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Items: 1 to 50 of 180

1.

New molecular and therapeutic insights into canine diffuse large B cell lymphoma elucidates the role of the dog as a model for human disease.

Aresu L, Ferraresso S, Marconato L, Cascione L, Napoli S, Gaudio E, Kwee I, Tarantelli C, Testa A, Maniaci C, Ciulli A, Hillmann P, Bohnacker T, Wymann MP, Comazzi S, Milan M, Riondato F, Dalla Rovere G, Giantin M, Giannuzzi D, Bertoni F.

Haematologica. 2018 Dec 13. pii: haematol.2018.207027. doi: 10.3324/haematol.2018.207027. [Epub ahead of print]

2.

Correction to: cuRnet: an R package for graph traversing on GPU.

Bonnici V, Busato F, Aldegheri S, Akhmedov M, Cascione L, Carmena AA, Bertoni F, Bombieri N, Kwee I, Giugno R.

BMC Bioinformatics. 2018 Nov 27;19(1):456. doi: 10.1186/s12859-018-2484-8.

3.

cuRnet: an R package for graph traversing on GPU.

Bonnici V, Busato F, Aldegheri S, Akhmedov M, Cascione L, Carmena AA, Bertoni F, Bombieri N, Kwee I, Giugno R.

BMC Bioinformatics. 2018 Oct 15;19(Suppl 10):356. doi: 10.1186/s12859-018-2310-3. Erratum in: BMC Bioinformatics. 2018 Nov 27;19(1):456.

4.

BET bromodomain inhibitor birabresib in mantle cell lymphoma: in vivo activity and identification of novel combinations to overcome adaptive resistance.

Tarantelli C, Bernasconi E, Gaudio E, Cascione L, Restelli V, Arribas AJ, Spriano F, Rinaldi A, Mensah AA, Kwee I, Ponzoni M M.D, Zucca E, Carrassa L, Riveiro ME, Rezai K, Stathis A, Cvitkovic E, Bertoni F.

ESMO Open. 2018 Sep 26;3(6):e000387. doi: 10.1136/esmoopen-2018-000387. eCollection 2018.

5.

Population-based outcome analysis of diffuse large B-cell lymphoma in people living with HIV infection and competent individuals.

Conconi A, Zucca E, Margiotta-Casaluci G, Darling K, Hasse B, Battegay M, Staehelin C, Novak U, Schmid P, Scherrer A, Dirnhofer S, Kwee I, Nassi L, Cavalli F, Gaidano G, Bertoni F, Bernasconi E; Swiss HIV Cohort study (SHCS).

Hematol Oncol. 2018 Dec;36(5):757-764. doi: 10.1002/hon.2536. Epub 2018 Aug 16.

PMID:
30113708
6.

Bromodomain and extra-terminal domain inhibition modulates the expression of pathologically relevant microRNAs in diffuse large B-cell lymphoma.

Mensah AA, Cascione L, Gaudio E, Tarantelli C, Bomben R, Bernasconi E, Zito D, Lampis A, Hahne JC, Rinaldi A, Stathis A, Zucca E, Kwee I, Gattei V, Valeri N, Riveiro ME, Bertoni F.

Haematologica. 2018 Aug 3. pii: haematol.2018.191684. doi: 10.3324/haematol.2018.191684. [Epub ahead of print]

7.

Fluid Dynamics Inside the Brain Barrier: Current Concept of Interstitial Flow, Glymphatic Flow, and Cerebrospinal Fluid Circulation in the Brain.

Nakada T, Kwee IL.

Neuroscientist. 2018 May 1:1073858418775027. doi: 10.1177/1073858418775027. [Epub ahead of print]

PMID:
29799313
8.

Aquaporin-4 facilitator TGN-073 promotes interstitial fluid circulation within the blood-brain barrier: [17O]H2O JJVCPE MRI study.

Huber VJ, Igarashi H, Ueki S, Kwee IL, Nakada T.

Neuroreport. 2018 Jun 13;29(9):697-703. doi: 10.1097/WNR.0000000000000990.

9.

Musical pitch classes have rainbow hues in pitch class-color synesthesia.

Itoh K, Sakata H, Kwee IL, Nakada T.

