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Items: 1 to 50 of 110

1.

Impaired SMAD1/5 Mechanotransduction and Cx37 (Connexin37) Expression Enable Pathological Vessel Enlargement and Shunting.

Peacock HM, Tabibian A, Criem N, Caolo V, Hamard L, Deryckere A, Haefliger JA, Kwak BR, Zwijsen A, Jones EAV.

Arterioscler Thromb Vasc Biol. 2020 Apr;40(4):e87-e104. doi: 10.1161/ATVBAHA.119.313122. Epub 2020 Feb 6.

PMID:
32078368
2.

A Genetic Polymorphism in the Pannexin1 Gene Predisposes for The Development of Endothelial Dysfunction with Increasing BMI.

Molica F, Quercioli A, Montecucco F, Schindler TH, Kwak BR, Morel S.

Biomolecules. 2020 Jan 31;10(2). pii: E208. doi: 10.3390/biom10020208.

3.

Sex-related differences in wall remodeling and intraluminal thrombus resolution in a rat saccular aneurysm model.

Morel S, Karol A, Graf V, Pelli G, Richter H, Sutter E, Braunersreuther V, Frösen J, Bijlenga P, Kwak BR, Nuss KM.

J Neurosurg. 2019 Dec 27:1-14. doi: 10.3171/2019.9.JNS191466. [Epub ahead of print]

PMID:
31881533
4.

ATP amplifies NADPH-dependent and -independent neutrophil extracellular trap formation.

Sofoluwe A, Bacchetta M, Badaoui M, Kwak BR, Chanson M.

Sci Rep. 2019 Nov 12;9(1):16556. doi: 10.1038/s41598-019-53058-9.

5.

Selective inhibition of Panx1 channels decreases hemostasis and thrombosis in vivo.

Molica F, Meens MJ, Pelli G, Hautefort A, Emre Y, Imhof BA, Fontana P, Scemes E, Morel S, Kwak BR.

Thromb Res. 2019 Nov;183:56-62. doi: 10.1016/j.thromres.2019.09.028. Epub 2019 Oct 18.

6.

Artery-Associated Sympathetic Innervation Drives Rhythmic Vascular Inflammation of Arteries and Veins.

de Juan A, Ince LM, Pick R, Chen CS, Molica F, Zuchtriegel G, Wang C, Zhang D, Druzd D, Hessenauer MET, Pelli G, Kolbe I, Oster H, Prophete C, Hergenhan SM, Albrecht U, Ripperger J, Montanez E, Reichel CA, Soehnlein O, Kwak BR, Frenette PS, Scheiermann C.

Circulation. 2019 Sep 24;140(13):1100-1114. doi: 10.1161/CIRCULATIONAHA.119.040232. Epub 2019 Aug 12.

PMID:
31401849
7.

Biological Functions of Connexin43 Beyond Intercellular Communication.

Martins-Marques T, Ribeiro-Rodrigues T, Batista-Almeida D, Aasen T, Kwak BR, Girao H.

Trends Cell Biol. 2019 Oct;29(10):835-847. doi: 10.1016/j.tcb.2019.07.001. Epub 2019 Jul 26. Review.

PMID:
31358412
8.

Chronic fructose renders pancreatic β-cells hyper-responsive to glucose-stimulated insulin secretion through extracellular ATP signaling.

Bartley C, Brun T, Oberhauser L, Grimaldi M, Molica F, Kwak BR, Bosco D, Chanson M, Maechler P.

Am J Physiol Endocrinol Metab. 2019 Jul 1;317(1):E25-E41. doi: 10.1152/ajpendo.00456.2018. Epub 2019 Mar 26.

PMID:
30912960
9.

Disturbed flow induces a sustained, stochastic NF-κB activation which may support intracranial aneurysm growth in vivo.

Baeriswyl DC, Prionisti I, Peach T, Tsolkas G, Chooi KY, Vardakis J, Morel S, Diagbouga MR, Bijlenga P, Cuhlmann S, Evans P, Kwak BR, Ventikos Y, Krams R.

Sci Rep. 2019 Mar 18;9(1):4738. doi: 10.1038/s41598-019-40959-y.

10.

KLF4-Induced Connexin40 Expression Contributes to Arterial Endothelial Quiescence.

Denis JF, Diagbouga MR, Molica F, Hautefort A, Linnerz T, Watanabe M, Lemeille S, Bertrand JY, Kwak BR.

Front Physiol. 2019 Feb 12;10:80. doi: 10.3389/fphys.2019.00080. eCollection 2019.

