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The Association between Mortality-to-Incidence Ratios and Health Expenditures in Brain and Nervous System Cancers.

Lee TH, Sung WW, Chan L, Lee HL, Chen SL, Huang YH, Kwan AL.

Int J Environ Res Public Health. 2019 Jul 31;16(15). pii: E2739. doi: 10.3390/ijerph16152739.


Predictive Factors of 2-Year Postoperative Outcomes in Patients with Spontaneous Cerebellar Hemorrhage.

Lee TH, Huang YH, Su TM, Chen CF, Lu CH, Lee HL, Tsai HP, Sung WW, Kwan AL.

J Clin Med. 2019 Jun 8;8(6). pii: E818. doi: 10.3390/jcm8060818.


Glycine receptors expression in rat spinal cord and dorsal root ganglion in prostaglandin E2 intrathecal injection models.

Wang HC, Cheng KI, Chen PR, Tseng KY, Kwan AL, Chang LL.

BMC Neurosci. 2018 Nov 9;19(1):72. doi: 10.1186/s12868-018-0470-8.


Radiation Exposure to the Sacroiliac Joint From Low-Dose CT Compared With Radiography.

Chahal BS, Kwan ALC, Dhillon SS, Olubaniyi BO, Jhiangri GS, Neilson MM, Lambert RGW.

AJR Am J Roentgenol. 2018 Nov;211(5):1058-1062. doi: 10.2214/AJR.18.19678. Epub 2018 Sep 12.


Vascular adhesion protein-1 as indicator of breast cancer tumor aggressiveness and invasiveness.

Lai YC, Chang SJ, Kostoro J, Kwan AL, Chai CY.

APMIS. 2018 Sep;126(9):755-761. doi: 10.1111/apm.12885.


High-level Sp1 is Associated with Proliferation, Invasion, and Poor Prognosis in Astrocytoma.

Chen YT, Tsai HP, Wu CC, Chen CY, Chai CY, Kwan AL.

Pathol Oncol Res. 2019 Jul;25(3):1003-1013. doi: 10.1007/s12253-018-0422-8. Epub 2018 Jun 9.


Correction: Osteoporosis Self-Assessment Tool for Asians Can Predict Neurologic Prognosis in Patients with Isolated Moderate Traumatic Brain Injury.

Chao CH, Su YF, Chan HM, Huang SL, Lin CL, Kwan AL, Lou YT, Chen CW.

PLoS One. 2018 Jun 11;13(6):e0198986. doi: 10.1371/journal.pone.0198986. eCollection 2018.


Erythropoietin attenuates motor neuron programmed cell death in a burn animal model.

Wu SH, Lu IC, Lee SS, Kwan AL, Chai CY, Huang SH.

PLoS One. 2018 Jan 31;13(1):e0190039. doi: 10.1371/journal.pone.0190039. eCollection 2018.


Overexpression of Fli-1 in astrocytoma is associated with poor prognosis.

Tsai HP, Tsai TH, Hsieh YJ, Chen YT, Lee CL, Tsai YC, She TC, Lin CL, Chai CY, Kwan AL.

Oncotarget. 2017 Apr 25;8(17):29174-29186. doi: 10.18632/oncotarget.16303.


Combined Genetic Biomarkers and Betel Quid Chewing for Identifying High-Risk Group for Oral Cancer Occurrence.

Chung CM, Lee CH, Chen MK, Lee KW, Lan CE, Kwan AL, Tsai MH, Ko YC.

Cancer Prev Res (Phila). 2017 Jun;10(6):355-362. doi: 10.1158/1940-6207.CAPR-16-0259. Epub 2017 Apr 11.


Hyperglycemia Aggravates Cerebral Vasospasm after Subarachnoid Hemorrhage in a Rat Model.

Huang YH, Chung CL, Tsai HP, Wu SC, Chang CZ, Chai CY, Lee TC, Kwan AL.

Neurosurgery. 2017 May 1;80(5):809-815. doi: 10.1093/neuros/nyx016.


Intrathecal CGS-26303 Pretreatment Attenuates Spinal Nerve Ligation-Induced Neuropathic Pain in the Spinal Cord.

Wang HC, Cheng KI, Chou CW, Kwan AL, Chang LL.

