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Items: 1 to 50 of 118

1.

Wide phenotypic variability in RSPH9-associated primary ciliary dyskinesia: review of a case-series from Cyprus.

Yiallouros PK, Kouis P, Pirpa P, Michailidou K, Loizidou MA, Potamiti L, Kalyva M, Koutras G, Kyriacou K, Hadjisavvas A.

J Thorac Dis. 2019 May;11(5):2067-2075. doi: 10.21037/jtd.2019.04.71.

2.

The spectrum of BRCA1 and BRCA2 pathogenic sequence variants in Middle Eastern, North African, and South European countries.

Laitman Y, Friebel TM, Yannoukakos D, Fostira F, Konstantopoulou I, Figlioli G, Bonanni B, Manoukian S, Zuradelli M, Tondini C, Pasini B, Peterlongo P, Plaseska-Karanfilska D, Jakimovska M, Majidzadeh K, Zarinfam S, Loizidou MA, Hadjisavvas A, Michailidou K, Kyriacou K, Behar DM, Molho RB, Ganz P, James P, Parsons MT, Sallam A, Olopade OI, Seth A, Chenevix-Trench G, Leslie G, McGuffog L, Marafie MJ, Megarbane A, Al-Mulla F, Rebbeck TR, Friedman E.

Hum Mutat. 2019 Jun 17. doi: 10.1002/humu.23842. [Epub ahead of print]

PMID:
31209999
3.

Cost-effectiveness analysis of three algorithms for diagnosing primary ciliary dyskinesia: a simulation study.

Kouis P, Papatheodorou SI, Middleton N, Giallouros G, Kyriacou K, Cohen JT, Evans JS, Yiallouros PK.

Orphanet J Rare Dis. 2019 Jun 13;14(1):142. doi: 10.1186/s13023-019-1116-3.

4.

Assessment of melanoma candidate genes in a meta-analysis of 16 534 melanoma cases.

Ntritsos G, Dimou N, Kypreou K, Stefanaki I, Loizidou MA, Hadjisavvas A, Kyriacou K; Melanoma Meta-Analysis Consortium, MacGregor S, Law MH, Iles MM, Stratigos AJ, Evangelou E.

J Eur Acad Dermatol Venereol. 2019 Oct;33(10):e369-e370. doi: 10.1111/jdv.15662. Epub 2019 May 26. No abstract available.

PMID:
31071243
5.

Clinical course and outcome after kidney transplantation in patients with C3 glomerulonephritis due to CFHR5 nephropathy.

Frangou E, Varnavidou-Nicolaidou A, Petousis P, Soloukides A, Theophanous E, Savva I, Michael N, Toumasi E, Georgiou D, Stylianou G, Mean R, Anastasiadou N, Athanasiou Y, Zavros M, Kyriacou K, Deltas C, Hadjianastassiou V.

Nephrol Dial Transplant. 2019 Oct 1;34(10):1780-1788. doi: 10.1093/ndt/gfz021.

PMID:
30844074
6.

Improved cellular uptake of perfluorocarbon nanoparticles for in vivo murine cardiac 19F MRS/MRI and temporal tracking of progenitor cells.

Constantinides C, McNeill E, Carnicer R, Al Haj Zen A, Sainz-Urruela R, Shaw A, Patel J, Swider E, Alonaizan R, Potamiti L, Hadjisavvas A, Padilla-Parra S, Kyriacou K, Srinivas M, Carr CA.

Nanomedicine. 2019 Jun;18:391-401. doi: 10.1016/j.nano.2018.10.014. Epub 2018 Nov 16.

PMID:
30448526
7.

Omega-3 Fatty Acids Supplementation: Therapeutic Potential in a Mouse Model of Stargardt Disease.

Prokopiou E, Kolovos P, Kalogerou M, Neokleous A, Nicolaou O, Sokratous K, Kyriacou K, Georgiou T.

Invest Ophthalmol Vis Sci. 2018 Jun 1;59(7):2757-2767. doi: 10.1167/iovs.17-23523.

