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Items: 1 to 50 of 158

1.

HHLA2 is expressed in pancreatic and ampullary cancers and increased expression is associated with better post-surgical prognosis.

Boor PPC, Sideras K, Biermann K, Hosein Aziz M, Levink IJM, Mancham S, Erler NS, Tang X, van Eijck CH, Bruno MJ, Sprengers D, Zang X, Kwekkeboom J.

Br J Cancer. 2020 Feb 19. doi: 10.1038/s41416-020-0755-4. [Epub ahead of print]

PMID:
32071413
2.

Antibodies and B cells recognising citrullinated proteins display a broad cross-reactivity towards other post-translational modifications.

Kissel T, Reijm S, Slot LM, Cavallari M, Wortel CM, Vergroesen RD, Stoeken-Rijsbergen G, Kwekkeboom JC, Kampstra A, Levarht E, Drijfhout JW, Bang H, Bonger KM, Janssen G, van Veelen PA, Huizinga T, Scherer HU, Reth M, Toes R.

Ann Rheum Dis. 2020 Apr;79(4):472-480. doi: 10.1136/annrheumdis-2019-216499. Epub 2020 Feb 10.

PMID:
32041746
3.

Mitochondrial Fusion Via OPA1 and MFN1 Supports Liver Tumor Cell Metabolism and Growth.

Li M, Wang L, Wang Y, Zhang S, Zhou G, Lieshout R, Ma B, Liu J, Qu C, Verstegen MMA, Sprengers D, Kwekkeboom J, van der Laan LJW, Cao W, Peppelenbosch MP, Pan Q.

Cells. 2020 Jan 4;9(1). pii: E121. doi: 10.3390/cells9010121.

4.

Complement component C1q is produced by isolated articular chondrocytes.

Lubbers R, van Schaarenburg RA, Kwekkeboom JC, Levarht EWN, Bakker AM, Mahdad R, Monteagudo S, Cherifi C, Lories RJ, Toes REM, Ioan-Facsinay A, Trouw LA.

Osteoarthritis Cartilage. 2019 Oct 18. pii: S1063-4584(19)31228-2. doi: 10.1016/j.joca.2019.09.007. [Epub ahead of print]

PMID:
31634584
5.

Circulating levels of PD-L1 and Galectin-9 are associated with patient survival in surgically treated Hepatocellular Carcinoma independent of their intra-tumoral expression levels.

Sideras K, de Man RA, Harrington SM, Polak WG, Zhou G, Schutz HM, Pedroza-Gonzalez A, Biermann K, Mancham S, Hansen BE, Bart Takkenberg R, van Vuuren AJ, Pan Q, Ijzermans JNM, Sleijfer S, Sprengers D, Dong H, Kwekkeboom J, Bruno MJ.

Sci Rep. 2019 Jul 23;9(1):10677. doi: 10.1038/s41598-019-47235-z.

6.

Reduction of immunosuppressive tumor microenvironment in cholangiocarcinoma by ex vivo targeting immune checkpoint molecules.

Zhou G, Sprengers D, Mancham S, Erkens R, Boor PPC, van Beek AA, Doukas M, Noordam L, Campos Carrascosa L, de Ruiter V, van Leeuwen RWF, Polak WG, de Jonge J, Groot Koerkamp B, van Rosmalen B, van Gulik TM, Verheij J, IJzermans JNM, Bruno MJ, Kwekkeboom J.

J Hepatol. 2019 Oct;71(4):753-762. doi: 10.1016/j.jhep.2019.05.026. Epub 2019 Jun 11.

PMID:
31195061
7.

Immunosuppressive drug withdrawal late after liver transplantation improves the lipid profile and reduces infections.

Duizendstra AA, de Knegt RJ, Betjes MGH, Coenen S, Murad SD, de Man RA, Metselaar HJ, Sprengers D, Litjens NHR, Kwekkeboom J.

Eur J Gastroenterol Hepatol. 2019 Nov;31(11):1444-1451. doi: 10.1097/MEG.0000000000001435.

PMID:
31095525
8.

