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Items: 1 to 50 of 257

1.

Prolonged Duodenal Mucosal Lymphocyte Alterations in Patients With and Without Postinfectious Functional Gastrointestinal Disorders After Giardia Infection.

Dizdar V, Hausken T, Laerum OD, Gilja OH, Langeland N, Hanevik K.

J Infect Dis. 2019 Jun 19;220(2):321-329. doi: 10.1093/infdis/jiy690.

2.

International consensus guidelines for scoring the histopathological growth patterns of liver metastasis.

van Dam PJ, van der Stok EP, Teuwen LA, Van den Eynden GG, Illemann M, Frentzas S, Majeed AW, Eefsen RL, Coebergh van den Braak RRJ, Lazaris A, Fernandez MC, Galjart B, Laerum OD, Rayes R, Grünhagen DJ, Van de Paer M, Sucaet Y, Mudhar HS, Schvimer M, Nyström H, Kockx M, Bird NC, Vidal-Vanaclocha F, Metrakos P, Simoneau E, Verhoef C, Dirix LY, Van Laere S, Gao ZH, Brodt P, Reynolds AR, Vermeulen PB.

Br J Cancer. 2017 Nov 7;117(10):1427-1441. doi: 10.1038/bjc.2017.334. Epub 2017 Oct 5.

3.

Expression of circadian clock genes and proteins in urothelial cancer is related to cancer-associated genes.

Litlekalsoy J, Rostad K, Kalland KH, Hostmark JG, Laerum OD.

BMC Cancer. 2016 Jul 27;16:549. doi: 10.1186/s12885-016-2580-y.

4.

Tissue Inhibitor of Metalloproteinase-1 Is Confined to Tumor-Associated Myofibroblasts and Is Increased With Progression in Gastric Adenocarcinoma.

Alpízar-Alpízar W, Laerum OD, Christensen IJ, Ovrebo K, Skarstein A, Høyer-Hansen G, Ploug M, Illemann M.

J Histochem Cytochem. 2016 Aug;64(8):483-94. doi: 10.1369/0022155416656173. Epub 2016 Jul 1.

5.

C4.4A gene ablation is compatible with normal epidermal development and causes modest overt phenotypes.

Kriegbaum MC, Jacobsen B, Füchtbauer A, Hansen GH, Christensen IJ, Rundsten CF, Persson M, Engelholm LH, Madsen AN, Di Meo I, Lund IK, Holst B, Kjaer A, Lærum OD, Füchtbauer EM, Ploug M.

Sci Rep. 2016 May 12;6:25833. doi: 10.1038/srep25833.

6.

Microvessel density and endothelial cell proliferation levels in colorectal liver metastases from patients given neo-adjuvant cytotoxic chemotherapy and bevacizumab.

Eefsen RL, Engelholm L, Willemoe GL, Van den Eynden GG, Laerum OD, Christensen IJ, Rolff HC, Høyer-Hansen G, Osterlind K, Vainer B, Illemann M.

Int J Cancer. 2016 Apr 1;138(7):1777-84. doi: 10.1002/ijc.29904. Epub 2015 Nov 17.

7.

Targeting a novel bone degradation pathway in primary bone cancer by inactivation of the collagen receptor uPARAP/Endo180.

Engelholm LH, Melander MC, Hald A, Persson M, Madsen DH, Jürgensen HJ, Johansson K, Nielsen C, Nørregaard KS, Ingvarsen SZ, Kjaer A, Trovik CS, Laerum OD, Bugge TH, Eide J, Behrendt N.

J Pathol. 2016 Jan;238(1):120-33. doi: 10.1002/path.4661. Epub 2015 Nov 30.

PMID:
26466547
8.

uPAR Expression Pattern in Patients with Urothelial Carcinoma of the Bladder--Possible Clinical Implications.

Dohn LH, Pappot H, Iversen BR, Illemann M, Høyer-Hansen G, Christensen IJ, Thind P, Salling L, von der Maase H, Laerum OD.

