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Items: 1 to 50 of 108

1.

Novel Therapeutic Anti-ADAM17 Antibody A9(B8) Enhances EGFR-TKI-Mediated Anticancer Activity in NSCLC.

Yang Z, Chan KI, Kwok HF, Tam KY.

Transl Oncol. 2019 Aug 23;12(11):1516-1524. doi: 10.1016/j.tranon.2019.08.003. [Epub ahead of print]

2.

A review on the immunomodulatory activity of Acanthopanax senticosus and its active components.

Lau KM, Yue GG, Chan YY, Kwok HF, Gao S, Wong CW, Lau CB.

Chin Med. 2019 Jul 31;14:25. doi: 10.1186/s13020-019-0250-0. eCollection 2019. Review.

3.

Bioevaluation of Ranatuerin-2Pb from the Frog Skin Secretion of Rana pipiens and its Truncated Analogues.

Zhou X, Shi D, Zhong R, Ye Z, Ma C, Zhou M, Xi X, Wang L, Chen T, Kwok HF.

Biomolecules. 2019 Jun 25;9(6). pii: E249. doi: 10.3390/biom9060249.

4.

LFB: A Novel Antimicrobial Brevinin-Like Peptide from the Skin Secretion of the Fujian Large Headed Frog, Limnonectes fujianensi.

Li B, Lyu P, Xie S, Qin H, Pu W, Xu H, Chen T, Shaw C, Ge L, Kwok HF.

Biomolecules. 2019 Jun 21;9(6). pii: E242. doi: 10.3390/biom9060242.

5.

Venom Toxins as Potential Targeted Therapies.

Kwok HF.

Toxins (Basel). 2019 Jun 13;11(6). pii: E338. doi: 10.3390/toxins11060338.

6.

Method establishment for upgrading chemical markers in pharmacopoeia to bioactive markers for biological standardization of traditional Chinese medicine.

Lau CB, Yue GG, Lau KM, Chan YY, Shaw PC, Kwok HF, Wong LS.

J Tradit Complement Med. 2018 Sep 12;9(3):179-183. doi: 10.1016/j.jtcme.2018.09.003. eCollection 2019 Jul.

7.

Signaling networks and the feasibility of computational analysis in gastroenteropancreatic neuroendocrine tumors.

Chen P, Wang Q, Xie J, Kwok HF.

Semin Cancer Biol. 2019 Oct;58:80-89. doi: 10.1016/j.semcancer.2019.04.005. Epub 2019 May 1. Review.

PMID:
31054326
8.

Basal but divergent: Clinical implications of differential coagulotoxicity in a clade of Asian vipers.

Debono J, Bos MHA, Coimbra F, Ge L, Frank N, Kwok HF, Fry BG.

Toxicol In Vitro. 2019 Aug;58:195-206. doi: 10.1016/j.tiv.2019.03.038. Epub 2019 Mar 28.

PMID:
30930232
9.

Multiple modulatory activities of Andrographis paniculata on immune responses and xenograft growth in esophageal cancer preclinical models.

Yue GG, Li L, Lee JK, Kwok HF, Wong EC, Li M, Fung KP, Yu J, Chan AW, Chiu PW, Lau CB.

Phytomedicine. 2019 Jul;60:152886. doi: 10.1016/j.phymed.2019.152886. Epub 2019 Mar 12.

PMID:
30910259
10.

Backfilling rolling cycle amplification with enzyme-DNA conjugates on antibody for portable electrochemical immunoassay with glucometer readout.

Ge L, Li B, Xu H, Pu W, Kwok HF.

Biosens Bioelectron. 2019 May 1;132:210-216. doi: 10.1016/j.bios.2019.02.051. Epub 2019 Mar 2.

PMID:
30875633
11.
12.

An innovative anti-cancer Chinese herbal formula exhibited multi-targeted efficacies in metastatic breast cancer mouse model.

Yue GG, Lee JK, Chan BC, Kwok HF, Hoi SW, Sze DM, Fung KP, Leung PC, Lau CB.

Chin Med. 2018 Dec 22;13:64. doi: 10.1186/s13020-018-0222-9. eCollection 2018.

13.

DNA replication licensing proteins: Saints and sinners in cancer.

Mughal MJ, Mahadevappa R, Kwok HF.

Semin Cancer Biol. 2019 Oct;58:11-21. doi: 10.1016/j.semcancer.2018.11.009. Epub 2018 Nov 28. Review.

PMID:
30502375
14.

Rapid discrimination of colon cancer cells with single base mutation in KRAS gene segment using laser tweezers Raman spectroscopy.

Liu M, Liu X, Huang Z, Tang X, Lin X, Xu Y, Chen G, Kwok HF, Lin Y, Feng S.

J Biophotonics. 2019 Mar;12(3):e201800332. doi: 10.1002/jbio.201800332. Epub 2018 Dec 26.

