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Best matches for Läer S[au]:

Perinatal pharmacology. Allegaert K et al. Biomed Res Int. (2014)

NT-pro-B-type natriuretic peptide in infants and children: reference values based on combined data from four studies. Nir A et al. Pediatr Cardiol. (2009)

Optimizing the Clinical Use of Carvedilol in Liver Cirrhosis Using a Physiologically Based Pharmacokinetic Modeling Approach. Rasool MF et al. Eur J Drug Metab Pharmacokinet. (2017)

Search results

Items: 1 to 50 of 86

1.

Simultaneous Semi-Mechanistic Population Pharmacokinetic Modeling Analysis of Enalapril and Enalaprilat Serum and Urine Concentrations From Child Appropriate Orodispersible Minitablets.

Faisal M, Cawello W, Burckhardt BB, de Hoon J, Laer S; LENA Consortium.

Front Pediatr. 2019 Jul 9;7:281. doi: 10.3389/fped.2019.00281. eCollection 2019.

2.

Orodispersible minitablets of enalapril for use in children with heart failure (LENA): Rationale and protocol for a multicentre pharmacokinetic bridging study and follow-up safety study.

Bajcetic M, de Wildt SN, Dalinghaus M, Breitkreutz J, Klingmann I, Lagler FB, Keatley-Clarke A, Breur JM, Male C, Jovanovic I, Szatmári A, Ablonczy L, Burckhardt BB, Cawello W, Kleine K, Obarcanin E, Spatenkova L, Swoboda V, van der Meulen M, Wagner P, Walsh J, Läer S.

Contemp Clin Trials Commun. 2019 Jun 8;15:100393. doi: 10.1016/j.conctc.2019.100393. eCollection 2019 Sep.

3.

Pharmacotherapy in paediatric heart failure: a Delphi process.

Díez CC, Khalil F, Makowski N, Schwender H, Jovanovic I, Dalinghaus M, Walsh J, van der Meulen M, Bajcetic M, de Wildt SN, Läer S.

Cardiol Young. 2019 Jul;29(7):869-876. doi: 10.1017/S1047951119000660. Epub 2019 Jun 24.

PMID:
31230601
4.

[Pharmacokinetic and pharmacodynamic modelling in paediatric drug development with a focus on physiology-based pharmacokinetic simulations].

Läer S.

Z Evid Fortbild Qual Gesundhwes. 2019 May;141-142:66-73. doi: 10.1016/j.zefq.2019.03.003. Epub 2019 Mar 29. German.

PMID:
30935788
5.

Pharmacotherapeutic management of paediatric heart failure and ACE-I use patterns: a European survey.

Castro Díez C, Khalil F, Schwender H, Dalinghaus M, Jovanovic I, Makowski N, Male C, Bajcetic M, van der Meulen M, de Wildt SN, Ablonczy L, Szatmári A, Klingmann I, Walsh J, Läer S.

BMJ Paediatr Open. 2019 Jan 31;3(1):e000365. doi: 10.1136/bmjpo-2018-000365. eCollection 2019.

6.

Model-dependent pharmacokinetic analysis of enalapril administered to healthy adult volunteers using orodispersible minitablets for use in pediatrics.

Faisal M, Cawello W, Burckhardt BB, Laer S.

Drug Des Devel Ther. 2019 Jan 25;13:481-490. doi: 10.2147/DDDT.S188417. eCollection 2019.

7.

LC-MS/MS method for screening of intoxication and drug adherence of angiotensin-converting enzyme inhibitors in plasma.

Ali M, Läer S, Burckhardt BB.

Bioanalysis. 2018 Nov 6. doi: 10.4155/bio-2018-0200. [Epub ahead of print]

PMID:
30412687
8.

Ethnic differences in hypertension prevalence and contributing determinants - the HELIUS study.

van Laer SD, Snijder MB, Agyemang C, Peters RJ, van den Born BH.

Eur J Prev Cardiol. 2018 Dec;25(18):1914-1922. doi: 10.1177/2047487318803241. Epub 2018 Oct 9.