11.

An Overview of the Focus of the International Gap Junction Conference 2017 and Future Perspectives.

Martin PE, Kwak BR.

Int J Mol Sci. 2018 Sep 18;19(9). pii: E2823. doi: 10.3390/ijms19092823.

12.

Role of hemodynamics in initiation/growth of intracranial aneurysms.

Diagbouga MR, Morel S, Bijlenga P, Kwak BR.

Eur J Clin Invest. 2018 Sep;48(9):e12992. doi: 10.1111/eci.12992. Epub 2018 Jul 20. Review.

PMID:
29962043
13.

Connexins and Pannexins in Vascular Function and Disease.

Molica F, Figueroa XF, Kwak BR, Isakson BE, Gibbins JM.

Int J Mol Sci. 2018 Jun 5;19(6). pii: E1663. doi: 10.3390/ijms19061663. Review.

14.

Consensus guidelines for the use and interpretation of angiogenesis assays.

Nowak-Sliwinska P, Alitalo K, Allen E, Anisimov A, Aplin AC, Auerbach R, Augustin HG, Bates DO, van Beijnum JR, Bender RHF, Bergers G, Bikfalvi A, Bischoff J, Böck BC, Brooks PC, Bussolino F, Cakir B, Carmeliet P, Castranova D, Cimpean AM, Cleaver O, Coukos G, Davis GE, De Palma M, Dimberg A, Dings RPM, Djonov V, Dudley AC, Dufton NP, Fendt SM, Ferrara N, Fruttiger M, Fukumura D, Ghesquière B, Gong Y, Griffin RJ, Harris AL, Hughes CCW, Hultgren NW, Iruela-Arispe ML, Irving M, Jain RK, Kalluri R, Kalucka J, Kerbel RS, Kitajewski J, Klaassen I, Kleinmann HK, Koolwijk P, Kuczynski E, Kwak BR, Marien K, Melero-Martin JM, Munn LL, Nicosia RF, Noel A, Nurro J, Olsson AK, Petrova TV, Pietras K, Pili R, Pollard JW, Post MJ, Quax PHA, Rabinovich GA, Raica M, Randi AM, Ribatti D, Ruegg C, Schlingemann RO, Schulte-Merker S, Smith LEH, Song JW, Stacker SA, Stalin J, Stratman AN, Van de Velde M, van Hinsbergh VWM, Vermeulen PB, Waltenberger J, Weinstein BM, Xin H, Yetkin-Arik B, Yla-Herttuala S, Yoder MC, Griffioen AW.

Angiogenesis. 2018 Aug;21(3):425-532. doi: 10.1007/s10456-018-9613-x. Review.

15.

Correlating Clinical Risk Factors and Histological Features in Ruptured and Unruptured Human Intracranial Aneurysms: The Swiss AneuX Study.

Morel S, Diagbouga MR, Dupuy N, Sutter E, Braunersreuther V, Pelli G, Corniola M, Gondar R, Jägersberg M, Isidor N, Schaller K, Bochaton-Piallat ML, Bijlenga P, Kwak BR.

J Neuropathol Exp Neurol. 2018 Jul 1;77(7):555-566. doi: 10.1093/jnen/nly031.

16.

Dendritic Cell Migration Toward CCL21 Gradient Requires Functional Cx43.

Ruez R, Dubrot J, Zoso A, Bacchetta M, Molica F, Hugues S, Kwak BR, Chanson M.

Front Physiol. 2018 Mar 27;9:288. doi: 10.3389/fphys.2018.00288. eCollection 2018.

17.

Differential Association of Cx37 and Cx40 Genetic Variants in Atrial Fibrillation with and without Underlying Structural Heart Disease.

Carballo S, Pfenniger A, Carballo D, Garin N, James RW, Mach F, Shah D, Kwak BR.

Int J Mol Sci. 2018 Jan 19;19(1). pii: E295. doi: 10.3390/ijms19010295.

18.

Pannexin1 links lymphatic function to lipid metabolism and atherosclerosis.

Molica F, Meens MJ, Dubrot J, Ehrlich A, Roth CL, Morel S, Pelli G, Vinet L, Braunersreuther V, Ratib O, Chanson M, Hugues S, Scemes E, Kwak BR.

Sci Rep. 2017 Oct 20;7(1):13706. doi: 10.1038/s41598-017-14130-4.

19.

Role of connexin 43 in different forms of intercellular communication - gap junctions, extracellular vesicles and tunnelling nanotubes.

