Zhan M, Lal A, Yang X, Gorospe M.

Proc Natl Acad Sci U S A. 2004 Mar 2;101(9):2987-92. Epub 2004 Feb 23.

25.

Role of the RNA-binding protein HuR in colon carcinogenesis.

López de Silanes I, Fan J, Yang X, Zonderman AB, Potapova O, Pizer ES, Gorospe M.

Oncogene. 2003 Oct 16;22(46):7146-54.

PMID:
14562043
26.

Regulation of eotaxin gene expression by TNF-alpha and IL-4 through mRNA stabilization: involvement of the RNA-binding protein HuR.

Atasoy U, Curry SL, López de Silanes I, Shyu AB, Casolaro V, Gorospe M, Stellato C.

J Immunol. 2003 Oct 15;171(8):4369-78.

27.

Influence of the RNA-binding protein HuR in pVHL-regulated p53 expression in renal carcinoma cells.

Galbán S, Martindale JL, Mazan-Mamczarz K, López de Silanes I, Fan J, Wang W, Decker J, Gorospe M.

Mol Cell Biol. 2003 Oct;23(20):7083-95.

28.

RNA-binding protein HuR enhances p53 translation in response to ultraviolet light irradiation.

Mazan-Mamczarz K, Galbán S, López de Silanes I, Martindale JL, Atasoy U, Keene JD, Gorospe M.

Proc Natl Acad Sci U S A. 2003 Jul 8;100(14):8354-9. Epub 2003 Jun 23.

29.

Increased AMP:ATP ratio and AMP-activated protein kinase activity during cellular senescence linked to reduced HuR function.

Wang W, Yang X, López de Silanes I, Carling D, Gorospe M.

J Biol Chem. 2003 Jul 18;278(29):27016-23. Epub 2003 May 1.

30.

Interaction of fibronectin with human colon adenocarcinoma cells: effect on the in vivo tumorigenic capacity.

López-Conejo MT, Olmo N, Turnay J, López De Silanes I, Lizarbe MA.

Oncology. 2002;62(4):371-80.

PMID:
12138246
31.

Gelatinases in soft tissue biomaterials. Analysis of different crosslinking agents.

Calero P, Jorge-Herrero E, Turnay J, Olmo N, López de Silanes I, Lizarbe MA, Maestro MM, Arenaz B, Castillo-Olivares JL.

Biomaterials. 2002 Aug;23(16):3473-8.

PMID:
12099291
32.

AMP-activated kinase regulates cytoplasmic HuR.

Wang W, Fan J, Yang X, Fürer-Galban S, Lopez de Silanes I, von Kobbe C, Guo J, Georas SN, Foufelle F, Hardie DG, Carling D, Gorospe M.

Mol Cell Biol. 2002 May;22(10):3425-36.

33.

Midregion parathyroid hormone-related protein inhibits growth and invasion in vitro and tumorigenesis in vivo of human breast cancer cells.

Luparello C, Romanotto R, Tipa A, Sirchia R, Olmo N, López de Silanes I, Turnay J, Lizarbe MA, Stewart AF.

J Bone Miner Res. 2001 Dec;16(12):2173-81.

34.

Cytotoxic mechanism of the ribotoxin alpha-sarcin. Induction of cell death via apoptosis.

Olmo N, Turnay J, González de Buitrago G, López de Silanes I, Gavilanes JG, Lizarbe MA.

Eur J Biochem. 2001 Apr;268(7):2113-23.

35.

Diastereoselective Synthesis of alpha,alpha-Disubstituted gamma-Carboxypyroglutamates via Sm(III)-Azomethine Ylide Cycloadditions.

Alvarez-Ibarra C, Csákÿ AG, López De Silanes I, Quiroga ML.

J Org Chem. 1997 Feb 7;62(3):479-484.

PMID:
11671437

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