PMID:
30485680
15.

High-throughput Strategy Accelerates the Progress of Marine Anticancer Peptide Drug Development.

Lyu P, Kwok HF.

Recent Pat Anticancer Drug Discov. 2019;14(1):2-4. doi: 10.2174/1574892813999181114152127. No abstract available.

PMID:
30474536
16.

Habu coagulotoxicity: Clinical implications of the functional diversification of Protobothrops snake venoms upon blood clotting factors.

Debono J, Bos MHA, Nouwens A, Ge L, Frank N, Kwok HF, Fry BG.

Toxicol In Vitro. 2019 Mar;55:62-74. doi: 10.1016/j.tiv.2018.11.008. Epub 2018 Nov 22.

PMID:
30471431
17.

Pharmacoinformatic Approach to Explore the Antidote Potential of Phytochemicals on Bungarotoxin from Indian Krait, Bungarus caeruleus.

Rajendran BK, Xavier Suresh M, Bhaskaran SP, Harshitha Y, Gaur U, Kwok HF.

Comput Struct Biotechnol J. 2018 Oct 31;16:450-461. doi: 10.1016/j.csbj.2018.10.005. eCollection 2018.

18.
19.

Targeting PD-L1 Protein: Translation, Modification and Transport.

Wei R, Guo L, Wang Q, Miao J, Kwok HF, Lin Y.

Curr Protein Pept Sci. 2019;20(1):82-91. doi: 10.2174/1389203719666180928105632. Review.

PMID:
30264678
20.

DNA Replication Licensing Protein MCM10 Promotes Tumor Progression and Is a Novel Prognostic Biomarker and Potential Therapeutic Target in Breast Cancer.

Mahadevappa R, Neves H, Yuen SM, Jameel M, Bai Y, Yuen HF, Zhang SD, Zhu Y, Lin Y, Kwok HF.

Cancers (Basel). 2018 Aug 22;10(9). pii: E282. doi: 10.3390/cancers10090282.

21.

Biological Activities of Cationicity-Enhanced and Hydrophobicity-Optimized Analogues of an Antimicrobial Peptide, Dermaseptin-PS3, from the Skin Secretion of Phyllomedusa sauvagii.

Tan Y, Chen X, Ma C, Xi X, Wang L, Zhou M, Burrows JF, Kwok HF, Chen T.

Toxins (Basel). 2018 Aug 7;10(8). pii: E320. doi: 10.3390/toxins10080320.

22.

Triggering of cancer cell cycle arrest by a novel scorpion venom-derived peptide-Gonearrestide.

Li B, Lyu P, Xi X, Ge L, Mahadevappa R, Shaw C, Kwok HF.

J Cell Mol Med. 2018 Sep;22(9):4460-4473. doi: 10.1111/jcmm.13745. Epub 2018 Jul 11.

23.

In vitro and clinical data analysis of Osteopontin as a prognostic indicator in colorectal cancer.

Wei R, Wong JPC, Lyu P, Xi X, Tong O, Zhang SD, Yuen HF, Shirasawa S, Kwok HF.

J Cell Mol Med. 2018 Sep;22(9):4097-4105. doi: 10.1111/jcmm.13686. Epub 2018 May 30.

24.

Does size matter? Venom proteomic and functional comparison between night adder species (Viperidae: Causus) with short and long venom glands.

Coimbra FCP, Dobson J, Zdenek CN, Op den Brouw B, Hamilton B, Debono J, Masci P, Frank N, Ge L, Kwok HF, Fry BG.

Comp Biochem Physiol C Toxicol Pharmacol. 2018 Sep;211:7-14. doi: 10.1016/j.cbpc.2018.05.003. Epub 2018 May 21.

PMID:
29758383
25.

The Roles of Protein Tyrosine Phosphatases in Hepatocellular Carcinoma.

Huang Y, Zhang Y, Ge L, Lin Y, Kwok HF.

Cancers (Basel). 2018 Mar 20;10(3). pii: E82. doi: 10.3390/cancers10030082. Review.

26.

Proteomic and functional variation within black snake venoms (Elapidae: Pseudechis).

Goldenberg J, Cipriani V, Jackson TNW, Arbuckle K, Debono J, Dashevsky D, Panagides N, Ikonomopoulou MP, Koludarov I, Li B, Santana RC, Nouwens A, Jones A, Hay C, Dunstan N, Allen L, Bush B, Miles JJ, Ge L, Kwok HF, Fry BG.

Comp Biochem Physiol C Toxicol Pharmacol. 2018 Feb;205:53-61. doi: 10.1016/j.cbpc.2018.01.001. Epub 2018 Jan 17.

PMID:
29353015
27.

Problem behaviours and psychotropic medication use in intellectual disability: a multinational cross-sectional survey.

