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Items: 38


Cell surface α2,3-linked sialic acid facilitates Zika virus internalization.

Tan CW, Huan Hor CH, Kwek SS, Tee HK, Sam IC, Goh ELK, Ooi EE, Chan YF, Wang LF.

Emerg Microbes Infect. 2019;8(1):426-437. doi: 10.1080/22221751.2019.1590130.


Clonal Deletion of Tumor-Specific T Cells by Interferon-γ Confers Therapeutic Resistance to Combination Immune Checkpoint Blockade.

Pai CS, Huang JT, Lu X, Simons DM, Park C, Chang A, Tamaki W, Liu E, Roybal KT, Seagal J, Chen M, Hagihara K, Wei XX, DuPage M, Kwek SS, Oh DY, Daud A, Tsai KK, Wu C, Zhang L, Fasso M, Sachidanandam R, Jayaprakash A, Lin I, Casbon AJ, Kinsbury GA, Fong L.

Immunity. 2019 Feb 19;50(2):477-492.e8. doi: 10.1016/j.immuni.2019.01.006. Epub 2019 Feb 5.


Development of a Collaborative Algorithm for the Management of Type 2 Diabetes during Ramadan: An Anchor on Empowerment.

Lum ZK, See Toh WY, Lim SM, Rusli KDB, Abdul Shakoor SAKK, Tsou KYK, Chew DEK, Dalan R, Kwek SC, Othman N, Lian JX, Lee JY.

Diabetes Technol Ther. 2018 Oct;20(10):698-703. doi: 10.1089/dia.2018.0159. Epub 2018 Sep 6.


Single-cell RNA sequencing reveals gene expression signatures of breast cancer-associated endothelial cells.

Sun Z, Wang CY, Lawson DA, Kwek S, Velozo HG, Owyong M, Lai MD, Fong L, Wilson M, Su H, Werb Z, Cooke DL.

Oncotarget. 2017 Dec 29;9(13):10945-10961. doi: 10.18632/oncotarget.23760. eCollection 2018 Feb 16.


A systematic approach to the development of a safe live attenuated Zika vaccine.

Kwek SS, Watanabe S, Chan KR, Ong EZ, Tan HC, Ng WC, Nguyen MTX, Gan ES, Zhang SL, Chan KWK, Tan JH, Sessions OM, Manuel M, Pompon J, Chua C, Hazirah S, Tryggvason K, Vasudevan SG, Ooi EE.

Nat Commun. 2018 Mar 12;9(1):1031. doi: 10.1038/s41467-018-03337-2.


Predictors of responses to immune checkpoint blockade in advanced melanoma.

Jacquelot N, Roberti MP, Enot DP, Rusakiewicz S, Ternès N, Jegou S, Woods DM, Sodré AL, Hansen M, Meirow Y, Sade-Feldman M, Burra A, Kwek SS, Flament C, Messaoudene M, Duong CPM, Chen L, Kwon BS, Anderson AC, Kuchroo VK, Weide B, Aubin F, Borg C, Dalle S, Beatrix O, Ayyoub M, Balme B, Tomasic G, Di Giacomo AM, Maio M, Schadendorf D, Melero I, Dréno B, Khammari A, Dummer R, Levesque M, Koguchi Y, Fong L, Lotem M, Baniyash M, Schmidt H, Svane IM, Kroemer G, Marabelle A, Michiels S, Cavalcanti A, Smyth MJ, Weber JS, Eggermont AM, Zitvogel L.

Nat Commun. 2017 Sep 19;8(1):592. doi: 10.1038/s41467-017-00608-2.


Systemic Immunity Is Required for Effective Cancer Immunotherapy.

Spitzer MH, Carmi Y, Reticker-Flynn NE, Kwek SS, Madhireddy D, Martins MM, Gherardini PF, Prestwood TR, Chabon J, Bendall SC, Fong L, Nolan GP, Engleman EG.

Cell. 2017 Jan 26;168(3):487-502.e15. doi: 10.1016/j.cell.2016.12.022. Epub 2017 Jan 19.


Immune Toxicities Elicted by CTLA-4 Blockade in Cancer Patients Are Associated with Early Diversification of the T-cell Repertoire.

Oh DY, Cham J, Zhang L, Fong G, Kwek SS, Klinger M, Faham M, Fong L.

Cancer Res. 2017 Mar 15;77(6):1322-1330. doi: 10.1158/0008-5472.CAN-16-2324. Epub 2016 Dec 28.


Systemic GM-CSF Recruits Effector T Cells into the Tumor Microenvironment in Localized Prostate Cancer.