Ribeiro-Rodrigues TM, Martins-Marques T, Morel S, Kwak BR, Girão H.

J Cell Sci. 2017 Nov 1;130(21):3619-3630. doi: 10.1242/jcs.200667. Epub 2017 Oct 12. Review.

20.

Connexins in Cardiovascular and Neurovascular Health and Disease: Pharmacological Implications.

Leybaert L, Lampe PD, Dhein S, Kwak BR, Ferdinandy P, Beyer EC, Laird DW, Naus CC, Green CR, Schulz R.

Pharmacol Rev. 2017 Oct;69(4):396-478. doi: 10.1124/pr.115.012062. Review.

21.

Connexin40 controls endothelial activation by dampening NFκB activation.

Denis JF, Scheckenbach KEL, Pfenniger A, Meens MJ, Krams R, Miquerol L, Taffet S, Chanson M, Delmar M, Kwak BR.

Oncotarget. 2017 Mar 22;8(31):50972-50986. doi: 10.18632/oncotarget.16438. eCollection 2017 Aug 1.

22.

Exosomes secreted by cardiomyocytes subjected to ischaemia promote cardiac angiogenesis.

Ribeiro-Rodrigues TM, Laundos TL, Pereira-Carvalho R, Batista-Almeida D, Pereira R, Coelho-Santos V, Silva AP, Fernandes R, Zuzarte M, Enguita FJ, Costa MC, Pinto-do-Ó P, Pinto MT, Gouveia P, Ferreira L, Mason JC, Pereira P, Kwak BR, Nascimento DS, Girão H.

Cardiovasc Res. 2017 Sep 1;113(11):1338-1350. doi: 10.1093/cvr/cvx118.

PMID:
28859292
23.

Cx47 fine-tunes the handling of serum lipids but is dispensable for lymphatic vascular function.

Meens MJ, Kutkut I, Rochemont V, Dubrot J, Kaladji FR, Sabine A, Lyons O, Hendrikx S, Bernier-Latmani J, Kiefer F, Smith A, Hugues S, Petrova TV, Kwak BR.

PLoS One. 2017 Jul 21;12(7):e0181476. doi: 10.1371/journal.pone.0181476. eCollection 2017.

24.

Human venous valve disease caused by mutations in FOXC2 and GJC2.

Lyons O, Saha P, Seet C, Kuchta A, Arnold A, Grover S, Rashbrook V, Sabine A, Vizcay-Barrena G, Patel A, Ludwinski F, Padayachee S, Kume T, Kwak BR, Brice G, Mansour S, Ostergaard P, Mortimer P, Jeffery S, Brown N, Makinen T, Petrova TV, Modarai B, Smith A.

J Exp Med. 2017 Aug 7;214(8):2437-2452. doi: 10.1084/jem.20160875.

25.
26.

Pannexin- and Connexin-Mediated Intercellular Communication in Platelet Function.

Molica F, Stierlin FB, Fontana P, Kwak BR.

Int J Mol Sci. 2017 Apr 17;18(4). pii: E850. doi: 10.3390/ijms18040850. Review.

27.

Pannexin1 Single Nucleotide Polymorphism and Platelet Reactivity in a Cohort of Cardiovascular Patients.

Stierlin FB, Molica F, Reny JL, Kwak BR, Fontana P.

Cell Commun Adhes. 2017 Dec;23(1):11-15. doi: 10.1080/15419061.2017.1282469.

PMID:
28142297
28.

Connexins and their channels in inflammation.

Willebrords J, Crespo Yanguas S, Maes M, Decrock E, Wang N, Leybaert L, Kwak BR, Green CR, Cogliati B, Vinken M.

Crit Rev Biochem Mol Biol. 2016 Nov/Dec;51(6):413-439. doi: 10.1080/10409238.2016.1204980. Epub 2016 Jul 7. Review.

29.

Central Role of P2Y6 UDP Receptor in Arteriolar Myogenic Tone.

Kauffenstein G, Tamareille S, Prunier F, Roy C, Ayer A, Toutain B, Billaud M, Isakson BE, Grimaud L, Loufrani L, Rousseau P, Abraham P, Procaccio V, Monyer H, de Wit C, Boeynaems JM, Robaye B, Kwak BR, Henrion D.

Arterioscler Thromb Vasc Biol. 2016 Aug;36(8):1598-606. doi: 10.1161/ATVBAHA.116.307739. Epub 2016 Jun 2.

30.

Comparison between direct and reverse electroporation of cells in situ: a simulation study.

