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Items: 1 to 50 of 233

1.

The effects of manipulating levels of replication initiation factors on origin firing efficiency in yeast.

Lynch KL, Alvino GM, Kwan EX, Brewer BJ, Raghuraman MK.

PLoS Genet. 2019 Oct 4;15(10):e1008430. doi: 10.1371/journal.pgen.1008430. [Epub ahead of print]

2.

Neurocognition in Adult Congenital Heart Disease: How to Monitor and Prevent Progressive Decline.

Keir M, Ebert P, Kovacs AH, Smith JMC, Kwan E, Field TS, Brossard-Racine M, Marelli A.

Can J Cardiol. 2019 Jun 26. pii: S0828-282X(19)30441-6. doi: 10.1016/j.cjca.2019.06.020. [Epub ahead of print] Review.

PMID:
31570238
3.

Matching Glycosyl Donor Reactivity to Sulfonate Leaving Group Ability Permits SN2 Glycosylations.

Zhuo MH, Wilbur DJ, Kwan EE, Bennett CS.

J Am Chem Soc. 2019 Oct 9. doi: 10.1021/jacs.9b07022. [Epub ahead of print]

PMID:
31550879
4.

Phenotypic and Genotypic Consequences of CRISPR/Cas9 Editing of the Replication Origins in the rDNA of Saccharomyces cerevisiae.

Sanchez JC, Ollodart A, Large CRL, Clough C, Alvino GM, Tsuchiya M, Crane M, Kwan EX, Kaeberlein M, Dunham MJ, Raghuraman MK, Brewer BJ.

Genetics. 2019 Sep;213(1):229-249. doi: 10.1534/genetics.119.302351. Epub 2019 Jul 10.

5.

Prevalence, detection and associations of depression in Australian dialysis patients.

Kwan E, Draper B, Harvey SB, Endre ZH, Brown MA.

Australas Psychiatry. 2019 Oct;27(5):444-449. doi: 10.1177/1039856219859281. Epub 2019 Jul 9.

PMID:
31287327
6.

Passenger hotspot mutations in cancer driven by APOBEC3A and mesoscale genomic features.

Buisson R, Langenbucher A, Bowen D, Kwan EE, Benes CH, Zou L, Lawrence MS.

Science. 2019 Jun 28;364(6447). pii: eaaw2872. doi: 10.1126/science.aaw2872.

7.

Changes in atrial electrophysiological and structural substrate and their relationship to histology in a long-term chronic canine atrial fibrillation model.

Yamashita K, Silvernagel J, Kwan E, Kamali R, Ghafoori E, MacLeod R, Dosdall DJ, Ranjan R.

Pacing Clin Electrophysiol. 2019 Jul;42(7):930-936. doi: 10.1111/pace.13730. Epub 2019 Jun 4.

PMID:
31127633
8.

Prognostic Utility of a Whole-blood Androgen Receptor-based Gene Signature in Metastatic Castration-resistant Prostate Cancer.

Kwan EM, Fettke H, Docanto MM, To SQ, Bukczynska P, Mant A, Pook D, Ng N, Graham LK, Mangiola S, Segelov E, Mahon K, Davis ID, Parente P, Pezaro C, Todenhöfer T, Horvath LG, Azad AA.

Eur Urol Focus. 2019 May 15. pii: S2405-4569(19)30139-7. doi: 10.1016/j.euf.2019.04.020. [Epub ahead of print]

PMID:
31103601
9.

Draft Whole-Genome Sequences of Three Isolates of a Novel Strain of a Campylobacter sp. Isolated from New Zealand Birds and Water.

Wilkinson DA, Midwinter AC, Kwan E, Bloomfield SJ, French NP, Biggs PJ.

Microbiol Resour Announc. 2019 May 2;8(18). pii: e00258-19. doi: 10.1128/MRA.00258-19.

10.

Dextrose gels for neonatal transitional hypoglycemia: What are we giving our babies?

Solimano A, Kwan E, Osiovich H, Dyer R, Elango R.

Paediatr Child Health. 2019 May;24(2):115-118. doi: 10.1093/pch/pxy185. Epub 2019 Feb 5.

PMID:
30996602
11.

CRISPR-suppressor scanning reveals a nonenzymatic role of LSD1 in AML.