World Neurosurg. 2016 Jul;91:532-541.e1. doi: 10.1016/j.wneu.2016.02.093. Epub 2016 Mar 4.


Overexpression of vascular adhesion protein-1 is associated with poor prognosis of astrocytomas.

Kostoro J, Chang SJ, Clark Lai YC, Wu CC, Chai CY, Kwan AL.

APMIS. 2016 Jun;124(6):462-8. doi: 10.1111/apm.12525. Epub 2016 Mar 2.


Decreased expression of autophagy protein LC3 and stemness (CD44+/CD24-/low) indicate poor prognosis in triple-negative breast cancer.

Chang SJ, Ou-Yang F, Tu HP, Lin CH, Huang SH, Kostoro J, Hou MF, Chai CY, Kwan AL.

Hum Pathol. 2016 Feb;48:48-55. doi: 10.1016/j.humpath.2015.09.034. Epub 2015 Oct 26.


The Role of Serial Oxidative Stress Levels in Acute Traumatic Brain Injury and as Predictors of Outcome.

Wang HC, Lin YJ, Shih FY, Chang HW, Su YJ, Cheng BC, Su CM, Tsai NW, Chang YT, Kwan AL, Lu CH.

World Neurosurg. 2016 Mar;87:463-70. doi: 10.1016/j.wneu.2015.10.010. Epub 2015 Oct 23.


Fat Grafting in Burn Scar Alleviates Neuropathic Pain via Anti-Inflammation Effect in Scar and Spinal Cord.

Huang SH, Wu SH, Lee SS, Chang KP, Chai CY, Yeh JL, Lin SD, Kwan AL, David Wang HM, Lai CS.

PLoS One. 2015 Sep 14;10(9):e0137563. doi: 10.1371/journal.pone.0137563. eCollection 2015.


Osteoporosis Self-Assessment Tool for Asians Can Predict Neurologic Prognosis in Patients with Isolated Moderate Traumatic Brain Injury.

Chao CH, Su YF, Chan HM, Huang SL, Lin CL, Kwan AL, Lou YT, Chen CW.

PLoS One. 2015 Jul 17;10(7):e0132685. doi: 10.1371/journal.pone.0132685. eCollection 2015. Erratum in: PLoS One. 2018 Jun 11;13(6):e0198986.


A purine antimetabolite attenuates toll-like receptor-2, -4, and subarachnoid hemorrhage-induced brain apoptosis.

Chang CZ, Wu SC, Kwan AL.

J Surg Res. 2015 Dec;199(2):676-87. doi: 10.1016/j.jss.2015.06.011. Epub 2015 Jun 12.


Autologous adipose-derived stem cells attenuate muscular atrophy and protect spinal cord ventral horn motor neurons in an animal model of burn injury.

Wu SH, Huang SH, Lo YC, Chai CY, Lee SS, Chang KP, Lin SD, Lai CS, Yeh JL, Kwan AL.

Cytotherapy. 2015 Aug;17(8):1066-75. doi: 10.1016/j.jcyt.2015.03.687.


Magnesium Lithospermate B Implicates 3'-5'-Cyclic Adenosine Monophosphate/Protein Kinase A Pathway and N-Methyl-d-Aspartate Receptors in an Experimental Traumatic Brain Injury.

Chang CZ, Wu SC, Kwan AL, Lin CL.

World Neurosurg. 2015 Oct;84(4):954-63. doi: 10.1016/j.wneu.2015.05.075. Epub 2015 Jun 18.


Nucleophosmin overexpression is associated with poor survival in astrocytoma.

Kuo YH, Chen YT, Tsai HP, Chai CY, Kwan AL.

APMIS. 2015 Jun;123(6):515-22. doi: 10.1111/apm.12381. Epub 2015 Apr 23.


Preconditioning with pitavastatin, an HMG-CoA reductase inhibitor, attenuates C-Jun N-terminal kinase activation in experimental subarachnoid hemorrhage-induced apoptosis.

Chang CZ, Wu SC, Kwan AL, Lin CL.

Acta Neurochir (Wien). 2015 Jun;157(6):1031-41; discussion 1041. doi: 10.1007/s00701-015-2399-3. Epub 2015 Apr 19.