Sci Rep. 2017 Dec 19;7(1):17781. doi: 10.1038/s41598-017-18150-y.

10.

Inferior colliculus syndrome: Clinical magnetic resonance microscopy anatomic analysis on a 7 T system.

Kwee IL, Matsuzawa H, Nakada K, Fujii Y, Nakada T.

SAGE Open Med Case Rep. 2017 Dec 5;5:2050313X17745209. doi: 10.1177/2050313X17745209. eCollection 2017.

11.

PQR309 Is a Novel Dual PI3K/mTOR Inhibitor with Preclinical Antitumor Activity in Lymphomas as a Single Agent and in Combination Therapy.

Tarantelli C, Gaudio E, Arribas AJ, Kwee I, Hillmann P, Rinaldi A, Cascione L, Spriano F, Bernasconi E, Guidetti F, Carrassa L, Pittau RB, Beaufils F, Ritschard R, Rageot D, Sele A, Dossena B, Rossi FM, Zucchetto A, Taborelli M, Gattei V, Rossi D, Stathis A, Stussi G, Broggini M, Wymann MP, Wicki A, Zucca E, Cmiljanovic V, Fabbro D, Bertoni F.

Clin Cancer Res. 2018 Jan 1;24(1):120-129. doi: 10.1158/1078-0432.CCR-17-1041. Epub 2017 Oct 24.

12.

MRI characteristics of the glia limitans externa: A 7T study.

Suzuki K, Yamada K, Nakada K, Suzuki Y, Watanabe M, Kwee IL, Nakada T.

Magn Reson Imaging. 2017 Dec;44:140-145. doi: 10.1016/j.mri.2017.08.012. Epub 2017 Sep 10.

13.

Aquaporin-4 Functionality and Virchow-Robin Space Water Dynamics: Physiological Model for Neurovascular Coupling and Glymphatic Flow.

Nakada T, Kwee IL, Igarashi H, Suzuki Y.

Int J Mol Sci. 2017 Aug 18;18(8). pii: E1798. doi: 10.3390/ijms18081798. Review.

14.

PCSF: An R-package for network-based interpretation of high-throughput data.

Akhmedov M, Kedaigle A, Chong RE, Montemanni R, Bertoni F, Fraenkel E, Kwee I.

PLoS Comput Biol. 2017 Jul 31;13(7):e1005694. doi: 10.1371/journal.pcbi.1005694. eCollection 2017 Jul.

15.

Diffuse large B cell lymphoma cell of origin by digital expression profiling in the REAL07 Phase 1-2 study.

Cascione L, Rinaldi A, Chiappella A, Kwee I, Ciccone G, Altenbuchinger M, Kohler C, Vitolo U, Inghirami G, Bertoni F.

Br J Haematol. 2017 Jul 24. doi: 10.1111/bjh.14817. [Epub ahead of print] No abstract available.

PMID:
28737236
16.

Preclinical evaluation of the BET bromodomain inhibitor BAY 1238097 for the treatment of lymphoma.

Bernasconi E, Gaudio E, Lejeune P, Tarantelli C, Cascione L, Kwee I, Spriano F, Rinaldi A, Mensah AA, Chung E, Stathis A, Siegel S, Schmees N, Ocker M, Zucca E, Haendler B, Bertoni F.

Br J Haematol. 2017 Sep;178(6):936-948. doi: 10.1111/bjh.14803. Epub 2017 Jun 27.

PMID:
28653353
17.

Aquaporin Positron Emission Tomography Differentiates Between Grade III and IV Human Astrocytoma.

Suzuki Y, Nakamura Y, Yamada K, Kurabe S, Okamoto K, Aoki H, Kitaura H, Kakita A, Fujii Y, Huber VJ, Igarashi H, Kwee IL, Nakada T.

Neurosurgery. 2018 Jun 1;82(6):842-846. doi: 10.1093/neuros/nyx314.

18.

The bromodomain inhibitor OTX015 (MK-8628) exerts anti-tumor activity in triple-negative breast cancer models as single agent and in combination with everolimus.

Vázquez R, Riveiro ME, Astorgues-Xerri L, Odore E, Rezai K, Erba E, Panini N, Rinaldi A, Kwee I, Beltrame L, Bekradda M, Cvitkovic E, Bertoni F, Frapolli R, D'Incalci M.