PMID:
30296837
9.

Pharmaceutical care of an adolescent with type 1 diabetes.

Obarcanin E, Deters MA, Nemitz V, Läer S.

Med Monatsschr Pharm. 2016 Nov;39(11):483-7. English, German.

PMID:
29956527
10.

Diabetes Stewardship – Pharmaceutical care of adolescents with type 1 diabetes mellitus provided by community pharmacists.

Deters MA, Läer S, Hasanbegović S, Nemitz V, Müller P, Krüger M, Schwender H, Obarcanin E.

Med Monatsschr Pharm. 2016 Nov;39(11):477-82. English, German.

PMID:
29956526
11.

Optimizing the Clinical Use of Carvedilol in Liver Cirrhosis Using a Physiologically Based Pharmacokinetic Modeling Approach.

Rasool MF, Khalil F, Läer S.

Eur J Drug Metab Pharmacokinet. 2017 Jun;42(3):383-396. doi: 10.1007/s13318-016-0353-2.

PMID:
27313074
13.

Tailored Assays for Pharmacokinetic and Pharmacodynamic Investigations of Aliskiren and Enalapril in Children: An Application in Serum, Urine, and Saliva.

Burckhardt BB, Tins J, Ramusovic S, Läer S.

J Pediatr Pharmacol Ther. 2015 Nov-Dec;20(6):431-52. doi: 10.5863/1551-6776-20.6.431.

15.

Current and remitted depression and anxiety disorders as risk factors for medication nonadherence.

Bet PM, Penninx BW, van Laer SD, Hoogendijk WJ, Hugtenburg JG.

J Clin Psychiatry. 2015 Sep;76(9):e1114-21. doi: 10.4088/JCP.14m09001.

PMID:
26455675
16.

Pharmaceutical care of adolescents with diabetes mellitus type 1: the DIADEMA study, a randomized controlled trial.

Obarcanin E, Krüger M, Müller P, Nemitz V, Schwender H, Hasanbegovic S, Kalajdzisalihovic S, Läer S.

Int J Clin Pharm. 2015 Oct;37(5):790-8. doi: 10.1007/s11096-015-0122-3. Epub 2015 Apr 28.

PMID:
25917376
18.

[PHARMAGRIPS: structured pharmaceutical counseling in the self-medication of the common cold. A randomised controlled study (RCT)].

Laven A, Schäfer J, Läer S.

Med Monatsschr Pharm. 2014 Jun;37(6):209-20. German.

PMID:
25051811
19.

Perinatal pharmacology.

Allegaert K, Fanos V, van den Anker JN, Laër S.

Biomed Res Int. 2014;2014:101620. doi: 10.1155/2014/101620. Epub 2014 Apr 13. No abstract available.

20.

[Dextromethorphan abuse in adolescents: what can the pharmacists do?].

Müller S, Jaffan L, Kloiber E, Läer S.

Med Monatsschr Pharm. 2014 Mar;37(3):95-100. German.

PMID:
24741849
21.
22.

Pharmacokinetics of intravenous amiodarone in children.

Ramusovic S, Läer S, Meibohm B, Lagler FB, Paul T.

Arch Dis Child. 2013 Dec;98(12):989-93. doi: 10.1136/archdischild-2013-304483. Epub 2013 Sep 19.

PMID:
24051016
23.

[Pharmacist's requirements for evidence-based self-medication guidelines].

Laven A, Läer S.

Med Monatsschr Pharm. 2013 Mar;36(3):102-10. German.

PMID:
23573693
24.

Response to "Physiologically based pharmacokinetic modeling at the extremes of age".

Della Casa Alberighi O, Barrett JS, Läer S, Meibohm B.

Clin Pharmacol Ther. 2013 Feb;93(2):149. doi: 10.1038/clpt.2012.200. Epub 2012 Nov 28. No abstract available.

PMID:
23187875
25.

Physiologically based pharmacokinetic (PBPK) modeling in children.

Barrett JS, Della Casa Alberighi O, Läer S, Meibohm B.

