Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 98

1.
2.

An innovative anti-cancer Chinese herbal formula exhibited multi-targeted efficacies in metastatic breast cancer mouse model.

Yue GG, Lee JK, Chan BC, Kwok HF, Hoi SW, Sze DM, Fung KP, Leung PC, Lau CB.

Chin Med. 2018 Dec 22;13:64. doi: 10.1186/s13020-018-0222-9. eCollection 2018.

3.

DNA replication licensing proteins: Saints and sinners in cancer.

Mughal MJ, Mahadevappa R, Kwok HF.

Semin Cancer Biol. 2018 Nov 28. pii: S1044-579X(18)30138-X. doi: 10.1016/j.semcancer.2018.11.009. [Epub ahead of print] Review.

PMID:
30502375
4.

Rapid discrimination of colon cancer cells with single base mutation in KRAS gene segment using laser tweezers Raman spectroscopy.

Liu M, Liu X, Huang Z, Tang X, Lin X, Xu Y, Chen G, Kwok HF, Lin Y, Feng S.

J Biophotonics. 2018 Nov 28:e201800332. doi: 10.1002/jbio.201800332. [Epub ahead of print]

PMID:
30485680
5.

Commentary: High-throughput Strategy Accelerates the Progress of Marine Anticancer Peptide Drug Development.

Lyu P, Kwok HF.

Recent Pat Anticancer Drug Discov. 2018 Nov 14. doi: 10.2174/1574892813999181114152127. [Epub ahead of print]

PMID:
30474536
6.

Habu coagulotoxicity: Clinical implications of the functional diversification of Protobothrops snake venoms upon blood clotting factors.

Debono J, Bos MHA, Nouwens A, Ge L, Frank N, Kwok HF, Fry BG.

Toxicol In Vitro. 2019 Mar;55:62-74. doi: 10.1016/j.tiv.2018.11.008. Epub 2018 Nov 22.

PMID:
30471431
7.

Pharmacoinformatic Approach to Explore the Antidote Potential of Phytochemicals on Bungarotoxin from Indian Krait, Bungarus caeruleus.

Rajendran BK, Xavier Suresh M, Bhaskaran SP, Harshitha Y, Gaur U, Kwok HF.

Comput Struct Biotechnol J. 2018 Oct 31;16:450-461. doi: 10.1016/j.csbj.2018.10.005. eCollection 2018.

8.
9.

Targeting PD-L1 Protein: Translation, Modification and Transport.

Wei R, Guo L, Wang Q, Miao J, Kwok HF, Lin Y.

Curr Protein Pept Sci. 2019;20(1):82-91. doi: 10.2174/1389203719666180928105632. Review.

PMID:
30264678
10.

DNA Replication Licensing Protein MCM10 Promotes Tumor Progression and Is a Novel Prognostic Biomarker and Potential Therapeutic Target in Breast Cancer.

Mahadevappa R, Neves H, Yuen SM, Jameel M, Bai Y, Yuen HF, Zhang SD, Zhu Y, Lin Y, Kwok HF.

Cancers (Basel). 2018 Aug 22;10(9). pii: E282. doi: 10.3390/cancers10090282.

11.

Biological Activities of Cationicity-Enhanced and Hydrophobicity-Optimized Analogues of an Antimicrobial Peptide, Dermaseptin-PS3, from the Skin Secretion of Phyllomedusa sauvagii.

Tan Y, Chen X, Ma C, Xi X, Wang L, Zhou M, Burrows JF, Kwok HF, Chen T.

Toxins (Basel). 2018 Aug 7;10(8). pii: E320. doi: 10.3390/toxins10080320.

12.

Triggering of cancer cell cycle arrest by a novel scorpion venom-derived peptide-Gonearrestide.

Li B, Lyu P, Xi X, Ge L, Mahadevappa R, Shaw C, Kwok HF.

