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Neuronal Pentraxin 2 Binds PNNs and Enhances PNN Formation.

Van't Spijker HM, Rowlands D, Rossier J, Haenzi B, Fawcett JW, Kwok JCF.

Neural Plast. 2019 Oct 20;2019:6804575. doi: 10.1155/2019/6804575. eCollection 2019.


Systemic α-synuclein injection triggers selective neuronal pathology as seen in patients with Parkinson's disease.

Kuan WL, Stott K, He X, Wood TC, Yang S, Kwok JCF, Hall K, Zhao Y, Tietz O, Aigbirhio FI, Vernon AC, Barker RA.

Mol Psychiatry. 2019 Nov 22. doi: 10.1038/s41380-019-0608-9. [Epub ahead of print]


Adaptation of tape removal test for measurement of sensitivity in perineal area of rat.

Neumannova K, Machova-Urdzikova L, Kwok JCF, Fawcett JW, Jendelova P.

Exp Neurol. 2020 Feb;324:113097. doi: 10.1016/j.expneurol.2019.113097. Epub 2019 Nov 9.


Visualization of Perineuronal Nets in Central Nervous System Tissue Sections.

Souter L, Kwok JCF.

Methods Mol Biol. 2020;2043:251-260. doi: 10.1007/978-1-4939-9698-8_20.


Pulmonary metastasis from a World Health Organization grade I intracranial parasagittal meningioma: a case report.

Woo PYM, Hung RSL, Takemura S, Chan KY, Kwok JCK.

Hong Kong Med J. 2019 Aug;25(4):326-328. doi: 10.12809/hkmj177059. No abstract available.


The potential of memory enhancement through modulation of perineuronal nets.

Duncan JA, Foster R, Kwok JCF.

Br J Pharmacol. 2019 Sep;176(18):3611-3621. doi: 10.1111/bph.14672. Epub 2019 May 20. Review.


Post Translational Modulation of β-Amyloid Precursor Protein Trafficking to the Cell Surface Alters Neuronal Iron Homeostasis.

Tsatsanis A, Dickens S, Kwok JCF, Wong BX, Duce JA.

Neurochem Res. 2019 Jun;44(6):1367-1374. doi: 10.1007/s11064-019-02747-y. Epub 2019 Feb 22.


Model development and comparison of low hemorrhage-risk endoluminal patch thrombolytic treatment for ischemic stroke.

Qin Z, Ciucci F, Chon CH, Kwok JCK, Lam DCC.

Med Eng Phys. 2018 Nov;61:32-40. doi: 10.1016/j.medengphy.2018.08.003. Epub 2018 Sep 1.


Perineuronal Nets in Spinal Motoneurones: Chondroitin Sulphate Proteoglycan around Alpha Motoneurones.

Irvine SF, Kwok JCF.

Int J Mol Sci. 2018 Apr 12;19(4). pii: E1172. doi: 10.3390/ijms19041172.


Glycosaminoglycans in extracellular matrix organisation: are concepts from soft matter physics key to understanding the formation of perineuronal nets?

Richter RP, Baranova NS, Day AJ, Kwok JC.

Curr Opin Struct Biol. 2018 Jun;50:65-74. doi: 10.1016/ Epub 2017 Dec 21. Review.


A Sweet Talk: The Molecular Systems of Perineuronal Nets in Controlling Neuronal Communication.

van 't Spijker HM, Kwok JCF.

Front Integr Neurosci. 2017 Dec 1;11:33. doi: 10.3389/fnint.2017.00033. eCollection 2017. Review.


Control of Cell Shape, Neurite Outgrowth, and Migration by a Nogo-A/HSPG Interaction.

Kempf A, Boda E, Kwok JCF, Fritz R, Grande V, Kaelin AM, Ristic Z, Schmandke A, Schmandke A, Tews B, Fawcett JW, Pertz O, Buffo A, Schwab ME.

Dev Cell. 2017 Oct 9;43(1):24-34.e5. doi: 10.1016/j.devcel.2017.08.014. Epub 2017 Sep 21.


Antibody recognizing 4-sulfated chondroitin sulfate proteoglycans restores memory in tauopathy-induced neurodegeneration.

