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Items: 1 to 50 of 61

1.

Diagnostic Workup and Evaluation of Patients with Prurigo Nodularis.

Kwon CD, Khanna R, Williams KA, Kwatra MM, Kwatra SG.

Medicines (Basel). 2019 Sep 26;6(4). pii: E97. doi: 10.3390/medicines6040097.

2.

Effects of neuroimmune axis modulation by aprepitant on antipruritic and global disease severity in patients with cutaneous T-cell lymphoma.

Kwatra SG, Boozalis E, Kwatra MM.

Br J Dermatol. 2018 May;178(5):1221-1222. doi: 10.1111/bjd.16363. Epub 2018 Mar 2. No abstract available.

PMID:
29352478
3.

Aprepitant for the Treatment of Chronic Refractory Pruritus.

He A, Alhariri JM, Sweren RJ, Kwatra MM, Kwatra SG.

Biomed Res Int. 2017;2017:4790810. doi: 10.1155/2017/4790810. Epub 2017 Sep 19. Review.

4.

A Rational Approach to Target the Epidermal Growth Factor Receptor in Glioblastoma.

Kwatra MM.

Curr Cancer Drug Targets. 2017;17(3):290-296. doi: 10.2174/1568009616666161227091522. Review.

5.

Association between Serum IGF-I levels and Postoperative Delirium in Elderly Subjects Undergoing Elective Knee Arthroplasty.

Yen TE, Allen JC, Rivelli SK, Patterson SC, Metcalf MR, Flink BJ, Mirrakhimov AE, Lagoo SA, Vail TP, Young CC, Moon RE, Trzepacz PT, Kwatra MM.

Sci Rep. 2016 Feb 5;6:20736. doi: 10.1038/srep20736.

6.

Proteomic profiling of patient-derived glioblastoma xenografts identifies a subset with activated EGFR: implications for drug development.

Brown KE, Chagoya G, Kwatra SG, Yen T, Keir ST, Cooter M, Hoadley KA, Rasheed A, Lipp ES, Mclendon R, Ali-Osman F, Bigner DD, Sampson JH, Kwatra MM.

J Neurochem. 2015 Jun;133(5):730-8. doi: 10.1111/jnc.13032. Epub 2015 Feb 12.

7.

Propofol and the risk of delirium: exploring the anticholinergic properties of propofol.

Brown KE, Mirrakhimov AE, Yeddula K, Kwatra MM.

Med Hypotheses. 2013 Oct;81(4):536-9. doi: 10.1016/j.mehy.2013.06.027. Epub 2013 Jul 26.

PMID:
23891036
8.

Revisiting the prehypertension debate: increasing evidence for treatment yet randomized clinical trials are lacking.

Reed C, Kwatra SG, Brown K, Kwatra MM.

Blood Press. 2013 Dec;22(6):340-3. doi: 10.3109/08037051.2013.787705. Epub 2013 May 2.

PMID:
23638979
9.

Delirium after cardiac surgery: have we overlooked obstructive sleep apnea?

Mirrakhimov AE, Yen T, Kwatra MM.

Med Hypotheses. 2013 Jul;81(1):15-20. doi: 10.1016/j.mehy.2013.03.033. Epub 2013 Apr 22.

10.

Obstructive sleep apnea and delirium: exploring possible mechanisms.

Mirrakhimov AE, Brewbaker CL, Krystal AD, Kwatra MM.

Sleep Breath. 2014 Mar;18(1):19-29. doi: 10.1007/s11325-013-0846-z. Epub 2013 Apr 14. Review.

PMID:
23584846
11.

Prehypertension: to treat or not to treat should no longer be the question.

Kwatra SG, Kiely AE, Kwatra MM.

Hypertension. 2012 Apr;59(4):e27; author reply e28. doi: 10.1161/HYPERTENSIONAHA.111.190678. Epub 2012 Feb 27. No abstract available.

PMID:
22371356
12.

Obstructive sleep apnea and incidence of postoperative delirium after elective knee replacement in the nondemented elderly.

Flink BJ, Rivelli SK, Cox EA, White WD, Falcone G, Vail TP, Young CC, Bolognesi MP, Krystal AD, Trzepacz PT, Moon RE, Kwatra MM.

Anesthesiology. 2012 Apr;116(4):788-96. doi: 10.1097/ALN.0b013e31824b94fc.

13.

Prevention of intraoperative awareness.

Kwatra MM.

N Engl J Med. 2011 Nov 24;365(21):2033; author reply 2034-5. doi: 10.1056/NEJMc1110999. No abstract available.

PMID:
22111726
14.

Low expression of alpha-adrenergic receptors in the aging human heart.

Kwatra SG, Goldsmith LE, White WD, Lin SS, Kwatra MM.

J Am Geriatr Soc. 2010 Jan;58(1):210-2. doi: 10.1111/j.1532-5415.2009.02659.x. No abstract available.

PMID:
20122076
15.

Treating prehypertension: medically sound and economically viable.

Kiely AE, Kwatra SG, Kwatra MM.