PMID:
29860462
8.

Evaluation of nipple aspirate fluid as a diagnostic tool for early detection of breast cancer.

Shaheed SU, Tait C, Kyriacou K, Linforth R, Salhab M, Sutton C.

Clin Proteomics. 2018 Jan 11;15:3. doi: 10.1186/s12014-017-9179-4. eCollection 2018. Review.

9.

The effect of l-Arginine on Ciliary Beat Frequency in PCD patients, non-PCD respiratory patients and healthy controls.

Kouis P, Hadjisavvas A, Middleton N, Papatheodorou SI, Kyriacou K, Yiallouros PK.

Pulm Pharmacol Ther. 2018 Feb;48:15-21. doi: 10.1016/j.pupt.2017.10.010. Epub 2017 Oct 19.

PMID:
29056509
10.

Editorial.

Kyriacou K, Yiallouros P.

Ultrastruct Pathol. 2017 Nov-Dec;41(6):370-372. doi: 10.1080/01913123.2017.1367361. Epub 2017 Sep 5. No abstract available.

PMID:
28872924
11.

Pharmacological Stimulation of Phagocytosis Enhances Amyloid Plaque Clearance; Evidence from a Transgenic Mouse Model of ATTR Neuropathy.

Fella E, Sokratous K, Papacharalambous R, Kyriacou K, Phillips J, Sanderson S, Panayiotou E, Kyriakides T.

Front Mol Neurosci. 2017 May 10;10:138. doi: 10.3389/fnmol.2017.00138. eCollection 2017.

12.

Nipple aspirate fluid-A liquid biopsy for diagnosing breast health.

Shaheed SU, Tait C, Kyriacou K, Mullarkey J, Burrill W, Patterson LH, Linforth R, Salhab M, Sutton CW.

Proteomics Clin Appl. 2017 Sep;11(9-10). doi: 10.1002/prca.201700015. Epub 2017 Jun 26.

13.

Oculo-Dento-Digital Dysplasia (ODDD) Due to a GJA1 Mutation: Report of a Case with Emphasis on Dental Manifestations.

Hadjichristou C, Christophidou-Anastasiadou V, Bakopoulou A, Tanteles GA, Loizidou MA, Kyriacou K, Hadjisavvas A, Michalakis K, Pissiotis A, Koidis P.

Int J Prosthodont. 2017 May/June;30(3):280–285. doi: 10.11607/ijp.5130. Epub 2017 Mar 20.

PMID:
28319210
14.

Mouse Stbd1 is N-myristoylated and affects ER-mitochondria association and mitochondrial morphology.

Demetriadou A, Morales-Sanfrutos J, Nearchou M, Baba O, Kyriacou K, Tate EW, Drousiotou A, Petrou PP.

J Cell Sci. 2017 Mar 1;130(5):903-915. doi: 10.1242/jcs.195263. Epub 2017 Jan 30.

15.

Prevalence of primary ciliary dyskinesia in consecutive referrals of suspect cases and the transmission electron microscopy detection rate: a systematic review and meta-analysis.

Kouis P, Yiallouros PK, Middleton N, Evans JS, Kyriacou K, Papatheodorou SI.

Pediatr Res. 2017 Mar;81(3):398-405. doi: 10.1038/pr.2016.263. Epub 2016 Dec 9. Review.

PMID:
27935903
16.

BRCA1 and BRCA2 mutation testing in Cyprus; a population based study.

Loizidou MA, Hadjisavvas A, Pirpa P, Spanou E, Delikurt T, Tanteles GA, Daniel M, Kountourakis P, Malas S, Ioannidis G, Zouvani I, Kakouri E, Papamichael D, Marcou Y, Anastasiadou V, Kyriacou K.

Clin Genet. 2017 Apr;91(4):611-615. doi: 10.1111/cge.12886. Epub 2016 Nov 23.

PMID:
27882536
17.

Biomarkers of systemic lupus erythematosus identified using mass spectrometry-based proteomics: a systematic review.