Curcumin, encapsulated in nano-sized PLGA, down-regulates nuclear factor κB (p65) and subarachnoid hemorrhage induced early brain injury in a rat model.

Chang CZ, Wu SC, Lin CL, Kwan AL.

Brain Res. 2015 May 22;1608:215-24. doi: 10.1016/j.brainres.2015.02.039. Epub 2015 Mar 5.


Third-degree hindpaw burn injury induced apoptosis of lumbar spinal cord ventral horn motor neurons and sciatic nerve and muscle atrophy in rats.

Wu SH, Huang SH, Cheng KI, Chai CY, Yeh JL, Wu TC, Hsu YC, Kwan AL.

Biomed Res Int. 2015;2015:372819. doi: 10.1155/2015/372819. Epub 2015 Jan 28.


A modified compression model of spinal cord injury in rats: functional assessment and the expression of nitric oxide synthases.

Su YF, Lin CL, Lee KS, Tsai TH, Wu SC, Hwang SL, Chen SC, Kwan AL.

Spinal Cord. 2015 Jun;53(6):432-5. doi: 10.1038/sc.2014.245. Epub 2015 Feb 3.


Purpurogallin, a natural phenol, attenuates high-mobility group box 1 in subarachnoid hemorrhage induced vasospasm in a rat model.

Chang CZ, Lin CL, Wu SC, Kwan AL.

Int J Vasc Med. 2014;2014:254270. doi: 10.1155/2014/254270. Epub 2014 Nov 17.


Bacterial resistance to leucyl-tRNA synthetase inhibitor GSK2251052 develops during treatment of complicated urinary tract infections.

O'Dwyer K, Spivak AT, Ingraham K, Min S, Holmes DJ, Jakielaszek C, Rittenhouse S, Kwan AL, Livi GP, Sathe G, Thomas E, Van Horn S, Miller LA, Twynholm M, Tomayko J, Dalessandro M, Caltabiano M, Scangarella-Oman NE, Brown JR.

Antimicrob Agents Chemother. 2015 Jan;59(1):289-98. doi: 10.1128/AAC.03774-14. Epub 2014 Oct 27.


Clinical Pathway in the Treatment of Nocardial Brain Abscesses following Systemic Infections.

Zheng YC, Wang TL, Hsu JC, Hsu YH, Hsu WH, Wang CL, Kwan AL, Lin CL.

Case Rep Neurol Med. 2014;2014:584934. doi: 10.1155/2014/584934. Epub 2014 Aug 28.


Glycyrrhizin attenuates Toll like receptor-2, -4 and experimental vasospasm in a rat model.

Chang CZ, Wu SC, Kwan AL.

J Immunol Res. 2014;2014:740549. doi: 10.1155/2014/740549. Epub 2014 Jul 23.


Alteration of basilar artery rho-kinase and soluble guanylyl cyclase protein expression in a rat model of cerebral vasospasm following subarachnoid hemorrhage.

Wang CJ, Lee PY, Wu BN, Wu SC, Loh JK, Tsai HP, Chung CL, Kassell NF, Kwan AL.

Biomed Res Int. 2014;2014:531508. doi: 10.1155/2014/531508. Epub 2014 Jun 1.


Characterization of pituitary tumor transforming gene in meningiomas.

Zhang H, Du R, Huang YH, She L, Dong L, Wang X, Kwan AL.

Clin Neurol Neurosurg. 2014 Jul;122:120-3. doi: 10.1016/j.clineuro.2014.04.028. Epub 2014 May 6. Erratum in: Clin Neurol Neurosurg. 2014 Sep;124:194.


Differential hypermethylation of death-associated protein kinase promoter in central neurocytoma and oligodendroglioma.

Chung CL, Tsai HP, Tsai CY, Chen WT, Lieu AS, Wang CJ, Sheehan J, Chai CY, Kwan AL.

Biomed Res Int. 2014;2014:506458. doi: 10.1155/2014/506458. Epub 2014 Apr 27.


Predictors of memory and processing speed dysfunctions after traumatic brain injury.

Winardi W, Kwan AL, Wang TL, Su YF, Yen CP, Tsai HP, Sheehan J, Su CY.

