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Items: 27


Glioblastoma-derived extracellular vesicles modify the phenotype of monocytic cells.

de Vrij J, Maas SL, Kwappenberg KM, Schnoor R, Kleijn A, Dekker L, Luider TM, de Witte LD, Litjens M, van Strien ME, Hol EM, Kroonen J, Robe PA, Lamfers ML, Schilham MW, Broekman ML.

Int J Cancer. 2015 Oct 1;137(7):1630-42. doi: 10.1002/ijc.29521. Epub 2015 Apr 7.


Macrophages inhibit human osteosarcoma cell growth after activation with the bacterial cell wall derivative liposomal muramyl tripeptide in combination with interferon-γ.

Pahl JH, Kwappenberg KM, Varypataki EM, Santos SJ, Kuijjer ML, Mohamed S, Wijnen JT, van Tol MJ, Cleton-Jansen AM, Egeler RM, Jiskoot W, Lankester AC, Schilham MW.

J Exp Clin Cancer Res. 2014 Mar 10;33:27. doi: 10.1186/1756-9966-33-27.


Antibody-dependent cell lysis by NK cells is preserved after sarcoma-induced inhibition of NK cell cytotoxicity.

Pahl JH, Ruslan SE, Kwappenberg KM, van Ostaijen-Ten Dam MM, van Tol MJ, Lankester AC, Schilham MW.

Cancer Immunol Immunother. 2013 Jul;62(7):1235-47. doi: 10.1007/s00262-013-1406-x. Epub 2013 Apr 27.


Adenovirus type 35, but not type 5, stimulates NK cell activation via plasmacytoid dendritic cells and TLR9 signaling.

Pahl JH, Verhoeven DH, Kwappenberg KM, Vellinga J, Lankester AC, van Tol MJ, Schilham MW.

Mol Immunol. 2012 May;51(1):91-100. doi: 10.1016/j.molimm.2012.02.119. Epub 2012 Mar 16.


Enhanced transduction of CAR-negative cells by protein IX-gene deleted adenovirus 5 vectors.

de Vrij J, van den Hengel SK, Uil TG, Koppers-Lalic D, Dautzenberg IJ, Stassen OM, Bárcena M, Yamamoto M, de Ridder CM, Kraaij R, Kwappenberg KM, Schilham MW, Hoeben RC.

Virology. 2011 Feb 5;410(1):192-200. doi: 10.1016/j.virol.2010.10.040. Epub 2010 Dec 4.


Evaluation of immunological cross-reactivity between clade A9 high-risk human papillomavirus types on the basis of E6-Specific CD4+ memory T cell responses.

van den Hende M, Redeker A, Kwappenberg KM, Franken KL, Drijfhout JW, Oostendorp J, Valentijn AR, Fathers LM, Welters MJ, Melief CJ, Kenter GG, van der Burg SH, Offringa R.

J Infect Dis. 2010 Oct 15;202(8):1200-11. doi: 10.1086/656367.


Influenza matrix 1-specific human CD4+ FOXP3+ and FOXP3(-) regulatory T cells can be detected long after viral clearance.

Piersma SJ, van der Hulst JM, Kwappenberg KM, Goedemans R, van der Minne CE, van der Burg SH.

Eur J Immunol. 2010 Nov;40(11):3064-74. doi: 10.1002/eji.200940177. Epub 2010 Sep 6.


A prospective study on the natural course of low-grade squamous intraepithelial lesions and the presence of HPV16 E2-, E6- and E7-specific T-cell responses.

Woo YL, van den Hende M, Sterling JC, Coleman N, Crawford RA, Kwappenberg KM, Stanley MA, van der Burg SH.

Int J Cancer. 2010 Jan 1;126(1):133-41. doi: 10.1002/ijc.24804.


Human papilloma virus specific T cells infiltrating cervical cancer and draining lymph nodes show remarkably frequent use of HLA-DQ and -DP as a restriction element.

Piersma SJ, Welters MJ, van der Hulst JM, Kloth JN, Kwappenberg KM, Trimbos BJ, Melief CJ, Hellebrekers BW, Fleuren GJ, Kenter GG, Offringa R, van der Burg SH.

Int J Cancer. 2008 Feb 1;122(3):486-94.


Association of cervical cancer with the presence of CD4+ regulatory T cells specific for human papillomavirus antigens.

van der Burg SH, Piersma SJ, de Jong A, van der Hulst JM, Kwappenberg KM, van den Hende M, Welters MJ, Van Rood JJ, Fleuren GJ, Melief CJ, Kenter GG, Offringa R.

Proc Natl Acad Sci U S A. 2007 Jul 17;104(29):12087-92. Epub 2007 Jul 5.


Genetic variation of antigen processing machinery components and association with cervical carcinoma.

Mehta AM, Jordanova ES, van Wezel T, Uh HW, Corver WE, Kwappenberg KM, Verduijn W, Kenter GG, van der Burg SH, Fleuren GJ.

Genes Chromosomes Cancer. 2007 Jun;46(6):577-86.


High number of intraepithelial CD8+ tumor-infiltrating lymphocytes is associated with the absence of lymph node metastases in patients with large early-stage cervical cancer.

Piersma SJ, Jordanova ES, van Poelgeest MI, Kwappenberg KM, van der Hulst JM, Drijfhout JW, Melief CJ, Kenter GG, Fleuren GJ, Offringa R, van der Burg SH.

Cancer Res. 2007 Jan 1;67(1):354-61.


Detection of human papillomavirus type 18 E6 and E7-specific CD4+ T-helper 1 immunity in relation to health versus disease.

Welters MJ, van der Logt P, van den Eeden SJ, Kwappenberg KM, Drijfhout JW, Fleuren GJ, Kenter GG, Melief CJ, van der Burg SH, Offringa R.

