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Items: 1 to 50 of 285

1.

Ultra-high-dose methylcobalamin in amyotrophic lateral sclerosis: a long-term phase II/III randomised controlled study.

Kaji R, Imai T, Iwasaki Y, Okamoto K, Nakagawa M, Ohashi Y, Takase T, Hanada T, Shimizu H, Tashiro K, Kuzuhara S.

J Neurol Neurosurg Psychiatry. 2019 Apr;90(4):451-457. doi: 10.1136/jnnp-2018-319294. Epub 2019 Jan 13.

2.

Nitrative Stress and Tau Accumulation in Amyotrophic Lateral Sclerosis/Parkinsonism-Dementia Complex (ALS/PDC) in the Kii Peninsula, Japan.

Hata Y, Ma N, Yoneda M, Morimoto S, Okano H, Murayama S, Kawanishi S, Kuzuhara S, Kokubo Y.

Front Neurosci. 2018 Jan 22;11:751. doi: 10.3389/fnins.2017.00751. eCollection 2017.

3.

Amyotrophic lateral sclerosis and parkinsonism-dementia complex of the Hohara focus of the Kii Peninsula: A multiple proteinopathy?

Mimuro M, Yoshida M, Kuzuhara S, Kokubo Y.

Neuropathology. 2018 Feb;38(1):98-107. doi: 10.1111/neup.12434. Epub 2017 Oct 23.

PMID:
29063640
4.

Optineurin pathology in the spinal cord of amyotrophic lateral sclerosis/parkinsonism-dementia complex patients in Kii Peninsula, Japan.

Morimoto S, Hatsuta H, Motoyama R, Kokubo Y, Ishiura H, Tsuji S, Kuzuhara S, Murayama S.

Brain Pathol. 2018 May;28(3):422-426. doi: 10.1111/bpa.12558. No abstract available.

PMID:
28960710
5.

A migration case of Kii amyotrophic lateral sclerosis/parkinsonism dementia complex with the shortest stay in the endemic area and the longest incubation to develop the disease.

Tsunoda K, Yamashita T, Shimada H, Nomura E, Takahashi Y, Shang J, Sato K, Takemoto M, Hishikawa N, Ohta Y, Higuchi M, Suhara T, Kokubo Y, Kuzuhara S, Abe K.

J Clin Neurosci. 2017 Dec;46:64-67. doi: 10.1016/j.jocn.2017.08.057. Epub 2017 Sep 7.

PMID:
28890043
6.

β-N-methylamino-l-alanine analysis in the brains of patients with Kii ALS/PDC.

Kokubo Y, Banack SA, Morimoto S, Murayama S, Togashi T, Metcalf JS, Cox PA, Kuzuhara S.

Neurology. 2017 Sep 5;89(10):1091-1092. doi: 10.1212/WNL.0000000000004310. Epub 2017 Aug 9. No abstract available.

PMID:
28794246
7.

The Improvement of the Outcome of Osmotic Demyelination Syndrome by Plasma Exchange.

Kumon S, Usui R, Kuzuhara S, Nitta K, Koike M.

Intern Med. 2017;56(6):733-736. doi: 10.2169/internalmedicine.56.7491. Epub 2017 Mar 17.

8.

Unusual tau pathology of the cerebellum in patients with amyotrophic lateral sclerosis/parkinsonism-dementia complex from the Kii Peninsula, Japan.

Morimoto S, Hatsuta H, Kokubo Y, Nakano Y, Hasegawa M, Yoneda M, Hirokawa Y, Kuzuhara S, Shiraishi T, Murayama S.

Brain Pathol. 2018 Mar;28(2):287-291. doi: 10.1111/bpa.12500. No abstract available.

PMID:
28236345
9.

CHCHD2 mutations in autosomal dominant late-onset Parkinson's disease: a genome-wide linkage and sequencing study.

Funayama M, Ohe K, Amo T, Furuya N, Yamaguchi J, Saiki S, Li Y, Ogaki K, Ando M, Yoshino H, Tomiyama H, Nishioka K, Hasegawa K, Saiki H, Satake W, Mogushi K, Sasaki R, Kokubo Y, Kuzuhara S, Toda T, Mizuno Y, Uchiyama Y, Ohno K, Hattori N.

