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Items: 42


A modular transcriptional signature identifies phenotypic heterogeneity of human tuberculosis infection.

Singhania A, Verma R, Graham CM, Lee J, Tran T, Richardson M, Lecine P, Leissner P, Berry MPR, Wilkinson RJ, Kaiser K, Rodrigue M, Woltmann G, Haldar P, O'Garra A.

Nat Commun. 2018 Jun 19;9(1):2308. doi: 10.1038/s41467-018-04579-w.


EFA6 proteins regulate lumen formation through α-actinin 1.

Milanini J, Fayad R, Partisani M, Lecine P, Borg JP, Franco M, Luton F.

J Cell Sci. 2018 Feb 8;131(3). pii: jcs209361. doi: 10.1242/jcs.209361.


Modulation of estrogen related receptor alpha activity by the kinesin KIF17.

Seneviratne APB, Turan Z, Hermant A, Lecine P, Smith WO, Borg JP, Jaulin F, Kreitzer G.

Oncotarget. 2017 May 23;8(31):50359-50375. doi: 10.18632/oncotarget.18104. eCollection 2017 Aug 1.


Clinical, virological, and biological parameters associated with outcomes of Ebola virus infection in Macenta, Guinea.

Vernet MA, Reynard S, Fizet A, Schaeffer J, Pannetier D, Guedj J, Rives M, Georges N, Garcia-Bonnet N, Sylla AI, Grovogui P, Kerherve JY, Savio C, Savio-Coste S, de Séverac ML, Zloczewski P, Linares S, Harouna S, Abdoul BM, Petitjean F, Samake N, Shepherd S, Kinda M, Koundouno FR, Joxe L, Mateo M, Lecine P, Page A, Tchamdja TM, Schoenhals M, Barbe S, Simon B, Tran-Minh T, Longuet C, L'Hériteau F, Baize S.

JCI Insight. 2017 Mar 23;2(6):e88864. doi: 10.1172/jci.insight.88864.


Characterization and Genetic Analyses of New Genes Coding for NOD2 Interacting Proteins.

Thiébaut R, Esmiol S, Lecine P, Mahfouz B, Hermant A, Nicoletti C, Parnis S, Perroy J, Borg JP, Pascoe L, Hugot JP, Ollendorff V.

PLoS One. 2016 Nov 3;11(11):e0165420. doi: 10.1371/journal.pone.0165420. eCollection 2016.


Coronavirus Nsp10, a critical co-factor for activation of multiple replicative enzymes.

Bouvet M, Lugari A, Posthuma CC, Zevenhoven JC, Bernard S, Betzi S, Imbert I, Canard B, Guillemot JC, Lécine P, Pfefferle S, Drosten C, Snijder EJ, Decroly E, Morelli X.

J Biol Chem. 2014 Sep 12;289(37):25783-96. doi: 10.1074/jbc.M114.577353. Epub 2014 Jul 29.


MCC inhibits beta-catenin transcriptional activity by sequestering DBC1 in the cytoplasm.

Pangon L, Mladenova D, Watkins L, Van Kralingen C, Currey N, Al-Sohaily S, Lecine P, Borg JP, Kohonen-Corish MR.

Int J Cancer. 2015 Jan 1;136(1):55-64. doi: 10.1002/ijc.28967. Epub 2014 May 27.


Semaphorin 3E suppresses tumor cell death triggered by the plexin D1 dependence receptor in metastatic breast cancers.

Luchino J, Hocine M, Amoureux MC, Gibert B, Bernet A, Royet A, Treilleux I, Lécine P, Borg JP, Mehlen P, Chauvet S, Mann F.

Cancer Cell. 2013 Nov 11;24(5):673-85. doi: 10.1016/j.ccr.2013.09.010. Epub 2013 Oct 17.


Brucella β 1,2 cyclic glucan is an activator of human and mouse dendritic cells.

Martirosyan A, Pérez-Gutierrez C, Banchereau R, Dutartre H, Lecine P, Dullaers M, Mello M, Salcedo SP, Muller A, Leserman L, Levy Y, Zurawski G, Zurawski S, Moreno E, Moriyón I, Klechevsky E, Banchereau J, Oh S, Gorvel JP.

PLoS Pathog. 2012;8(11):e1002983. doi: 10.1371/journal.ppat.1002983. Epub 2012 Nov 15.


Structural recognition mechanisms between human Src homology domain 3 (SH3) and ALG-2-interacting protein X (Alix).

Shi X, Betzi S, Lugari A, Opi S, Restouin A, Parrot I, Martinez J, Zimmermann P, Lecine P, Huang M, Arold ST, Collette Y, Morelli X.

FEBS Lett. 2012 Jun 21;586(13):1759-64. doi: 10.1016/j.febslet.2012.05.017. Epub 2012 May 26.


