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Items: 8


A Common Type 2 Diabetes Risk Variant Potentiates Activity of an Evolutionarily Conserved Islet Stretch Enhancer and Increases C2CD4A and C2CD4B Expression.

Kycia I, Wolford BN, Huyghe JR, Fuchsberger C, Vadlamudi S, Kursawe R, Welch RP, Albanus RD, Uyar A, Khetan S, Lawlor N, Bolisetty M, Mathur A, Kuusisto J, Laakso M, Ucar D, Mohlke KL, Boehnke M, Collins FS, Parker SCJ, Stitzel ML.

Am J Hum Genet. 2018 Apr 5;102(4):620-635. doi: 10.1016/j.ajhg.2018.02.020.


PWWP-DOMAIN INTERACTOR OF POLYCOMBS1 Interacts with Polycomb-Group Proteins and Histones and Regulates Arabidopsis Flowering and Development.

Hohenstatt ML, Mikulski P, Komarynets O, Klose C, Kycia I, Jeltsch A, Farrona S, Schubert D.

Plant Cell. 2018 Jan;30(1):117-133. doi: 10.1105/tpc.17.00117. Epub 2018 Jan 12.


Single-cell transcriptomes identify human islet cell signatures and reveal cell-type-specific expression changes in type 2 diabetes.

Lawlor N, George J, Bolisetty M, Kursawe R, Sun L, Sivakamasundari V, Kycia I, Robson P, Stitzel ML.

Genome Res. 2017 Feb;27(2):208-222. doi: 10.1101/gr.212720.116. Epub 2016 Nov 18.


Specificity Analysis of Histone Modification-Specific Antibodies or Reading Domains on Histone Peptide Arrays.

Kungulovski G, Kycia I, Mauser R, Jeltsch A.

Methods Mol Biol. 2015;1348:275-84. doi: 10.1007/978-1-4939-2999-3_24.


Transcriptional Regulation of the Pancreatic Islet: Implications for Islet Function.

Stitzel ML, Kycia I, Kursawe R, Ucar D.

Curr Diab Rep. 2015 Sep;15(9):66. doi: 10.1007/s11892-015-0635-0. Review.


Somatic cancer mutations in the MLL3-SET domain alter the catalytic properties of the enzyme.

Weirich S, Kudithipudi S, Kycia I, Jeltsch A.

Clin Epigenetics. 2015 Mar 28;7:36. doi: 10.1186/s13148-015-0075-3. eCollection 2015.


Application of histone modification-specific interaction domains as an alternative to antibodies.

Kungulovski G, Kycia I, Tamas R, Jurkowska RZ, Kudithipudi S, Henry C, Reinhardt R, Labhart P, Jeltsch A.

Genome Res. 2014 Nov;24(11):1842-53. doi: 10.1101/gr.170985.113. Epub 2014 Oct 9.


The Tudor domain of the PHD finger protein 1 is a dual reader of lysine trimethylation at lysine 36 of histone H3 and lysine 27 of histone variant H3t.

Kycia I, Kudithipudi S, Tamas R, Kungulovski G, Dhayalan A, Jeltsch A.

J Mol Biol. 2014 Apr 17;426(8):1651-60. doi: 10.1016/j.jmb.2013.08.009. Epub 2013 Aug 15.


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