Nicolaou O, Kousios A, Hadjisavvas A, Lauwerys B, Sokratous K, Kyriacou K.

J Cell Mol Med. 2017 May;21(5):993-1012. doi: 10.1111/jcmm.13031. Epub 2016 Nov 23. Review.

18.

Mediterranean diet-gene interactions: A targeted metabolomics study in Greek-Cypriot women.

Kakkoura MG, Sokratous K, Demetriou CA, Loizidou MA, Loucaides G, Kakouri E, Hadjisavvas A, Kyriacou K.

Mol Nutr Food Res. 2017 Apr;61(4). doi: 10.1002/mnfr.201600558. Epub 2017 Jan 25.

PMID:
27860207
19.

Association between Echinococcus granulosus infection and cancer risk - a pilot study in Cyprus.

Oikonomopoulou K, Yu H, Wang Z, Vasiliou SK, Brinc D, Christofi G, Theodorou M, Pavlou P, Hadjisavvas A, Demetriou CA, Kyriacou K, Diamandis EP.

Clin Chem Lab Med. 2016 Dec 1;54(12):1955-1961. doi: 10.1515/cclm-2016-0125.

PMID:
27327131
20.

Marine and terrestrial foods as a source of brain-selective nutrients for early modern humans in the southwestern Cape, South Africa.

Kyriacou K, Blackhurst DM, Parkington JE, Marais AD.

J Hum Evol. 2016 Aug;97:86-96. doi: 10.1016/j.jhevol.2016.04.009. Epub 2016 Jun 23.

PMID:
27457547
21.

Fanconi anemia-D1 due to homozygosity for the BRCA2 gene Cypriot founder mutation: A case report.

Loizidou MA, Hadjisavvas A, Tanteles GA, Spanou-Aristidou E, Kyriacou K, Christophidou-Anastasiadou V.

Oncol Lett. 2016 Jan;11(1):471-473. Epub 2015 Nov 2.

22.

The synergistic effect between the Mediterranean diet and GSTP1 or NAT2 SNPs decreases breast cancer risk in Greek-Cypriot women.

Kakkoura MG, Loizidou MA, Demetriou CA, Loucaides G, Daniel M, Kyriacou K, Hadjisavvas A.

Eur J Nutr. 2017 Mar;56(2):545-555. doi: 10.1007/s00394-015-1099-3. Epub 2015 Nov 16.

PMID:
26572891
23.

MnSOD and CAT polymorphisms modulate the effect of the Mediterranean diet on breast cancer risk among Greek-Cypriot women.

Kakkoura MG, Demetriou CA, Loizidou MA, Loucaides G, Neophytou I, Malas S, Kyriacou K, Hadjisavvas A.

Eur J Nutr. 2016 Jun;55(4):1535-44. doi: 10.1007/s00394-015-0971-5. Epub 2015 Jul 1.

PMID:
26130326
24.

Oxaliplatin-induced neurotoxicity is mediated through gap junction channels and hemichannels and can be prevented by octanol.

Kagiava A, Theophilidis G, Sargiannidou I, Kyriacou K, Kleopa KA.

Neuropharmacology. 2015 Oct;97:289-305. doi: 10.1016/j.neuropharm.2015.05.021. Epub 2015 Jun 1.

PMID:
26044641
25.

Clinical features of primary ciliary dyskinesia in Cyprus with emphasis on lobectomized patients.

Yiallouros PK, Kouis P, Middleton N, Nearchou M, Adamidi T, Georgiou A, Eleftheriou A, Ioannou P, Hadjisavvas A, Kyriacou K.

Respir Med. 2015 Mar;109(3):347-56. doi: 10.1016/j.rmed.2015.01.015. Epub 2015 Jan 31.

26.

Biological embedding of early-life exposures and disease risk in humans: a role for DNA methylation.

Demetriou CA, van Veldhoven K, Relton C, Stringhini S, Kyriacou K, Vineis P.

Eur J Clin Invest. 2015 Mar;45(3):303-32. doi: 10.1111/eci.12406. Review.