Towhidi L, Khodadadi D, Maimari N, Pedrigi RM, Ip H, Kis Z, Kwak BR, Petrova TW, Delorenzi M, Krams R.

Physiol Rep. 2016 Mar;4(6). pii: e12673. doi: 10.14814/phy2.12673.

31.

Diabetes Mellitus Is Associated With Reduced High-Density Lipoprotein Sphingosine-1-Phosphate Content and Impaired High-Density Lipoprotein Cardiac Cell Protection.

Brinck JW, Thomas A, Lauer E, Jornayvaz FR, Brulhart-Meynet MC, Prost JC, Pataky Z, Löfgren P, Hoffstedt J, Eriksson M, Pramfalk C, Morel S, Kwak BR, van Eck M, James RW, Frias MA.

Arterioscler Thromb Vasc Biol. 2016 May;36(5):817-24. doi: 10.1161/ATVBAHA.115.307049. Epub 2016 Mar 10.

PMID:
26966278
32.

Sphingosine-1-phosphate reduces ischaemia-reperfusion injury by phosphorylating the gap junction protein Connexin43.

Morel S, Christoffersen C, Axelsen LN, Montecucco F, Rochemont V, Frias MA, Mach F, James RW, Naus CC, Chanson M, Lampe PD, Nielsen MS, Nielsen LB, Kwak BR.

Cardiovasc Res. 2016 Mar 1;109(3):385-96. doi: 10.1093/cvr/cvw004. Epub 2016 Jan 13.

33.

Atherosclerosis at arterial bifurcations: evidence for the role of haemodynamics and geometry.

Morbiducci U, Kok AM, Kwak BR, Stone PH, Steinman DA, Wentzel JJ.

Thromb Haemost. 2016 Mar;115(3):484-92. doi: 10.1160/TH15-07-0597. Epub 2016 Jan 7. Review.

PMID:
26740210
34.

Atherosclerosis severity is not affected by a deficiency in IL-33/ST2 signaling.

Martin P, Palmer G, Rodriguez E, Woldt E, Mean I, James RW, Smith DE, Kwak BR, Gabay C.

Immun Inflamm Dis. 2015 Sep;3(3):239-46. doi: 10.1002/iid3.62. Epub 2015 May 10.

35.

FOXC2 and fluid shear stress stabilize postnatal lymphatic vasculature.

Sabine A, Bovay E, Demir CS, Kimura W, Jaquet M, Agalarov Y, Zangger N, Scallan JP, Graber W, Gulpinar E, Kwak BR, Mäkinen T, Martinez-Corral I, Ortega S, Delorenzi M, Kiefer F, Davis MJ, Djonov V, Miura N, Petrova TV.

J Clin Invest. 2015 Oct 1;125(10):3861-77. doi: 10.1172/JCI80454. Epub 2015 Sep 21.

36.

Shear stress-induced atherosclerotic plaque composition in ApoE(-/-) mice is modulated by connexin37.

Pfenniger A, Meens MJ, Pedrigi RM, Foglia B, Sutter E, Pelli G, Rochemont V, Petrova TV, Krams R, Kwak BR.

Atherosclerosis. 2015 Nov;243(1):1-10. doi: 10.1016/j.atherosclerosis.2015.08.029. Epub 2015 Aug 25.

PMID:
26342936
37.

Endothelial Connexin37 and Connexin40 participate in basal but not agonist-induced NO release.

Meens MJ, Alonso F, Le Gal L, Kwak BR, Haefliger JA.

Cell Commun Signal. 2015 Jul 22;13:34. doi: 10.1186/s12964-015-0110-1.

38.

Role of connexins and pannexins in cardiovascular physiology.

Meens MJ, Kwak BR, Duffy HS.

Cell Mol Life Sci. 2015 Aug;72(15):2779-92. doi: 10.1007/s00018-015-1959-2. Epub 2015 Jun 20. Review.

PMID:
26091747
39.

Novel methodologies for biomarker discovery in atherosclerosis.

Hoefer IE, Steffens S, Ala-Korpela M, Bäck M, Badimon L, Bochaton-Piallat ML, Boulanger CM, Caligiuri G, Dimmeler S, Egido J, Evans PC, Guzik T, Kwak BR, Landmesser U, Mayr M, Monaco C, Pasterkamp G, Tuñón J, Weber C; ESC Working Group Atherosclerosis and Vascular Biology.

Eur Heart J. 2015 Oct 14;36(39):2635-42. doi: 10.1093/eurheartj/ehv236. Epub 2015 Jun 5. Review.

PMID:
26049157
40.