Oncotarget. 2017 Jan 31;8(5):7598-7613. doi: 10.18632/oncotarget.13814.

19.

OTX015 (MK-8628), a novel BET inhibitor, exhibits antitumor activity in non-small cell and small cell lung cancer models harboring different oncogenic mutations.

Riveiro ME, Astorgues-Xerri L, Vazquez R, Frapolli R, Kwee I, Rinaldi A, Odore E, Rezai K, Bekradda M, Inghirami G, D'Incalci M, Noel K, Cvitkovic E, Raymond E, Bertoni F.

Oncotarget. 2016 Dec 20;7(51):84675-84687. doi: 10.18632/oncotarget.13181.

20.

Therapeutic efficacy of the bromodomain inhibitor OTX015/MK-8628 in ALK-positive anaplastic large cell lymphoma: an alternative modality to overcome resistant phenotypes.

Boi M, Todaro M, Vurchio V, Yang SN, Moon J, Kwee I, Rinaldi A, Pan H, Crescenzo R, Cheng M, Cerchietti L, Elemento O, Riveiro ME, Cvitkovic E, Bertoni F, Inghirami G; AIRC 5xMille Consortium ‘Genetics-Driven Targeted Management of Lymphoid Malignancies’.

Oncotarget. 2016 Nov 29;7(48):79637-79653. doi: 10.18632/oncotarget.12876.

21.

Sleep Apnea in Multiple System Atrophy of Cerebellar Type: A 3.0 T MRS/Volumetry Pilot Study.

Takado Y, Terajima K, Shimohata T, Nakayama H, Watanabe M, Okamoto K, Ozawa T, Nishizawa M, Kwee IL, Igarashi H, Nakada T.

eNeurologicalSci. 2016 Oct 11;6:6-8. doi: 10.1016/j.ensci.2016.10.002. eCollection 2017 Mar. No abstract available.

22.

Assessment of the Antiproliferative Activity of a BET Bromodomain Inhibitor as Single Agent and in Combination in Non-Hodgkin Lymphoma Cell Lines.

Bernasconi E, Gaudio E, Kwee I, Bertoni F.

Methods Mol Biol. 2016;1436:305-12. doi: 10.1007/978-1-4939-3667-0_20.

PMID:
27246223
23.

Combination of the MEK inhibitor pimasertib with BTK or PI3K-delta inhibitors is active in preclinical models of aggressive lymphomas.

Gaudio E, Tarantelli C, Kwee I, Barassi C, Bernasconi E, Rinaldi A, Ponzoni M, Cascione L, Targa A, Stathis A, Goodstal S, Zucca E, Bertoni F.

Ann Oncol. 2016 Jun;27(6):1123-8. doi: 10.1093/annonc/mdw131. Epub 2016 Mar 8.

PMID:
26961147
24.

Identification of a new subclass of ALK-negative ALCL expressing aberrant levels of ERBB4 transcripts.

Scarfò I, Pellegrino E, Mereu E, Kwee I, Agnelli L, Bergaggio E, Garaffo G, Vitale N, Caputo M, Machiorlatti R, Circosta P, Abate F, Barreca A, Novero D, Mathew S, Rinaldi A, Tiacci E, Serra S, Deaglio S, Neri A, Falini B, Rabadan R, Bertoni F, Inghirami G, Piva R; European T-Cell Lymphoma Study Group.

Blood. 2016 Jan 14;127(2):221-32. doi: 10.1182/blood-2014-12-614503. Epub 2015 Oct 13.

25.

Characterization of a mantle cell lymphoma cell line resistant to the Chk1 inhibitor PF-00477736.

Restelli V, Chilà R, Lupi M, Rinaldi A, Kwee I, Bertoni F, Damia G, Carrassa L.

Oncotarget. 2015 Nov 10;6(35):37229-40. doi: 10.18632/oncotarget.5954.

26.

The novel atypical retinoid ST5589 down-regulates Aurora Kinase A and has anti-tumour activity in lymphoma pre-clinical models.

Bernasconi E, Gaudio E, Kwee I, Rinaldi A, Cascione L, Tarantelli C, Mensah AA, Stathis A, Zucca E, Vesci L, Giannini G, Bertoni F.

