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Items: 12


Correction of diverse muscular dystrophy mutations in human engineered heart muscle by single-site genome editing.

Long C, Li H, Tiburcy M, Rodriguez-Caycedo C, Kyrychenko V, Zhou H, Zhang Y, Min YL, Shelton JM, Mammen PPA, Liaw NY, Zimmermann WH, Bassel-Duby R, Schneider JW, Olson EN.

Sci Adv. 2018 Jan 31;4(1):eaap9004. doi: 10.1126/sciadv.aap9004. eCollection 2018 Jan.


Down Syndrome Critical Region 1 Gene, Rcan1, Helps Maintain a More Fused Mitochondrial Network.

Parra V, Altamirano F, Hernández-Fuentes CP, Tong D, Kyrychenko V, Rotter D, Pedrozo Z, Hill JA, Eisner V, Lavandero S, Schneider JW, Rothermel BA.

Circ Res. 2018 Mar 16;122(6):e20-e33. doi: 10.1161/CIRCRESAHA.117.311522. Epub 2018 Jan 23.


Deficit in PINK1/PARKIN-mediated mitochondrial autophagy at late stages of dystrophic cardiomyopathy.

Kang C, Badr MA, Kyrychenko V, Eskelinen EL, Shirokova N.

Cardiovasc Res. 2018 Jan 1;114(1):90-102. doi: 10.1093/cvr/cvx201.


Functional correction of dystrophin actin binding domain mutations by genome editing.

Kyrychenko V, Kyrychenko S, Tiburcy M, Shelton JM, Long C, Schneider JW, Zimmermann WH, Bassel-Duby R, Olson EN.

JCI Insight. 2017 Sep 21;2(18). pii: 95918. doi: 10.1172/jci.insight.95918. [Epub ahead of print]


Small Fractions of Muscular Dystrophy Embryonic Stem Cells Yield Severe Cardiac and Skeletal Muscle Defects in Adult Mouse Chimeras.

Gonzalez JP, Kyrychenko S, Kyrychenko V, Schneider JS, Granier CJ, Himelman E, Lahey KC, Zhao Q, Yehia G, Tao YX, Bhaumik M, Shirokova N, Fraidenraich D.

Stem Cells. 2017 Mar;35(3):597-610. doi: 10.1002/stem.2518. Epub 2016 Nov 2.


Inhibition of class I histone deacetylases blunts cardiac hypertrophy through TSC2-dependent mTOR repression.

Morales CR, Li DL, Pedrozo Z, May HI, Jiang N, Kyrychenko V, Cho GW, Kim SY, Wang ZV, Rotter D, Rothermel BA, Schneider JW, Lavandero S, Gillette TG, Hill JA.

Sci Signal. 2016 Apr 5;9(422):ra34. doi: 10.1126/scisignal.aad5736.


Doxorubicin Blocks Cardiomyocyte Autophagic Flux by Inhibiting Lysosome Acidification.

Li DL, Wang ZV, Ding G, Tan W, Luo X, Criollo A, Xie M, Jiang N, May H, Kyrychenko V, Schneider JW, Gillette TG, Hill JA.

Circulation. 2016 Apr 26;133(17):1668-87. doi: 10.1161/CIRCULATIONAHA.115.017443. Epub 2016 Mar 16.


Pivotal role of miR-448 in the development of ROS-induced cardiomyopathy.

Kyrychenko S, Kyrychenko V, Badr MA, Ikeda Y, Sadoshima J, Shirokova N.

Cardiovasc Res. 2015 Dec 1;108(3):324-34. doi: 10.1093/cvr/cvv238. Epub 2015 Oct 26.


Mitochondrial dysfunctions during progression of dystrophic cardiomyopathy.

Kyrychenko V, Poláková E, Janíček R, Shirokova N.

Cell Calcium. 2015 Aug;58(2):186-95. doi: 10.1016/j.ceca.2015.04.006. Epub 2015 Apr 30.


Knockdown of PSMB7 induces autophagy in cardiomyocyte cultures: possible role in endoplasmic reticulum stress.

Kyrychenko VO, Nagibin VS, Tumanovska LV, Pashevin DO, Gurianova VL, Moibenko AA, Dosenko VE, Klionsky DJ.

Pathobiology. 2014;81(1):8-14. doi: 10.1159/000350704. Epub 2013 Aug 21.


[Effects of ubiquitin gene silencing in anoxia-reoxygenation of cultured cardiomyocytes].

Kyrychenko VO, Nahibin VS, Tumanovs'ka LV, Dosenko VIe, Rybal'chenko VK, Moĭbenko OO.

Fiziol Zh. 2010;56(4):37-46. Ukrainian.


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