Hook2 is involved in the morphogenesis of the primary cilium.

Baron Gaillard CL, Pallesi-Pocachard E, Massey-Harroche D, Richard F, Arsanto JP, Chauvin JP, Lecine P, Krämer H, Borg JP, Le Bivic A.

Mol Biol Cell. 2011 Dec;22(23):4549-62. doi: 10.1091/mbc.E11-05-0405. Epub 2011 Oct 12.


Protein tyrosine kinase 7 has a conserved role in Wnt/β-catenin canonical signalling.

Puppo F, Thomé V, Lhoumeau AC, Cibois M, Gangar A, Lembo F, Belotti E, Marchetto S, Lécine P, Prébet T, Sebbagh M, Shin WS, Lee ST, Kodjabachian L, Borg JP.

EMBO Rep. 2011 Jan;12(1):43-9. doi: 10.1038/embor.2010.185. Epub 2010 Dec 3.


Molecular mapping of the RNA Cap 2'-O-methyltransferase activation interface between severe acute respiratory syndrome coronavirus nsp10 and nsp16.

Lugari A, Betzi S, Decroly E, Bonnaud E, Hermant A, Guillemot JC, Debarnot C, Borg JP, Bouvet M, Canard B, Morelli X, Lécine P.

J Biol Chem. 2010 Oct 22;285(43):33230-41. doi: 10.1074/jbc.M110.120014. Epub 2010 Aug 10.


MCC, a new interacting protein for Scrib, is required for cell migration in epithelial cells.

Arnaud C, Sebbagh M, Nola S, Audebert S, Bidaut G, Hermant A, Gayet O, Dusetti NJ, Ollendorff V, Santoni MJ, Borg JP, Lécine P.

FEBS Lett. 2009 Jul 21;583(14):2326-32. doi: 10.1016/j.febslet.2009.06.034. Epub 2009 Jun 24.


Biochemical studies and molecular dynamics simulations of Smad3-Erbin interaction identify a non-classical Erbin PDZ binding.

Déliot N, Chavent M, Nourry C, Lécine P, Arnaud C, Hermant A, Maigret B, Borg JP.

Biochem Biophys Res Commun. 2009 Jan 16;378(3):360-5. doi: 10.1016/j.bbrc.2008.10.175. Epub 2008 Nov 14.


The Amot/Patj/Syx signaling complex spatially controls RhoA GTPase activity in migrating endothelial cells.

Ernkvist M, Luna Persson N, Audebert S, Lecine P, Sinha I, Liu M, Schlueter M, Horowitz A, Aase K, Weide T, Borg JP, Majumdar A, Holmgren L.

Blood. 2009 Jan 1;113(1):244-53. doi: 10.1182/blood-2008-04-153874. Epub 2008 Sep 29.


Identification of multi-SH3 domain-containing protein interactome in pancreatic cancer: a yeast two-hybrid approach.

Thalappilly S, Suliman M, Gayet O, Soubeyran P, Hermant A, Lecine P, Iovanna JL, Dusetti NJ.

Proteomics. 2008 Aug;8(15):3071-81. doi: 10.1002/pmic.200701157.


The SARS-Coronavirus PLnc domain of nsp3 as a replication/transcription scaffolding protein.

Imbert I, Snijder EJ, Dimitrova M, Guillemot JC, Lécine P, Canard B.

Virus Res. 2008 May;133(2):136-48. doi: 10.1016/j.virusres.2007.11.017. Epub 2008 Feb 5.


The NOD2-RICK complex signals from the plasma membrane.

Lécine P, Esmiol S, Métais JY, Nicoletti C, Nourry C, McDonald C, Nunez G, Hugot JP, Borg JP, Ollendorff V.

J Biol Chem. 2007 May 18;282(20):15197-207. Epub 2007 Mar 13.


The Salmonella effector protein PipB2 is a linker for kinesin-1.

Henry T, Couillault C, Rockenfeller P, Boucrot E, Dumont A, Schroeder N, Hermant A, Knodler LA, Lecine P, Steele-Mortimer O, Borg JP, Gorvel JP, Méresse S.

Proc Natl Acad Sci U S A. 2006 Sep 5;103(36):13497-502. Epub 2006 Aug 25.


A role for Erbin in the regulation of Nod2-dependent NF-kappaB signaling.

McDonald C, Chen FF, Ollendorff V, Ogura Y, Marchetto S, Lécine P, Borg JP, Nuñez G.

J Biol Chem. 2005 Dec 2;280(48):40301-9. Epub 2005 Oct 3.


Mammalian Scribble forms a tight complex with the betaPIX exchange factor.