Characterization of Antigen-Presenting Cell Subsets in Human Liver-Draining Lymph Nodes.

Boor PPC, Bosma BM, Tran KTC, van der Laan LJW, Hagenaars H, IJzermans JNM, Metselaar HJ, Kwekkeboom J.

Front Immunol. 2019 Mar 14;10:441. doi: 10.3389/fimmu.2019.00441. eCollection 2019.

9.

Suppression of Hepatocellular Carcinoma by Mycophenolic Acid in Experimental Models and in Patients.

Chen K, Sheng J, Ma B, Cao W, Hernanda PY, Liu J, Boor PPC, Tjon ASW, Felczak K, Sprengers D, Pankiewicz KW, Metselaar HJ, Ma Z, Kwekkeboom J, Peppelenbosch MP, Pan Q.

Transplantation. 2019 May;103(5):929-937. doi: 10.1097/TP.0000000000002647.

PMID:
30747839
10.

GITR ligation enhances functionality of tumor-infiltrating T cells in hepatocellular carcinoma.

van Beek AA, Zhou G, Doukas M, Boor PPC, Noordam L, Mancham S, Campos Carrascosa L, van der Heide-Mulder M, Polak WG, Ijzermans JNM, Pan Q, Heirman C, Mahne A, Bucktrout SL, Bruno MJ, Sprengers D, Kwekkeboom J.

Int J Cancer. 2019 Aug 15;145(4):1111-1124. doi: 10.1002/ijc.32181. Epub 2019 Feb 27.

11.

Dichotomal functions of phosphorylated and unphosphorylated STAT1 in hepatocellular carcinoma.

Ma B, Chen K, Liu P, Li M, Liu J, Sideras K, Sprengers D, Biermann K, Wang W, IJzermans JNM, Cao W, Kwekkeboom J, Peppelenbosch MP, Pan Q.

J Mol Med (Berl). 2019 Jan;97(1):77-88. doi: 10.1007/s00109-018-1717-7. Epub 2018 Nov 19.

12.

Action and clinical significance of CCAAT/enhancer-binding protein delta in hepatocellular carcinoma.

Liu P, Cao W, Ma B, Li M, Chen K, Sideras K, Duitman JW, Sprengers D, Khe Tran TC, Ijzermans JNM, Biermann K, Verheij J, Spek CA, Kwekkeboom J, Pan Q, Peppelenbosch MP.

Carcinogenesis. 2019 Mar 12;40(1):155-163. doi: 10.1093/carcin/bgy130.

PMID:
30325409
13.

Modeling liver cancer and therapy responsiveness using organoids derived from primary mouse liver tumors.

Cao W, Liu J, Wang L, Li M, Verstegen MMA, Yin Y, Ma B, Chen K, Bolkestein M, Sprengers D, van der Laan LJW, Doukas M, Kwekkeboom J, Smits R, Peppelenbosch MP, Pan Q.

Carcinogenesis. 2019 Mar 12;40(1):145-154. doi: 10.1093/carcin/bgy129.

PMID:
30289434
14.

Blockade of LAG3 enhances responses of tumor-infiltrating T cells in mismatch repair-proficient liver metastases of colorectal cancer.

Zhou G, Noordam L, Sprengers D, Doukas M, Boor PPC, van Beek AA, Erkens R, Mancham S, Grünhagen D, Menon AG, Lange JF, Burger PJWA, Brandt A, Galjart B, Verhoef C, Kwekkeboom J, Bruno MJ.

Oncoimmunology. 2018 Apr 25;7(7):e1448332. doi: 10.1080/2162402X.2018.1448332. eCollection 2018.

15.

Prognostic value of intra-tumoral CD8+ /FoxP3+ lymphocyte ratio in patients with resected colorectal cancer liver metastasis.

Sideras K, Galjart B, Vasaturo A, Pedroza-Gonzalez A, Biermann K, Mancham S, Nigg AL, Hansen BE, Stoop HA, Zhou G, Verhoef C, Sleijfer S, Sprengers D, Kwekkeboom J, Bruno MJ.

J Surg Oncol. 2018 Jul;118(1):68-76. doi: 10.1002/jso.25091. Epub 2018 Jun 7.

