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When compared to plasma-based detection, osimertinib-treated non-small cell lung cancer (NSCLC) with tissue rebiopsy-confirmed acquired T790M mutation is associated with better survival.

Kwok WC, Ho JCM, Lam DCL, Lui MMS, Ip MSM, Tam TCC.

Asia Pac J Clin Oncol. 2019 Dec 4. doi: 10.1111/ajco.13287. [Epub ahead of print]


Real-time Monitoring Excitation Dynamics of Human Telomeric Guanine Quadruplexes: Effect of Folding Topology, Metal Cation, and Confinement by Nanocavity Water Pool.

Ma C, Chan RC, Chan CT, Wong AK, Kwok WM.

J Phys Chem Lett. 2019 Nov 26:7577-7585. doi: 10.1021/acs.jpclett.9b02932. [Epub ahead of print]


Administration study of recombinant human relaxin-2 in horse for doping control purpose.

Kwok WH, Choi TLS, Leung GNW, Wong ASY, Yue SK, Wan TSM, Ho ENM.

Drug Test Anal. 2019 Nov 14. doi: 10.1002/dta.2732. [Epub ahead of print]


THINGS: A database of 1,854 object concepts and more than 26,000 naturalistic object images.

Hebart MN, Dickter AH, Kidder A, Kwok WY, Corriveau A, Van Wicklin C, Baker CI.

PLoS One. 2019 Oct 15;14(10):e0223792. doi: 10.1371/journal.pone.0223792. eCollection 2019.


Antiferromagnetic Semiconductor BaFMn0.5Te with Unique Mn Ordering and Red Photoluminescence.

Chen H, McClain R, He J, Zhang C, Olding JN, Dos Reis R, Bao JK, Hadar I, Spanopoulos I, Malliakas CD, He Y, Chung DY, Kwok WK, Weiss EA, Dravid VP, Wolverton C, Kanatzidis MG.

J Am Chem Soc. 2019 Oct 30;141(43):17421-17430. doi: 10.1021/jacs.9b09382. Epub 2019 Oct 21.


Efficacy of gefitinib at reduced dose in EGFR mutant non-small cell lung carcinoma.

Kwok WC, Ho JCM, Tam TCC, Lui MMS, Ip MSM, Lam DCL.

Anticancer Drugs. 2019 Nov;30(10):1048-1051. doi: 10.1097/CAD.0000000000000849.


Strong Coupling between Magnons and Microwave Photons in On-Chip Ferromagnet-Superconductor Thin-Film Devices.

Li Y, Polakovic T, Wang YL, Xu J, Lendinez S, Zhang Z, Ding J, Khaire T, Saglam H, Divan R, Pearson J, Kwok WK, Xiao Z, Novosad V, Hoffmann A, Zhang W.

Phys Rev Lett. 2019 Sep 6;123(10):107701. doi: 10.1103/PhysRevLett.123.107701.


Systematic Assessment of Immune Marker Variation in Type 1 Diabetes: A Prospective Longitudinal Study.

Speake C, Bahnson HT, Wesley JD, Perdue N, Friedrich D, Pham MN, Lanxon-Cookson E, Kwok WW, Sehested Hansen B, von Herrath M, Greenbaum CJ.

Front Immunol. 2019 Sep 13;10:2023. doi: 10.3389/fimmu.2019.02023. eCollection 2019.


Traditional Chinese Medicine and regulatory roles on epithelial-mesenchymal transitions.

Bai J, Kwok WC, Thiery JP.

Chin Med. 2019 Sep 23;14:34. doi: 10.1186/s13020-019-0257-6. eCollection 2019. Review.


Cyclosporin A Increases Mitochondrial Buffering of Calcium: An Additional Mechanism in Delaying Mitochondrial Permeability Transition Pore Opening.

Mishra J, Davani AJ, Natarajan GK, Kwok WM, Stowe DF, Camara AKS.

Cells. 2019 Sep 7;8(9). pii: E1052. doi: 10.3390/cells8091052.


Discriminative T cell recognition of cross-reactive islet-antigens is associated with HLA-DQ8 transdimer-mediated autoimmune diabetes.