Br J Haematol. 2015 Nov;171(3):378-86. doi: 10.1111/bjh.13595. Epub 2015 Aug 3.

PMID:
26235926
27.

Reduced CSF Water Influx in Alzheimer's Disease Supporting the β-Amyloid Clearance Hypothesis.

Suzuki Y, Nakamura Y, Yamada K, Igarashi H, Kasuga K, Yokoyama Y, Ikeuchi T, Nishizawa M, Kwee IL, Nakada T.

PLoS One. 2015 May 6;10(5):e0123708. doi: 10.1371/journal.pone.0123708. eCollection 2015.

28.

Covert effects of "one drink" of alcohol on brain processes related to car driving: an event-related potential study.

Ebe K, Itoh K, Kwee IL, Nakada T.

Neurosci Lett. 2015 Apr 23;593:78-82. doi: 10.1016/j.neulet.2015.03.020. Epub 2015 Mar 18.

PMID:
25796178
29.

Preclinical antitumor activity of ST7612AA1: a new oral thiol-based histone deacetylase (HDAC) inhibitor.

Vesci L, Bernasconi E, Milazzo FM, De Santis R, Gaudio E, Kwee I, Rinaldi A, Pace S, Carollo V, Giannini G, Bertoni F.

Oncotarget. 2015 Mar 20;6(8):5735-48.

30.

Novel HDAC inhibitors exhibit pre-clinical efficacy in lymphoma models and point to the importance of CDKN1A expression levels in mediating their anti-tumor response.

Mensah AA, Kwee I, Gaudio E, Rinaldi A, Ponzoni M, Cascione L, Fossati G, Stathis A, Zucca E, Caprini G, Bertoni F.

Oncotarget. 2015 Mar 10;6(7):5059-71.

31.

The BET Bromodomain Inhibitor OTX015 Affects Pathogenetic Pathways in Preclinical B-cell Tumor Models and Synergizes with Targeted Drugs.

Boi M, Gaudio E, Bonetti P, Kwee I, Bernasconi E, Tarantelli C, Rinaldi A, Testoni M, Cascione L, Ponzoni M, Mensah AA, Stathis A, Stussi G, Riveiro ME, Herait P, Inghirami G, Cvitkovic E, Zucca E, Bertoni F.

Clin Cancer Res. 2015 Apr 1;21(7):1628-38. doi: 10.1158/1078-0432.CCR-14-1561. Epub 2015 Jan 26.

32.

DNA methylation profiling identifies two splenic marginal zone lymphoma subgroups with different clinical and genetic features.

Arribas AJ, Rinaldi A, Mensah AA, Kwee I, Cascione L, Robles EF, Martinez-Climent JA, Oscier D, Arcaini L, Baldini L, Marasca R, Thieblemont C, Briere J, Forconi F, Zamò A, Bonifacio M, Mollejo M, Facchetti F, Dirnhofer S, Ponzoni M, Bhagat G, Piris MA, Gaidano G, Zucca E, Rossi D, Bertoni F.

Blood. 2015 Mar 19;125(12):1922-31. doi: 10.1182/blood-2014-08-596247. Epub 2015 Jan 22.

33.

High fidelity between saliva proteomics and the biologic state of salivary glands defines biomarker signatures for primary Sjögren's syndrome.

Delaleu N, Mydel P, Kwee I, Brun JG, Jonsson MV, Jonsson R.

Arthritis Rheumatol. 2015 Apr;67(4):1084-95. doi: 10.1002/art.39015.

34.

A novel patient-derived tumorgraft model with TRAF1-ALK anaplastic large-cell lymphoma translocation.

Abate F, Todaro M, van der Krogt JA, Boi M, Landra I, Machiorlatti R, Tabbò F, Messana K, Abele C, Barreca A, Novero D, Gaudiano M, Aliberti S, Di Giacomo F, Tousseyn T, Lasorsa E, Crescenzo R, Bessone L, Ficarra E, Acquaviva A, Rinaldi A, Ponzoni M, Longo DL, Aime S, Cheng M, Ruggeri B, Piccaluga PP, Pileri S, Tiacci E, Falini B, Pera-Gresely B, Cerchietti L, Iqbal J, Chan WC, Shultz LD, Kwee I, Piva R, Wlodarska I, Rabadan R, Bertoni F, Inghirami G; European T-cell Lymphoma Study Group.