16.

Potential Beneficial Effects of Cytomegalovirus Infection after Transplantation.

Litjens NHR, van der Wagen L, Kuball J, Kwekkeboom J.

Front Immunol. 2018 Mar 1;9:389. doi: 10.3389/fimmu.2018.00389. eCollection 2018. Review.

17.

Functional and phenotypical analysis of IL-6-secreting CD4+ T cells in human adipose tissue.

de Jong AJ, Pollastro S, Kwekkeboom JC, Andersen SN, Dorjée AL, Bakker AM, Alzaid F, Soprani A, Nelissen RGHH, Mullers JB, Venteclef N, de Vries N, Kloppenburg M, Toes REM, Ioan-Facsinay A.

Eur J Immunol. 2018 Mar;48(3):471-481. doi: 10.1002/eji.201747037. Epub 2018 Jan 29.

18.

Donor-specific anti-HLA antibodies are not associated with nonanastomotic biliary strictures but both are independent risk factors for graft loss after liver transplantation.

den Dulk AC, Shi X, Verhoeven CJ, Dubbeld J, Claas FHJ, Wolterbeek R, Brand-Schaaf SH, Verspaget HW, Sarasqueta AF, van der Laan LJW, Metselaar HJ, van Hoek B, Kwekkeboom J, Roelen DL.

Clin Transplant. 2018 Feb;32(2). doi: 10.1111/ctr.13163. Epub 2017 Dec 23.

PMID:
29193362
19.

Cross-Tissue Transcriptomic Analysis of Human Secondary Lymphoid Organ-Residing ILC3s Reveals a Quiescent State in the Absence of Inflammation.

Bar-Ephraim YE, Cornelissen F, Papazian N, Konijn T, Hoogenboezem RM, Sanders MA, Westerman BA, Gönültas M, Kwekkeboom J, Den Haan JMM, Reijmers RM, Mebius RE, Cupedo T.

Cell Rep. 2017 Oct 17;21(3):823-833. doi: 10.1016/j.celrep.2017.09.070.

20.

Corrigendum to "MicroRNA profiles in graft preservation solution are predictive of ischemic-type biliary lesions after liver transplantation" [J Hepatol 2013; 59:1231-1238].

Verhoeven CJ, Selten JW, Roest HP, Farid WRR, de Ruiter PE, Hansen BE, de Jonge J, Kwekkeboom J, Metselaar HJ, Tilanus HW, Kazemier G, IJzermans JNM, van der Laan LJW.

J Hepatol. 2017 Sep 27. pii: S0168-8278(17)32279-1. doi: 10.1016/j.jhep.2017.09.001. [Epub ahead of print] No abstract available.

PMID:
28964525
21.

Protective Cytomegalovirus (CMV)-Specific T-Cell Immunity Is Frequent in Kidney Transplant Patients without Serum Anti-CMV Antibodies.

Litjens NHR, Huang L, Dedeoglu B, Meijers RWJ, Kwekkeboom J, Betjes MGH.

Front Immunol. 2017 Sep 12;8:1137. doi: 10.3389/fimmu.2017.01137. eCollection 2017.

22.

Lack of high BMI-related features in adipocytes and inflammatory cells in the infrapatellar fat pad (IFP).

de Jong AJ, Klein-Wieringa IR, Andersen SN, Kwekkeboom JC, Herb-van Toorn L, de Lange-Brokaar BJE, van Delft D, Garcia J, Wei W, van der Heide HJL, Bastiaansen-Jenniskens YM, van Osch GJVM, Zuurmond AM, Stojanovic-Susulic V, Nelissen RGHH, Toes REM, Kloppenburg M, Ioan-Facsinay A.

Arthritis Res Ther. 2017 Aug 11;19(1):186. doi: 10.1186/s13075-017-1395-9.

23.

Inflammatory features of infrapatellar fat pad in rheumatoid arthritis versus osteoarthritis reveal mostly qualitative differences.

de Jong AJ, Klein-Wieringa IR, Kwekkeboom JC, Toes REM, Kloppenburg M, Ioan-Facsinay A.