Functional role of a polymorphism in the Pannexin1 gene in collagen-induced platelet aggregation.

Molica F, Morel S, Meens MJ, Denis JF, Bradfield PF, Penuela S, Zufferey A, Monyer H, Imhof BA, Chanson M, Laird DW, Fontana P, Kwak BR.

Thromb Haemost. 2015 Aug;114(2):325-36. doi: 10.1160/TH14-11-0981. Epub 2015 May 7.

PMID:
25947940
41.

Erratum to "Adipokines at the crossroad between obesity and cardiovascular disease" (Thromb Haemost 2015; 113: 553-566).

Molica F, Morel S, Kwak BR, Rohner-Jeanrenaud F, Steffens S.

Thromb Haemost. 2015 Apr;113(4):909. doi: 10.1160/TH15040001. No abstract available.

PMID:
25822650
42.

Lymphatic vessels: an emerging actor in atherosclerotic plaque development.

Kutkut I, Meens MJ, McKee TA, Bochaton-Piallat ML, Kwak BR.

Eur J Clin Invest. 2015 Jan;45(1):100-8. doi: 10.1111/eci.12372. Review.

PMID:
25388153
43.

Adipokines at the crossroad between obesity and cardiovascular disease.

Molica F, Morel S, Kwak BR, Rohner-Jeanrenaud F, Steffens S.

Thromb Haemost. 2015 Mar;113(3):553-66. doi: 10.1160/TH14-06-0513. Epub 2014 Oct 23. Review. Erratum in: Thromb Haemost. 2015 Apr;113(4):909.

PMID:
25338625
44.

Biomechanical factors in atherosclerosis: mechanisms and clinical implications.

Kwak BR, Bäck M, Bochaton-Piallat ML, Caligiuri G, Daemen MJ, Davies PF, Hoefer IE, Holvoet P, Jo H, Krams R, Lehoux S, Monaco C, Steffens S, Virmani R, Weber C, Wentzel JJ, Evans PC.

Eur Heart J. 2014 Nov 14;35(43):3013-20, 3020a-3020d. doi: 10.1093/eurheartj/ehu353. Epub 2014 Sep 17.

45.

Mutations in cardiovascular connexin genes.

Molica F, Meens MJ, Morel S, Kwak BR.

Biol Cell. 2014 Sep;106(9):269-93. doi: 10.1111/boc.201400038. Epub 2014 Jul 24. Review.

PMID:
24966059
46.

Titration of the gap junction protein Connexin43 reduces atherogenesis.

Morel S, Chanson M, Nguyen TD, Glass AM, Richani Sarieddine MZ, Meens MJ, Burnier L, Kwak BR, Taffet SM.

Thromb Haemost. 2014 Aug;112(2):390-401. doi: 10.1160/TH13-09-0773. Epub 2014 May 15.

PMID:
24828015
47.

In vivo mapping of vascular inflammation using the translocator protein tracer 18F-FEDAA1106.

Cuhlmann S, Gsell W, Van der Heiden K, Habib J, Tremoleda JL, Khalil M, Turkheimer F, Meens MJ, Kwak BR, Bird J, Davenport AP, Clark J, Haskard D, Krams R, Jones H, Evans PC.

Mol Imaging. 2014;13. doi: 10.2310/7290.2014.00014.

PMID:
24825602
48.

Endothelial Cx40 limits myocardial ischaemia/reperfusion injury in mice.

Morel S, Braunersreuther V, Chanson M, Bouis D, Rochemont V, Foglia B, Pelli G, Sutter E, Pinsky DJ, Mach F, Kwak BR.

Cardiovasc Res. 2014 May 1;102(2):329-37. doi: 10.1093/cvr/cvu063. Epub 2014 Mar 17.

PMID:
24639196
49.

Cx26 regulates proliferation of repairing basal airway epithelial cells.

Crespin S, Bacchetta M, Bou Saab J, Tantilipikorn P, Bellec J, Dudez T, Nguyen TH, Kwak BR, Lacroix JS, Huang S, Wiszniewski L, Chanson M.

Int J Biochem Cell Biol. 2014 Jul;52:152-60. doi: 10.1016/j.biocel.2014.02.010. Epub 2014 Feb 22.

PMID:
24569117
50.

Connexins in lymphatic vessel physiology and disease.

Meens MJ, Sabine A, Petrova TV, Kwak BR.

FEBS Lett. 2014 Apr 17;588(8):1271-7. doi: 10.1016/j.febslet.2014.01.011. Epub 2014 Jan 20. Review.

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