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Inhibitory regulation of calcium transients in prefrontal dendritic spines is compromised by a nonsense Shank3 mutation.

Ali F, Shao LX, Gerhard DM, Sweasy K, Pothula S, Pittenger C, Duman RS, Kwan AC.

Mol Psychiatry. 2020 Mar 11. doi: 10.1038/s41380-020-0708-6. [Epub ahead of print]


Ketamine disinhibits dendrites and enhances calcium signals in prefrontal dendritic spines.

Ali F, Gerhard DM, Sweasy K, Pothula S, Pittenger C, Duman RS, Kwan AC.

Nat Commun. 2020 Jan 7;11(1):72. doi: 10.1038/s41467-019-13809-8.


Parvalbumin-Positive Neuron Loss and Amyloid-β Deposits in the Frontal Cortex of Alzheimer's Disease-Related Mice.

Ali F, Baringer SL, Neal A, Choi EY, Kwan AC.

J Alzheimers Dis. 2019;72(4):1323-1339. doi: 10.3233/JAD-181190.


Interpreting in vivo calcium signals from neuronal cell bodies, axons, and dendrites: a review.

Ali F, Kwan AC.

Neurophotonics. 2020 Jan;7(1):011402. doi: 10.1117/1.NPh.7.1.011402. Epub 2019 Jul 30. Review.


Consensus statements on diagnosis and management of chronic idiopathic constipation in adults in Hong Kong.

Wu JCY, Chan AOO, Cheung TK, Kwan ACP, Leung VKS, Sze WC, Tan VPY.

Hong Kong Med J. 2019 Apr;25(2):142-148. doi: 10.12809/hkmj187692. No abstract available.


Relationship between changes in pericoronary adipose tissue attenuation and coronary plaque burden quantified from coronary computed tomography angiography.

Goeller M, Tamarappoo BK, Kwan AC, Cadet S, Commandeur F, Razipour A, Slomka PJ, Gransar H, Chen X, Otaki Y, Friedman JD, Cao JJ, Albrecht MH, Bittner DO, Marwan M, Achenbach S, Berman DS, Dey D.

Eur Heart J Cardiovasc Imaging. 2019 Jun 1;20(6):636-643. doi: 10.1093/ehjci/jez013.


Enhanced Population Coding for Rewarded Choices in the Medial Frontal Cortex of the Mouse.

Siniscalchi MJ, Wang H, Kwan AC.

Cereb Cortex. 2019 Sep 13;29(10):4090-4106. doi: 10.1093/cercor/bhy292.


Same lesson, varied choices by frontal cortex.

Atilgan H, Kwan AC.

Nat Neurosci. 2018 Dec;21(12):1648-1650. doi: 10.1038/s41593-018-0282-2. No abstract available.


Pericoronary Adipose Tissue Computed Tomography Attenuation and High-Risk Plaque Characteristics in Acute Coronary Syndrome Compared With Stable Coronary Artery Disease.

Goeller M, Achenbach S, Cadet S, Kwan AC, Commandeur F, Slomka PJ, Gransar H, Albrecht MH, Tamarappoo BK, Berman DS, Marwan M, Dey D.

JAMA Cardiol. 2018 Sep 1;3(9):858-863. doi: 10.1001/jamacardio.2018.1997.


The current treatment landscape of irritable bowel syndrome in adults in Hong Kong: consensus statements.

Wu JC, Chan AO, Chan YW, Cheung GC, Cheung TK, Kwan AC, Leung VK, Mak AD, Sze WC, Wong R.

Hong Kong Med J. 2017 Dec;23(6):641-7. doi: 10.12809/hkmj177060.


Bridging the gap for lipid lowering therapy: plaque regression, coronary computed tomographic angiography, and imaging-guided personalized medicine.

Kwan AC, Aronis KN, Sandfort V, Blumenthal RS, Bluemke DA.

Expert Rev Cardiovasc Ther. 2017 Jul;15(7):547-558. doi: 10.1080/14779072.2017.1348228. Epub 2017 Jul 6. Review.


Targeted two-photon chemical apoptotic ablation of defined cell types in vivo.