Ann Rheum Dis. 2018 Jul;77(7):1088-1090. doi: 10.1136/annrheumdis-2017-211673. Epub 2017 Aug 5. No abstract available.

PMID:
28780513
24.

Dynamics of Proliferative and Quiescent Stem Cells in Liver Homeostasis and Injury.

Cao W, Chen K, Bolkestein M, Yin Y, Verstegen MMA, Bijvelds MJC, Wang W, Tuysuz N, Ten Berge D, Sprengers D, Metselaar HJ, van der Laan LJW, Kwekkeboom J, Smits R, Peppelenbosch MP, Pan Q.

Gastroenterology. 2017 Oct;153(4):1133-1147. doi: 10.1053/j.gastro.2017.07.006. Epub 2017 Jul 14.

PMID:
28716722
25.

Antibodies Against Immune Checkpoint Molecules Restore Functions of Tumor-Infiltrating T Cells in Hepatocellular Carcinomas.

Zhou G, Sprengers D, Boor PPC, Doukas M, Schutz H, Mancham S, Pedroza-Gonzalez A, Polak WG, de Jonge J, Gaspersz M, Dong H, Thielemans K, Pan Q, IJzermans JNM, Bruno MJ, Kwekkeboom J.

Gastroenterology. 2017 Oct;153(4):1107-1119.e10. doi: 10.1053/j.gastro.2017.06.017. Epub 2017 Jun 23.

PMID:
28648905
26.

Tumor cell expression of immune inhibitory molecules and tumor-infiltrating lymphocyte count predict cancer-specific survival in pancreatic and ampullary cancer.

Sideras K, Biermann K, Yap K, Mancham S, Boor PPC, Hansen BE, Stoop HJA, Peppelenbosch MP, van Eijck CH, Sleijfer S, Kwekkeboom J, Bruno MJ.

Int J Cancer. 2017 Aug 1;141(3):572-582. doi: 10.1002/ijc.30760. Epub 2017 May 19.

27.

Unphosphorylated ISGF3 drives constitutive expression of interferon-stimulated genes to protect against viral infections.

Wang W, Yin Y, Xu L, Su J, Huang F, Wang Y, Boor PPC, Chen K, Wang W, Cao W, Zhou X, Liu P, van der Laan LJW, Kwekkeboom J, Peppelenbosch MP, Pan Q.

Sci Signal. 2017 Apr 25;10(476). pii: eaah4248. doi: 10.1126/scisignal.aah4248.

PMID:
28442624
28.

PD-L1, Galectin-9 and CD8+ tumor-infiltrating lymphocytes are associated with survival in hepatocellular carcinoma.

Sideras K, Biermann K, Verheij J, Takkenberg BR, Mancham S, Hansen BE, Schutz HM, de Man RA, Sprengers D, Buschow SI, Verseput MC, Boor PP, Pan Q, van Gulik TM, Terkivatan T, Ijzermans JN, Beuers UH, Sleijfer S, Bruno MJ, Kwekkeboom J.

Oncoimmunology. 2017 Jan 3;6(2):e1273309. doi: 10.1080/2162402X.2016.1273309. eCollection 2017.

29.

Targeted lipidomics reveals activation of resolution pathways in knee osteoarthritis in humans.

Jónasdóttir HS, Brouwers H, Kwekkeboom JC, van der Linden HMJ, Huizinga T, Kloppenburg M, Toes REM, Giera M, Ioan-Facsinay A.

Osteoarthritis Cartilage. 2017 Jul;25(7):1150-1160. doi: 10.1016/j.joca.2017.01.018. Epub 2017 Feb 8.

30.

Immunomodulation by hyperimmunoglobulins after solid organ transplantation: Beyond prevention of viral infection.

van Gent R, Metselaar HJ, Kwekkeboom J.

Transplant Rev (Orlando). 2017 Apr;31(2):78-86. doi: 10.1016/j.trre.2017.01.001. Epub 2017 Jan 19. Review.

PMID:
28131494
31.