J Cell Mol Med. 2018 Sep;22(9):4460-4473. doi: 10.1111/jcmm.13745. Epub 2018 Jul 11.

13.

In vitro and clinical data analysis of Osteopontin as a prognostic indicator in colorectal cancer.

Wei R, Wong JPC, Lyu P, Xi X, Tong O, Zhang SD, Yuen HF, Shirasawa S, Kwok HF.

J Cell Mol Med. 2018 Sep;22(9):4097-4105. doi: 10.1111/jcmm.13686. Epub 2018 May 30.

14.

Does size matter? Venom proteomic and functional comparison between night adder species (Viperidae: Causus) with short and long venom glands.

Coimbra FCP, Dobson J, Zdenek CN, Op den Brouw B, Hamilton B, Debono J, Masci P, Frank N, Ge L, Kwok HF, Fry BG.

Comp Biochem Physiol C Toxicol Pharmacol. 2018 Sep;211:7-14. doi: 10.1016/j.cbpc.2018.05.003. Epub 2018 May 21.

PMID:
29758383
15.

The Roles of Protein Tyrosine Phosphatases in Hepatocellular Carcinoma.

Huang Y, Zhang Y, Ge L, Lin Y, Kwok HF.

Cancers (Basel). 2018 Mar 20;10(3). pii: E82. doi: 10.3390/cancers10030082. Review.

16.

Proteomic and functional variation within black snake venoms (Elapidae: Pseudechis).

Goldenberg J, Cipriani V, Jackson TNW, Arbuckle K, Debono J, Dashevsky D, Panagides N, Ikonomopoulou MP, Koludarov I, Li B, Santana RC, Nouwens A, Jones A, Hay C, Dunstan N, Allen L, Bush B, Miles JJ, Ge L, Kwok HF, Fry BG.

Comp Biochem Physiol C Toxicol Pharmacol. 2018 Feb;205:53-61. doi: 10.1016/j.cbpc.2018.01.001. Epub 2018 Jan 17.

PMID:
29353015
17.

Problem behaviours and psychotropic medication use in intellectual disability: a multinational cross-sectional survey.

Perry BI, Cooray SE, Mendis J, Purandare K, Wijeratne A, Manjubhashini S, Dasari M, Esan F, Gunaratna I, Naseem RA, Hoare S, Chester V, Roy A, Devapriam J, Alexander R, Kwok HF.

J Intellect Disabil Res. 2018 Feb;62(2):140-149. doi: 10.1111/jir.12471.

PMID:
29349928
18.

Venom-based peptide therapy: insights into anti-cancer mechanism.

Ma R, Mahadevappa R, Kwok HF.

Oncotarget. 2017 Oct 11;8(59):100908-100930. doi: 10.18632/oncotarget.21740. eCollection 2017 Nov 21. Review.

19.

Clinical and in vitro analysis of Osteopontin as a prognostic indicator and unveil its potential downstream targets in bladder cancer.

Wong JPC, Wei R, Lyu P, Tong OLH, Zhang SD, Wen Q, Yuen HF, El-Tanani M, Kwok HF.

Int J Biol Sci. 2017 Nov 1;13(11):1373-1386. doi: 10.7150/ijbs.21457. eCollection 2017.

20.

The Roles of microRNAs in Regulating the Expression of PD-1/PD-L1 Immune Checkpoint.

Wang Q, Lin W, Tang X, Li S, Guo L, Lin Y, Kwok HF.

Int J Mol Sci. 2017 Nov 27;18(12). pii: E2540. doi: 10.3390/ijms18122540. Review.

21.

Expression of minichromosome maintenance genes in renal cell carcinoma.

Zhong H, Chen B, Neves H, Xing J, Ye Y, Lin Y, Zhuang G, Zhang SD, Huang J, Kwok HF.

Cancer Manag Res. 2017 Nov 15;9:637-647. doi: 10.2147/CMAR.S146528. eCollection 2017.

