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Items: 21

1.

Deconvolving multiplexed protease signatures with substrate reduction and activity clustering.

Zhuang Q, Holt BA, Kwong GA, Qiu P.

PLoS Comput Biol. 2019 Sep 3;15(9):e1006909. doi: 10.1371/journal.pcbi.1006909. eCollection 2019 Sep.

2.

Non-invasive early detection of acute transplant rejection via nanosensors of granzyme‚ÄČB activity.

Mac QD, Mathews DV, Kahla JA, Stoffers CM, Delmas OM, Holt BA, Adams AB, Kwong GA.

Nat Biomed Eng. 2019 Apr;3(4):281-291. doi: 10.1038/s41551-019-0358-7. Epub 2019 Feb 18.

3.

DNA-Barcoded pMHC Tetramers for Detection of Single Antigen-Specific T Cells by Digital PCR.

Dahotre SN, Chang YM, Romanov AM, Kwong GA.

Anal Chem. 2019 Feb 19;91(4):2695-2700. doi: 10.1021/acs.analchem.8b04153. Epub 2019 Jan 30.

4.

Nanosensors to Detect Protease Activity In Vivo for Noninvasive Diagnostics.

Holt BA, Mac QD, Kwong GA.

J Vis Exp. 2018 Jul 16;(137). doi: 10.3791/57937.

5.

Individually addressable and dynamic DNA gates for multiplexed cell sorting.

Dahotre SN, Chang YM, Wieland A, Stammen SR, Kwong GA.

Proc Natl Acad Sci U S A. 2018 Apr 24;115(17):4357-4362. doi: 10.1073/pnas.1714820115. Epub 2018 Apr 9.

6.

Remote Control of Mammalian Cells with Heat-Triggered Gene Switches and Photothermal Pulse Trains.

Miller IC, Gamboa Castro M, Maenza J, Weis JP, Kwong GA.

ACS Synth Biol. 2018 Apr 20;7(4):1167-1173. doi: 10.1021/acssynbio.7b00455. Epub 2018 Apr 10.

7.

Sustained-release synthetic biomarkers for monitoring thrombosis and inflammation using point-of-care compatible readouts.

Dudani JS, Buss CG, Akana RTK, Kwong GA, Bhatia SN.

Adv Funct Mater. 2016 May 3;26(17):2919-2928. doi: 10.1002/adfm.201505142. Epub 2016 Mar 22.

8.

Photoactivated Spatiotemporally-Responsive Nanosensors of in Vivo Protease Activity.

Dudani JS, Jain PK, Kwong GA, Stevens KR, Bhatia SN.

ACS Nano. 2015 Dec 22;9(12):11708-17. doi: 10.1021/acsnano.5b05946. Epub 2015 Nov 13.

9.

Mathematical framework for activity-based cancer biomarkers.

Kwong GA, Dudani JS, Carrodeguas E, Mazumdar EV, Zekavat SM, Bhatia SN.

Proc Natl Acad Sci U S A. 2015 Oct 13;112(41):12627-32. doi: 10.1073/pnas.1506925112. Epub 2015 Sep 28.

10.

Programmable probiotics for detection of cancer in urine.

Danino T, Prindle A, Kwong GA, Skalak M, Li H, Allen K, Hasty J, Bhatia SN.

Sci Transl Med. 2015 May 27;7(289):289ra84. doi: 10.1126/scitranslmed.aaa3519.

11.

Disease detection by ultrasensitive quantification of microdosed synthetic urinary biomarkers.

Warren AD, Gaylord ST, Ngan KC, Dumont Milutinovic M, Kwong GA, Bhatia SN, Walt DR.

J Am Chem Soc. 2014 Oct 1;136(39):13709-14. doi: 10.1021/ja505676h. Epub 2014 Sep 23.

12.

Self-titrating anticoagulant nanocomplexes that restore homeostatic regulation of the coagulation cascade.

Lin KY, Lo JH, Consul N, Kwong GA, Bhatia SN.

ACS Nano. 2014 Sep 23;8(9):8776-85. doi: 10.1021/nn501129q. Epub 2014 Aug 19.

13.

Point-of-care diagnostics for noncommunicable diseases using synthetic urinary biomarkers and paper microfluidics.

Warren AD, Kwong GA, Wood DK, Lin KY, Bhatia SN.

Proc Natl Acad Sci U S A. 2014 Mar 11;111(10):3671-6. doi: 10.1073/pnas.1314651111. Epub 2014 Feb 24.

14.

Nanoparticles that sense thrombin activity as synthetic urinary biomarkers of thrombosis.

Lin KY, Kwong GA, Warren AD, Wood DK, Bhatia SN.

ACS Nano. 2013 Oct 22;7(10):9001-9. doi: 10.1021/nn403550c. Epub 2013 Sep 12.

15.

Mass-encoded synthetic biomarkers for multiplexed urinary monitoring of disease.

Kwong GA, von Maltzahn G, Murugappan G, Abudayyeh O, Mo S, Papayannopoulos IA, Sverdlov DY, Liu SB, Warren AD, Popov Y, Schuppan D, Bhatia SN.

Nat Biotechnol. 2013 Jan;31(1):63-70. doi: 10.1038/nbt.2464. Epub 2012 Dec 16.

16.

Iterative in situ click chemistry assembles a branched capture agent and allosteric inhibitor for Akt1.

Millward SW, Henning RK, Kwong GA, Pitram S, Agnew HD, Deyle KM, Nag A, Hein J, Lee SS, Lim J, Pfeilsticker JA, Sharpless KB, Heath JR.

J Am Chem Soc. 2011 Nov 16;133(45):18280-8. doi: 10.1021/ja2064389. Epub 2011 Oct 24.

17.

High-density, multiplexed patterning of cells at single-cell resolution for tissue engineering and other applications.

Vermesh U, Vermesh O, Wang J, Kwong GA, Ma C, Hwang K, Heath JR.

Angew Chem Int Ed Engl. 2011 Aug 1;50(32):7378-80. doi: 10.1002/anie.201102249. Epub 2011 Jun 29. No abstract available.

18.

A clinical microchip for evaluation of single immune cells reveals high functional heterogeneity in phenotypically similar T cells.

Ma C, Fan R, Ahmad H, Shi Q, Comin-Anduix B, Chodon T, Koya RC, Liu CC, Kwong GA, Radu CG, Ribas A, Heath JR.

Nat Med. 2011 Jun;17(6):738-43. doi: 10.1038/nm.2375. Epub 2011 May 22.

19.

Modular nucleic acid assembled p/MHC microarrays for multiplexed sorting of antigen-specific T cells.

Kwong GA, Radu CG, Hwang K, Shu CJ, Ma C, Koya RC, Comin-Anduix B, Hadrup SR, Bailey RC, Witte ON, Schumacher TN, Ribas A, Heath JR.

J Am Chem Soc. 2009 Jul 22;131(28):9695-703. doi: 10.1021/ja9006707.

20.

Integrated barcode chips for rapid, multiplexed analysis of proteins in microliter quantities of blood.

Fan R, Vermesh O, Srivastava A, Yen BK, Qin L, Ahmad H, Kwong GA, Liu CC, Gould J, Hood L, Heath JR.

Nat Biotechnol. 2008 Dec;26(12):1373-8. doi: 10.1038/nbt.1507. Epub 2008 Nov 16.

21.

DNA-encoded antibody libraries: a unified platform for multiplexed cell sorting and detection of genes and proteins.

Bailey RC, Kwong GA, Radu CG, Witte ON, Heath JR.

J Am Chem Soc. 2007 Feb 21;129(7):1959-67. Epub 2007 Jan 30.

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