JAK-inhibitor tofacitinib suppresses interferon alfa production by plasmacytoid dendritic cells and inhibits arthrogenic and antiviral effects of interferon alfa.

Boor PPC, de Ruiter PE, Asmawidjaja PS, Lubberts E, van der Laan LJW, Kwekkeboom J.

Transl Res. 2017 Oct;188:67-79. doi: 10.1016/j.trsl.2016.11.006. Epub 2016 Nov 20.

PMID:
27931982
32.

Reply to: Comment on 'Tumour antigen expression in hepatocellular carcinoma in a low-endemic western area'.

Sideras K, J Bruno M, Kwekkeboom J.

Br J Cancer. 2016 May 10;114(10):e2. doi: 10.1038/bjc.2015.442. Epub 2016 Apr 14. No abstract available.

33.

Inflammatory Cells in Patients with Endstage Knee Osteoarthritis: A Comparison between the Synovium and the Infrapatellar Fat Pad.

Klein-Wieringa IR, de Lange-Brokaar BJ, Yusuf E, Andersen SN, Kwekkeboom JC, Kroon HM, van Osch GJ, Zuurmond AM, Stojanovic-Susulic V, Nelissen RG, Toes RE, Kloppenburg M, Ioan-Facsinay A.

J Rheumatol. 2016 Apr;43(4):771-8. doi: 10.3899/jrheum.151068. Epub 2016 Mar 15.

PMID:
26980579
34.

Counter-regulation of rejection activity against human liver grafts by donor PD-L1 and recipient PD-1 interaction.

Shi XL, Mancham S, Hansen BE, de Knegt RJ, de Jonge J, van der Laan LJ, Rivadeneira F, Metselaar HJ, Kwekkeboom J.

J Hepatol. 2016 Jun;64(6):1274-82. doi: 10.1016/j.jhep.2016.02.034. Epub 2016 Mar 3.

PMID:
26941095
35.

Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels.

Kilpeläinen TO, Carli JF, Skowronski AA, Sun Q, Kriebel J, Feitosa MF, Hedman ÅK, Drong AW, Hayes JE, Zhao J, Pers TH, Schick U, Grarup N, Kutalik Z, Trompet S, Mangino M, Kristiansson K, Beekman M, Lyytikäinen LP, Eriksson J, Henneman P, Lahti J, Tanaka T, Luan J, Del Greco M F, Pasko D, Renström F, Willems SM, Mahajan A, Rose LM, Guo X, Liu Y, Kleber ME, Pérusse L, Gaunt T, Ahluwalia TS, Ju Sung Y, Ramos YF, Amin N, Amuzu A, Barroso I, Bellis C, Blangero J, Buckley BM, Böhringer S, I Chen YD, de Craen AJ, Crosslin DR, Dale CE, Dastani Z, Day FR, Deelen J, Delgado GE, Demirkan A, Finucane FM, Ford I, Garcia ME, Gieger C, Gustafsson S, Hallmans G, Hankinson SE, Havulinna AS, Herder C, Hernandez D, Hicks AA, Hunter DJ, Illig T, Ingelsson E, Ioan-Facsinay A, Jansson JO, Jenny NS, Jørgensen ME, Jørgensen T, Karlsson M, Koenig W, Kraft P, Kwekkeboom J, Laatikainen T, Ladwig KH, LeDuc CA, Lowe G, Lu Y, Marques-Vidal P, Meisinger C, Menni C, Morris AP, Myers RH, Männistö S, Nalls MA, Paternoster L, Peters A, Pradhan AD, Rankinen T, Rasmussen-Torvik LJ, Rathmann W, Rice TK, Brent Richards J, Ridker PM, Sattar N, Savage DB, Söderberg S, Timpson NJ, Vandenput L, van Heemst D, Uh HW, Vohl MC, Walker M, Wichmann HE, Widén E, Wood AR, Yao J, Zeller T, Zhang Y, Meulenbelt I, Kloppenburg M, Astrup A, Sørensen TI, Sarzynski MA, Rao DC, Jousilahti P, Vartiainen E, Hofman A, Rivadeneira F, Uitterlinden AG, Kajantie E, Osmond C, Palotie A, Eriksson JG, Heliövaara M, Knekt PB, Koskinen S, Jula A, Perola M, Huupponen RK, Viikari JS, Kähönen M, Lehtimäki T, Raitakari OT, Mellström D, Lorentzon M, Casas JP, Bandinelli S, März W, Isaacs A, van Dijk KW, van Duijn CM, Harris TB, Bouchard C, Allison MA, Chasman DI, Ohlsson C, Lind L, Scott RA, Langenberg C, Wareham NJ, Ferrucci L, Frayling TM, Pramstaller PP, Borecki IB, Waterworth DM, Bergmann S, Waeber G, Vollenweider P, Vestergaard H, Hansen T, Pedersen O, Hu FB, Eline Slagboom P, Grallert H, Spector TD, Jukema JW, Klein RJ, Schadt EE, Franks PW, Lindgren CM, Leibel RL, Loos RJ.

