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Items: 1 to 50 of 51

1.

Primed CRISPR adaptation in Escherichia coli cells does not depend on conformational changes in the Cascade effector complex detected in Vitro.

Krivoy A, Rutkauskas M, Kuznedelov K, Musharova O, Rouillon C, Severinov K, Seidel R.

Nucleic Acids Res. 2018 May 4;46(8):4087-4098. doi: 10.1093/nar/gky219.

2.

Acinetodin and Klebsidin, RNA Polymerase Targeting Lasso Peptides Produced by Human Isolates of Acinetobacter gyllenbergii and Klebsiella pneumoniae.

Metelev M, Arseniev A, Bushin LB, Kuznedelov K, Artamonova TO, Kondratenko R, Khodorkovskii M, Seyedsayamdost MR, Severinov K.

ACS Chem Biol. 2017 Mar 17;12(3):814-824. doi: 10.1021/acschembio.6b01154. Epub 2017 Feb 3.

PMID:
28106375
3.

Altered stoichiometry Escherichia coli Cascade complexes with shortened CRISPR RNA spacers are capable of interference and primed adaptation.

Kuznedelov K, Mekler V, Lemak S, Tokmina-Lukaszewska M, Datsenko KA, Jain I, Savitskaya E, Mallon J, Shmakov S, Bothner B, Bailey S, Yakunin AF, Severinov K, Semenova E.

Nucleic Acids Res. 2016 Dec 15;44(22):10849-10861. Epub 2016 Oct 13.

4.

Kinetics of the CRISPR-Cas9 effector complex assembly and the role of 3'-terminal segment of guide RNA.

Mekler V, Minakhin L, Semenova E, Kuznedelov K, Severinov K.

Nucleic Acids Res. 2016 Apr 7;44(6):2837-45. doi: 10.1093/nar/gkw138. Epub 2016 Mar 3.

5.

New Infestin-4 Mutants with Increased Selectivity against Factor XIIa.

Kolyadko VN, Lushchekina SV, Vuimo TA, Surov SS, Ovsepyan RA, Korneeva VA, Vorobiev II, Orlova NA, Minakhin L, Kuznedelov K, Severinov KV, Ataullakhanov FI, Panteleev MA.

PLoS One. 2015 Dec 15;10(12):e0144940. doi: 10.1371/journal.pone.0144940. eCollection 2015.

6.

The Cas6e ribonuclease is not required for interference and adaptation by the E. coli type I-E CRISPR-Cas system.

Semenova E, Kuznedelov K, Datsenko KA, Boudry PM, Savitskaya EE, Medvedeva S, Beloglazova N, Logacheva M, Yakunin AF, Severinov K.

Nucleic Acids Res. 2015 Jul 13;43(12):6049-61. doi: 10.1093/nar/gkv546. Epub 2015 May 26.

7.

CRISPR RNA binding and DNA target recognition by purified Cascade complexes from Escherichia coli.

Beloglazova N, Kuznedelov K, Flick R, Datsenko KA, Brown G, Popovic A, Lemak S, Semenova E, Severinov K, Yakunin AF.

Nucleic Acids Res. 2015 Jan;43(1):530-43. doi: 10.1093/nar/gku1285. Epub 2014 Dec 8.

8.

The RimL transacetylase provides resistance to translation inhibitor microcin C.

Kazakov T, Kuznedelov K, Semenova E, Mukhamedyarov D, Datsenko KA, Metlitskaya A, Vondenhoff GH, Tikhonov A, Agarwal V, Nair S, Van Aerschot A, Severinov K.

J Bacteriol. 2014 Oct;196(19):3377-85. doi: 10.1128/JB.01584-14. Epub 2014 Jul 7.

9.

Analysis of the mechanism of nucleosome survival during transcription.

Chang HW, Kulaeva OI, Shaytan AK, Kibanov M, Kuznedelov K, Severinov KV, Kirpichnikov MP, Clark DJ, Studitsky VM.

Nucleic Acids Res. 2014 Feb;42(3):1619-27. doi: 10.1093/nar/gkt1120. Epub 2013 Nov 13.

10.

RNA polymerase-promoter interactions determining different stability of the Escherichia coli and Thermus aquaticus transcription initiation complexes.

Mekler V, Minakhin L, Kuznedelov K, Mukhamedyarov D, Severinov K.

Nucleic Acids Res. 2012 Dec;40(22):11352-62. doi: 10.1093/nar/gks973. Epub 2012 Oct 18.

11.

A novel phage-encoded transcription antiterminator acts by suppressing bacterial RNA polymerase pausing.

Berdygulova Z, Esyunina D, Miropolskaya N, Mukhamedyarov D, Kuznedelov K, Nickels BE, Severinov K, Kulbachinskiy A, Minakhin L.