Lancet Neurol. 2015 Mar;14(3):274-82. doi: 10.1016/S1474-4422(14)70266-2. Epub 2015 Feb 4.

PMID:
25662902
10.

Neutron activation analysis of scalp hair from ALS patients and residents in the Kii Peninsula, Japan.

Kihira T, Sakurai I, Yoshida S, Wakayama I, Takamiya K, Okumura R, Iinuma Y, Iwai K, Kajimoto Y, Hiwatani Y, Kohmoto J, Okamoto K, Kokubo Y, Kuzuhara S.

Biol Trace Elem Res. 2015 Mar;164(1):36-42. doi: 10.1007/s12011-014-0202-6. Epub 2014 Dec 20.

PMID:
25524522
11.

[Robert Wartenberg: the neurologist, the teacher, and the man].

Kuzuhara S.

Brain Nerve. 2014 Nov;66(11):1301-8. doi: 10.11477/mf.1416200032. Japanese.

PMID:
25407064
12.

Neuropsychological study of amyotrophic lateral sclerosis and parkinsonism-dementia complex in Kii peninsula, Japan.

Shindo A, Ueda Y, Kuzuhara S, Kokubo Y.

BMC Neurol. 2014 Jul 21;14:151. doi: 10.1186/1471-2377-14-151.

13.

Amyotrophic lateral sclerosis and parkinsonism in Papua, Indonesia: 2001-2012 survey results.

Okumiya K, Wada T, Fujisawa M, Ishine M, Garcia Del Saz E, Hirata Y, Kuzuhara S, Kokubo Y, Seguchi H, Sakamoto R, Manuaba I, Watofa P, Rantetampang AL, Matsubayashi K.

BMJ Open. 2014 Apr 16;4(4):e004353. doi: 10.1136/bmjopen-2013-004353.

14.

EIF4G1 gene mutations are not a common cause of Parkinson's disease in the Japanese population.

Nishioka K, Funayama M, Vilariño-Güell C, Ogaki K, Li Y, Sasaki R, Kokubo Y, Kuzuhara S, Kachergus JM, Cobb SA, Takahashi H, Mizuno Y, Farrer MJ, Ross OA, Hattori N.

Parkinsonism Relat Disord. 2014 Jun;20(6):659-61. doi: 10.1016/j.parkreldis.2014.03.004. Epub 2014 Mar 18.

15.
16.

Environmental characteristics and oxidative stress of inhabitants and patients with amyotrophic lateral sclerosis in a high-incidence area on the Kii Peninsula, Japan.

Kihira T, Okamoto K, Yoshida S, Kondo T, Iwai K, Wada S, Kajimoto Y, Kondo T, Kokubo Y, Kuzuhara S.

Intern Med. 2013;52(13):1479-86. Epub 2013 Jul 1.

17.

[Effects of using audiovisual materials in gerontological nursing exercises].

Kuzuhara S, Muroya K, Nomoto Y.

J UOEH. 2013 Jun 1;35(2):173-82. Japanese.

18.

Cerebrospinal Fluid Biomarkers for Kii Amyotrophic Lateral Sclerosis/Parkinsonism-Dementia Complex.

Nakayama Y, Morimoto S, Yoneda M, Kuzuhara S, Kokubo Y.

J Neurodegener Dis. 2013;2013:679089. doi: 10.1155/2013/679089. Epub 2013 Mar 27.

19.

Global aphasia without hemiparesis: the underlying mechanism examined by transcranial magnetic stimulation.

Shindo A, Satoh M, Naito Y, Asahi M, Takashima S, Sasaki R, Furukawa K, Narita Y, Kuzuhara S, Tomimoto H.

Neurologist. 2013 Jan;19(1):11-4. doi: 10.1097/NRL.0b013e31827c6b95.

PMID:
23269100
20.

Clinical features and a mutation with late onset of limb girdle muscular dystrophy 2B.