Audebert S, Navarro C, Nourry C, Chasserot-Golaz S, Lécine P, Bellaiche Y, Dupont JL, Premont RT, Sempéré C, Strub JM, Van Dorsselaer A, Vitale N, Borg JP.

Curr Biol. 2004 Jun 8;14(11):987-95.


Novel CD28-responsive enhancer activated by CREB/ATF and AP-1 families in the human interleukin-2 receptor alpha-chain locus.

Yeh JH, Lecine P, Nunes JA, Spicuglia S, Ferrier P, Olive D, Imbert J.

Mol Cell Biol. 2001 Jul;21(14):4515-27.


A lineage-restricted and divergent beta-tubulin isoform is essential for the biogenesis, structure and function of blood platelets.

Schwer HD, Lecine P, Tiwari S, Italiano JE Jr, Hartwig JH, Shivdasani RA.

Curr Biol. 2001 Apr 17;11(8):579-86.


Specific deficiency of p56lck expression in T lymphocytes from type 1 diabetic patients.

Nervi S, Atlan-Gepner C, Kahn-Perles B, Lecine P, Vialettes B, Imbert J, Naquet P.

J Immunol. 2000 Nov 15;165(10):5874-83.


Hematopoietic-specific beta 1 tubulin participates in a pathway of platelet biogenesis dependent on the transcription factor NF-E2.

Lecine P, Italiano JE Jr, Kim SW, Villeval JL, Shivdasani RA.

Blood. 2000 Aug 15;96(4):1366-73.


IL-2 and long-term T cell activation induce physical and functional interaction between STAT5 and ETS transcription factors in human T cells.

Rameil P, Lécine P, Ghysdael J, Gouilleux F, Kahn-Perlès B, Imbert J.

Oncogene. 2000 Apr 20;19(17):2086-97.


Blood platelets are assembled principally at the ends of proplatelet processes produced by differentiated megakaryocytes.

Italiano JE Jr, Lecine P, Shivdasani RA, Hartwig JH.

J Cell Biol. 1999 Dec 13;147(6):1299-312.


Pathophysiology of thrombocytopenia and anemia in mice lacking transcription factor NF-E2.

Levin J, Peng JP, Baker GR, Villeval JL, Lecine P, Burstein SA, Shivdasani RA.

Blood. 1999 Nov 1;94(9):3037-47.


Characterization of the hematopoietic transcription factor NF-E2 in primary murine megakaryocytes.

Lecine P, Blank V, Shivdasani R.

J Biol Chem. 1998 Mar 27;273(13):7572-8.


Secretion of extracellular factor(s) induced by X-irradiation activates the HIV type 1 long terminal repeat through its kappaB motif.

Faure E, Rameil P, Lecine P, Rey F, Sire J, Kahn-Perles B, Imbert J.

AIDS Res Hum Retroviruses. 1998 Mar 1;14(4):353-65.


Temporal and subunit-specific modulations of the Rel/NF-kappaB transcription factors through CD28 costimulation.

Kahn-Perlès B, Lipcey C, Lécine P, Olive D, Imbert J.

J Biol Chem. 1997 Aug 29;272(35):21774-83.


Detection of CBFbeta/MYH11 fusion transcripts in acute myeloid leukemia: heterogeneity of cytological and molecular characteristics.

Costello R, Sainty D, Lecine P, Cusenier A, Mozziconacci MJ, Arnoulet C, Maraninchi D, Gastaut JA, Imbert J, Lafage-Pochitaloff M, Gabert J.

Leukemia. 1997 May;11(5):644-50.


Elf-1 and Stat5 bind to a critical element in a new enhancer of the human interleukin-2 receptor alpha gene.

Lécine P, Algarté M, Rameil P, Beadling C, Bucher P, Nabholz M, Imbert J.

Mol Cell Biol. 1997 Apr;17(4):2351. No abstract available.


Cell-to-cell contact activates the long terminal repeat of human immunodeficiency virus 1 through its kappaB motif.

Faure E, Lecine P, Lipcey C, Champion S, Imbert J.

Eur J Biochem. 1997 Mar 1;244(2):568-74.


Elf-1 and Stat5 bind to a critical element in a new enhancer of the human interleukin-2 receptor alpha gene.

Lécine P, Algarté M, Rameil P, Beadling C, Bucher P, Nabholz M, Imbert J.

Mol Cell Biol. 1996 Dec;16(12):6829-40. Erratum in: Mol Cell Biol. 1997 Apr;17(4):2351.


Activation of the HIV type 1 long terminal repeat by X-irradiation involves two main Re1/NF-kappa B DNA-binding complexes.

Faure E, Lecine P, Imbert J, Champion S.

AIDS Res Hum Retroviruses. 1996 Nov 1;12(16):1519-27.


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