PMID:
25645488
27.

Single-nucleotide polymorphisms in one-carbon metabolism genes, Mediterranean diet and breast cancer risk: a case-control study in the Greek-Cypriot female population.

Kakkoura MG, Demetriou CA, Loizidou MA, Loucaides G, Neophytou I, Marcou Y, Hadjisavvas A, Kyriacou K.

Genes Nutr. 2015 Mar;10(2):453. doi: 10.1007/s12263-015-0453-7. Epub 2015 Jan 21.

28.

Nutrition, modernity and the archaeological record: coastal resources and nutrition among Middle Stone Age hunter-gatherers on the Western Cape coast of South Africa.

Kyriacou K, Parkington JE, Marais AD, Braun DR.

J Hum Evol. 2014 Dec;77:64-73. doi: 10.1016/j.jhevol.2014.02.024. Epub 2014 Oct 16.

PMID:
25440132
29.

The mutational spectrum of Lynch syndrome in cyprus.

Loizidou MA, Neophytou I, Papamichael D, Kountourakis P, Vassiliou V, Marcou Y, Kakouri E, Ioannidis G, Philippou C, Spanou E, Tanteles GA, Anastasiadou V, Hadjisavvas A, Kyriacou K.

PLoS One. 2014 Aug 18;9(8):e105501. doi: 10.1371/journal.pone.0105501. eCollection 2014.

30.

The role of ubiquitin-binding domains in human pathophysiology.

Sokratous K, Hadjisavvas A, Diamandis EP, Kyriacou K.

Crit Rev Clin Lab Sci. 2014 Oct;51(5):280-90. doi: 10.3109/10408363.2014.915287. Epub 2014 Jun 5. Review.

PMID:
24901807
31.

The BRCA1 variant p.Ser36Tyr abrogates BRCA1 protein function and potentially confers a moderate risk of breast cancer.

Christou CM, Hadjisavvas A, Kyratzi M, Flouri C, Neophytou I, Anastasiadou V, Loizidou MA, Kyriacou K.

PLoS One. 2014 Apr 2;9(4):e93400. doi: 10.1371/journal.pone.0093400. eCollection 2014.

32.

The bifacial role of helminths in cancer: involvement of immune and non-immune mechanisms.

Oikonomopoulou K, Brinc D, Hadjisavvas A, Christofi G, Kyriacou K, Diamandis EP.

Crit Rev Clin Lab Sci. 2014 Jun;51(3):138-48. doi: 10.3109/10408363.2014.886180. Epub 2014 Mar 4. Review.

PMID:
24588712
33.

Methylome analysis and epigenetic changes associated with menarcheal age.

Demetriou CA, Chen J, Polidoro S, van Veldhoven K, Cuenin C, Campanella G, Brennan K, Clavel-Chapelon F, Dossus L, Kvaskoff M, Drogan D, Boeing H, Kaaks R, Risch A, Trichopoulos D, Lagiou P, Masala G, Sieri S, Tumino R, Panico S, Quirós JR, Sánchez Perez MJ, Amiano P, Huerta Castaño JM, Ardanaz E, Onland-Moret C, Peeters P, Khaw KT, Wareham N, Key TJ, Travis RC, Romieu I, Gallo V, Gunter M, Herceg Z, Kyriacou K, Riboli E, Flanagan JM, Vineis P.

PLoS One. 2013 Nov 20;8(11):e79391. doi: 10.1371/journal.pone.0079391. eCollection 2013.

34.

Identification of stage-specific breast markers using quantitative proteomics.

Shaheed SU, Rustogi N, Scally A, Wilson J, Thygesen H, Loizidou MA, Hadjisavvas A, Hanby A, Speirs V, Loadman P, Linforth R, Kyriacou K, Sutton CW.

J Proteome Res. 2013 Dec 6;12(12):5696-708. doi: 10.1021/pr400662k. Epub 2013 Oct 29.

PMID:
24106833
35.

Infection and cancer: revaluation of the hygiene hypothesis.