Takahashi T, Aoki M, Suzuki N, Tateyama M, Yaginuma C, Sato H, Hayasaka M, Sugawara H, Ito M, Abe-Kondo E, Shimakura N, Ibi T, Kuru S, Wakayama T, Sobue G, Fujii N, Saito T, Matsumura T, Funakawa I, Mukai E, Kawanami T, Morita M, Yamazaki M, Hasegawa T, Shimizu J, Tsuji S, Kuzuhara S, Tanaka H, Yoshioka M, Konno H, Onodera H, Itoyama Y.

J Neurol Neurosurg Psychiatry. 2013 Apr;84(4):433-40. doi: 10.1136/jnnp-2011-301339. Epub 2012 Dec 15.

21.

VPS35 mutation in Japanese patients with typical Parkinson's disease.

Ando M, Funayama M, Li Y, Kashihara K, Murakami Y, Ishizu N, Toyoda C, Noguchi K, Hashimoto T, Nakano N, Sasaki R, Kokubo Y, Kuzuhara S, Ogaki K, Yamashita C, Yoshino H, Hatano T, Tomiyama H, Hattori N.

Mov Disord. 2012 Sep 15;27(11):1413-7. doi: 10.1002/mds.25145. Epub 2012 Sep 18.

PMID:
22991136
22.

Analyses of the MAPT, PGRN, and C9orf72 mutations in Japanese patients with FTLD, PSP, and CBS.

Ogaki K, Li Y, Takanashi M, Ishikawa K, Kobayashi T, Nonaka T, Hasegawa M, Kishi M, Yoshino H, Funayama M, Tsukamoto T, Shioya K, Yokochi M, Imai H, Sasaki R, Kokubo Y, Kuzuhara S, Motoi Y, Tomiyama H, Hattori N.

Parkinsonism Relat Disord. 2013 Jan;19(1):15-20. doi: 10.1016/j.parkreldis.2012.06.019. Epub 2012 Jul 18.

PMID:
22818528
23.

[Parkinsonism-ALS-dementia complex of Guam and Kii peninsula].

Kuzuhara S.

Nihon Rinsho. 2011 Dec;69 Suppl 10 Pt 2:455-60. Japanese. No abstract available.

PMID:
22755234
24.

[Vascular parkinsonism].

Kuzuhara S.

Nihon Rinsho. 2011 Dec;69 Suppl 10 Pt 2:335-8. Review. Japanese. No abstract available.

PMID:
22755209
25.

α-Synuclein pathology in the amyotrophic lateral sclerosis/parkinsonism dementia complex in the Kii Peninsula, Japan.

Kokubo Y, Taniguchi A, Hasegawa M, Hayakawa Y, Morimoto S, Yoneda M, Hirokawa Y, Shiraishi T, Saito Y, Murayama S, Kuzuhara S.

J Neuropathol Exp Neurol. 2012 Jul;71(7):625-30. doi: 10.1097/NEN.0b013e31825b9680.

PMID:
22710962
26.

Mutational analysis of familial and sporadic amyotrophic lateral sclerosis with OPTN mutations in Japanese population.

Naruse H, Takahashi Y, Kihira T, Yoshida S, Kokubo Y, Kuzuhara S, Ishiura H, Amagasa M, Murayama S, Tsuji S, Goto J.

Amyotroph Lateral Scler. 2012 Oct;13(6):562-6. doi: 10.3109/17482968.2012.684213. Epub 2012 Jun 18.

PMID:
22708870
27.

C9ORF72 repeat expansion in amyotrophic lateral sclerosis in the Kii peninsula of Japan.

Ishiura H, Takahashi Y, Mitsui J, Yoshida S, Kihira T, Kokubo Y, Kuzuhara S, Ranum LP, Tamaoki T, Ichikawa Y, Date H, Goto J, Tsuji S.

Arch Neurol. 2012 Sep;69(9):1154-8. doi: 10.1001/archneurol.2012.1219.

PMID:
22637429
28.

An increase in ALS incidence on the Kii Peninsula, 1960-2009: a possible link to change in drinking water source.