Yang S, Hilton S, Alves JN, Saksida LM, Bussey T, Matthews RT, Kitagawa H, Spillantini MG, Kwok JCF, Fawcett JW.

Neurobiol Aging. 2017 Nov;59:197-209. doi: 10.1016/j.neurobiolaging.2017.08.002. Epub 2017 Aug 9.


Selective rab11 transport and the intrinsic regenerative ability of CNS axons.

Koseki H, Donegá M, Lam BY, Petrova V, van Erp S, Yeo GS, Kwok JC, Ffrench-Constant C, Eva R, Fawcett JW.

Elife. 2017 Aug 8;6. pii: e26956. doi: 10.7554/eLife.26956.


Mechanical behavior of rf-treated thrombus in mechanical thrombectomy.

Chon CH, Qin Z, Kwok JC, Lam DC.

Med Eng Phys. 2017 Sep;47:184-189. doi: 10.1016/j.medengphy.2017.06.011. Epub 2017 Jul 5.


Brain ageing changes proteoglycan sulfation, rendering perineuronal nets more inhibitory.

Foscarin S, Raha-Chowdhury R, Fawcett JW, Kwok JCF.

Aging (Albany NY). 2017 Jun 28;9(6):1607-1622. doi: 10.18632/aging.101256.


Progressive hemiparesis in a young man: Hemicerebral atrophy as the initial manifestation of basal ganglia germinoma.

Woo PYM, Chu ACH, Chan KY, Kwok JCK.

Asian J Neurosurg. 2017 Jan-Mar;12(1):65-68. doi: 10.4103/1793-5482.145083.


In vitro examination of the pressure effect on clot dissolution with thrombolytic patch.

Zhen Qin, Chi Hang Chon, Kwok JC, Lam DC.

Conf Proc IEEE Eng Med Biol Soc. 2016 Aug;2016:549-552. doi: 10.1109/EMBC.2016.7590761.


Characterization of thrombus stiffening in radio frequency (rf) Mechanical thrombectomy.

Chon CC, Qin JZ, Kwok JC, Lam DC.

Conf Proc IEEE Eng Med Biol Soc. 2016 Aug;2016:355-358. doi: 10.1109/EMBC.2016.7590713.


Casting a Wide Net: Role of Perineuronal Nets in Neural Plasticity.

Sorg BA, Berretta S, Blacktop JM, Fawcett JW, Kitagawa H, Kwok JC, Miquel M.

J Neurosci. 2016 Nov 9;36(45):11459-11468. Review.


The Chemorepulsive Protein Semaphorin 3A and Perineuronal Net-Mediated Plasticity.

de Winter F, Kwok JC, Fawcett JW, Vo TT, Carulli D, Verhaagen J.

Neural Plast. 2016;2016:3679545. doi: 10.1155/2016/3679545. Epub 2016 Jan 14. Review.


Perineuronal Nets and CNS Plasticity and Repair.

Carulli D, Kwok JC, Pizzorusso T.

Neural Plast. 2016;2016:4327082. doi: 10.1155/2016/4327082. Epub 2016 Feb 16. No abstract available.


Feasibility examination of isolated zonal thrombolysis using Raman spectroscopy.

Zhen Qin, Chi Hang Chon, Lam AK, Kwok JC, Yuen MM, Lam DC.

Conf Proc IEEE Eng Med Biol Soc. 2015 Aug;2015:1353-6. doi: 10.1109/EMBC.2015.7318619.


In-vitro testing of RF-enabled low force mechanical thrombectomy for ischemic stroke.

Chi Hang Chon, Zhen Qin, Lam AK, Kwok JC, Yuen MM, Lam DC.

Conf Proc IEEE Eng Med Biol Soc. 2015 Aug;2015:1349-52. doi: 10.1109/EMBC.2015.7318618.


A Method for the Isolation and Culture of Adult Rat Retinal Pigment Epithelial (RPE) Cells to Study Retinal Diseases.

Heller JP, Kwok JC, Vecino E, Martin KR, Fawcett JW.