Chow IT, Gates TJ, Papadopoulos GK, Moustakas AK, Kolawole EM, Notturno RJ, McGinty JW, Torres-Chinn N, James EA, Greenbaum C, Nepom GT, Evavold BD, Kwok WW.

Sci Adv. 2019 Aug 21;5(8):eaaw9336. doi: 10.1126/sciadv.aaw9336. eCollection 2019 Aug.


A Comparative Study of High-Resolution Chemical-Shift-Eliminated Magnetic Resonance Imaging of Finger Specimens with Microcomputed Tomography.

Kwok WE, You Z, Monu J, He H.

J Clin Imaging Sci. 2019 May 24;9:19. doi: 10.25259/JCIS-20-2019. eCollection 2019.


First successful case of chemical pleurodesis with oxytetracycline through Rocket® Pleural Vent™: ambulatory pneumothorax device for pneumothorax.

Kwok WC, Cheng KC, Lam DCL, Tam TCC.

Respirol Case Rep. 2019 Aug 7;7(7):e00471. doi: 10.1002/rcr2.471. eCollection 2019 Oct.


Human CD4+ T Cells Specific for Merkel Cell Polyomavirus Localize to Merkel Cell Carcinomas and Target a Required Oncogenic Domain.

Longino NV, Yang J, Iyer JG, Ibrani D, Chow IT, Laing KJ, Campbell VL, Paulson KG, Kulikauskas RM, Church CD, James EA, Nghiem P, Kwok WW, Koelle DM.

Cancer Immunol Res. 2019 Oct;7(10):1727-1739. doi: 10.1158/2326-6066.CIR-19-0103. Epub 2019 Aug 12.


Restricted myeloperoxidase epitopes drive the adaptive immune response in MPO-ANCA vasculitis.

Free ME, Stember KG, Hess JJ, McInnis EA, Lardinois O, Hogan SL, Hu Y, Mendoza C, Le AK, Guseman AJ, Pilkinton MA, Bortone DS, Cowens K, Sidney J, Karosiene E, Peters B, James E, Kwok WW, Vincent BG, Mallal SA, Jennette JC, Ciavatta DJ, Falk RJ.

J Autoimmun. 2019 Aug 2:102306. doi: 10.1016/j.jaut.2019.102306. [Epub ahead of print]


HCV-specific CD4+ T cells of patients with acute and chronic HCV infection display high expression of TIGIT and other co-inhibitory molecules.

Ackermann C, Smits M, Woost R, Eberhard JM, Peine S, Kummer S, Marget M, Kuntzen T, Kwok WW, Lohse AW, Jacobs T, Boettler T, Schulze Zur Wiesch J.

Sci Rep. 2019 Jul 23;9(1):10624. doi: 10.1038/s41598-019-47024-8.


In Vivo Measurement of the Human Lumbar Spine Using Magnetic Resonance Imaging to Ultrasound Registration.

Koo TK, Crews RL, Kwok WE.

J Manipulative Physiol Ther. 2019 Jun;42(5):343-352. doi: 10.1016/j.jmpt.2019.03.008. Epub 2019 Jun 27.


Orbital-flop Induced Magnetoresistance Anisotropy in Rare Earth Monopnictide CeSb.

Xu J, Wu F, Bao JK, Han F, Xiao ZL, Martin I, Lyu YY, Wang YL, Chung DY, Li M, Zhang W, Pearson JE, Jiang JS, Kanatzidis MG, Kwok WK.

Nat Commun. 2019 Jun 28;10(1):2875. doi: 10.1038/s41467-019-10624-z.


Pathogenic Autoreactive T and B Cells Cross-React with Mimotopes Expressed by a Common Human Gut Commensal to Trigger Autoimmunity.

Ruff WE, Dehner C, Kim WJ, Pagovich O, Aguiar CL, Yu AT, Roth AS, Vieira SM, Kriegel C, Adeniyi O, Mulla MJ, Abrahams VM, Kwok WW, Nussinov R, Erkan D, Goodman AL, Kriegel MA.

Cell Host Microbe. 2019 Jul 10;26(1):100-113.e8. doi: 10.1016/j.chom.2019.05.003. Epub 2019 Jun 18.


Identification of Human Antigen-Specific CD4+ T-Cells with Peptide-MHC Multimer Technologies.