Vinyard ME, Su C, Siegenfeld AP, Waterbury AL, Freedy AM, Gosavi PM, Park Y, Kwan EE, Senzer BD, Doench JG, Bauer DE, Pinello L, Liau BB.

Nat Chem Biol. 2019 May;15(5):529-539. doi: 10.1038/s41589-019-0263-0. Epub 2019 Apr 15.

PMID:
30992567
12.

Extending the Lifetime of Organic Flow Batteries via Redox State Management.

Goulet MA, Tong L, Pollack DA, Tabor DP, Odom SA, Aspuru-Guzik A, Kwan EE, Gordon RG, Aziz MJ.

J Am Chem Soc. 2019 May 22;141(20):8014-8019. doi: 10.1021/jacs.8b13295. Epub 2019 Apr 26.

PMID:
30945536
13.

Impact of access to novel therapies on the initial management of castrate-resistant prostate cancer: an Australian multicentre study.

Kwan EM, Semira MC, Bergin ART, Muttiah C, Beck S, Anton A, Campbell D, Wong S, Rosenthal M, Gibbs P, Tran B.

Intern Med J. 2019 Feb 18. doi: 10.1111/imj.14262. [Epub ahead of print]

PMID:
30779277
14.

Timing of brain metastases development in metastatic renal cell cancer patients treated with targeted therapies and survival outcomes: An Australian multicenter study.

Ha FJ, Spain L, Dowling A, Kwan EM, Pezaro C, Day D, Chia PL, Tran B, Pook D, Weickhardt AJ.

Asia Pac J Clin Oncol. 2019 Oct;15(5):e97-e102. doi: 10.1111/ajco.13109. Epub 2019 Jan 30.

PMID:
30701671
15.

Phase 1 trial of olaparib and oral cyclophosphamide in BRCA breast cancer, recurrent BRCA ovarian cancer, non-BRCA triple-negative breast cancer, and non-BRCA ovarian cancer.

Lee CK, Scott C, Lindeman GJ, Hamilton A, Lieschke E, Gibbs E, Asher R, Badger H, Paterson R, Macnab L, Kwan EM, Francis PA, Boyle F, Friedlander M.

Br J Cancer. 2019 Feb;120(3):279-285. doi: 10.1038/s41416-018-0349-6. Epub 2019 Jan 17.

PMID:
30655615
16.

Characterization of edema after cryo and radiofrequency ablations based on serial magnetic resonance imaging.

Yamashita K, Kholmovski E, Ghafoori E, Kamali R, Kwan E, Lichter J, MacLeod R, Dosdall DJ, Ranjan R.

J Cardiovasc Electrophysiol. 2019 Feb;30(2):255-262. doi: 10.1111/jce.13785. Epub 2018 Nov 21.

PMID:
30375090
17.

Cell-free DNA in cancer: current insights.

Fettke H, Kwan EM, Azad AA.

Cell Oncol (Dordr). 2019 Feb;42(1):13-28. doi: 10.1007/s13402-018-0413-5. Epub 2018 Oct 26. Review.

PMID:
30367445
18.

Localizing the Shape Transition in Neutron-Deficient Selenium.

Henderson J, Wu CY, Ash J, Bender PC, Elman B, Gade A, Grinder M, Iwasaki H, Kwan E, Longfellow B, Mijatović T, Rhodes D, Spieker M, Weisshaar D.

Phys Rev Lett. 2018 Aug 24;121(8):082502. doi: 10.1103/PhysRevLett.121.082502.

PMID:
30192612
19.

Concerted nucleophilic aromatic substitutions.

Kwan EE, Zeng Y, Besser HA, Jacobsen EN.

Nat Chem. 2018 Sep;10(9):917-923. doi: 10.1038/s41557-018-0079-7. Epub 2018 Jul 16.

20.

A quick and simple benchtop vortex egg-disruption approach for the molecular diagnosis of Fasciola hepatica from ruminant faecal samples.

Calvani NED, Cheng T, Green C, Hughes P, Kwan E, Maher E, Bush RD, Šlapeta J.

Parasitol Res. 2018 Aug;117(8):2685-2688. doi: 10.1007/s00436-018-5926-3. Epub 2018 May 22.

PMID:
29785618
21.