Leukemia. 2015 Jun;29(6):1390-401. doi: 10.1038/leu.2014.347. Epub 2014 Dec 23.

35.

Ligand-based molecular MRI: O-17 JJVCPE amyloid imaging in transgenic mice.

Suzuki K, Igarashi H, Huber VJ, Kitaura H, Kwee IL, Nakada T.

J Neuroimaging. 2014 Nov-Dec;24(6):595-598. doi: 10.1111/jon.12091. Epub 2014 Feb 23.

36.

Water influx into cerebrospinal fluid is significantly reduced in senile plaque bearing transgenic mice, supporting beta-amyloid clearance hypothesis of Alzheimer's disease.

Igarashi H, Suzuki Y, Kwee IL, Nakada T.

Neurol Res. 2014 Dec;36(12):1094-8. doi: 10.1179/1743132814Y.0000000434. Epub 2014 Aug 1.

37.

Distinct patterns of global promoter methylation in early stage chronic lymphocytic leukemia.

Ronchetti D, Tuana G, Rinaldi A, Agnelli L, Cutrona G, Mosca L, Fabris S, Matis S, Colombo M, Gentile M, Recchia AG, Kwee I, Bertoni F, Morabito F, Ferrarini M, Neri A.

Genes Chromosomes Cancer. 2014 Mar;53(3):264-73. doi: 10.1002/gcc.22139. Epub 2013 Dec 18.

PMID:
24347044
38.

Genome-wide DNA profiling identifies clonal heterogeneity in marginal zone lymphomas.

Mian M, Kwee I, Rinaldi A, Ponzoni M, Bhagat G, Rossi D, Arcaini L, Gascoyne RD, Mollejo M, Baldini L, Thieblemont C, Gaidano G, Zucca E, Bertoni F.

Br J Haematol. 2014 Mar;164(6):896-9. doi: 10.1111/bjh.12688. Epub 2013 Dec 11. No abstract available.

PMID:
24329863
39.

Whole-exome sequencing in splenic marginal zone lymphoma reveals mutations in genes involved in marginal zone differentiation.

Martínez N, Almaraz C, Vaqué JP, Varela I, Derdak S, Beltran S, Mollejo M, Campos-Martin Y, Agueda L, Rinaldi A, Kwee I, Gut M, Blanc J, Oscier D, Strefford JC, Martinez-Lopez J, Salar A, Sole F, Rodriguez-Peralto JL, Diez-Tascón C, García JF, Fraga M, Sebastián E, Alvés J, Menárguez J, González-Carreró J, Casado LF, Bayes M, Bertoni F, Gut I, Piris MA.

Leukemia. 2014 Jun;28(6):1334-40. doi: 10.1038/leu.2013.365. Epub 2013 Dec 3.

PMID:
24296945
40.

Discovering subgroups of patients from DNA copy number data using NMF on compacted matrices.

de Campos CP, Rancoita PM, Kwee I, Zucca E, Zaffalon M, Bertoni F.

PLoS One. 2013 Nov 20;8(11):e79720. doi: 10.1371/journal.pone.0079720. eCollection 2013.

41.

Water influx into cerebrospinal fluid is primarily controlled by aquaporin-4, not by aquaporin-1: 17O JJVCPE MRI study in knockout mice.

Igarashi H, Tsujita M, Kwee IL, Nakada T.

Neuroreport. 2014 Jan 8;25(1):39-43. doi: 10.1097/WNR.0000000000000042.

42.

PRDM1/BLIMP1 is commonly inactivated in anaplastic large T-cell lymphoma.

Boi M, Rinaldi A, Kwee I, Bonetti P, Todaro M, Tabbò F, Piva R, Rancoita PM, Matolcsy A, Timar B, Tousseyn T, Rodríguez-Pinilla SM, Piris MA, Beà S, Campo E, Bhagat G, Swerdlow SH, Rosenwald A, Ponzoni M, Young KH, Piccaluga PP, Dummer R, Pileri S, Zucca E, Inghirami G, Bertoni F.