22.

β-defensin 1 expression in HCV infected liver/liver cancer: an important role in protecting HCV progression and liver cancer development.

Ling YM, Chen JY, Guo L, Wang CY, Tan WT, Wen Q, Zhang SD, Deng GH, Lin Y, Kwok HF.

Sci Rep. 2017 Oct 17;7(1):13404. doi: 10.1038/s41598-017-13332-0.

23.

Vascular ADAM17 (a Disintegrin and Metalloproteinase Domain 17) Is Required for Angiotensin II/β-Aminopropionitrile-Induced Abdominal Aortic Aneurysm.

Kawai T, Takayanagi T, Forrester SJ, Preston KJ, Obama T, Tsuji T, Kobayashi T, Boyer MJ, Cooper HA, Kwok HF, Hashimoto T, Scalia R, Rizzo V, Eguchi S.

Hypertension. 2017 Nov;70(5):959-963. doi: 10.1161/HYPERTENSIONAHA.117.09822. Epub 2017 Sep 25.

24.

Using Ultra-Performance Liquid Chromatography Quadrupole Time of Flight Mass Spectrometry-Based Chemometrics for the Identification of Anti-angiogenic Biflavonoids from Edible Garcinia Species.

Li P, Yue GG, Kwok HF, Long CL, Lau CB, Kennelly EJ.

J Agric Food Chem. 2017 Sep 27;65(38):8348-8355. doi: 10.1021/acs.jafc.7b02867. Epub 2017 Sep 19.

PMID:
28926234
25.

Venom Peptides: Improving Specificity in Cancer Therapy.

Mahadevappa R, Ma R, Kwok HF.

Trends Cancer. 2017 Sep;3(9):611-614. doi: 10.1016/j.trecan.2017.07.004. Epub 2017 Aug 10. Review.

PMID:
28867164
26.

Osteopontin -- a promising biomarker for cancer therapy.

Wei R, Wong JPC, Kwok HF.

J Cancer. 2017 Jul 15;8(12):2173-2183. doi: 10.7150/jca.20480. eCollection 2017. Review.

27.

Enter the Dragon: The Dynamic and Multifunctional Evolution of Anguimorpha Lizard Venoms.

Koludarov I, Jackson TN, Brouw BOD, Dobson J, Dashevsky D, Arbuckle K, Clemente CJ, Stockdale EJ, Cochran C, Debono J, Stephens C, Panagides N, Li B, Manchadi MR, Violette A, Fourmy R, Hendrikx I, Nouwens A, Clements J, Martelli P, Kwok HF, Fry BG.

Toxins (Basel). 2017 Aug 6;9(8). pii: E242. doi: 10.3390/toxins9080242.

28.

DAPK1 as an independent prognostic marker in liver cancer.

Li L, Guo L, Wang Q, Liu X, Zeng Y, Wen Q, Zhang S, Kwok HF, Lin Y, Liu J.

PeerJ. 2017 Jul 19;5:e3568. doi: 10.7717/peerj.3568. eCollection 2017.

29.

Venom Peptides and Toxins - A Prospective Spearhead in Cancer Treatment.

Wong JPC, Li B, Kwok HF.

Comb Chem High Throughput Screen. 2017;20(5):357-375. doi: 10.2174/1386207320666170621130425. Review.

PMID:
28637411
30.

In sickness and in health: The many roles of the minichromosome maintenance proteins.

Neves H, Kwok HF.

Biochim Biophys Acta Rev Cancer. 2017 Aug;1868(1):295-308. doi: 10.1016/j.bbcan.2017.06.001. Epub 2017 Jun 1. Review.

PMID:
28579200
31.

Anti-tumor effects of a 'human & mouse cross-reactive' anti-ADAM17 antibody in a pancreatic cancer model in vivo.

Ye J, Yuen SM, Murphy G, Xie R, Kwok HF.