Blood Press. 2009;18(6):300-3. doi: 10.3109/08037050903444024.

PMID:
19958077
16.

Flaws in the serum anticholinergic activity assay: implications for the study of delirium.

Cox EA, Kwatra SG, Shetty S, Kwatra MM.

J Am Geriatr Soc. 2009 Sep;57(9):1707-8. doi: 10.1111/j.1532-5415.2009.02411.x. No abstract available.

PMID:
19895433
17.

A constitutively active form of neurokinin 1 receptor and neurokinin 1 receptor-mediated apoptosis in glioblastomas.

Akazawa T, Kwatra SG, Goldsmith LE, Richardson MD, Cox EA, Sampson JH, Kwatra MM.

J Neurochem. 2009 May;109(4):1079-86. doi: 10.1111/j.1471-4159.2009.06032.x. Epub 2009 Mar 11.

18.

Selective activation of human atrial Galpha12 and Galpha13 by Galphaq-coupled angiotensin and endothelin receptors.

Kilts JD, Lin SS, Lowe JE, Kwatra MM.

J Cardiovasc Pharmacol. 2007 Sep;50(3):299-303.

PMID:
17878759
19.

Delirium in older persons.

Kwatra MM.

N Engl J Med. 2006 Jun 8;354(23):2509-11; author reply 2509-11. No abstract available.

PMID:
16764059
20.

Prevention of atrial fibrillation following cardiac surgery.

Kwatra MM.

JAMA. 2006 May 17;295(19):2247-8; author reply 2248. No abstract available.

PMID:
16705100
21.

Signal transduction through substance P receptor in human glioblastoma cells: roles for Src and PKCdelta.

Yamaguchi K, Richardson MD, Bigner DD, Kwatra MM.

Cancer Chemother Pharmacol. 2005 Dec;56(6):585-93. Epub 2005 Jul 13.

PMID:
16012865
22.

G alpha(q)-coupled receptors in human atrium function through protein kinase C epsilon and delta.

Kilts JD, Grocott HP, Kwatra MM.

J Mol Cell Cardiol. 2005 Feb;38(2):267-76. Epub 2005 Jan 20.

PMID:
15698833
23.
24.

Age increases expression and receptor-mediated activation of G alpha i in human atria.

Kilts JD, Akazawa T, El-Moalem HE, Mathew JP, Newman MF, Kwatra MM.

J Cardiovasc Pharmacol. 2003 Nov;42(5):662-70.

PMID:
14576516
25.

Human substance P receptor lacking the C-terminal domain remains competent to desensitize and internalize.

Richardson MD, Balius AM, Yamaguchi K, Freilich ER, Barak LS, Kwatra MM.

J Neurochem. 2003 Feb;84(4):854-63.

26.

Cardiopulmonary bypass decreases G protein-coupled receptor kinase activity and expression in human peripheral blood mononuclear cells.

Hagen SA, Kondyra AL, Grocott HP, El-Moalem H, Bainbridge D, Mathew JP, Newman MF, Reves JG, Schwinn DA, Kwatra MM.

Anesthesiology. 2003 Feb;98(2):343-8.

PMID:
12552191
27.

Human substance P receptor undergoes agonist-dependent phosphorylation by G protein-coupled receptor kinase 5 in vitro.

Warabi K, Richardson MD, Barry WT, Yamaguchi K, Roush ED, Nishimura K, Kwatra MM.

FEBS Lett. 2002 Jun 19;521(1-3):140-4.

28.

Age increases cardiac Galpha(i2) expression, resulting in enhanced coupling to G protein-coupled receptors.

Kilts JD, Akazawa T, Richardson MD, Kwatra MM.

J Biol Chem. 2002 Aug 23;277(34):31257-62. Epub 2002 Jun 13.

29.

Beta(2)-adrenergic and several other G protein-coupled receptors in human atrial membranes activate both G(s) and G(i).

Kilts JD, Gerhardt MA, Richardson MD, Sreeram G, Mackensen GB, Grocott HP, White WD, Davis RD, Newman MF, Reves JG, Schwinn DA, Kwatra MM.

Circ Res. 2000 Oct 13;87(8):705-9.

PMID:
11029407
30.

Multiple potential regulatory elements in the 5' flanking region of the human alpha 1a-adrenergic receptor.

Lee K, Richardson CD, Razik MA, Kwatra MM, Schwinn DA.

DNA Seq. 1998 Mar;8(4):271-6.

PMID:
10520459
33.

Acute myocardial beta-adrenergic receptor dysfunction after cardiopulmonary bypass in patients with cardiac valve disease. Duke Heart Center Perioperative Desensitization Group.

Gerhardt MA, Booth JV, Chesnut LC, Funk BL, el-Moalem HE, Kwatra MM, Schwinn DA.

Circulation. 1998 Nov 10;98(19 Suppl):II275-81.

PMID:
9852914
34.

Acute depression of myocardial beta-adrenergic receptor signaling during cardiopulmonary bypass: impairment of the adenylyl cyclase moiety. Duke Heart Center Perioperative Desensitization Group.