Blood. 2013 Oct 10;122(15):2683-93. doi: 10.1182/blood-2013-04-497933. Epub 2013 Sep 4.

43.

Two main genetic pathways lead to the transformation of chronic lymphocytic leukemia to Richter syndrome.

Chigrinova E, Rinaldi A, Kwee I, Rossi D, Rancoita PM, Strefford JC, Oscier D, Stamatopoulos K, Papadaki T, Berger F, Young KH, Murray F, Rosenquist R, Greiner TC, Chan WC, Orlandi EM, Lucioni M, Marasca R, Inghirami G, Ladetto M, Forconi F, Cogliatti S, Votavova H, Swerdlow SH, Stilgenbauer S, Piris MA, Matolcsy A, Spagnolo D, Nikitin E, Zamò A, Gattei V, Bhagat G, Ott G, Zucca E, Gaidano G, Bertoni F.

Blood. 2013 Oct 10;122(15):2673-82. doi: 10.1182/blood-2013-03-489518. Epub 2013 Sep 4.

44.

Promoter methylation patterns in Richter syndrome affect stem-cell maintenance and cell cycle regulation and differ from de novo diffuse large B-cell lymphoma.

Rinaldi A, Mensah AA, Kwee I, Forconi F, Orlandi EM, Lucioni M, Gattei V, Marasca R, Berger F, Cogliatti S, Cavalli F, Zucca E, Gaidano G, Rossi D, Bertoni F.

Br J Haematol. 2013 Oct;163(2):194-204. doi: 10.1111/bjh.12515. Epub 2013 Aug 21.

PMID:
23961875
45.

Deregulation of ETS1 and FLI1 contributes to the pathogenesis of diffuse large B-cell lymphoma.

Bonetti P, Testoni M, Scandurra M, Ponzoni M, Piva R, Mensah AA, Rinaldi A, Kwee I, Tibiletti MG, Iqbal J, Greiner TC, Chan WC, Gaidano G, Piris MA, Cavalli F, Zucca E, Inghirami G, Bertoni F.

Blood. 2013 Sep 26;122(13):2233-41. doi: 10.1182/blood-2013-01-475772. Epub 2013 Aug 7. Erratum in: Blood. 2014 May 8;123(19):3056.

46.

Genome-wide high resolution DNA profiling of hairy cell leukaemia.

Rinaldi A, Kwee I, Young KH, Zucca E, Gaidano G, Forconi F, Bertoni F.

Br J Haematol. 2013 Aug;162(4):566-9. doi: 10.1111/bjh.12393. Epub 2013 May 21. No abstract available.

PMID:
23692203
47.

Inhibition of aquaporin-4 significantly increases regional cerebral blood flow.

Igarashi H, Tsujita M, Suzuki Y, Kwee IL, Nakada T.

Neuroreport. 2013 Apr 17;24(6):324-8. doi: 10.1097/WNR.0b013e32835fc827.

PMID:
23462267
48.

Large genomic aberrations detected by SNP array are independent prognosticators of a shorter time to first treatment in chronic lymphocytic leukemia patients with normal FISH.

Mian M, Rinaldi A, Mensah AA, Rossi D, Ladetto M, Forconi F, Marasca R, Uhr M, Stussi G, Kwee I, Cavalli F, Gaidano G, Zucca E, Bertoni F.

Ann Oncol. 2013 May;24(5):1378-84. doi: 10.1093/annonc/mds646. Epub 2013 Jan 31.

PMID:
23372049
49.

Effects of musical training on the early auditory cortical representation of pitch transitions as indexed by change-N1.

Itoh K, Okumiya-Kanke Y, Nakayama Y, Kwee IL, Nakada T.

Eur J Neurosci. 2012 Dec;36(11):3580-92. doi: 10.1111/j.1460-9568.2012.08278.x. Epub 2012 Sep 7.

PMID:
22958242
50.

Neural strategies for reading Japanese and Chinese sentences: a cross-linguistic fMRI study of character-decoding and morphosyntax.

Huang K, Itoh K, Kwee IL, Nakada T.

Neuropsychologia. 2012 Sep;50(11):2598-604. doi: 10.1016/j.neuropsychologia.2012.07.011. Epub 2012 Jul 20.

PMID:
22820634

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