Nucleic Acids Res. 2012 May;40(9):4052-63. doi: 10.1093/nar/gkr1285. Epub 2012 Jan 11.

12.

Francisella RNA polymerase contains a heterodimer of non-identical α subunits.

Mukhamedyarov D, Makarova KS, Severinov K, Kuznedelov K.

BMC Mol Biol. 2011 Nov 22;12:50. doi: 10.1186/1471-2199-12-50.

13.

Chemical synthesis enables biochemical and antibacterial evaluation of streptolydigin antibiotics.

Pronin SV, Martinez A, Kuznedelov K, Severinov K, Shuman HA, Kozmin SA.

J Am Chem Soc. 2011 Aug 10;133(31):12172-84. doi: 10.1021/ja2041964. Epub 2011 Jul 20.

14.

The antibacterial threaded-lasso peptide capistruin inhibits bacterial RNA polymerase.

Kuznedelov K, Semenova E, Knappe TA, Mukhamedyarov D, Srivastava A, Chatterjee S, Ebright RH, Marahiel MA, Severinov K.

J Mol Biol. 2011 Oct 7;412(5):842-8. doi: 10.1016/j.jmb.2011.02.060. Epub 2011 Mar 15.

15.

Synthetic microcin C analogs targeting different aminoacyl-tRNA synthetases.

Van de Vijver P, Vondenhoff GH, Kazakov TS, Semenova E, Kuznedelov K, Metlitskaya A, Van Aerschot A, Severinov K.

J Bacteriol. 2009 Oct;191(20):6273-80. doi: 10.1128/JB.00829-09. Epub 2009 Aug 14.

16.

Recombinant bacterial RNA polymerase: preparation and applications.

Kuznedelov K, Severinov K.

Methods. 2009 Jan;47(1):44-52. doi: 10.1016/j.ymeth.2008.10.007. Epub 2008 Oct 21.

PMID:
18948202
17.

Crystal structure of Escherichia coli Rnk, a new RNA polymerase-interacting protein.

Lamour V, Rutherford ST, Kuznedelov K, Ramagopal UA, Gourse RL, Severinov K, Darst SA.

J Mol Biol. 2008 Nov 7;383(2):367-79. doi: 10.1016/j.jmb.2008.08.011. Epub 2008 Aug 12.

18.

Structural modules of RNA polymerase required for transcription from promoters containing downstream basal promoter element GGGA.

Barinova N, Kuznedelov K, Severinov K, Kulbachinskiy A.

J Biol Chem. 2008 Aug 15;283(33):22482-9. doi: 10.1074/jbc.M802445200. Epub 2008 Jun 23.

19.

Rapid isolation and identification of bacteriophage T4-encoded modifications of Escherichia coli RNA polymerase: a generic method to study bacteriophage/host interactions.

Westblade LF, Minakhin L, Kuznedelov K, Tackett AJ, Chang EJ, Mooney RA, Vvedenskaya I, Wang QJ, Fenyö D, Rout MP, Landick R, Chait BT, Severinov K, Darst SA.

J Proteome Res. 2008 Mar;7(3):1244-50. doi: 10.1021/pr070451j. Epub 2008 Feb 14.

20.

The role of the bacterial RNA polymerase beta subunit flexible flap domain in transcription termination.

Kuznedelov KD, Komissarova NV, Severinov KV.

Dokl Biochem Biophys. 2006 Sep-Oct;410:263-6. No abstract available.

PMID:
17286098
21.

Temporal regulation of viral transcription during development of Thermus thermophilus bacteriophage phiYS40.

Sevostyanova A, Djordjevic M, Kuznedelov K, Naryshkina T, Gelfand MS, Severinov K, Minakhin L.

J Mol Biol. 2007 Feb 16;366(2):420-35. Epub 2006 Nov 18.

22.

A basal promoter element recognized by free RNA polymerase sigma subunit determines promoter recognition by RNA polymerase holoenzyme.

Feklistov A, Barinova N, Sevostyanova A, Heyduk E, Bass I, Vvedenskaya I, Kuznedelov K, Merkiene E, Stavrovskaya E, Klimasauskas S, Nikiforov V, Heyduk T, Severinov K, Kulbachinskiy A.

Mol Cell. 2006 Jul 7;23(1):97-107. Epub 2006 Jun 22.

23.

The role of the largest RNA polymerase subunit lid element in preventing the formation of extended RNA-DNA hybrid.

Naryshkina T, Kuznedelov K, Severinov K.

J Mol Biol. 2006 Aug 25;361(4):634-43. Epub 2006 Jun 5.

PMID:
16781733
24.

Recombinant Thermus aquaticus RNA polymerase for structural studies.

Kuznedelov K, Lamour V, Patikoglou G, Chlenov M, Darst SA, Severinov K.

