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Items: 12


Regulation of the unfolded protein response through ATF4 and FAM129A in prostate cancer.

Pällmann N, Livgård M, Tesikova M, Zeynep Nenseth H, Akkus E, Sikkeland J, Jin Y, Koc D, Kuzu OF, Pradhan M, Danielsen HE, Kahraman N, Mokhlis HM, Ozpolat B, Banerjee PP, Uren A, Fazli L, Rennie PS, Jin Y, Saatcioglu F.

Oncogene. 2019 Aug;38(35):6301-6318. doi: 10.1038/s41388-019-0879-2. Epub 2019 Jul 16.


IRE1α-XBP1s pathway promotes prostate cancer by activating c-MYC signaling.

Sheng X, Nenseth HZ, Qu S, Kuzu OF, Frahnow T, Simon L, Greene S, Zeng Q, Fazli L, Rennie PS, Mills IG, Danielsen H, Theis F, Patterson JB, Jin Y, Saatcioglu F.

Nat Commun. 2019 Jan 24;10(1):323. doi: 10.1038/s41467-018-08152-3.


Identification of WEE1 as a target to make AKT inhibition more effective in melanoma.

Kuzu OF, Gowda R, Sharma A, Noory MA, Kardos G, Madhunapantula SV, Drabick JJ, Robertson GP.

Cancer Biol Ther. 2018 Jan 2;19(1):53-62. doi: 10.1080/15384047.2017.1360446. Epub 2017 Nov 30.


Improving pharmacological targeting of AKT in melanoma.

Kuzu OF, Gowda R, Sharma A, Noory MA, Dinavahi SS, Kardos G, Drabick JJ, Robertson GP.

Cancer Lett. 2017 Sep 28;404:29-36. doi: 10.1016/j.canlet.2017.07.001. Epub 2017 Jul 11.


Modulating cancer cell survival by targeting intracellular cholesterol transport.

Kuzu OF, Gowda R, Noory MA, Robertson GP.

Br J Cancer. 2017 Aug 8;117(4):513-524. doi: 10.1038/bjc.2017.200. Epub 2017 Jul 11.


Effect of lysosomotropic molecules on cellular homeostasis.

Kuzu OF, Toprak M, Noory MA, Robertson GP.

Pharmacol Res. 2017 Mar;117:177-184. doi: 10.1016/j.phrs.2016.12.021. Epub 2016 Dec 23. Review.


The Role of Cholesterol in Cancer.

Kuzu OF, Noory MA, Robertson GP.

Cancer Res. 2016 Apr 15;76(8):2063-70. doi: 10.1158/0008-5472.CAN-15-2613. Epub 2016 Apr 5. Review.


Current State of Animal (Mouse) Modeling in Melanoma Research.

Kuzu OF, Nguyen FD, Noory MA, Sharma A.

Cancer Growth Metastasis. 2015 Oct 6;8(Suppl 1):81-94. doi: 10.4137/CGM.S21214. eCollection 2015. Review.


A non-cytotoxic N-dehydroabietylamine derivative with potent antimalarial activity.

Sadashiva MP, Gowda R, Wu X, Inamdar GS, Kuzu OF, Rangappa KS, Robertson GP, Gowda DC.

Exp Parasitol. 2015 Aug;155:68-73. doi: 10.1016/j.exppara.2015.05.002. Epub 2015 May 14.


Nanolipolee-007, a novel nanoparticle-based drug containing leelamine for the treatment of melanoma.

Gowda R, Madhunapantula SV, Sharma A, Kuzu OF, Robertson GP.

Mol Cancer Ther. 2014 Oct;13(10):2328-40. doi: 10.1158/1535-7163.MCT-14-0357. Epub 2014 Jul 31.


Leelamine mediates cancer cell death through inhibition of intracellular cholesterol transport.

Kuzu OF, Gowda R, Sharma A, Robertson GP.

Mol Cancer Ther. 2014 Jul;13(7):1690-703. doi: 10.1158/1535-7163.MCT-13-0868. Epub 2014 Mar 31.


Targeting multiple key signaling pathways in melanoma using leelamine.

Gowda R, Madhunapantula SV, Kuzu OF, Sharma A, Robertson GP.

Mol Cancer Ther. 2014 Jul;13(7):1679-89. doi: 10.1158/1535-7163.MCT-13-0867. Epub 2014 Mar 31.

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