Wei XX, Chan S, Kwek S, Lewis J, Dao V, Zhang L, Cooperberg MR, Ryan CJ, Lin AM, Friedlander TW, Rini B, Kane C, Simko JP, Carroll PR, Small EJ, Fong L.

Cancer Immunol Res. 2016 Nov;4(11):948-958. Epub 2016 Sep 29.


GM-CSF and ipilimumab therapy in metastatic melanoma: Clinical outcomes and immunologic responses.

Kwek SS, Kahn J, Greaney SK, Lewis J, Cha E, Zhang L, Weber RW, Leonard L, Markovic SN, Fong L, Spitler LE.

Oncoimmunology. 2015 Oct 29;5(4):e1101204. eCollection 2016 Apr.


Ministry of Health Clinical Practice Guidelines: Anxiety Disorders.

Lim L, Chan HN, Chew PH, Chua SM, Ho C, Kwek SK, Lee TS, Loh P, Lum A, Tan YH, Wan YM, Woo M, Yap HL.

Singapore Med J. 2015 Jun;56(6):310-5; quiz 316. doi: 10.11622/smedj.2015088.


Preexisting Levels of CD4 T Cells Expressing PD-1 Are Related to Overall Survival in Prostate Cancer Patients Treated with Ipilimumab.

Kwek SS, Lewis J, Zhang L, Weinberg V, Greaney SK, Harzstark AL, Lin AM, Ryan CJ, Small EJ, Fong L.

Cancer Immunol Res. 2015 Sep;3(9):1008-16. doi: 10.1158/2326-6066.CIR-14-0227. Epub 2015 May 12.


Nanoscratch testing for the assessment of enamel demineralization under conditions simulating wine erosion.

Kwek SX, Mian M, Hall C, Xie Z, Yong R, Kaidonis J, Townsend GC, Ranjitkar S.

Aust Dent J. 2015 Mar;60(1):12-7. doi: 10.1111/adj.12277.


The changing face of personhood at the end of life: The ring theory of personhood.

Krishna LK, Kwek SY.

Palliat Support Care. 2015 Aug;13(4):1123-9. doi: 10.1017/S1478951514000686. Epub 2014 Jul 3.


Frequently asked questions in allergy practice.

Tan XX, Xie P, Kwek JL, Kwek SY, Yang Z, Soon W, Leong JL, Wang DY.

Asia Pac Allergy. 2014 Jan;4(1):48-53. doi: 10.5415/apallergy.2014.4.1.48. Epub 2014 Jan 31.


Diversity of antigen-specific responses induced in vivo with CTLA-4 blockade in prostate cancer patients.

Kwek SS, Dao V, Roy R, Hou Y, Alajajian D, Simko JP, Small EJ, Fong L.

J Immunol. 2012 Oct 1;189(7):3759-66. Epub 2012 Sep 5.


Unmasking the immune recognition of prostate cancer with CTLA4 blockade.

Kwek SS, Cha E, Fong L.

Nat Rev Cancer. 2012 Mar 1;12(4):289-97. doi: 10.1038/nrc3223. Review.


The B-cell specific transcription factor, Oct-2, promotes Epstein-Barr virus latency by inhibiting the viral immediate-early protein, BZLF1.

Robinson AR, Kwek SS, Kenney SC.

PLoS Pathog. 2012 Feb;8(2):e1002516. doi: 10.1371/journal.ppat.1002516. Epub 2012 Feb 9.


Ministry of Health clinical practice guidelines: depression.

Chua HC, Chan LL, Chee KS, Chen YH, Chin SA, Chua PL, Fones SL, Fung D, Khoo CL, Kwek SK, Lim EC, Ling J, Poh P, Sim K, Tan BL, Tan CH, Tan LL, Tan YH, Tay WK, Yeo C, Su HC; Singapore Ministry of Health.

Singapore Med J. 2012 Feb;53(2):137-43; quiz 144.


Ministry of Health clinical practice guidelines: schizophrenia.

Verma S, Chan LL, Chee KS, Chen H, Chin SA, Chong SA, Chua W, Fones C, Fung D, Khoo CL, Kwek SK, Ling J, Poh P, Sim K, Tan BL, Tan C, Tan CH, Tan LL, Tay WK; MOH Clinical Practice Guidelines Workgroup on Schizophrenia.

Singapore Med J. 2011 Jul;52(7):521-5; quiz 526.


Cellular transcription factor Oct-1 interacts with the Epstein-Barr virus BRLF1 protein to promote disruption of viral latency.