Kong YY, Kwok WW.

Methods Mol Biol. 2019;1988:375-386. doi: 10.1007/978-1-4939-9450-2_26.


Eleven Amino Acids of HLA-DRB1 and Fifteen Amino Acids of HLA-DRB3, 4, and 5 Include Potentially Causal Residues Responsible for the Risk of Childhood Type 1 Diabetes.

Zhao LP, Papadopoulos GK, Kwok WW, Xu B, Kong M, Moustakas AK, Bondinas GP, Carlsson A, Elding-Larsson H, Ludvigsson J, Marcus C, Persson M, Samuelsson U, Wang R, Pyo CW, Nelson WC, Geraghty DE, Lernmark Å.

Diabetes. 2019 Aug;68(8):1692-1704. doi: 10.2337/db19-0273. Epub 2019 May 24.


Breaking the 1,2-HOPO barrier with a cyclen backbone for more efficient sensitization of Eu(iii) luminescence and unprecedented two-photon excitation properties.

Dai L, Lo WS, Gu Y, Xiong Q, Wong KL, Kwok WM, Wong WT, Law GL.

Chem Sci. 2019 Mar 28;10(17):4550-4559. doi: 10.1039/c9sc00244h. eCollection 2019 May 7.


Disorder raises the critical temperature of a cuprate superconductor.

Leroux M, Mishra V, Ruff JPC, Claus H, Smylie MP, Opagiste C, Rodière P, Kayani A, Gu GD, Tranquada JM, Kwok WK, Islam Z, Welp U.

Proc Natl Acad Sci U S A. 2019 May 28;116(22):10691-10697. doi: 10.1073/pnas.1817134116. Epub 2019 May 13.


Modulation of CRTh2 expression on allergen-specific T cells following peptide immunotherapy.

Rudulier CD, Tonti E, James E, Kwok WW, Larché M.

Allergy. 2019 Nov;74(11):2157-2166. doi: 10.1111/all.13867. Epub 2019 Jun 7.


Bronchiolitis obliterans syndrome as manifestation of lung GVHD: Not the only one - Reply.

Lam DCL, Kwok WC.

Respirology. 2019 Jul;24(7):702-703. doi: 10.1111/resp.13566. Epub 2019 Apr 19. No abstract available.


A Natural 2D Heterostructure [Pb3.1Sb0.9S4][Au xTe2- x] with Large Transverse Nonsaturating Negative Magnetoresistance and High Electron Mobility.

Chen H, He J, Malliakas CD, Stoumpos CC, Rettie AJE, Bao JK, Chung DY, Kwok WK, Wolverton C, Kanatzidis MG.

J Am Chem Soc. 2019 May 8;141(18):7544-7553. doi: 10.1021/jacs.9b02599. Epub 2019 Apr 25.


Catheterised hutch diverticulum masquerading as intraperitoneal bladder perforation.

Chan VSH, Kwok WM, Cheung SCW.

Hong Kong Med J. 2019 Apr;25(2):159.e1-2. doi: 10.12809/hkmj187317. No abstract available.


Targeted evolution of pinning landscapes for large superconducting critical currents.

Sadovskyy IA, Koshelev AE, Kwok WK, Welp U, Glatz A.

Proc Natl Acad Sci U S A. 2019 May 21;116(21):10291-10296. doi: 10.1073/pnas.1817417116. Epub 2019 Apr 8.


How C-terminal additions to insulin B-chain fragments create superagonists for T cells in mouse and human type 1 diabetes.

Wang Y, Sosinowski T, Novikov A, Crawford F, White J, Jin N, Liu Z, Zou J, Neau D, Davidson HW, Nakayama M, Kwok WW, Gapin L, Marrack P, Kappler JW, Dai S.

Sci Immunol. 2019 Apr 5;4(34). pii: eaav7517. doi: 10.1126/sciimmunol.aav7517.


Epitope Selection for HLA-DQ2 Presentation: Implications for Celiac Disease and Viral Defense.

Hung SC, Hou T, Jiang W, Wang N, Qiao SW, Chow IT, Liu X, van der Burg SH, Koelle DM, Kwok WW, Sollid LM, Mellins ED.