Kihira T, Yoshida S, Kondo T, Iwai K, Wada S, Morinaga S, Kazimoto Y, Kondo T, Okamoto K, Kokubo Y, Kuzuhara S.

Amyotroph Lateral Scler. 2012 Jun;13(4):347-50. doi: 10.3109/17482968.2012.674140.

29.

ALS-parkinsonism-dementia complex of Kii and other related diseases in Japan.

Kaji R, Izumi Y, Adachi Y, Kuzuhara S.

Parkinsonism Relat Disord. 2012 Jan;18 Suppl 1:S190-1. doi: 10.1016/S1353-8020(11)70059-1. Review.

PMID:
22166431
30.

Cardiac ¹²³I-meta-iodobenzylguanidine scintigraphy in patients with amyotrophic lateral sclerosis and parkinsonism-dementia complex of the Kii peninsula, Japan.

Kokubo Y, Nomura Y, Morimoto S, Kuzuhara S.

Parkinsonism Relat Disord. 2012 Mar;18(3):306-8. doi: 10.1016/j.parkreldis.2011.08.005. Epub 2011 Aug 31. No abstract available.

PMID:
21885322
31.

Cardiac ¹²³I-meta-iodobenzylguanidine scintigraphy and lewy body pathology in a patient with amyotrophic lateral sclerosis and parkinsonism-dementia complex of Kii, Japan.

Kokubo Y, Morimoto S, Shindo A, Hirokawa Y, Shiraishi T, Saito Y, Murayama S, Kuzuhara S.

Mov Disord. 2011 Oct;26(12):2300-1. doi: 10.1002/mds.23850. Epub 2011 Jul 20. No abstract available.

PMID:
21780178
32.

PLA2G6 variant in Parkinson's disease.

Tomiyama H, Yoshino H, Ogaki K, Li L, Yamashita C, Li Y, Funayama M, Sasaki R, Kokubo Y, Kuzuhara S, Hattori N.

J Hum Genet. 2011 May;56(5):401-3. doi: 10.1038/jhg.2011.22. Epub 2011 Mar 3.

PMID:
21368765
33.

[Muro disease: amyotrophic lateral sclerosis/parkinsonism-dementia complex in Kii peninsula of Japan].

Kuzuhara S.

Brain Nerve. 2011 Feb;63(2):119-29. Review. Japanese.

PMID:
21301036
34.

Case of singing seizure using syllable names.

Shindo A, Satoh M, Ii Y, Kuzuhara S.

Neurologist. 2011 Jan;17(1):28-30. doi: 10.1097/NRL.0b013e3181fa13fb.

PMID:
21192189
35.

Prospective 10-year surveillance of human prion diseases in Japan.

Nozaki I, Hamaguchi T, Sanjo N, Noguchi-Shinohara M, Sakai K, Nakamura Y, Sato T, Kitamoto T, Mizusawa H, Moriwaka F, Shiga Y, Kuroiwa Y, Nishizawa M, Kuzuhara S, Inuzuka T, Takeda M, Kuroda S, Abe K, Murai H, Murayama S, Tateishi J, Takumi I, Shirabe S, Harada M, Sadakane A, Yamada M.

Brain. 2010 Oct;133(10):3043-57. doi: 10.1093/brain/awq216. Epub 2010 Sep 20.

PMID:
20855418
36.

[Treatment strategy of Alzheimer's disease: pause in clinical trials of Abeta vaccine and next steps].

Kuzuhara S.

Brain Nerve. 2010 Jul;62(7):659-66. Review. Japanese.

PMID:
20675870
37.

No evidence for pathogenic role of GIGYF2 mutation in Parkinson disease in Japanese patients.

Li L, Funayama M, Tomiyama H, Li Y, Yoshino H, Sasaki R, Kokubo Y, Kuzuhara S, Mizuno Y, Hattori N.

Neurosci Lett. 2010 Aug 2;479(3):245-8.

PMID:
20641165
38.

Clinical features of non-hypertensive lobar intracerebral hemorrhage related to cerebral amyloid angiopathy.