Robinson AR, Kwek SS, Hagemeier SR, Wille CK, Kenney SC.

J Virol. 2011 Sep;85(17):8940-53. doi: 10.1128/JVI.00569-11. Epub 2011 Jun 22.


Onset of psoriasis during therapy with fluoxetine.

Tan Pei Lin L, Kwek SK.

Gen Hosp Psychiatry. 2010 Jul-Aug;32(4):446.e9-446.e10. doi: 10.1016/j.genhosppsych.2009.08.008. Epub 2009 Sep 24.


An aberrant prostate antigen-specific immune response causes prostatitis in mice and is associated with chronic prostatitis in humans.

Hou Y, DeVoss J, Dao V, Kwek S, Simko JP, McNeel DG, Anderson MS, Fong L.

J Clin Invest. 2009 Jul;119(7):2031-41. doi: 10.1172/JCI38332.


Co-amplified genes at 8p12 and 11q13 in breast tumors cooperate with two major pathways in oncogenesis.

Kwek SS, Roy R, Zhou H, Climent J, Martinez-Climent JA, Fridlyand J, Albertson DG.

Oncogene. 2009 Apr 30;28(17):1892-903. doi: 10.1038/onc.2009.34. Epub 2009 Mar 30.


Potentiating endogenous antitumor immunity to prostate cancer through combination immunotherapy with CTLA4 blockade and GM-CSF.

Fong L, Kwek SS, O'Brien S, Kavanagh B, McNeel DG, Weinberg V, Lin AM, Rosenberg J, Ryan CJ, Rini BI, Small EJ.

Cancer Res. 2009 Jan 15;69(2):609-15. doi: 10.1158/0008-5472.CAN-08-3529.


Genome position and gene amplification.

Gajduskova P, Snijders AM, Kwek S, Roydasgupta R, Fridlyand J, Tokuyasu T, Pinkel D, Albertson DG.

Genome Biol. 2007;8(6):R120.


The origin of chromosome imbalances in neuroblastoma.

Stallings RL, Yoon K, Kwek S, Ko D.

Cancer Genet Cytogenet. 2007 Jul 1;176(1):28-34.


Quality of life and psychological status in survivors of severe acute respiratory syndrome at 3 months postdischarge.

Kwek SK, Chew WM, Ong KC, Ng AW, Lee LS, Kaw G, Leow MK.

J Psychosom Res. 2006 May;60(5):513-9.


1-year pulmonary function and health status in survivors of severe acute respiratory syndrome.

Ong KC, Ng AW, Lee LS, Kaw G, Kwek SK, Leow MK, Earnest A.

Chest. 2005 Sep;128(3):1393-400.


Pulmonary function and exercise capacity in survivors of severe acute respiratory syndrome.

Ong KC, Ng AW, Lee LS, Kaw G, Kwek SK, Leow MK, Earnest A.

Eur Respir J. 2004 Sep;24(3):436-42.


Apoptosis inhibitor as a suppressor of tumor progression: expression of Bcl-2 eliminates selective advantages for p53-deficient cells in the tumor.

Gurova KV, Kwek SS, Koman IE, Komarov AP, Kandel E, Nikiforov MA, Gudkov AV.

Cancer Biol Ther. 2002 Jan-Feb;1(1):39-44.


Functional analysis and intracellular localization of p53 modified by SUMO-1.

Kwek SS, Derry J, Tyner AL, Shen Z, Gudkov AV.

Oncogene. 2001 May 3;20(20):2587-99.


p53 is involved in tumor necrosis factor-alpha-induced apoptosis in the human prostatic carcinoma cell line LNCaP.

Rokhlin OW, Gudkov AV, Kwek S, Glover RA, Gewies AS, Cohen MB.

Oncogene. 2000 Apr 6;19(15):1959-68.


Structure and regulation of the mouse ing1 gene. Three alternative transcripts encode two phd finger proteins that have opposite effects on p53 function.

Zeremski M, Hill JE, Kwek SS, Grigorian IA, Gurova KV, Garkavtsev IV, Diatchenko L, Koonin EV, Gudkov AV.

J Biol Chem. 1999 Nov 5;274(45):32172-81.


Suppression of apoptosis by bcl-2 does not prevent p53-mediated control of experimental metastasis and anchorage dependence.

Nikiforov MA, Kwek SS, Mehta R, Artwohl JE, Lowe SW, Gupta TD, Deichman GI, Gudkov AV.

Oncogene. 1997 Dec 18;15(25):3007-12.

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