PLoS One. 2015 Aug 20;10(8):e0135824. doi: 10.1371/journal.pone.0135824. eCollection 2015.

9.

Inflammation and uPAR-Expression in Colorectal Liver Metastases in Relation to Growth Pattern and Neo-adjuvant Therapy.

Eefsen RL, Engelholm L, Alpizar-Alpizar W, Van den Eynden GG, Vermeulen PB, Christensen IJ, Laerum OD, Rolff HC, Høyer-Hansen G, Vainer B, Osterlind K, Illemann M.

Cancer Microenviron. 2015 Aug;8(2):93-100. doi: 10.1007/s12307-015-0172-z. Epub 2015 Aug 14.

10.

Spontaneous lung and lymph node metastasis in transgenic breast cancer is independent of the urokinase receptor uPAR.

Almholt K, Lærum OD, Nielsen BS, Lund IK, Lund LR, Rømer J, Jögi A.

Clin Exp Metastasis. 2015 Aug;32(6):543-54. doi: 10.1007/s10585-015-9726-1. Epub 2015 Jun 4.

PMID:
26040548
11.

Growth pattern of colorectal liver metastasis as a marker of recurrence risk.

Eefsen RL, Vermeulen PB, Christensen IJ, Laerum OD, Mogensen MB, Rolff HC, Van den Eynden GG, Høyer-Hansen G, Osterlind K, Vainer B, Illemann M.

Clin Exp Metastasis. 2015 Apr;32(4):369-81. doi: 10.1007/s10585-015-9715-4. Epub 2015 Mar 31.

PMID:
25822899
12.

Tissue inhibitor of matrix metalloproteinase-1 expression in colorectal cancer liver metastases is associated with vascular structures.

Illemann M, Eefsen RH, Bird NC, Majeed A, Osterlind K, Laerum OD, Alpízar-Alpízar W, Lund IK, Høyer-Hansen G.

Mol Carcinog. 2016 Feb;55(2):193-208. doi: 10.1002/mc.22269. Epub 2015 Jan 15.

13.

Urokinase-type plasminogen activator receptor (uPAR) expression is associated with T-stage and survival in urothelial carcinoma of the bladder.

Dohn LH, Illemann M, Høyer-Hansen G, Christensen IJ, Hostmark J, Litlekalsoy J, von der Maase H, Pappot H, Laerum OD.

Urol Oncol. 2015 Apr;33(4):165.e15-24. doi: 10.1016/j.urolonc.2014.12.001. Epub 2015 Jan 6.

PMID:
25575713
14.

Expression of the Ly6/uPAR-domain proteins C4.4A and Haldisin in non-invasive and invasive skin lesions.

Kriegbaum MC, Clausen OP, Lærum OD, Ploug M.

J Histochem Cytochem. 2015 Feb;63(2):142-54. doi: 10.1369/0022155414563107. Epub 2014 Nov 20.

15.

Urokinase-type plasminogen activator receptor (uPAR) on tumor-associated macrophages is a marker of poor prognosis in colorectal cancer.

Illemann M, Laerum OD, Hasselby JP, Thurison T, Høyer-Hansen G, Nielsen HJ; Danish Study Group on Early Detection of Colorectal Cancer, Christensen IJ.

Cancer Med. 2014 Aug;3(4):855-64. doi: 10.1002/cam4.242. Epub 2014 May 30.

16.

«I'm a Norwegian doctor»--a quotation with a life of its own.

Lærum OD, Stien R, Hem E.

Tidsskr Nor Laegeforen. 2013 Dec 10;133(23-24):2490-2. doi: 10.4045/tidsskr.13.0907. English, Norwegian. No abstract available.

17.

Ly6/uPAR-related protein C4.4A as a marker of solid growth pattern and poor prognosis in lung adenocarcinoma.