Hill RA, Damisah EC, Chen F, Kwan AC, Grutzendler J.

Nat Commun. 2017 Jun 16;8:15837. doi: 10.1038/ncomms15837.


Automatic high-resolution infarct detection using volumetric multiphase dual-energy CT.

Sandfort V, Kwan AC, Elumogo C, Vigneault DM, Symons R, Pourmorteza A, Rice K, Davies-Venn C, Ahlman MA, Liu CY, Zimmerman SL, Bluemke DA.

J Cardiovasc Comput Tomogr. 2017 Jul - Aug;11(4):288-294. doi: 10.1016/j.jcct.2017.04.006. Epub 2017 Apr 18.


Secondary Motor Cortex: Where 'Sensory' Meets 'Motor' in the Rodent Frontal Cortex.

Barthas F, Kwan AC.

Trends Neurosci. 2017 Mar;40(3):181-193. doi: 10.1016/j.tins.2016.11.006. Epub 2016 Dec 22. Review.


Fast and slow transitions in frontal ensemble activity during flexible sensorimotor behavior.

Siniscalchi MJ, Phoumthipphavong V, Ali F, Lozano M, Kwan AC.

Nat Neurosci. 2016 Sep;19(9):1234-42. doi: 10.1038/nn.4342. Epub 2016 Jul 11.


Sitting at patients' bedsides may improve patients' perceptions of physician communication skills.

Merel SE, McKinney CM, Ufkes P, Kwan AC, White AA.

J Hosp Med. 2016 Dec;11(12):865-868. doi: 10.1002/jhm.2634. Epub 2016 Jul 5.


Longitudinal Effects of Ketamine on Dendritic Architecture In Vivo in the Mouse Medial Frontal Cortex.

Phoumthipphavong V, Barthas F, Hassett S, Kwan AC.

eNeuro. 2016 Apr 4;3(2). pii: ENEURO.0133-15.2016. doi: 10.1523/ENEURO.0133-15.2016. eCollection 2016 Mar-Apr.


Promoting Sex Education Among Teenagers Through an Interactive Game: Reasons for Success and Implications.

Chu SK, Kwan AC, Reynolds R, Mellecker RR, Tam F, Lee G, Hong A, Leung CY.

Games Health J. 2015 Jun;4(3):168-74. doi: 10.1089/g4h.2014.0059. Epub 2015 Feb 6.


Coronary Plaque Burden at Coronary CT Angiography in Asymptomatic Men and Women.

Rodriguez K, Kwan AC, Lai S, Lima JA, Vigneault D, Sandfort V, Pattanayak P, Ahlman MA, Mallek M, Sibley CT, Bluemke DA.

Radiology. 2015 Oct;277(1):73-80. doi: 10.1148/radiol.2015142551. Epub 2015 Jun 2.


Assessment of atherosclerosis in chronic granulomatous disease.

Sibley CT, Estwick T, Zavodni A, Huang CY, Kwan AC, Soule BP, Long Priel DA, Remaley AT, Rudman Spergel AK, Turkbey EB, Kuhns DB, Holland SM, Malech HL, Zarember KA, Bluemke DA, Gallin JI.

Circulation. 2014 Dec 2;130(23):2031-9. doi: 10.1161/CIRCULATIONAHA.113.006824. Epub 2014 Sep 19.


Coronary artery plaque volume and obesity in patients with diabetes: the factor-64 study.

Kwan AC, May HT, Cater G, Sibley CT, Rosen BD, Lima JA, Rodriguez K, Lappe DL, Muhlestein JB, Anderson JL, Bluemke DA.

Radiology. 2014 Sep;272(3):690-9. doi: 10.1148/radiol.14140611. Epub 2014 Apr 22.


Interneuron subtypes and orientation tuning.

Lee SH, Kwan AC, Dan Y.

Nature. 2014 Apr 3;508(7494):E1-2. doi: 10.1038/nature13128. No abstract available.


Fast modulation of visual perception by basal forebrain cholinergic neurons.