Booth JV, Landolfo KP, Chesnut LC, Bennett-Guerrero E, Gerhardt MA, Atwell DM, El-Moalem HE, Smith MS, Funk BL, Kuhn CM, Kwatra MM, Schwinn DA.

Anesthesiology. 1998 Sep;89(3):602-11.

PMID:
9743395
36.

New developments in cardiovascular adrenergic receptor pharmacology: molecular mechanisms and clinical relevance.

Smiley RM, Kwatra MM, Schwinn DA.

J Cardiothorac Vasc Anesth. 1998 Feb;12(1):80-95. Review. No abstract available.

PMID:
9509364
37.

Human substance P receptor expressed in Sf9 cells couples with multiple endogenous G proteins.

Nishimura K, Frederick J, Kwatra MM.

J Recept Signal Transduct Res. 1998 Jan;18(1):51-65.

PMID:
9493567
38.

Characterization of GRK2-catalyzed phosphorylation of the human substance P receptor in Sf9 membranes.

Nishimura K, Warabi K, Roush ED, Frederick J, Schwinn DA, Kwatra MM.

Biochemistry. 1998 Feb 3;37(5):1192-8.

PMID:
9477943
39.

Transcriptional regulation of the human alpha1a-adrenergic receptor gene. Characterization Of the 5'-regulatory and promoter region.

Razik MA, Lee K, Price RR, Williams MR, Ongjoco RR, Dole MK, Rudner XL, Kwatra MM, Schwinn DA.

J Biol Chem. 1997 Nov 7;272(45):28237-46.

40.

Expression and regulation of alpha 1-adrenergic receptors in human tissues.

Schwinn DA, Kwatra MM.

Adv Pharmacol. 1998;42:390-4. No abstract available.

PMID:
9327922
41.

Human G(alpha q): cDNA and tissue distribution.

Chen B, Leverette RD, Schwinn DA, Kwatra MM.

Biochim Biophys Acta. 1996 Jun 11;1281(2):125-8.

42.

Immunoaffinity purification of epitope-tagged human beta 2-adrenergic receptor to homogeneity.

Kwatra MM, Schreurs J, Schwinn DA, Innis MA, Caron MG, Lefkowitz RJ.

Protein Expr Purif. 1995 Dec;6(6):717-21.

PMID:
8746622
43.

Cardiac muscarinic potassium channel activity is attenuated by inhibitors of G beta gamma.

Nair LA, Inglese J, Stoffel R, Koch WJ, Lefkowitz RJ, Kwatra MM, Grant AO.

Circ Res. 1995 May;76(5):832-8.

PMID:
7729000
44.

A highly conserved tyrosine residue in G protein-coupled receptors is required for agonist-mediated beta 2-adrenergic receptor sequestration.

Barak LS, Tiberi M, Freedman NJ, Kwatra MM, Lefkowitz RJ, Caron MG.

J Biol Chem. 1994 Jan 28;269(4):2790-5.

45.

The substance P receptor, which couples to Gq/11, is a substrate of beta-adrenergic receptor kinase 1 and 2.

Kwatra MM, Schwinn DA, Schreurs J, Blank JL, Kim CM, Benovic JL, Krause JE, Caron MG, Lefkowitz RJ.

J Biol Chem. 1993 May 5;268(13):9161-4.

46.

Beta-arrestin2, a novel member of the arrestin/beta-arrestin gene family.

Attramadal H, Arriza JL, Aoki C, Dawson TM, Codina J, Kwatra MM, Snyder SH, Caron MG, Lefkowitz RJ.

J Biol Chem. 1992 Sep 5;267(25):17882-90.

47.

Role of beta gamma subunits of G proteins in targeting the beta-adrenergic receptor kinase to membrane-bound receptors.

Pitcher JA, Inglese J, Higgins JB, Arriza JL, Casey PJ, Kim C, Benovic JL, Kwatra MM, Caron MG, Lefkowitz RJ.

Science. 1992 Aug 28;257(5074):1264-7.

PMID:
1325672
48.

The ligand binding domain of the epidermal growth factor receptor is not required for receptor dimerization.

Kwatra MM, Bigner DD, Cohn JA.

Biochim Biophys Acta. 1992 Mar 16;1134(2):178-81.

PMID:
1554751
49.

Anti-synthetic peptide antibody reacting at the fusion junction of deletion-mutant epidermal growth factor receptors in human glioblastoma.

Humphrey PA, Wong AJ, Vogelstein B, Zalutsky MR, Fuller GN, Archer GE, Friedman HS, Kwatra MM, Bigner SH, Bigner DD.

Proc Natl Acad Sci U S A. 1990 Jun;87(11):4207-11.

50.

Regulation of receptor function by protein phosphorylation.

Hosey MM, Kwatra MM, Ptasienski J, Richardson RM.

Ann N Y Acad Sci. 1990;588:155-63. Review. No abstract available.

PMID:
2192639

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