Jacobsen B, Muley T, Meister M, Dienemann H, Christensen IJ, Santoni-Rugiu E, Lærum OD, Ploug M.

J Thorac Oncol. 2013 Feb;8(2):152-60. doi: 10.1097/JTO.0b013e318279d503.

18.

Time-dependent biological differences in molecular markers of high-grade urothelial cancer over 7 decades (ras proteins, pTEN, uPAR, PAI-1 and MMP-9).

Litlekalsoy J, Hostmark JG, Costea DE, Illemann M, Laerum OD.

Virchows Arch. 2012 Nov;461(5):541-51. doi: 10.1007/s00428-012-1323-y. Epub 2012 Oct 6.

PMID:
23052373
19.

Spontaneous metastasis in congenic mice with transgenic breast cancer is unaffected by plasminogen gene ablation.

Almholt K, Juncker-Jensen A, Lærum OD, Johnsen M, Rømer J, Lund LR.

Clin Exp Metastasis. 2013 Mar;30(3):277-88. doi: 10.1007/s10585-012-9534-9. Epub 2012 Sep 21.

PMID:
22996753
20.

Histopathological growth pattern, proteolysis and angiogenesis in chemonaive patients resected for multiple colorectal liver metastases.

Eefsen RL, Van den Eynden GG, Høyer-Hansen G, Brodt P, Laerum OD, Vermeulen PB, Christensen IJ, Wettergren A, Federspiel B, Willemoe GL, Vainer B, Osterlind K, Illemann M.

J Oncol. 2012;2012:907971. doi: 10.1155/2012/907971. Epub 2012 Aug 2.

21.

Plasmin-driven fibrinolysis facilitates skin tumor growth in a gender-dependent manner.

Hald A, Eickhardt H, Maerkedahl RB, Feldborg CW, Egerod KL, Engelholm LH, Laerum OD, Lund LR, Rønø B.

FASEB J. 2012 Nov;26(11):4445-57. doi: 10.1096/fj.12-208025. Epub 2012 Jul 19.

PMID:
22815383
22.

Long-term survival from adenocarcinoma of the esophagus after transthoracic and transhiatal esophagectomy.

Ovrebo KK, Lie SA, Laerum OD, Svanes K, Viste A.

World J Surg Oncol. 2012 Jun 30;10:130. doi: 10.1186/1477-7819-10-130.

23.

No effect of NGAL/lipocalin-2 on aggressiveness of cancer in the MMTV-PyMT/FVB/N mouse model for breast cancer.

Cramer EP, Glenthøj A, Häger M, Juncker-Jensen A, Engelholm LH, Santoni-Rugiu E, Lund LR, Laerum OD, Cowland JB, Borregaard N.

PLoS One. 2012;7(6):e39646. doi: 10.1371/journal.pone.0039646. Epub 2012 Jun 21.

24.

High-frequency ultrasonographic imaging of the gastrointestinal wall.

Ødegaard S, Nesje LB, Lærum OD, Kimmey MB.

Expert Rev Med Devices. 2012 May;9(3):263-73. doi: 10.1586/erd.12.6. Review.

PMID:
22702257
25.

Urokinase plasminogen activator receptor on invasive cancer cells: a prognostic factor in distal gastric adenocarcinoma.

Alpízar-Alpízar W, Christensen IJ, Santoni-Rugiu E, Skarstein A, Ovrebo K, Illemann M, Laerum OD.

Int J Cancer. 2012 Aug 15;131(4):E329-36. doi: 10.1002/ijc.26417. Epub 2011 Oct 20.

26.

Prognosis in adenocarcinomas of lower oesophagus, gastro-oesophageal junction and cardia evaluated by uPAR-immunohistochemistry.

Laerum OD, Ovrebo K, Skarstein A, Christensen IJ, Alpízar-Alpízar W, Helgeland L, Danø K, Nielsen BS, Illemann M.