Pinto L, Goard MJ, Estandian D, Xu M, Kwan AC, Lee SH, Harrison TC, Feng G, Dan Y.

Nat Neurosci. 2013 Dec;16(12):1857-1863. doi: 10.1038/nn.3552. Epub 2013 Oct 27.


Effectiveness of a workplace training programme in improving social, communication and emotional skills for adults with autism and intellectual disability in Hong Kong--a pilot study.

Liu KP, Wong D, Chung AC, Kwok N, Lam MK, Yuen CM, Arblaster K, Kwan AC.

Occup Ther Int. 2013 Dec;20(4):198-204. doi: 10.1002/oti.1356. Epub 2013 Jul 16.


Beyond Coronary Stenosis: Coronary Computed Tomographic Angiography for the Assessment of Atherosclerotic Plaque Burden.

Kwan AC, Cater G, Vargas J, Bluemke DA.

Curr Cardiovasc Imaging Rep. 2013 Apr 1;6(2):89-101. Epub 2013 Jan 22.


Activation of specific interneurons improves V1 feature selectivity and visual perception.

Lee SH, Kwan AC, Zhang S, Phoumthipphavong V, Flannery JG, Masmanidis SC, Taniguchi H, Huang ZJ, Zhang F, Boyden ES, Deisseroth K, Dan Y.

Nature. 2012 Aug 16;488(7411):379-83. doi: 10.1038/nature11312.


Dissection of cortical microcircuits by single-neuron stimulation in vivo.

Kwan AC, Dan Y.

Curr Biol. 2012 Aug 21;22(16):1459-67. doi: 10.1016/j.cub.2012.06.007. Epub 2012 Jun 28.


Delayed pneumothorax after bronchoscopy in a lung transplant patient.

Kwan AC, Pipavath S, Leary PJ, Kicska G.

Respir Care. 2013 Mar;58(3):e18-9. doi: 10.4187/respcare.01842.


Live imaging of newly formed lymphatic vessels in the cornea.

Yuen D, Wu X, Kwan AC, Ledue J, Zhang H, Ecoiffier T, Pytowski B, Chen L.

Cell Res. 2011 Dec;21(12):1745-9. doi: 10.1038/cr.2011.178. Epub 2011 Nov 15. No abstract available.


Dopamine-induced oscillations of the pyloric pacemaker neuron rely on release of calcium from intracellular stores.

Kadiri LR, Kwan AC, Webb WW, Harris-Warrick RM.

J Neurophysiol. 2011 Sep;106(3):1288-98. doi: 10.1152/jn.00456.2011. Epub 2011 Jun 15.


Enhancing collection efficiency in large field of view multiphoton microscopy.

McMullen JD, Kwan AC, Williams RM, Zipfel WR.

J Microsc. 2011 Feb;241(2):119-24. doi: 10.1111/j.1365-2818.2010.03419.x.


Spatiotemporal dynamics of rhythmic spinal interneurons measured with two-photon calcium imaging and coherence analysis.

Kwan AC, Dietz SB, Zhong G, Harris-Warrick RM, Webb WW.

J Neurophysiol. 2010 Dec;104(6):3323-33. doi: 10.1152/jn.00679.2010. Epub 2010 Sep 22.


Toward reconstructing spike trains from large-scale calcium imaging data.

Kwan AC.

HFSP J. 2010 Feb;4(1):1-5. doi: 10.2976/1.3284977. Epub 2010 Jan 22.


Electrophysiological characterization of V2a interneurons and their locomotor-related activity in the neonatal mouse spinal cord.

Zhong G, Droho S, Crone SA, Dietz S, Kwan AC, Webb WW, Sharma K, Harris-Warrick RM.

J Neurosci. 2010 Jan 6;30(1):170-82. doi: 10.1523/JNEUROSCI.4849-09.2010.


Activity of Hb9 interneurons during fictive locomotion in mouse spinal cord.

Kwan AC, Dietz SB, Webb WW, Harris-Warrick RM.

J Neurosci. 2009 Sep 16;29(37):11601-13. doi: 10.1523/JNEUROSCI.1612-09.2009.


Second opinions improve ADHD prescribing in a medicaid-insured community population.