Hirohata M, Yoshita M, Ishida C, Ikeda SI, Tamaoka A, Kuzuhara S, Shoji M, Ando Y, Tokuda T, Yamada M.

Eur J Neurol. 2010 Jun 1;17(6):823-9. doi: 10.1111/j.1468-1331.2009.02940.x. Epub 2010 Feb 11.

PMID:
20158508
39.

[Changes in the incidence and clinical features of ALS in the Koza, Kozagawa, and Kushimoto area of the Kii Peninsula--from the 1960s to the 2000s (follow-up study)].

Kihira T, Yoshida S, Murata K, Ishiguti H, Kondo T, Kohmoto J, Okamoto K, Kokubo Y, Kuzuhara S.

Brain Nerve. 2010 Jan;62(1):72-80. Japanese.

PMID:
20112794
40.

[History of neurology and education on neurology in Japan].

Kuzuhara S.

Rinsho Shinkeigaku. 2009 Nov;49(11):968-71. Japanese.

PMID:
20030263
41.
42.

Painful neck on rotation: diagnostic significance for crowned dens syndrome.

Taniguchi A, Ogita K, Murata T, Kuzuhara S, Tomimoto H.

J Neurol. 2010 Jan;257(1):132-5. doi: 10.1007/s00415-009-5304-2.

PMID:
19727898
43.

17th Symposium on the Treatment of Parkinson's Disease. September 27, 2008, Tokyo. Foreword.

Kuzuhara S, Takahashi R.

J Neurol. 2009 Aug;256 Suppl 3:269. doi: 10.1007/s00415-009-5250-z. No abstract available.

PMID:
19711115
44.

Juvenile muscular atrophy of the distal upper extremity (hirayama disease) in two lanky look-alike brothers.

Kajikawa H, Kokubo Y, Taniguchi A, Naito Y, Kuzuhara S.

Neurologist. 2009 Jul;15(4):220-2. doi: 10.1097/NRL.0b013e3181942880.

PMID:
19590383
45.

Nationwide survey of acute juvenile female non-herpetic encephalitis in Japan: relationship to anti-N-methyl-D-aspartate receptor encephalitis.

Kamei S, Kuzuhara S, Ishihara M, Morita A, Taira N, Togo M, Matsui M, Ogawa M, Hisanaga K, Mizutani T, Kuno S.

Intern Med. 2009;48(9):673-9. Epub 2009 May 1.

46.

TRPM7 is not associated with amyotrophic lateral sclerosis-parkinsonism dementia complex in the Kii peninsula of Japan.

Hara K, Kokubo Y, Ishiura H, Fukuda Y, Miyashita A, Kuwano R, Sasaki R, Goto J, Nishizawa M, Kuzuhara S, Tsuji S.

Am J Med Genet B Neuropsychiatr Genet. 2010 Jan 5;153B(1):310-3. doi: 10.1002/ajmg.b.30966.

PMID:
19405049
47.

Agraphia in intellectually normal Japanese patients with ALS: omission of kana letters.

Satoh M, Takeda K, Kuzuhara S.

J Neurol. 2009 Sep;256(9):1455-60. doi: 10.1007/s00415-009-5136-0. Epub 2009 Apr 18.

PMID:
19377859
48.

[Treatment of Parkinson's disease at present and in the future].

Kuzuhara S.

Rinsho Shinkeigaku. 2008 Nov;48(11):835-43. Review. Japanese.

PMID:
19198095
49.

Interexaminer variance of median nerve compound muscle action potential measurements in hand position with and without fixation in plaster.

Higuchi K, Narita Y, Kuzuhara S.

J Clin Neuromuscul Dis. 2008 Dec;10(2):37-41. doi: 10.1097/CND.0b013e31818aab73.

PMID:
19169088
50.

Neuro-Sweet disease: report of the first autopsy case.

Kokubo Y, Kuzuhara S, Isoda K, Sato K, Kawada N, Narita Y.

BMJ Case Rep. 2009;2009. pii: bcr07.2008.0534. doi: 10.1136/bcr.07.2008.0534. Epub 2009 Jan 23.

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