Expression of Androgen Receptor Splice Variant 7 or 9 in Whole Blood Does Not Predict Response to Androgen-Axis-targeting Agents in Metastatic Castration-resistant Prostate Cancer.

To SQ, Kwan EM, Fettke HC, Mant A, Docanto MM, Martelotto L, Bukczynska P, Ng N, Graham LK, Parente P, Pezaro C, Mahon K, Horvath L, Todenhöfer T, Azad AA.

Eur Urol. 2018 Jun;73(6):818-821. doi: 10.1016/j.eururo.2018.01.007.

PMID:
29398263
22.

Pharmacokinetics and Disposition of Momelotinib Revealed a Disproportionate Human Metabolite-Resolution for Clinical Development.

Zheng J, Xin Y, Zhang J, Subramanian R, Murray BP, Whitney JA, Warr MR, Ling J, Moorehead L, Kwan E, Hemenway J, Smith BJ, Silverman JA.

Drug Metab Dispos. 2018 Mar;46(3):237-247. doi: 10.1124/dmd.117.078899. Epub 2018 Jan 8.

PMID:
29311136
23.

Pharmacokinetics and Safety of Momelotinib in Subjects With Hepatic or Renal Impairment.

Xin Y, Kawashima J, Weng W, Kwan E, Tarnowski T, Silverman JA.

J Clin Pharmacol. 2018 Apr;58(4):522-532. doi: 10.1002/jcph.1050. Epub 2017 Dec 28.

PMID:
29283448
24.

A report of three families with FBN1-related acromelic dysplasias and review of literature for genotype-phenotype correlation in geleophysic dysplasia.

Cheng SW, Luk HM, Chu YWY, Tung YL, Kwan EY, Lo IF, Chung BH.

Eur J Med Genet. 2018 Apr;61(4):219-224. doi: 10.1016/j.ejmg.2017.11.018. Epub 2017 Nov 27. Review.

PMID:
29191498
25.

Precision oncology using a clinician-directed, tailored approach to molecular profiling.

Lam M, Tran B, Beck S, Tie J, Herath D, Whittle J, Kwan EM, Fox SB, Fellowes A, Ananda S, Lipton L, Gibbs P, Rosenthal MA, Desai J.

Asia Pac J Clin Oncol. 2018 Feb;14(1):84-90. doi: 10.1111/ajco.12787. Epub 2017 Oct 30.

PMID:
29083093
26.

Defective replication initiation results in locus specific chromosome breakage and a ribosomal RNA deficiency in yeast.

Sanchez JC, Kwan EX, Pohl TJ, Amemiya HM, Raghuraman MK, Brewer BJ.

PLoS Genet. 2017 Oct 16;13(10):e1007041. doi: 10.1371/journal.pgen.1007041. eCollection 2017 Oct.

27.

Impact of Granulocyte-colony Stimulating Factor on Bleomycin-induced Pneumonitis in Chemotherapy-treated Germ Cell Tumors.

Kwan EM, Beck S, Amir E, Jewett MA, Sturgeon JF, Anson-Cartwright L, Chung PW, Warde PR, Moore MJ, Bedard PL, Tran B.

Clin Genitourin Cancer. 2017 Sep 4. pii: S1558-7673(17)30267-7. doi: 10.1016/j.clgc.2017.08.012. [Epub ahead of print]

PMID:
28943331
28.

Observation of the Isovector Giant Monopole Resonance via the ^{28}Si(^{10}Be,^{10}B^{*}[1.74  MeV]) Reaction at 100  AMeV.

Scott M, Zegers RGT, Almus R, Austin SM, Bazin D, Brown BA, Campbell C, Gade A, Bowry M, Galès S, Garg U, Harakeh MN, Kwan E, Langer C, Loelius C, Lipschutz S, Litvinova E, Lunderberg E, Morse C, Noji S, Perdikakis G, Redpath T, Robin C, Sakai H, Sasamoto Y, Sasano M, Sullivan C, Tostevin JA, Uesaka T, Weisshaar D.

Phys Rev Lett. 2017 Apr 28;118(17):172501. doi: 10.1103/PhysRevLett.118.172501. Epub 2017 Apr 28.

29.

Respiratory syncytial virus-neutralizing serum antibody titers in infants following palivizumab prophylaxis with an abbreviated dosing regimen.