Perry BI, Cooray SE, Mendis J, Purandare K, Wijeratne A, Manjubhashini S, Dasari M, Esan F, Gunaratna I, Naseem RA, Hoare S, Chester V, Roy A, Devapriam J, Alexander R, Kwok HF.

J Intellect Disabil Res. 2018 Feb;62(2):140-149. doi: 10.1111/jir.12471.

PMID:
29349928
28.

Venom-based peptide therapy: insights into anti-cancer mechanism.

Ma R, Mahadevappa R, Kwok HF.

Oncotarget. 2017 Oct 11;8(59):100908-100930. doi: 10.18632/oncotarget.21740. eCollection 2017 Nov 21. Review.

29.

Clinical and in vitro analysis of Osteopontin as a prognostic indicator and unveil its potential downstream targets in bladder cancer.

Wong JPC, Wei R, Lyu P, Tong OLH, Zhang SD, Wen Q, Yuen HF, El-Tanani M, Kwok HF.

Int J Biol Sci. 2017 Nov 1;13(11):1373-1386. doi: 10.7150/ijbs.21457. eCollection 2017.

30.

The Roles of microRNAs in Regulating the Expression of PD-1/PD-L1 Immune Checkpoint.

Wang Q, Lin W, Tang X, Li S, Guo L, Lin Y, Kwok HF.

Int J Mol Sci. 2017 Nov 27;18(12). pii: E2540. doi: 10.3390/ijms18122540. Review.

31.

Expression of minichromosome maintenance genes in renal cell carcinoma.

Zhong H, Chen B, Neves H, Xing J, Ye Y, Lin Y, Zhuang G, Zhang SD, Huang J, Kwok HF.

Cancer Manag Res. 2017 Nov 15;9:637-647. doi: 10.2147/CMAR.S146528. eCollection 2017.

32.

β-defensin 1 expression in HCV infected liver/liver cancer: an important role in protecting HCV progression and liver cancer development.

Ling YM, Chen JY, Guo L, Wang CY, Tan WT, Wen Q, Zhang SD, Deng GH, Lin Y, Kwok HF.

Sci Rep. 2017 Oct 17;7(1):13404. doi: 10.1038/s41598-017-13332-0.

33.

Vascular ADAM17 (a Disintegrin and Metalloproteinase Domain 17) Is Required for Angiotensin II/β-Aminopropionitrile-Induced Abdominal Aortic Aneurysm.

Kawai T, Takayanagi T, Forrester SJ, Preston KJ, Obama T, Tsuji T, Kobayashi T, Boyer MJ, Cooper HA, Kwok HF, Hashimoto T, Scalia R, Rizzo V, Eguchi S.

Hypertension. 2017 Nov;70(5):959-963. doi: 10.1161/HYPERTENSIONAHA.117.09822. Epub 2017 Sep 25.

34.

Using Ultra-Performance Liquid Chromatography Quadrupole Time of Flight Mass Spectrometry-Based Chemometrics for the Identification of Anti-angiogenic Biflavonoids from Edible Garcinia Species.

Li P, Yue GG, Kwok HF, Long CL, Lau CB, Kennelly EJ.

J Agric Food Chem. 2017 Sep 27;65(38):8348-8355. doi: 10.1021/acs.jafc.7b02867. Epub 2017 Sep 19.

PMID:
28926234
35.

Venom Peptides: Improving Specificity in Cancer Therapy.

Mahadevappa R, Ma R, Kwok HF.

Trends Cancer. 2017 Sep;3(9):611-614. doi: 10.1016/j.trecan.2017.07.004. Epub 2017 Aug 10. Review.

PMID:
28867164
36.

Osteopontin -- a promising biomarker for cancer therapy.

Wei R, Wong JPC, Kwok HF.

J Cancer. 2017 Jul 15;8(12):2173-2183. doi: 10.7150/jca.20480. eCollection 2017. Review.

37.

Enter the Dragon: The Dynamic and Multifunctional Evolution of Anguimorpha Lizard Venoms.

Koludarov I, Jackson TN, Brouw BOD, Dobson J, Dashevsky D, Arbuckle K, Clemente CJ, Stockdale EJ, Cochran C, Debono J, Stephens C, Panagides N, Li B, Manchadi MR, Violette A, Fourmy R, Hendrikx I, Nouwens A, Clements J, Martelli P, Kwok HF, Fry BG.

Toxins (Basel). 2017 Aug 6;9(8). pii: E242. doi: 10.3390/toxins9080242.

38.

DAPK1 as an independent prognostic marker in liver cancer.

Li L, Guo L, Wang Q, Liu X, Zeng Y, Wen Q, Zhang S, Kwok HF, Lin Y, Liu J.

PeerJ. 2017 Jul 19;5:e3568. doi: 10.7717/peerj.3568. eCollection 2017.