Clin Pharmacol Ther. 2012 Jul;92(1):40-9. doi: 10.1038/clpt.2012.64. Epub 2012 Jun 6. Review.

PMID:
22669290
26.

Treatment for paediatric low cardiac output syndrome: results from the European EuLoCOS-Paed survey.

Vogt W, Läer S.

Arch Dis Child. 2011 Dec;96(12):1180-6. doi: 10.1136/archdischild-2011-300370. Epub 2011 Oct 27.

PMID:
22034494
27.

Determination of enalapril and enalaprilat in small human serum quantities for pediatric trials by HPLC-tandem mass spectrometry.

Ramusovic S, Thielking G, Läer S.

Biomed Chromatogr. 2012 Jun;26(6):697-702. doi: 10.1002/bmc.1716. Epub 2011 Sep 23.

PMID:
21953651
28.

Study design and simulation approach.

Läer S, Meibohm B.

Handb Exp Pharmacol. 2011;205:125-48. doi: 10.1007/978-3-642-20195-0_6.

PMID:
21882109
29.

Prevention for pediatric low cardiac output syndrome: results from the European survey EuLoCOS-Paed.

Vogt W, Läer S.

Paediatr Anaesth. 2011 Dec;21(12):1176-84. doi: 10.1111/j.1460-9592.2011.03683.x. Epub 2011 Aug 18.

PMID:
21851475
30.

Physiologically based pharmacokinetic modeling: methodology, applications, and limitations with a focus on its role in pediatric drug development.

Khalil F, Läer S.

J Biomed Biotechnol. 2011;2011:907461. doi: 10.1155/2011/907461. Epub 2011 Jun 1. Review.

31.

Pediatric cardiovascular drug development and research: integration of modeling and simulation as one future direction.

Läer S.

J Cardiovasc Pharmacol. 2011 Sep;58(3):217-27. doi: 10.1097/FJC.0b013e31822233c1. Review.

PMID:
21654330
32.

Drug use patterns for the prevention of paediatric low cardiac output syndrome in Europe.

Vogt W, Läer S.

Intensive Care Med. 2011 Aug;37(8):1390-1. doi: 10.1007/s00134-011-2266-5. Epub 2011 Jun 7. No abstract available.

33.

[Adverse drug reactions in children].

Jaffan L, Läer S.

Ther Umsch. 2011 Jan;68(1):34-40. doi: 10.1024/0040-5930/a000117. German.

PMID:
21184392
34.

[The ideal dosage form for clinical study. Bosentan in pediatric patients].

Ramusovic S, Läer S, Breitkreutz J.

Pharm Unserer Zeit. 2010 Nov;39(6):454-8. doi: 10.1002/pauz.201000391. Review. German. No abstract available.

PMID:
20967934
35.

Primary HHV 6 infection after liver transplantation with acute graft rejection and multi-organ failure: successful treatment with a 2.5-fold dose of cidofovir and reduction of immunosuppression.

Dohna-Schwake C, Fiedler M, Gierenz N, Gerner P, Ballauf A, Breddemann A, Läer S, Baba HA, Hoyer PF.

Pediatr Transplant. 2011 Sep;15(6):E126-9. doi: 10.1111/j.1399-3046.2010.01310.x. Epub 2010 Mar 17.

PMID:
20331520
36.

Pharmacogenomic adaptation of antiretroviral therapy: overcoming the failure of lopinavir in an African infant with CYP2D6 ultrarapid metabolism.

Gorny M, Röhm S, Läer S, Morali N, Niehues T.

Eur J Clin Pharmacol. 2010 Jan;66(1):107-8. doi: 10.1007/s00228-009-0753-1. Epub 2009 Nov 20. No abstract available.

PMID:
19936726
37.

The in silico child: using simulation to guide pediatric drug development and manage pediatric pharmacotherapy.

Läer S, Barrett JS, Meibohm B.

J Clin Pharmacol. 2009 Aug;49(8):889-904. doi: 10.1177/0091270009337513. Epub 2009 Jun 16. Review.

PMID:
19531673
38.