Front Cell Neurosci. 2015 Nov 20;9:449. doi: 10.3389/fncel.2015.00449. eCollection 2015.


"GAG-ing with the neuron": The role of glycosaminoglycan patterning in the central nervous system.

Smith PD, Coulson-Thomas VJ, Foscarin S, Kwok JC, Fawcett JW.

Exp Neurol. 2015 Dec;274(Pt B):100-14. doi: 10.1016/j.expneurol.2015.08.004. Epub 2015 Aug 12. Review.


Full length talin stimulates integrin activation and axon regeneration.

Tan CL, Kwok JC, Heller JP, Zhao R, Eva R, Fawcett JW.

Mol Cell Neurosci. 2015 Sep;68:1-8. doi: 10.1016/j.mcn.2015.03.011. Epub 2015 Mar 11.


Glycosaminoglycans and glycomimetics in the central nervous system.

Rowlands D, Sugahara K, Kwok JC.

Molecules. 2015 Feb 19;20(3):3527-48. doi: 10.3390/molecules20033527. Review.


Neural ECM in regeneration and rehabilitation.

Yang S, Kwok JC, Fawcett JW.

Prog Brain Res. 2014;214:179-92. doi: 10.1016/B978-0-444-63486-3.00008-6. Review.


Astrocyte response to motor neuron injury promotes structural synaptic plasticity via STAT3-regulated TSP-1 expression.

Tyzack GE, Sitnikov S, Barson D, Adams-Carr KL, Lau NK, Kwok JC, Zhao C, Franklin RJ, Karadottir RT, Fawcett JW, Lakatos A.

Nat Commun. 2014 Jul 11;5:4294. doi: 10.1038/ncomms5294.


Targeting inhibitory chondroitin sulphate proteoglycans to promote plasticity after injury.

Kwok JC, Heller JP, Zhao RR, Fawcett JW.

Methods Mol Biol. 2014;1162:127-38. doi: 10.1007/978-1-4939-0777-9_10.


The relationship between glial cell mechanosensitivity and foreign body reactions in the central nervous system.

Moshayedi P, Ng G, Kwok JC, Yeo GS, Bryant CE, Fawcett JW, Franze K, Guck J.

Biomaterials. 2014 Apr;35(13):3919-25. doi: 10.1016/j.biomaterials.2014.01.038. Epub 2014 Feb 11.


Characterization of pressure reduction in coil-filled aneurysm under flow of human blood with and without anti-coagulant.

Lam AK, Ko MW, Leung LK, Kwok JC, Yuen MM, Lam DC.

Conf Proc IEEE Eng Med Biol Soc. 2013;2013:739-42. doi: 10.1109/EMBC.2013.6609606.


Semaphorin 3A binds to the perineuronal nets via chondroitin sulfate type E motifs in rodent brains.

Dick G, Tan CL, Alves JN, Ehlert EM, Miller GM, Hsieh-Wilson LC, Sugahara K, Oosterhof A, van Kuppevelt TH, Verhaagen J, Fawcett JW, Kwok JC.

J Biol Chem. 2013 Sep 20;288(38):27384-95. doi: 10.1074/jbc.M111.310029. Epub 2013 Aug 12.


Human placenta as an ex vivo vascular model for neurointerventional research.

Kwok JC, Huang W, Leung WC, Chan SK, Chan KY, Leung KM, Chu AC, Lam AK.

J Neurointerv Surg. 2014 Jun;6(5):394-9. doi: 10.1136/neurintsurg-2013-010813. Epub 2013 Jul 31.


The chemorepulsive axon guidance protein semaphorin3A is a constituent of perineuronal nets in the adult rodent brain.

Vo T, Carulli D, Ehlert EM, Kwok JC, Dick G, Mecollari V, Moloney EB, Neufeld G, de Winter F, Fawcett JW, Verhaagen J.

Mol Cell Neurosci. 2013 Sep;56:186-200. doi: 10.1016/j.mcn.2013.04.009. Epub 2013 May 9.


Effects of aging and tai chi on a finger-pointing task with a choice paradigm.

Tsang WW, Kwok JC, Hui-Chan CW.