Claydon J, Sur A, Callejas A, Ladd M, Kwan E, Taylor R, Turvey SE, Solimano A, Lavoie PM, Marr N.

PLoS One. 2017 Apr 24;12(4):e0176152. doi: 10.1371/journal.pone.0176152. eCollection 2017.

30.

Macrocyclic bis-thioureas catalyze stereospecific glycosylation reactions.

Park Y, Harper KC, Kuhl N, Kwan EE, Liu RY, Jacobsen EN.

Science. 2017 Jan 13;355(6321):162-166. doi: 10.1126/science.aal1875.

31.

Sensitive and Accurate 13C Kinetic Isotope Effect Measurements Enabled by Polarization Transfer.

Kwan EE, Park Y, Besser HA, Anderson TL, Jacobsen EN.

J Am Chem Soc. 2017 Jan 11;139(1):43-46. doi: 10.1021/jacs.6b10621. Epub 2016 Dec 29.

32.

Benefit from cytoreductive nephrectomy and the prognostic role of neutrophil-to-lymphocyte ratio in patients with metastatic renal cell carcinoma.

Day D, Kanjanapan Y, Kwan E, Yip D, Lawrentschuk N, Davis ID, Azad AA, Wong S, Rosenthal M, Gibbs P, Tran B.

Intern Med J. 2016 Nov;46(11):1291-1297. doi: 10.1111/imj.13202.

PMID:
27507629
33.

Evaluation of the Significance of Starch Surface Binding Sites on Human Pancreatic α-Amylase.

Zhang X, Caner S, Kwan E, Li C, Brayer GD, Withers SG.

Biochemistry. 2016 Nov 1;55(43):6000-6009. Epub 2016 Oct 24.

PMID:
27756128
34.

Mechanistic Studies and Radiofluorination of Structurally Diverse Pharmaceuticals with Spirocyclic Iodonium(III) Ylides.

Rotstein BH, Wang L, Liu RY, Patteson J, Kwan EE, Vasdev N, Liang SH.

Chem Sci. 2016 Jul 1;7(7):4407-4417. Epub 2016 Mar 24.

35.

rDNA Copy Number Variants Are Frequent Passenger Mutations in Saccharomyces cerevisiae Deletion Collections and de Novo Transformants.

Kwan EX, Wang XS, Amemiya HM, Brewer BJ, Raghuraman MK.

G3 (Bethesda). 2016 Sep 8;6(9):2829-38. doi: 10.1534/g3.116.030296.

36.

A long-tethered (P-B-P)-pincer ligand: synthesis, complexation, and application to catalytic dehydrogenation of alkanes.

Kwan EH, Kawai YJ, Kamakura S, Yamashita M.

Dalton Trans. 2016 Oct 12;45(40):15931-15941.

PMID:
27383267
37.

Low plasma magnesium is associated with impaired brain metabolism in neonates with hypoxic-ischaemic encephalopathy.

Chakkarapani E, Chau V, Poskitt KJ, Synnes A, Kwan E, Roland E, Miller SP.

Acta Paediatr. 2016 Sep;105(9):1067-73. doi: 10.1111/apa.13505. Epub 2016 Jul 18.

PMID:
27336238
38.

Alloplastic Augmentation of the Asian Face: A Review of 215 Patients.

Chao JW, Lee JC, Chang MM, Kwan E.

Aesthet Surg J. 2016 Sep;36(8):861-8. doi: 10.1093/asj/sjw013. Epub 2016 Mar 1.

PMID:
26931309
39.

High Precision Determination of the β Decay Q(EC) Value of (11)C and Implications on the Tests of the Standard Model.

Gulyuz K, Bollen G, Brodeur M, Bryce RA, Cooper K, Eibach M, Izzo C, Kwan E, Manukyan K, Morrissey DJ, Naviliat-Cuncic O, Redshaw M, Ringle R, Sandler R, Schwarz S, Sumithrarachchi CS, Valverde AA, Villari AC.

Phys Rev Lett. 2016 Jan 8;116(1):012501. doi: 10.1103/PhysRevLett.116.012501. Epub 2016 Jan 6.

PMID:
26799013
40.

Outcomes of Respiratory Syncytial Virus Immunoprophylaxis in Infants Using an Abbreviated Dosing Regimen of Palivizumab.