Nat Commun. 2016 Feb 1;7:10494. doi: 10.1038/ncomms10494.

36.

Reply to "Cytomegalovirus-Induced γδ T Cells During Rejection: An Ambivalent T Cell".

Shi XL, Kwekkeboom J.

Am J Transplant. 2016 Jan;16(1):370. doi: 10.1111/ajt.13566. No abstract available.

37.

GITR engagement in combination with CTLA-4 blockade completely abrogates immunosuppression mediated by human liver tumor-derived regulatory T cells ex vivo.

Pedroza-Gonzalez A, Zhou G, Singh SP, Boor PP, Pan Q, Grunhagen D, de Jonge J, Tran TK, Verhoef C, IJzermans JN, Janssen H, Biermann K, Kwekkeboom J, Sprengers D.

Oncoimmunology. 2015 May 29;4(12):e1051297. eCollection 2015 Dec.

38.

Differential Sensitivities of Fast- and Slow-Cycling Cancer Cells to Inosine Monophosphate Dehydrogenase 2 Inhibition by Mycophenolic Acid.

Chen K, Cao W, Li J, Sprengers D, Y Hernanda P, Kong X, Jw van der Laan L, Man K, Kwekkeboom J, J Metselaar H, P Peppelenbosch M, Pan Q.

Mol Med. 2016 Jan;21(1):792-802. doi: 10.2119/molmed.2015.00126. Epub 2015 Oct 13.

39.

Polarized release of hepatic microRNAs into bile and serum in response to cellular injury and impaired liver function.

Verhoeven CJ, Farid WR, Roest HP, Ramakrishnaiah V, de Ruiter PE, de Jonge J, Kwekkeboom J, Metselaar HJ, Tilanus HW, Kazemier G, Ijzermans JN, van der Laan LJ.

Liver Int. 2016 Jun;36(6):883-92. doi: 10.1111/liv.12955. Epub 2015 Sep 28.

PMID:
26344705
40.

Prednisolone does not affect direct-acting antivirals against hepatitis C, but inhibits interferon-alpha production by plasmacytoid dendritic cells.

de Ruiter PE, Boor PP, de Jonge J, Metselaar HJ, Tilanus HW, Ijzermans JN, Kwekkeboom J, van der Laan LJ.

Transpl Infect Dis. 2015 Oct;17(5):707-15. doi: 10.1111/tid.12430. Epub 2015 Sep 26.

PMID:
26250892
41.

Cytomegalovirus-Induced Expression of CD244 after Liver Transplantation Is Associated with CD8+ T Cell Hyporesponsiveness to Alloantigen.

de Mare-Bredemeijer EL, Shi XL, Mancham S, van Gent R, van der Heide-Mulder M, de Boer R, Heemskerk MH, de Jonge J, van der Laan LJ, Metselaar HJ, Kwekkeboom J.

J Immunol. 2015 Aug 15;195(4):1838-48. doi: 10.4049/jimmunol.1500440. Epub 2015 Jul 13.

42.

Tumor-infiltrating plasmacytoid dendritic cells promote immunosuppression by Tr1 cells in human liver tumors.