J Immunol. 2019 May 1;202(9):2558-2569. doi: 10.4049/jimmunol.1801454. Epub 2019 Mar 29.


Slow Ca2+ Efflux by Ca2+/H+ Exchange in Cardiac Mitochondria Is Modulated by Ca2+ Re-uptake via MCU, Extra-Mitochondrial pH, and H+ Pumping by FOF1-ATPase.

Haumann J, Camara AKS, Gadicherla AK, Navarro CD, Boelens AD, Blomeyer CA, Dash RK, Boswell MR, Kwok WM, Stowe DF.

Front Physiol. 2019 Feb 4;9:1914. doi: 10.3389/fphys.2018.01914. eCollection 2018.


Ability of CP-532,903 to protect mouse hearts from ischemia/reperfusion injury is dependent on expression of A3 adenosine receptors in cardiomyoyctes.

Wan TC, Tampo A, Kwok WM, Auchampach JA.

Biochem Pharmacol. 2019 May;163:21-31. doi: 10.1016/j.bcp.2019.01.022. Epub 2019 Jan 30.


Rapid versus gradual lung function decline in bronchiolitis obliterans syndrome after haematopoietic stem cell transplantation is associated with survival outcome.

Kwok WC, Liang BM, Lui MMS, Tam TCC, Sim JPY, Tse EWC, Leung AYH, Kwong YL, Lie AKW, Ip MSM, Lam DCL.

Respirology. 2019 May;24(5):459-466. doi: 10.1111/resp.13472. Epub 2019 Jan 20.


Negative longitudinal magnetoresistance in gallium arsenide quantum wells.

Xu J, Ma MK, Sultanov M, Xiao ZL, Wang YL, Jin D, Lyu YY, Zhang W, Pfeiffer LN, West KW, Baldwin KW, Shayegan M, Kwok WK.

Nat Commun. 2019 Jan 17;10(1):287. doi: 10.1038/s41467-018-08199-2.


A Novel Approach of Identifying Immunodominant Self and Viral Antigen Cross-Reactive T Cells and Defining the Epitopes They Recognize.

Yang J, Jing L, James EA, Gebe JA, Koelle DM, Kwok WW.

Front Immunol. 2018 Dec 3;9:2811. doi: 10.3389/fimmu.2018.02811. eCollection 2018.


High Hole Mobility and Nonsaturating Giant Magnetoresistance in the New 2D Metal NaCu4Se4 Synthesized by a Unique Pathway.

Chen H, Rodrigues JNB, Rettie AJE, Song TB, Chica DG, Su X, Bao JK, Chung DY, Kwok WK, Wagner LK, Kanatzidis MG.

J Am Chem Soc. 2019 Jan 9;141(1):635-642. doi: 10.1021/jacs.8b11911. Epub 2018 Dec 26.


Der p 1-specific regulatory T-cell response during house dust mite allergen immunotherapy.

Boonpiyathad T, Sokolowska M, Morita H, Rückert B, Kast JI, Wawrzyniak M, Sangasapaviliya A, Pradubpongsa P, Fuengthong R, Thantiworasit P, Sirivichayakul S, Kwok WW, Ruxrungtham K, Akdis M, Akdis CA.

Allergy. 2019 May;74(5):976-985. doi: 10.1111/all.13684. Epub 2019 Jan 13.


DRB4*01:01 Has a Distinct Motif and Presents a Proinsulin Epitope That Is Recognized in Subjects with Type 1 Diabetes.

James EA, Gillette L, Durinovic-Bello I, Speake C, Bondinas GP, Moustakas AK, Greenbaum CJ, Papadopoulos GK, Kwok WW.

J Immunol. 2018 Dec 15;201(12):3524-3533. doi: 10.4049/jimmunol.1800723. Epub 2018 Nov 19.


Analysis of pancreatic beta cell specific CD4+ T cells reveals a predominance of proinsulin specific cells.

Blahnik G, Uchtenhagen H, Chow IT, Speake C, Greenbaum C, Kwok WW, James EA.

Cell Immunol. 2019 Jan;335:68-75. doi: 10.1016/j.cellimm.2018.11.004. Epub 2018 Nov 7.