Beta-blockers for congestive heart failure in children.

Frobel AK, Hulpke-Wette M, Schmidt KG, Läer S.

Cochrane Database Syst Rev. 2009 Jan 21;(1):CD007037. doi: 10.1002/14651858.CD007037.pub2. Review. Update in: Cochrane Database Syst Rev. 2016;1:CD007037.

PMID:
19160314
39.

[Particularities of pharmacotherapy in children. Is there a metamorphosis of "therapeutic orphans"?].

Vogt W, Frobel AK, Läer S.

Pharm Unserer Zeit. 2009;38(1):22-9. doi: 10.1002/pauz.200800292. Review. German. No abstract available.

PMID:
19132671
40.

[Computer simulations to support drug therapy in children].

Breddemann A, Läer S.

Med Monatsschr Pharm. 2008 Nov;31(11):429-33. Review. German.

PMID:
19055162
41.

Phosphorylation of phospholamban and troponin I through 5-HT4 receptors in the isolated human atrium.

Gergs U, Neumann J, Simm A, Silber RE, Remmers FO, Läer S.

Naunyn Schmiedebergs Arch Pharmacol. 2009 Apr;379(4):349-59. doi: 10.1007/s00210-008-0371-y. Epub 2008 Nov 11.

PMID:
19002436
42.

NT-pro-B-type natriuretic peptide in infants and children: reference values based on combined data from four studies.

Nir A, Lindinger A, Rauh M, Bar-Oz B, Laer S, Schwachtgen L, Koch A, Falkenberg J, Mir TS.

Pediatr Cardiol. 2009 Jan;30(1):3-8. doi: 10.1007/s00246-008-9258-4. Epub 2008 Jul 4. Review.

PMID:
18600369
43.

Evaluation of the users value of salts against apple scab and powdery mildew for the integrated fruit production.

Creemers P, Van Laer S, Van Mechelen A, Vorstermans B, Hauke K.

Commun Agric Appl Biol Sci. 2007;72(4):917-23.

PMID:
18396829
44.

Off-label drug use among hospitalised children: identifying areas with the highest need for research.

Hsien L, Breddemann A, Frobel AK, Heusch A, Schmidt KG, Läer S.

Pharm World Sci. 2008 Oct;30(5):497-502. doi: 10.1007/s11096-008-9193-8. Epub 2008 Jan 26.

PMID:
18219585
45.

Quantification of cidofovir in human serum by LC-MS/MS for children.

Breddemann A, Hsien L, Tot E, Läer S.

J Chromatogr B Analyt Technol Biomed Life Sci. 2008 Jan 1;861(1):1-9. Epub 2007 Dec 4.

PMID:
18083075
46.

Population pharmacokinetics and dose simulation of carvedilol in paediatric patients with congestive heart failure.

Albers S, Meibohm B, Mir TS, Läer S.

Br J Clin Pharmacol. 2008 Apr;65(4):511-22. Epub 2007 Nov 8.

47.

Case report: severe gastrointestinal inflammation and persistent HHV-6B infection in a paediatric cancer patient.

Breddemann A, Läer S, Schmidt KG, Harjes M, Adam R, Ludwig A, Niehues T, Schneider DT.

Herpes. 2007 Sep;14(2):41-4.

PMID:
17939902
48.

Effect of Carvedilol on QT Duration in Paediatric Patients with Congestive Heart Failure.

Mir TS, Läer S, Eiselt M, Falkenberg J, Gottschalk U, Weil J.

Clin Drug Investig. 2004;24(1):9-15.

PMID:
17516686
49.

Brown spot control on pear: infection models versus the inoculum pressure in Belgium.

Van Laer S, Vorstermans B, Hauke K, Creemers P.

Commun Agric Appl Biol Sci. 2006;71(3 Pt A):839-47.

PMID:
17390829
50.

Botrytis infection warnings in strawberry: reduced enhanced chemical control.

Van Laer S, Hauke K, Meesters P, Creemers P.

Commun Agric Appl Biol Sci. 2005;70(3):61-71.

PMID:
16637160

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