Pedroza-Gonzalez A, Zhou G, Vargas-Mendez E, Boor PP, Mancham S, Verhoef C, Polak WG, Grünhagen D, Pan Q, Janssen H, Garcia-Romo GS, Biermann K, Tjwa ET, IJzermans JN, Kwekkeboom J, Sprengers D.

Oncoimmunology. 2015 Mar 19;4(6):e1008355. eCollection 2015 Jun.

43.

Tumour antigen expression in hepatocellular carcinoma in a low-endemic western area.

Sideras K, Bots SJ, Biermann K, Sprengers D, Polak WG, IJzermans JN, de Man RA, Pan Q, Sleijfer S, Bruno MJ, Kwekkeboom J.

Br J Cancer. 2015 Jun 9;112(12):1911-20. doi: 10.1038/bjc.2015.92.

44.

Differences in Anti-Inflammatory Actions of Intravenous Immunoglobulin between Mice and Men: More than Meets the Eye.

Tjon AS, van Gent R, Geijtenbeek TB, Kwekkeboom J.

Front Immunol. 2015 Apr 28;6:197. doi: 10.3389/fimmu.2015.00197. eCollection 2015. Review.

45.

Prominent HLA-G Expression in Liver Disease But Not After Liver Transplantation.

Moroso V, van Cranenbroek B, Mancham S, Sideras K, Boor PP, Biermann K, de Vogel L, de Knegt RJ, van der Eijk A, van der Laan LJ, de Jonge J, Metselaar HJ, Joosten I, Kwekkeboom J.

Transplantation. 2015 Dec;99(12):2514-22. doi: 10.1097/TP.0000000000000761.

PMID:
25961490
46.

CMV Primary Infection Is Associated With Donor-Specific T Cell Hyporesponsiveness and Fewer Late Acute Rejections After Liver Transplantation.

Shi XL, de Mare-Bredemeijer EL, Tapirdamaz Ö, Hansen BE, van Gent R, van Campenhout MJ, Mancham S, Litjens NH, Betjes MG, van der Eijk AA, Xia Q, van der Laan LJ, de Jonge J, Metselaar HJ, Kwekkeboom J.

Am J Transplant. 2015 Sep;15(9):2431-42. doi: 10.1111/ajt.13288. Epub 2015 May 5.

47.

The IVIg dilemma: a way out?

van Gent R, Kwekkeboom J.

Am J Transplant. 2015 Jun;15(6):1725-6. doi: 10.1111/ajt.13253. Epub 2015 Apr 1. No abstract available.

48.

Human graft-derived mesenchymal stromal cells potently suppress alloreactive T-cell responses.

de Mare-Bredemeijer EL, Mancham S, Verstegen MM, de Ruiter PE, van Gent R, O'Neill D, Tilanus HW, Metselaar HJ, de Jonge J, Kwekkeboom J, Hall SR, van der Laan LJ.

Stem Cells Dev. 2015 Jun 15;24(12):1436-47. doi: 10.1089/scd.2014.0485. Epub 2015 Apr 28.

PMID:
25744002
49.

SMAD4 exerts a tumor-promoting role in hepatocellular carcinoma.

Hernanda PY, Chen K, Das AM, Sideras K, Wang W, Li J, Cao W, Bots SJ, Kodach LL, de Man RA, Ijzermans JN, Janssen HL, Stubbs AP, Sprengers D, Bruno MJ, Metselaar HJ, ten Hagen TL, Kwekkeboom J, Peppelenbosch MP, Pan Q.

Oncogene. 2015 Sep 24;34(39):5055-68. doi: 10.1038/onc.2014.425. Epub 2014 Dec 22.

PMID:
25531314
50.

Kupffer cells interact with hepatitis B surface antigen in vivo and in vitro, leading to proinflammatory cytokine production and natural killer cell function.

Boltjes A, van Montfoort N, Biesta PJ, Op den Brouw ML, Kwekkeboom J, van der Laan LJ, Janssen HL, Boonstra A, Woltman AM.

J Infect Dis. 2015 Apr 15;211(8):1268-78. doi: 10.1093/infdis/jiu599. Epub 2014 Oct 31.

PMID:
25362194

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