Lavoie PM, Solimano A, Taylor R, Kwan E, Claydon J, Turvey SE, Marr N.

JAMA Pediatr. 2016 Feb;170(2):174-6. doi: 10.1001/jamapediatrics.2015.3235. No abstract available.

41.

Enhancing NMR Prediction for Organic Compounds Using Molecular Dynamics.

Kwan EE, Liu RY.

J Chem Theory Comput. 2015 Nov 10;11(11):5083-9. doi: 10.1021/acs.jctc.5b00856. Epub 2015 Oct 14.

PMID:
26574306
42.

Aganglionosis with the absence of hypertrophied nerve fibres predicts disease proximal to rectosigmoid colon.

Narayanan SK, Soundappan SS, Kwan E, Cohen RC, Charlton A, Cass DT.

Pediatr Surg Int. 2016 Mar;32(3):221-6. doi: 10.1007/s00383-015-3835-4. Epub 2015 Nov 2.

PMID:
26527582
43.

A Randomized Controlled Trial of the Use of Oral Glucose with or without Gentle Facilitated Tucking of Infants during Neonatal Echocardiography.

Lavoie PM, Stritzke A, Ting J, Jabr M, Jain A, Kwan E, Chakkarapani E, Brooks P, Brant R, McNamara PJ, Holsti L.

PLoS One. 2015 Oct 23;10(10):e0141015. doi: 10.1371/journal.pone.0141015. eCollection 2015.

44.

Patterns of care for metastatic renal cell carcinoma in Australia.

Day D, Kanjanapan Y, Kwan E, Yip D, Lawrentschuk N, Andrews M, Davis ID, Azad AA, Rosenthal M, Wong S, Johnstone A, Gibbs P, Tran B.

BJU Int. 2015 Oct;116 Suppl 3:36-41. doi: 10.1111/bju.13176. Epub 2015 Jul 21.

45.

Oral glucose during targeted neonatal echocardiography: is it useful?

Lavoie PM, Stritzke A, Ting J, Jabr M, Jain A, Kwan E, Chakkarapani E, Brooks P, Brant R, McNamara PJ, Holsti L.

Arch Dis Child Fetal Neonatal Ed. 2015 Jul;100(4):F374-5. doi: 10.1136/archdischild-2015-308191. Epub 2015 Jun 8. No abstract available.

46.

One-dose vaccination associated with attenuated disease severity of adolescent and adult varicella cases in Beijing's Fengtai District.

Zhang X, Yu Y, Zhang J, Kwan EP, Huang S, Wang Z, Zhang J, Peng X, Yan Y, Zhang L, Luo Y, Han S, Han X, Liu G, Liu F, Zhao J, He Y.

Hum Vaccin Immunother. 2014;10(8):2417-20. doi: 10.4161/hv.29140. Erratum in: Hum Vaccin Immunother. 2014;10(9):2775.

47.

Pharmacokinetics of gentamicin in newborns with moderate-to-severe hypoxic-ischemic encephalopathy undergoing therapeutic hypothermia.

Ting JY, Kwan E, McDougal A, Osiovich H.

Indian J Pediatr. 2015 Feb;82(2):119-25. doi: 10.1007/s12098-014-1527-z. Epub 2014 Jul 29.

PMID:
25070069
48.

Assessment and management of falls in older people.

Kwan E, Straus SE.

CMAJ. 2014 Nov 4;186(16):E610-21. doi: 10.1503/cmaj.131330. Epub 2014 Jun 30. Review. No abstract available.

49.

On Johnson's (2000) Relative Weights Method for Assessing Variable Importance: A Reanalysis.

Thomas DR, Zumbo BD, Kwan E, Schweitzer L.

Multivariate Behav Res. 2014 Jul-Aug;49(4):329-38. doi: 10.1080/00273171.2014.905766.

PMID:
26765801
50.

Cardioprotective trafficking of caveolin to mitochondria is Gi-protein dependent.

Wang J, Schilling JM, Niesman IR, Headrick JP, Finley JC, Kwan E, Patel PM, Head BP, Roth DM, Yue Y, Patel HH.

Anesthesiology. 2014 Sep;121(3):538-48. doi: 10.1097/ALN.0000000000000295.

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