Evid Based Complement Alternat Med. 2013;2013:653437. doi: 10.1155/2013/653437. Epub 2013 Feb 17.


Medication adherence: is it a hidden drug-related problem in hidden elderly?

Lee VW, Pang KK, Hui KC, Kwok JC, Leung SL, Yu DS, Lee DT.

Geriatr Gerontol Int. 2013 Oct;13(4):978-85. doi: 10.1111/ggi.12042. Epub 2013 Mar 3.


Angioplasty and stenting for intracranial atherosclerotic stenosis: position statement of the Hong Kong Society of Interventional and Therapeutic Neuroradiology.

Yu SC, Cheng HK, Cheng PW, Lui WM, Leung KM, Tan CB, Pang KY, Wong GK, Cheung YL, Lee R, Wong YC, Wong CK, Kwok JC; Hong Kong Society of Interventional and Therapeutic Neuroradiology.

Hong Kong Med J. 2013 Feb;19(1):69-73.


Effects of digesting chondroitin sulfate proteoglycans on plasticity in cat primary visual cortex.

Vorobyov V, Kwok JC, Fawcett JW, Sengpiel F.

J Neurosci. 2013 Jan 2;33(1):234-43. doi: 10.1523/JNEUROSCI.2283-12.2013.


Bilateral pneumothoraces in a patient undergoing minimally invasive parathyroidectomy during monitored anesthesia care.

Kwok JC, Tarnal VC, Ramachandran SK, Gauger PG.

J Clin Anesth. 2013 Feb;25(1):81-3. doi: 10.1016/j.jclinane.2012.08.001. Epub 2012 Dec 12. No abstract available.


Kindlin-1 enhances axon growth on inhibitory chondroitin sulfate proteoglycans and promotes sensory axon regeneration.

Tan CL, Andrews MR, Kwok JC, Heintz TG, Gumy LF, Fässler R, Fawcett JW.

J Neurosci. 2012 May 23;32(21):7325-35. doi: 10.1523/JNEUROSCI.5472-11.2012.


Chondroitin sulfates in the developing rat hindbrain confine commissural projections of vestibular nuclear neurons.

Kwok JC, Yuen YL, Lau WK, Zhang FX, Fawcett JW, Chan YS, Shum DK.

Neural Dev. 2012 Feb 3;7:6. doi: 10.1186/1749-8104-7-6.


Chondroitin sulfate: a key molecule in the brain matrix.

Kwok JC, Warren P, Fawcett JW.

Int J Biochem Cell Biol. 2012 Apr;44(4):582-6. doi: 10.1016/j.biocel.2012.01.004. Epub 2012 Jan 14. Review.


Extracellular matrix and perineuronal nets in CNS repair.

Kwok JC, Dick G, Wang D, Fawcett JW.

Dev Neurobiol. 2011 Nov;71(11):1073-89. doi: 10.1002/dneu.20974. Review.


Lentiviral vectors express chondroitinase ABC in cortical projections and promote sprouting of injured corticospinal axons.

Zhao RR, Muir EM, Alves JN, Rickman H, Allan AY, Kwok JC, Roet KC, Verhaagen J, Schneider BL, Bensadoun JC, Ahmed SG, Yáñez-Muñoz RJ, Keynes RJ, Fawcett JW, Rogers JH.

J Neurosci Methods. 2011 Sep 30;201(1):228-38. doi: 10.1016/j.jneumeth.2011.08.003. Epub 2011 Aug 9.


6-Sulphated chondroitins have a positive influence on axonal regeneration.

Lin R, Rosahl TW, Whiting PJ, Fawcett JW, Kwok JC.

PLoS One. 2011;6(7):e21499. doi: 10.1371/journal.pone.0021499. Epub 2011 Jul 1.


Integrin activation promotes axon growth on inhibitory chondroitin sulfate proteoglycans by enhancing integrin signaling.

Tan CL, Kwok JC, Patani R, Ffrench-Constant C, Chandran S, Fawcett JW.

J Neurosci. 2011 Apr 27;31(17):6289-95. doi: 10.1523/JNEUROSCI.0008-11.2011.

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