J Mol Biol. 2006 May 26;359(1):110-21. Epub 2006 Mar 23.

PMID:
16618493
25.

A consensus adenine at position -11 of the nontemplate strand of bacterial promoter is important for nucleation of promoter melting.

Heyduk E, Kuznedelov K, Severinov K, Heyduk T.

J Biol Chem. 2006 May 5;281(18):12362-9. Epub 2006 Mar 9.

26.

The mechanism of DNA replication primer synthesis by RNA polymerase.

Zenkin N, Naryshkina T, Kuznedelov K, Severinov K.

Nature. 2006 Feb 2;439(7076):617-20.

PMID:
16452982
27.

Preparation and characterization of recombinant Thermus aquaticus RNA polymerase.

Kuznedelov K, Minakhin L, Severinov K.

Methods Enzymol. 2003;370:94-108. No abstract available.

PMID:
14712637
28.

Genome of Xanthomonas oryzae bacteriophage Xp10: an odd T-odd phage.

Yuzenkova J, Nechaev S, Berlin J, Rogulja D, Kuznedelov K, Inman R, Mushegian A, Severinov K.

J Mol Biol. 2003 Jul 18;330(4):735-48.

PMID:
12850143
29.

Interaction of T4 AsiA with its target sites in the RNA polymerase sigma70 subunit leads to distinct and opposite effects on transcription.

Minakhin L, Niedziela-Majka A, Kuznedelov K, Adelman K, Urbauer JL, Heyduk T, Severinov K.

J Mol Biol. 2003 Feb 21;326(3):679-90.

PMID:
12581632
30.

Multiple roles of the RNA polymerase beta subunit flap domain in sigma 54-dependent transcription.

Wigneshweraraj SR, Kuznedelov K, Severinov K, Buck M.

J Biol Chem. 2003 Jan 31;278(5):3455-65. Epub 2002 Nov 6.

33.

A role for interaction of the RNA polymerase flap domain with the sigma subunit in promoter recognition.

Kuznedelov K, Minakhin L, Niedziela-Majka A, Dove SL, Rogulja D, Nickels BE, Hochschild A, Heyduk T, Severinov K.

Science. 2002 Feb 1;295(5556):855-7.

34.

[Structure of scolex hooks and genosystematics of Triaenophorus nodulosus (Cestoda: pseudophyllidea) from the Baikal lake].

Rusinek OT, Kuznedelov KD.

Parazitologiia. 2001 Mar-Apr;35(2):98-104. Russian.

PMID:
11548588
35.
36.

The alpha subunit of E. coli RNA polymerase activates RNA binding by NusA.

Mah TF, Kuznedelov K, Mushegian A, Severinov K, Greenblatt J.

Genes Dev. 2000 Oct 15;14(20):2664-75.

38.
40.

[Species diversity of picoplankton from Lake Baikal by comparative analysis of 5'-terminal segments of 16S rRNA genes].

Semenova EA, Kuznedelov KD.

Mol Biol (Mosk). 1998 Sep-Oct;32(5):895-901. Russian. No abstract available.

PMID:
9914978
41.
42.
43.
44.

[Molecular phylogeny of Turbellaria, based on data from comparing the nucleotide sequences of 18S ribosomal RNA genes].

Kuznedelov KD, Timoshkin OA.

Mol Biol (Mosk). 1995 May-Jun;29(3):553-62. Russian.

PMID:
8552060
46.

Molecular cloning and sequencing of omul prolactin cDNA.

Trofimova IN, Kuznedelov KD, Kumarev VP, Golovin SY.

Mol Mar Biol Biotechnol. 1993 Feb;2(1):41-3.

PMID:
8364687
47.

Super-rapid synthesis of oligodeoxynucleotides on a micro-scale.

Kumarev VP, Kobzev VF, Kuznedelov KD, Sredin YuG.

Nucleic Acids Symp Ser. 1991;(24):234. No abstract available.

PMID:
1841306
48.

[Rapid automated synthesis of polydeoxynucleotides].

Kumarev VP, Baranova LV, Kobzev VF, Kuznedelov KD, Sredin IuG.

Bioorg Khim. 1988 Feb;14(2):276-8. Russian.

PMID:
3382438
49.

[Plasmid vector pSSC1 for cloning synthetic polynucleotides and their regeneration with a unique nucleotide sequence].

Kuznedelov KD, Kolocheva TI, Rivkin MI, Kumarev VP.

Bioorg Khim. 1986 Jun;12(6):842-4. Russian.

PMID:
3022755
50.

[Construction of expression vectors with strong promoters on the basis of plasmid pBR327].

Kuznedelov KD, Rivkin MI, Kumarev VP, Kravchenko VV.

Dokl Akad Nauk SSSR. 1986;286(4):1012-5. Russian. No abstract available.

PMID:
3004872

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