Oikonomopoulou K, Brinc D, Kyriacou K, Diamandis EP.

Clin Cancer Res. 2013 Jun 1;19(11):2834-41. doi: 10.1158/1078-0432.CCR-12-3661. Epub 2013 Mar 27. Review.

36.

BRCA1 and Its Network of Interacting Partners.

Christou CM, Kyriacou K.

Biology (Basel). 2013 Jan 2;2(1):40-63. doi: 10.3390/biology2010040.

37.

Proteomic profiling of breast tissue collagens and site-specific characterization of hydroxyproline residues of collagen alpha-1-(I).

Montgomery H, Rustogi N, Hadjisavvas A, Tanaka K, Kyriacou K, Sutton CW.

J Proteome Res. 2012 Dec 7;11(12):5890-902. doi: 10.1021/pr300656r. Epub 2012 Nov 14.

PMID:
23110299
38.

Early treatment with glucocorticoids or cyclophosphamide retains the slit diaphragm proteins nephrin and podocin in experimental lupus nephritis.

Moysiadis DK, Perysinaki GS, Bertsias G, Stratakis S, Kyriacou K, Nakopoulou L, Boumpas DT, Daphnis E.

Lupus. 2012 Oct;21(11):1196-207. doi: 10.1177/0961203312451784. Epub 2012 Jul 5. Erratum in: Lupus. 2013 Jul;22(8):868.

PMID:
22767414
39.

The mediterranean dietary pattern and breast cancer risk in Greek-Cypriot women: a case-control study.

Demetriou CA, Hadjisavvas A, Loizidou MA, Loucaides G, Neophytou I, Sieri S, Kakouri E, Middleton N, Vineis P, Kyriacou K.

BMC Cancer. 2012 Mar 23;12:113. doi: 10.1186/1471-2407-12-113.

40.

Human muscle-derived stem cells. Effectiveness in animal models of faecal incontinence. Research scheduling.

Mongardini M, Lisi A, Giofrè M, Ledda M, Grimaldi S, Scarnò M, Trucchia A, Kyriacou KA, Badiali D, Custureri F.

G Chir. 2011 Aug-Sep;32(8-9):357-60. Erratum in: G Chir. 2011 Nov-Dec;32(11-12):506. Kyriacou, A K [corrected to Kyriacou, K A].

PMID:
22018255
41.

Familial C3 glomerulopathy associated with CFHR5 mutations: clinical characteristics of 91 patients in 16 pedigrees.

Athanasiou Y, Voskarides K, Gale DP, Damianou L, Patsias C, Zavros M, Maxwell PH, Cook HT, Demosthenous P, Hadjisavvas A, Kyriacou K, Zouvani I, Pierides A, Deltas C.

Clin J Am Soc Nephrol. 2011 Jun;6(6):1436-46. doi: 10.2215/CJN.09541010. Epub 2011 May 12.

42.

Podocyte main slit diaphragm proteins, nephrin and podocin, are affected at early stages of lupus nephritis and correlate with disease histology.

Perysinaki GS, Moysiadis DK, Bertsias G, Giannopoulou I, Kyriacou K, Nakopoulou L, Boumpas DT, Daphnis E.

Lupus. 2011 Jul;20(8):781-91. doi: 10.1177/0961203310397412. Epub 2011 Apr 8.

PMID:
21478284
43.

Replication of genome-wide discovered breast cancer risk loci in the Cypriot population.

Loizidou MA, Hadjisavvas A, Ioannidis JP, Kyriacou K.

Breast Cancer Res Treat. 2011 Jul;128(1):267-72. doi: 10.1007/s10549-010-1319-8. Epub 2011 Jan 6.

PMID:
21210208
44.

The expression of TAG-1 in glial cells is sufficient for the formation of the juxtaparanodal complex and the phenotypic rescue of tag-1 homozygous mutants in the CNS.

Savvaki M, Theodorakis K, Zoupi L, Stamatakis A, Tivodar S, Kyriacou K, Stylianopoulou F, Karagogeos D.