Int J Cancer. 2012 Aug 1;131(3):558-69. doi: 10.1002/ijc.26382. Epub 2011 Oct 20.

27.

Expression of C4.4A in precursor lesions of pulmonary adenocarcinoma and squamous cell carcinoma.

Jacobsen B, Santoni-Rugiu E, Illemann M, Kriegbaum MC, Laerum OD, Ploug M.

Int J Cancer. 2012 Jun 1;130(11):2734-9. doi: 10.1002/ijc.26305. Epub 2011 Aug 24.

28.

Lithium differentially affects clock gene expression in serum-shocked NIH-3T3 cells.

Osland TM, Fernø J, Håvik B, Heuch I, Ruoff P, Lærum OD, Steen VM.

J Psychopharmacol. 2011 Jul;25(7):924-33. doi: 10.1177/0269881110379508. Epub 2010 Sep 13.

PMID:
20837565
29.

Circadian oscillators in eukaryotes.

Jolma IW, Laerum OD, Lillo C, Ruoff P.

Wiley Interdiscip Rev Syst Biol Med. 2010 Sep-Oct;2(5):533-549. doi: 10.1002/wsbm.81. Review.

PMID:
20836046
30.

αB-crystallin is elevated in highly infiltrative apoptosis-resistant glioblastoma cells.

Goplen D, Bougnaud S, Rajcevic U, Bøe SO, Skaftnesmo KO, Voges J, Enger PØ, Wang J, Tysnes BB, Laerum OD, Niclou S, Bjerkvig R.

Am J Pathol. 2010 Oct;177(4):1618-28. doi: 10.2353/ajpath.2010.090063. Epub 2010 Sep 2.

31.

Activation of Notch signaling in cardiomyocytes during post-infarction remodeling.

Øie E, Sandberg WJ, Ahmed MS, Yndestad A, Lærum OD, Attramadal H, Aukrust P, Eiken HG.

Scand Cardiovasc J. 2010 Dec;44(6):359-66. doi: 10.3109/14017431.2010.511256. Epub 2010 Aug 30.

PMID:
20799913
32.

Neutrophil gelatinase-associated lipocalin (NGAL/Lcn2) is upregulated in gastric mucosa infected with Helicobacter pylori.

Alpízar-Alpízar W, Laerum OD, Illemann M, Ramírez JA, Arias A, Malespín-Bendaña W, Ramírez V, Lund LR, Borregaard N, Nielsen BS.

Virchows Arch. 2009 Sep;455(3):225-33. doi: 10.1007/s00428-009-0825-8.

PMID:
19727808
33.

Urokinase plasminogen activator receptor is expressed in invasive cells in gastric carcinomas from high- and low-risk countries.

Alpízar-Alpízar W, Nielsen BS, Sierra R, Illemann M, Ramírez JA, Arias A, Durán S, Skarstein A, Ovrebo K, Lund LR, Laerum OD.

Int J Cancer. 2010 Jan 15;126(2):405-15. doi: 10.1002/ijc.24755.

34.

Induction of circadian rhythm in cultured human mesenchymal stem cells by serum shock and cAMP analogs in vitro.

Huang TS, Grodeland G, Sleire L, Wang MY, Kvalheim G, Laerum OD.

Chronobiol Int. 2009 Feb;26(2):242-57. doi: 10.1080/07420520902766025.

PMID:
19212839
35.

Two distinct expression patterns of urokinase, urokinase receptor and plasminogen activator inhibitor-1 in colon cancer liver metastases.

Illemann M, Bird N, Majeed A, Laerum OD, Lund LR, Danø K, Nielsen BS.

Int J Cancer. 2009 Apr 15;124(8):1860-70. doi: 10.1002/ijc.24166.

36.

Crohn's disease but not chronic ulcerative colitis induces the expression of PAI-1 in enteric neurons.

Laerum OD, Illemann M, Skarstein A, Helgeland L, Ovrebø K, Danø K, Nielsen BS.