Biomed Res Int. 2014;2014:129796. doi: 10.1155/2014/129796. Epub 2014 Apr 29.


Autologous fat grafting alleviates burn-induced neuropathic pain in rats.

Huang SH, Wu SH, Chang KP, Cheng KI, Lee SS, Kwan AL, Yeh JL, Tsai HP, Lin SD, Lai CS.

Plast Reconstr Surg. 2014 Jun;133(6):1396-405. doi: 10.1097/PRS.0000000000000169.


Serial serum leukocyte apoptosis levels as predictors of outcome in acute traumatic brain injury.

Wang HC, Yang TM, Lin YJ, Chen WF, Ho JT, Lin YT, Kwan AL, Lu CH.

Biomed Res Int. 2014;2014:720870. doi: 10.1155/2014/720870. Epub 2014 Apr 17.


Surgical strategies and outcomes of spinal ependymomas of different lengths: analysis of 210 patients: clinical article.

Li TY, Chu JS, Xu YL, Yang J, Wang J, Huang YH, Kwan AL, Wang GH.

J Neurosurg Spine. 2014 Aug;21(2):249-59. doi: 10.3171/2014.3.SPINE13481. Epub 2014 May 16.


Magnesium lithospermate B, an active extract of Salvia miltiorrhiza, mediates sGC/cGMP/PKG translocation in experimental vasospasm.

Chang CZ, Wu SC, Kwan AL.

Biomed Res Int. 2014;2014:272101. doi: 10.1155/2014/272101. Epub 2014 Apr 2. Erratum in: Biomed Res Int. 2016;2016:6240750.


Adenoviral-mediated glial cell line-derived neurotrophic factor gene transfer has a protective effect on sciatic nerve following constriction-induced spinal cord injury.

Chou AK, Yang MC, Tsai HP, Chai CY, Tai MH, Kwan AL, Hong YR.

PLoS One. 2014 Mar 18;9(3):e92264. doi: 10.1371/journal.pone.0092264. eCollection 2014.


Association of Aurora A and gamma-tubulin expression in astrocytomas and patient survival.

Tsai HP, Tsai CY, Lieu AS, Chai CY, Kwan AL, Howng SL, Loh JK.

Neurol Res. 2014 Aug;36(8):746-51. doi: 10.1179/1743132813Y.0000000310. Epub 2014 Jan 14.


Serial plasma deoxyribonucleic acid levels as predictors of outcome in acute traumatic brain injury.

Wang HC, Lin YJ, Tsai NW, Su BY, Kung CT, Chen WF, Kwan AL, Lu CH.

J Neurotrauma. 2014 Jun 1;31(11):1039-45. doi: 10.1089/neu.2013.3070. Epub 2014 Mar 31.


Application of quinidine on rat sciatic nerve decreases the amplitude and increases the latency of evoked responses.

Cheng KI, Lin IL, Chang LL, Jou IM, Lai CS, Wang JJ, Wang HC, Kwan AL.

J Anesth. 2014 Aug;28(4):559-68. doi: 10.1007/s00540-013-1754-x. Epub 2013 Dec 15.


Reduction cranioplasty with the aid of simulated computer imaging for the treatment of hydrocephalic macrocephaly.

Shen SH, Kwan AL, Wang BL, Guo JF, Tan GW, Chen SF, Liu XY, Liu F, Cai M, Wang ZX.

J Neurosurg Pediatr. 2014 Feb;13(2):133-9. doi: 10.3171/2013.10.PEDS12573. Epub 2013 Nov 29.


Bioenergetic failure correlates with autophagy and apoptosis in rat liver following silver nanoparticle intraperitoneal administration.

Lee TY, Liu MS, Huang LJ, Lue SI, Lin LC, Kwan AL, Yang RC.

Part Fibre Toxicol. 2013 Aug 19;10:40. doi: 10.1186/1743-8977-10-40.


TGM2 inhibition attenuates ID1 expression in CD44-high glioma-initiating cells.

Fu J, Yang QY, Sai K, Chen FR, Pang JC, Ng HK, Kwan AL, Chen ZP.

Neuro Oncol. 2013 Oct;15(10):1353-65. doi: 10.1093/neuonc/not079. Epub 2013 Jul 21.

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