Int J Cancer. 2006 Feb 15;118(4):950-6.


Distinct regulation and impact of type 1 T-cell immunity against HPV16 L1, E2 and E6 antigens during HPV16-induced cervical infection and neoplasia.

van Poelgeest MI, Nijhuis ER, Kwappenberg KM, Hamming IE, Wouter Drijfhout J, Fleuren GJ, van der Zee AG, Melief CJ, Kenter GG, Nijman HW, Offringa R, van der Burg SH.

Int J Cancer. 2006 Feb 1;118(3):675-83.


Detection of human papillomavirus (HPV) 16-specific CD4+ T-cell immunity in patients with persistent HPV16-induced vulvar intraepithelial neoplasia in relation to clinical impact of imiquimod treatment.

van Poelgeest MI, van Seters M, van Beurden M, Kwappenberg KM, Heijmans-Antonissen C, Drijfhout JW, Melief CJ, Kenter GG, Helmerhorst TJ, Offringa R, van der Burg SH.

Clin Cancer Res. 2005 Jul 15;11(14):5273-80.


Immunological responses in women with human papillomavirus type 16 (HPV-16)-associated anogenital intraepithelial neoplasia induced by heterologous prime-boost HPV-16 oncogene vaccination.

Smyth LJ, Van Poelgeest MI, Davidson EJ, Kwappenberg KM, Burt D, Sehr P, Pawlita M, Man S, Hickling JK, Fiander AN, Tristram A, Kitchener HC, Offringa R, Stern PL, Van Der Burg SH.

Clin Cancer Res. 2004 May 1;10(9):2954-61.


Frequent display of human papillomavirus type 16 E6-specific memory t-Helper cells in the healthy population as witness of previous viral encounter.

Welters MJ, de Jong A, van den Eeden SJ, van der Hulst JM, Kwappenberg KM, Hassane S, Franken KL, Drijfhout JW, Fleuren GJ, Kenter G, Melief CJ, Offringa R, van der Burg SH.

Cancer Res. 2003 Feb 1;63(3):636-41.


Enhancement of human papillomavirus (HPV) type 16 E6 and E7-specific T-cell immunity in healthy volunteers through vaccination with TA-CIN, an HPV16 L2E7E6 fusion protein vaccine.

de Jong A, O'Neill T, Khan AY, Kwappenberg KM, Chisholm SE, Whittle NR, Dobson JA, Jack LC, St Clair Roberts JA, Offringa R, van der Burg SH, Hickling JK.

Vaccine. 2002 Oct 4;20(29-30):3456-64.


Frequent detection of human papillomavirus 16 E2-specific T-helper immunity in healthy subjects.

de Jong A, van der Burg SH, Kwappenberg KM, van der Hulst JM, Franken KL, Geluk A, van Meijgaarden KE, Drijfhout JW, Kenter G, Vermeij P, Melief CJ, Offringa R.

Cancer Res. 2002 Jan 15;62(2):472-9.


Pre-clinical safety and efficacy of TA-CIN, a recombinant HPV16 L2E6E7 fusion protein vaccine, in homologous and heterologous prime-boost regimens.

van der Burg SH, Kwappenberg KM, O'Neill T, Brandt RM, Melief CJ, Hickling JK, Offringa R.

Vaccine. 2001 Jun 14;19(27):3652-60.


Natural T-helper immunity against human papillomavirus type 16 (HPV16) E7-derived peptide epitopes in patients with HPV16-positive cervical lesions: identification of 3 human leukocyte antigen class II-restricted epitopes.

van der Burg SH, Ressing ME, Kwappenberg KM, de Jong A, Straathof K, de Jong J, Geluk A, van Meijgaarden KE, Franken KL, Ottenhoff TH, Fleuren GJ, Kenter G, Melief CJ, Offringa R.

Int J Cancer. 2001 Mar 1;91(5):612-8.


Molecular mimicry of human cytochrome P450 by hepatitis C virus at the level of cytotoxic T cell recognition.

Kammer AR, van der Burg SH, Grabscheid B, Hunziker IP, Kwappenberg KM, Reichen J, Melief CJ, Cerny A.

J Exp Med. 1999 Jul 19;190(2):169-76.


Identification of a conserved universal Th epitope in HIV-1 reverse transcriptase that is processed and presented to HIV-specific CD4+ T cells by at least four unrelated HLA-DR molecules.

van der Burg SH, Kwappenberg KM, Geluk A, van der Kruk M, Pontesilli O, Hovenkamp E, Franken KL, van Meijgaarden KE, Drijfhout JW, Ottenhoff TH, Melief CJ, Offringa R.

J Immunol. 1999 Jan 1;162(1):152-60.


Antibiotic-induced lipopolysaccharide (LPS) release from Salmonella typhi: delay between killing by ceftazidime and imipenem and release of LPS.

van Langevelde P, Kwappenberg KM, Groeneveld PH, Mattie H, van Dissel JT.

Antimicrob Agents Chemother. 1998 Apr;42(4):739-43.


Relation between pro- and anti-inflammatory cytokines and the production of nitric oxide (NO) in severe sepsis.

Groeneveld PH, Kwappenberg KM, Langermans JA, Nibbering PH, Curtis L.

Cytokine. 1997 Feb;9(2):138-42.


Nitric oxide (NO) production correlates with renal insufficiency and multiple organ dysfunction syndrome in severe sepsis.

Groeneveld PH, Kwappenberg KM, Langermans JA, Nibbering PH, Curtis L.

Intensive Care Med. 1996 Nov;22(11):1197-202.


Increased production of nitric oxide in patients infected with the European variant of hantavirus.

Groeneveld PH, Colson P, Kwappenberg KM, Clement J.

Scand J Infect Dis. 1995;27(5):453-6.


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