Correction: Unsupervised capture and profiling of rare immune cells using multi-directional magnetic ratcheting.

Murray C, Miwa H, Dhar M, Park DE, Pao E, Martinez J, Kaanumale S, Loghin E, Graf J, Raddassi K, Kwok WW, Hafler D, Puleo C, Di Carlo D.

Lab Chip. 2018 Dec 7;18(23):3703. doi: 10.1039/c8lc90095g. Epub 2018 Nov 13.


Diagnosis of non-effusive feline infectious peritonitis by reverse transcriptase quantitative PCR from mesenteric lymph node fine-needle aspirates.

Dunbar D, Kwok W, Graham E, Armitage A, Irvine R, Johnston P, McDonald M, Montgomery D, Nicolson L, Robertson E, Weir W, Addie DD.

J Feline Med Surg. 2019 Oct;21(10):910-921. doi: 10.1177/1098612X18809165. Epub 2018 Nov 8.


Peroxynitrite nitrates adenine nucleotide translocase and voltage-dependent anion channel 1 and alters their interactions and association with hexokinase II in mitochondria.

Yang M, Xu Y, Heisner JS, Sun J, Stowe DF, Kwok WM, Camara AKS.

Mitochondrion. 2019 May;46:380-392. doi: 10.1016/j.mito.2018.10.002. Epub 2018 Nov 1.


Targeting DNA Binding for NF-κB as an Anticancer Approach in Hepatocellular Carcinoma.

Chung PY, Lam PL, Zhou YY, Gasparello J, Finotti A, Chilin A, Marzaro G, Gambari R, Bian ZX, Kwok WM, Wong WY, Wang X, Lam AK, Chan AS, Li X, Ma JY, Chui CH, Lam KH, Tang JC.

Cells. 2018 Oct 22;7(10). pii: E177. doi: 10.3390/cells7100177.


Peanut-specific T cell responses in patients with different clinical reactivity.

Birrueta G, Tripple V, Pham J, Manohar M, James EA, Kwok WW, Nadeau KC, Sette A, Peters B, Schulten V.

PLoS One. 2018 Oct 10;13(10):e0204620. doi: 10.1371/journal.pone.0204620. eCollection 2018.


Etanercept in patients with inflammatory hand osteoarthritis (EHOA): a multicentre, randomised, double-blind, placebo-controlled trial.

Kloppenburg M, Ramonda R, Bobacz K, Kwok WY, Elewaut D, Huizinga TWJ, Kroon FPB, Punzi L, Smolen JS, Vander Cruyssen B, Wolterbeek R, Verbruggen G, Wittoek R.

Ann Rheum Dis. 2018 Dec;77(12):1757-1764. doi: 10.1136/annrheumdis-2018-213202. Epub 2018 Oct 3.


Author Correction: Glassy Dynamics in a heavy ion irradiated NbSe2 crystal.

Eley S, Khilstrom K, Fotovat R, Xiao ZL, Chen A, Chen D, Leroux M, Welp U, Kwok WK, Civale L.

Sci Rep. 2018 Sep 26;8(1):14592. doi: 10.1038/s41598-018-32999-7.


Fluorescence and Ultrafast Fluorescence Unveil the Formation, Folding Molecularity, and Excitation Dynamics of Homo-Oligomeric and Human Telomeric i-Motifs at Acidic and Neutral pH.

Ma C, Chan RC, Chan CT, Wong AK, Chung BP, Kwok WM.

Chem Asian J. 2018 Dec 4;13(23):3706-3717. doi: 10.1002/asia.201801117. Epub 2018 Oct 30.


Photoprotection or photodamage: a direct observation of nonradiative dynamics from 2-ethylhexyl 4-dimethylaminobenzoate sunscreen agent.

Ma C, Chan CT, Chan RC, Wong AK, Chung BP, Kwok WM.

Phys Chem Chem Phys. 2018 Oct 3;20(38):24796-24806. doi: 10.1039/c8cp04447c.


First reported case of afatinib-associated toxic megacolon.

Kwok WC, Tam TCC, Lam DCL.

Respirol Case Rep. 2018 Aug 31;6(7):e00360. doi: 10.1002/rcr2.360. eCollection 2018 Oct.

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