Thompson JN, Varley CK, McClellan J, Hilt R, Lee T, Kwan AC, Lee T, Trupin E.

J Am Acad Child Adolesc Psychiatry. 2009 Jul;48(7):740-748. doi: 10.1097/CHI.0b013e3181a2b2ed.


Brachydactyly A-1 mutations restricted to the central region of the N-terminal active fragment of Indian Hedgehog.

Byrnes AM, Racacho L, Grimsey A, Hudgins L, Kwan AC, Sangalli M, Kidd A, Yaron Y, Lau YL, Nikkel SM, Bulman DE.

Eur J Hum Genet. 2009 Sep;17(9):1112-20. doi: 10.1038/ejhg.2009.18. Epub 2009 Mar 11.


What can population calcium imaging tell us about neural circuits?

Kwan AC.

J Neurophysiol. 2008 Dec;100(6):2977-80. doi: 10.1152/jn.91037.2008. Epub 2008 Oct 1. Review.


Polarized microtubule arrays in apical dendrites and axons.

Kwan AC, Dombeck DA, Webb WW.

Proc Natl Acad Sci U S A. 2008 Aug 12;105(32):11370-5. doi: 10.1073/pnas.0805199105. Epub 2008 Aug 5.


Ethnic differences in the relationship between adiponectin and insulin sensitivity in South Asian and Caucasian women.

Martin M, Palaniappan LP, Kwan AC, Reaven GM, Reaven PD.

Diabetes Care. 2008 Apr;31(4):798-801. doi: 10.2337/dc07-1781. Epub 2008 Jan 17. Erratum in: Diabetes Care. 2008 Aug;31(8):1712.


Use of the Interact Short Form as a tool to evaluate emotion of people with profound intellectual disabilities.

Liu KP, Lee T, Yan A, Siu CW, Choy FW, Leung KL, Siu TY, Kwan AC.

J Intellect Disabil Res. 2007 Nov;51(Pt 11):884-91.


Lipoprotein abnormalities are associated with insulin resistance in South Asian Indian women.

Palaniappan LP, Kwan AC, Abbasi F, Lamendola C, McLaughlin TL, Reaven GM.

Metabolism. 2007 Jul;56(7):899-904.


Cloning and characterization of the Pichia pastoris MET2 gene as a selectable marker.

Thor D, Xiong S, Orazem CC, Kwan AC, Cregg JM, Lin-Cereghino J, Lin-Cereghino GP.

FEMS Yeast Res. 2005 Jul;5(10):935-42.


Severe acute respiratory syndrome-related diarrhea.

Kwan AC, Chau TN, Tong WL, Tsang OT, Tso EY, Chiu MC, Yu WC, Lai TS.

J Gastroenterol Hepatol. 2005 Apr;20(4):606-10.


Clinical significance of hepatic derangement in severe acute respiratory syndrome.

Chan HL, Kwan AC, To KF, Lai ST, Chan PK, Leung WK, Lee N, Wu A, Sung JJ.

World J Gastroenterol. 2005 Apr 14;11(14):2148-53.


Normal colon transit time in healthy Chinese adults in Hong Kong.

Chan YK, Kwan AC, Yuen H, Yeung YW, Lai KC, Wu J, Wong GS, Leung CM, Cheung WC, Wong CK.

J Gastroenterol Hepatol. 2004 Nov;19(11):1270-5.


Validation of Rome II criteria for functional gastrointestinal disorders by factor analysis of symptoms in Asian patient sample.

Kwan AC, Bao T, Chakkaphak S, Chang FY, Ke M, Law NM, Leelakusolvong S, Luo JY, Manan C, Park HJ, Piyaniran W, Qureshi A, Long T, Xu GM, Xu L, Yuen H.

J Gastroenterol Hepatol. 2003 Jul;18(7):796-802.


Prevalence of irritable bowel syndrome in Hong Kong.

Kwan AC, Hu WH, Chan YK, Yeung YW, Lai TS, Yuen H.

J Gastroenterol Hepatol. 2002 Nov;17(11):1180-6.


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