Eur J Pharm Sci. 2017 Dec 15;110:62-69. doi: 10.1016/j.ejps.2017.05.057. Epub 2017 May 26.

PMID:
28554668
32.

Coagulating Colubrids: Evolutionary, Pathophysiological and Biodiscovery Implications of Venom Variations between Boomslang (Dispholidus typus) and Twig Snake (Thelotornis mossambicanus).

Debono J, Dobson J, Casewell NR, Romilio A, Li B, Kurniawan N, Mardon K, Weisbecker V, Nouwens A, Kwok HF, Fry BG.

Toxins (Basel). 2017 May 19;9(5). pii: E171. doi: 10.3390/toxins9050171.

33.

Correlation between ontogenetic dietary shifts and venom variation in Australian brown snakes (Pseudonaja).

Cipriani V, Debono J, Goldenberg J, Jackson TNW, Arbuckle K, Dobson J, Koludarov I, Li B, Hay C, Dunstan N, Allen L, Hendrikx I, Kwok HF, Fry BG.

Comp Biochem Physiol C Toxicol Pharmacol. 2017 Jul;197:53-60. doi: 10.1016/j.cbpc.2017.04.007. Epub 2017 Apr 27.

PMID:
28457945
34.

Whole extracts of Radix Achyranthis Bidentatae and Radix Cyathulae promote angiogenesis in human umbilical vein endothelial cells in vitro and in zebrafish in vivo.

Zhou X, Siu WS, Zhang C, Liu CL, Cheng L, Kwok HF, Fung CH, Tam JC, Lau CP, Lau CB, Leung PC, Hung LK, Ko CH.

Exp Ther Med. 2017 Mar;13(3):1032-1038. doi: 10.3892/etm.2017.4053. Epub 2017 Jan 17.

35.

The prognostic significance of Cdc6 and Cdt1 in breast cancer.

Mahadevappa R, Neves H, Yuen SM, Bai Y, McCrudden CM, Yuen HF, Wen Q, Zhang SD, Kwok HF.

Sci Rep. 2017 Apr 20;7(1):985. doi: 10.1038/s41598-017-00998-9.

36.

The prognostic significance of DAPK1 in bladder cancer.

Xie JY, Chen PC, Zhang JL, Gao ZS, Neves H, Zhang SD, Wen Q, Chen WD, Kwok HF, Lin Y.

PLoS One. 2017 Apr 7;12(4):e0175290. doi: 10.1371/journal.pone.0175290. eCollection 2017.

37.

Identification of TWIST-interacting genes in prostate cancer.

Lyu P, Zhang SD, Yuen HF, McCrudden CM, Wen Q, Chan KW, Kwok HF.

Sci China Life Sci. 2017 Apr;60(4):386-396. doi: 10.1007/s11427-016-0262-6. Epub 2017 Jan 22.

PMID:
28120266
38.

Phytochemicals - A Novel and Prominent Source of Anti-cancer Drugs Against Colorectal Cancer.

Mahadevappa R, Kwok HF.

Comb Chem High Throughput Screen. 2017;20(5):376-394. doi: 10.2174/1386207320666170112141833. Review.

PMID:
28078982
39.

CD133 in brain tumor: the prognostic factor.

Li B, McCrudden CM, Yuen HF, Xi X, Lyu P, Chan KW, Zhang SD, Kwok HF.

Oncotarget. 2017 Feb 14;8(7):11144-11159. doi: 10.18632/oncotarget.14406.

40.

Digitoxin synergizes with sorafenib to inhibit hepatocelluar carcinoma cell growth without inhibiting cell migration.

Xiao Y, Yan W, Guo L, Meng C, Li B, Neves H, Chen PC, Li L, Huang Y, Kwok HF, Lin Y.

Mol Med Rep. 2017 Feb;15(2):941-947. doi: 10.3892/mmr.2016.6096. Epub 2016 Dec 30.

PMID:
28035421
41.