39.

Venom Peptides and Toxins - A Prospective Spearhead in Cancer Treatment.

Wong JPC, Li B, Kwok HF.

Comb Chem High Throughput Screen. 2017;20(5):357-375. doi: 10.2174/1386207320666170621130425. Review.

PMID:
28637411
40.

In sickness and in health: The many roles of the minichromosome maintenance proteins.

Neves H, Kwok HF.

Biochim Biophys Acta Rev Cancer. 2017 Aug;1868(1):295-308. doi: 10.1016/j.bbcan.2017.06.001. Epub 2017 Jun 1. Review.

PMID:
28579200
41.

Anti-tumor effects of a 'human & mouse cross-reactive' anti-ADAM17 antibody in a pancreatic cancer model in vivo.

Ye J, Yuen SM, Murphy G, Xie R, Kwok HF.

Eur J Pharm Sci. 2017 Dec 15;110:62-69. doi: 10.1016/j.ejps.2017.05.057. Epub 2017 May 26.

PMID:
28554668
42.

Coagulating Colubrids: Evolutionary, Pathophysiological and Biodiscovery Implications of Venom Variations between Boomslang (Dispholidus typus) and Twig Snake (Thelotornis mossambicanus).

Debono J, Dobson J, Casewell NR, Romilio A, Li B, Kurniawan N, Mardon K, Weisbecker V, Nouwens A, Kwok HF, Fry BG.

Toxins (Basel). 2017 May 19;9(5). pii: E171. doi: 10.3390/toxins9050171.

43.

Correlation between ontogenetic dietary shifts and venom variation in Australian brown snakes (Pseudonaja).

Cipriani V, Debono J, Goldenberg J, Jackson TNW, Arbuckle K, Dobson J, Koludarov I, Li B, Hay C, Dunstan N, Allen L, Hendrikx I, Kwok HF, Fry BG.

Comp Biochem Physiol C Toxicol Pharmacol. 2017 Jul;197:53-60. doi: 10.1016/j.cbpc.2017.04.007. Epub 2017 Apr 27.

PMID:
28457945
44.

Whole extracts of Radix Achyranthis Bidentatae and Radix Cyathulae promote angiogenesis in human umbilical vein endothelial cells in vitro and in zebrafish in vivo.

Zhou X, Siu WS, Zhang C, Liu CL, Cheng L, Kwok HF, Fung CH, Tam JC, Lau CP, Lau CB, Leung PC, Hung LK, Ko CH.

Exp Ther Med. 2017 Mar;13(3):1032-1038. doi: 10.3892/etm.2017.4053. Epub 2017 Jan 17.

45.

The prognostic significance of Cdc6 and Cdt1 in breast cancer.

Mahadevappa R, Neves H, Yuen SM, Bai Y, McCrudden CM, Yuen HF, Wen Q, Zhang SD, Kwok HF.

Sci Rep. 2017 Apr 20;7(1):985. doi: 10.1038/s41598-017-00998-9.

46.

The prognostic significance of DAPK1 in bladder cancer.

Xie JY, Chen PC, Zhang JL, Gao ZS, Neves H, Zhang SD, Wen Q, Chen WD, Kwok HF, Lin Y.

PLoS One. 2017 Apr 7;12(4):e0175290. doi: 10.1371/journal.pone.0175290. eCollection 2017.

47.

Identification of TWIST-interacting genes in prostate cancer.

Lyu P, Zhang SD, Yuen HF, McCrudden CM, Wen Q, Chan KW, Kwok HF.

Sci China Life Sci. 2017 Apr;60(4):386-396. doi: 10.1007/s11427-016-0262-6. Epub 2017 Jan 22.

PMID:
28120266
48.

Phytochemicals - A Novel and Prominent Source of Anti-cancer Drugs Against Colorectal Cancer.

Mahadevappa R, Kwok HF.

Comb Chem High Throughput Screen. 2017;20(5):376-394. doi: 10.2174/1386207320666170112141833. Review.

PMID:
28078982
49.

CD133 in brain tumor: the prognostic factor.

Li B, McCrudden CM, Yuen HF, Xi X, Lyu P, Chan KW, Zhang SD, Kwok HF.

Oncotarget. 2017 Feb 14;8(7):11144-11159. doi: 10.18632/oncotarget.14406.

50.

Digitoxin synergizes with sorafenib to inhibit hepatocelluar carcinoma cell growth without inhibiting cell migration.

Xiao Y, Yan W, Guo L, Meng C, Li B, Neves H, Chen PC, Li L, Huang Y, Kwok HF, Lin Y.

Mol Med Rep. 2017 Feb;15(2):941-947. doi: 10.3892/mmr.2016.6096. Epub 2016 Dec 30.

PMID:
28035421

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