J Neurosci. 2010 Oct 20;30(42):13943-54. doi: 10.1523/JNEUROSCI.2574-10.2010.

45.

Targeted prostate cancer screening in men with mutations in BRCA1 and BRCA2 detects aggressive prostate cancer: preliminary analysis of the results of the IMPACT study.

Mitra AV, Bancroft EK, Barbachano Y, Page EC, Foster CS, Jameson C, Mitchell G, Lindeman GJ, Stapleton A, Suthers G, Evans DG, Cruger D, Blanco I, Mercer C, Kirk J, Maehle L, Hodgson S, Walker L, Izatt L, Douglas F, Tucker K, Dorkins H, Clowes V, Male A, Donaldson A, Brewer C, Doherty R, Bulman B, Osther PJ, Salinas M, Eccles D, Axcrona K, Jobson I, Newcombe B, Cybulski C, Rubinstein WS, Buys S, Townshend S, Friedman E, Domchek S, Ramon Y Cajal T, Spigelman A, Teo SH, Nicolai N, Aaronson N, Ardern-Jones A, Bangma C, Dearnaley D, Eyfjord J, Falconer A, Grönberg H, Hamdy F, Johannsson O, Khoo V, Kote-Jarai Z, Lilja H, Lubinski J, Melia J, Moynihan C, Peock S, Rennert G, Schröder F, Sibley P, Suri M, Wilson P, Bignon YJ, Strom S, Tischkowitz M, Liljegren A, Ilencikova D, Abele A, Kyriacou K, van Asperen C, Kiemeney L; IMPACT Study Collaborators, Easton DF, Eeles RA.

BJU Int. 2011 Jan;107(1):28-39. doi: 10.1111/j.1464-410X.2010.09648.x. Epub 2010 Sep 14.

46.

Identification of a mutation in complement factor H-related protein 5 in patients of Cypriot origin with glomerulonephritis.

Gale DP, de Jorge EG, Cook HT, Martinez-Barricarte R, Hadjisavvas A, McLean AG, Pusey CD, Pierides A, Kyriacou K, Athanasiou Y, Voskarides K, Deltas C, Palmer A, Frémeaux-Bacchi V, de Cordoba SR, Maxwell PH, Pickering MC.

Lancet. 2010 Sep 4;376(9743):794-801. doi: 10.1016/S0140-6736(10)60670-8. Epub 2010 Aug 25.

47.

An investigation of breast cancer risk factors in Cyprus: a case control study.

Hadjisavvas A, Loizidou MA, Middleton N, Michael T, Papachristoforou R, Kakouri E, Daniel M, Papadopoulos P, Malas S, Marcou Y, Kyriacou K.

BMC Cancer. 2010 Aug 23;10:447. doi: 10.1186/1471-2407-10-447.

48.

Axonal pathology precedes demyelination in a mouse model of X-linked demyelinating/type I Charcot-Marie Tooth neuropathy.

Vavlitou N, Sargiannidou I, Markoullis K, Kyriacou K, Scherer SS, Kleopa KA.

J Neuropathol Exp Neurol. 2010 Sep;69(9):945-58. doi: 10.1097/NEN.0b013e3181efa658.

49.

Quantitative proteomic profiling of matched normal and tumor breast tissues.

Sutton CW, Rustogi N, Gurkan C, Scally A, Loizidou MA, Hadjisavvas A, Kyriacou K.

J Proteome Res. 2010 Aug 6;9(8):3891-902. doi: 10.1021/pr100113a.

PMID:
20560667
50.

Is pattern III as evidenced by US color-Doppler useful in predicting thyroid nodule malignancy? Large-scale retrospective analysis.

Cantisani V, Catania A, De Antoni E, Greco R, Caruso R, Di Segni M, Medvedyeva E, Maldur V, Guerrisi I, Kyriacou KA, Passariello R, Carbotta G, Giusti DM, Guaitoli E, Garkavaya T, Olive M, Ricci P, D'Andrea V.

Clin Ter. 2010;161(2):e49-52.

PMID:
20499019

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