Am J Gastroenterol. 2008 Sep;103(9):2350-8. doi: 10.1111/j.1572-0241.2008.01930.x.

PMID:
18844621
37.

Metastasis is strongly reduced by the matrix metalloproteinase inhibitor Galardin in the MMTV-PymT transgenic breast cancer model.

Almholt K, Juncker-Jensen A, Laerum OD, Danø K, Johnsen M, Lund LR, Rømer J.

Mol Cancer Ther. 2008 Sep;7(9):2758-67. doi: 10.1158/1535-7163.MCT-08-0251.

38.

Altered expression of the urokinase receptor homologue, C4.4A, in invasive areas of human esophageal squamous cell carcinoma.

Hansen LV, Laerum OD, Illemann M, Nielsen BS, Ploug M.

Int J Cancer. 2008 Feb 15;122(4):734-41.

39.

Circadian variations in clock gene expression of human bone marrow CD34+ cells.

Tsinkalovsky O, Smaaland R, Rosenlund B, Sothern RB, Hirt A, Steine S, Badiee A, Abrahamsen JF, Eiken HG, Laerum OD.

J Biol Rhythms. 2007 Apr;22(2):140-50.

PMID:
17440215
40.
41.

Zebrafish kidney marrow contains ABCG2-dependent side population cells exhibiting hematopoietic stem cell properties.

Tsinkalovsky O, Vik-Mo AO, Ferreira S, Laerum OD, Fjose A.

Differentiation. 2007 Mar;75(3):175-83. Epub 2006 Dec 11. Erratum in: Differentiation. 2007 Jul;75(6):575.

PMID:
17288542
42.

Protein disulfide isomerase expression is related to the invasive properties of malignant glioma.

Goplen D, Wang J, Enger PØ, Tysnes BB, Terzis AJ, Laerum OD, Bjerkvig R.

Cancer Res. 2006 Oct 15;66(20):9895-902.

43.

Circadian expression of clock genes in purified hematopoietic stem cells is developmentally regulated in mouse bone marrow.

Tsinkalovsky O, Filipski E, Rosenlund B, Sothern RB, Eiken HG, Wu MW, Claustrat B, Bayer J, Lévi F, Laerum OD.

Exp Hematol. 2006 Sep;34(9):1249-61.

PMID:
16939818
44.

HPV subtypes in cervical cancer biopsies between 1930 and 2004: detection using general primer pair PCR and sequencing.

Bertelsen BI, Kugarajh K, Skar R, Laerum OD.

Virchows Arch. 2006 Aug;449(2):141-7. Epub 2006 Jun 10.

PMID:
16767449
45.

MMP-9 is differentially expressed in primary human colorectal adenocarcinomas and their metastases.

Illemann M, Bird N, Majeed A, Sehested M, Laerum OD, Lund LR, Danø K, Nielsen BS.

Mol Cancer Res. 2006 May;4(5):293-302.

46.

Molecular analysis of the PI3K-AKT pathway in uterine cervical neoplasia: frequent PIK3CA amplification and AKT phosphorylation.

Bertelsen BI, Steine SJ, Sandvei R, Molven A, Laerum OD.

Int J Cancer. 2006 Apr 15;118(8):1877-83.

48.

Clock gene expression in purified mouse hematopoietic stem cells.

Tsinkalovsky O, Rosenlund B, Laerum OD, Eiken HG.

Exp Hematol. 2005 Jan;33(1):100-7.

PMID:
15661403
49.

[Cryobiology-- freeze preservation and storage of living cells and tissues].

Solberg S, Laerum OD.

Tidsskr Nor Laegeforen. 2004 Oct 21;124(20):2607-9. Norwegian.

50.

Brain tumour development and invasion. An interview with Ole Didrik Laerum.

Laerum OD.

Int J Dev Biol. 2004;48(5-6):497-508. No abstract available.

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