New potential beneficial effects of actein, a triterpene glycoside isolated from Cimicifuga species, in breast cancer treatment.

Yue GG, Xie S, Lee JK, Kwok HF, Gao S, Nian Y, Wu XX, Wong CK, Qiu MH, Lau CB.

Sci Rep. 2016 Oct 12;6:35263. doi: 10.1038/srep35263.

42.

Vascular ADAM17 as a Novel Therapeutic Target in Mediating Cardiovascular Hypertrophy and Perivascular Fibrosis Induced by Angiotensin II.

Takayanagi T, Forrester SJ, Kawai T, Obama T, Tsuji T, Elliott KJ, Nuti E, Rossello A, Kwok HF, Scalia R, Rizzo V, Eguchi S.

Hypertension. 2016 Oct;68(4):949-955. doi: 10.1161/HYPERTENSIONAHA.116.07620. Epub 2016 Aug 1.

43.

Anti-angiogenic Activity and Mechanism of Sesquiterpene Lactones from Centipeda minima.

Huang W, Yu X, Liang N, Ge W, Kwok HF, Lau CB, Li Y, Chung HY.

Nat Prod Commun. 2016 Apr;11(4):435-8.

PMID:
27396185
44.

Combined therapy using bevacizumab and turmeric ethanolic extract (with absorbable curcumin) exhibited beneficial efficacy in colon cancer mice.

Yue GG, Kwok HF, Lee JK, Jiang L, Wong EC, Gao S, Wong HL, Li L, Chan KM, Leung PC, Fung KP, Zuo Z, Lau CB.

Pharmacol Res. 2016 Sep;111:43-57. doi: 10.1016/j.phrs.2016.05.025. Epub 2016 May 27.

PMID:
27241019
45.

Two Novel Dermaseptin-Like Antimicrobial Peptides with Anticancer Activities from the Skin Secretion of Pachymedusa dacnicolor.

Shi D, Hou X, Wang L, Gao Y, Wu D, Xi X, Zhou M, Kwok HF, Duan J, Chen T, Shaw C.

Toxins (Basel). 2016 May 12;8(5). pii: E144. doi: 10.3390/toxins8050144.

46.

Temporal establishment of neural cell identity in vivo and in vitro.

Yuen SM, Kwok HF.

J Tissue Eng Regen Med. 2017 Sep;11(9):2582-2589. doi: 10.1002/term.2158. Epub 2016 Apr 6. Review.

PMID:
27061786
47.

Development of a specific affinity-matured exosite inhibitor to MT1-MMP that efficiently inhibits tumor cell invasion in vitro and metastasis in vivo.

Botkjaer KA, Kwok HF, Terp MG, Karatt-Vellatt A, Santamaria S, McCafferty J, Andreasen PA, Itoh Y, Ditzel HJ, Murphy G.

Oncotarget. 2016 Mar 29;7(13):16773-92. doi: 10.18632/oncotarget.7780.

48.

Association between the expression levels of TAZ, AXL and CTGF and clinicopathological parameters in patients with colon cancer.

Zhang SD, McCrudden CM, Yuen HF, Leung KL, Hong WJ, Kwok HF.

Oncol Lett. 2016 Feb;11(2):1223-1229. Epub 2015 Dec 3. Erratum in: Oncol Lett. 2016 Jun;11(6):3904.

49.

Recent advances in the field of anti-cancer immunotherapy.

Neves H, Kwok HF.

BBA Clin. 2015 Apr 18;3:280-8. doi: 10.1016/j.bbacli.2015.04.001. eCollection 2015 Jun. Review.

50.

Prognostic significance of combining VEGFA, FLT1 and KDR mRNA expression in lung cancer.

Zhang SD, McCrudden CM, Kwok HF.

Oncol Lett. 2015 Sep;10(3):1893-1901. Epub 2015 Jun 24.

Supplemental Content

Support Center