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Items: 1 to 50 of 98

1.

Use of hepatocytes isolated from a liver-humanized mouse for studies on the metabolism of drugs: application to the metabolism of fentanyl and acetylfentanyl.

Kanamori T, Togawa-Iwata Y, Segawa H, Yamamuro T, Kuwayama K, Tsujikawa K, Inoue H.

Forensic Toxicol. 2018;36(2):467-475. doi: 10.1007/s11419-018-0425-x. Epub 2018 Jun 4.

2.

Down-regulation of MDR1 by Ad-DKK3 via Akt/NFκB pathways augments the anti-tumor effect of temozolomide in glioblastoma cells and a murine xenograft model.

Fujihara T, Mizobuchi Y, Nakajima K, Kageji T, Matsuzaki K, Kitazato KT, Otsuka R, Hara K, Mure H, Okazaki T, Kuwayama K, Nagahiro S, Takagi Y.

J Neurooncol. 2018 May 19. doi: 10.1007/s11060-018-2894-5. [Epub ahead of print]

PMID:
29779087
3.

Micro-segmental hair analysis for proving drug-facilitated crimes: Evidence that a victim ingested a sleeping aid, diphenhydramine, on a specific day.

Kuwayama K, Nariai M, Miyaguchi H, Iwata YT, Kanamori T, Tsujikawa K, Yamamuro T, Segawa H, Abe H, Iwase H, Inoue H.

Forensic Sci Int. 2018 Jul;288:23-28. doi: 10.1016/j.forsciint.2018.04.027. Epub 2018 Apr 22.

PMID:
29705586
4.

Development of rapid and simple method for DNA extraction from cannabis resin based on the evaluation of relative PCR amplification ability.

Yamamuro T, Iwata YT, Segawa H, Kuwayama K, Tsujikawa K, Kanamori T, Inoue H.

Forensic Sci Int. 2018 Jun;287:176-182. doi: 10.1016/j.forsciint.2018.03.044. Epub 2018 Apr 4.

PMID:
29677592
5.

Treatment of Unruptured Cerebral Aneurysms with the Mineralocorticoid Receptor Blocker Eplerenone-Pilot Study.

Nagahiro S, Tada Y, Satomi J, Kinouchi T, Kuwayama K, Yagi K, Nakajima K, Matsushita N, Miyamoto T, Yamaguchi T, Shimada K, Korai M, Mure H, Okayama Y, Abe T, Harada M, Kitazato KT, Kanematsu Y.

J Stroke Cerebrovasc Dis. 2018 Aug;27(8):2134-2140. doi: 10.1016/j.jstrokecerebrovasdis.2018.03.008. Epub 2018 Apr 2.

6.

Metabolism of Fentanyl and Acetylfentanyl in Human-Induced Pluripotent Stem Cell-Derived Hepatocytes.

Kanamori T, Togawa Iwata Y, Segawa H, Yamamuro T, Kuwayama K, Tsujikawa K, Inoue H.

Biol Pharm Bull. 2018;41(1):106-114. doi: 10.1248/bpb.b17-00709.

7.

Comparison and evaluation of the quick purification methods of methamphetamine hydrochloride from dimethyl sulfone for spectroscopic identification.

Segawa H, Kumisaka K, Sugita R, Iwata YT, Yamamuro T, Kuwayama K, Tsujikawa K, Kanamori T, Inoue H.

Forensic Sci Int. 2018 Jan;282:86-91. doi: 10.1016/j.forsciint.2017.11.016. Epub 2017 Nov 21.

PMID:
29174515
8.
9.

Different localizations of drugs simultaneously administered in a strand of hair by micro-segmental analysis.

Kuwayama K, Miyaguchi H, Iwata YT, Kanamori T, Tsujikawa K, Yamamuro T, Segawa H, Inoue H.

Drug Test Anal. 2018 Apr;10(4):750-760. doi: 10.1002/dta.2259. Epub 2017 Oct 17.

PMID:
28809091
10.

Characterization and Differentiation of Geometric Isomers of 3-methylfentanyl Analogs by Gas Chromatography/Mass Spectrometry, Liquid Chromatography/Mass Spectrometry, and Nuclear Magnetic Resonance Spectroscopy.

Kanamori T, Iwata YT, Segawa H, Yamamuro T, Kuwayama K, Tsujikawa K, Inoue H.

J Forensic Sci. 2017 Nov;62(6):1472-1478. doi: 10.1111/1556-4029.13395. Epub 2017 Jun 26.

PMID:
28649754
11.

[Pulsatile Tinnitus due to an Aberrant Internal Carotid Artery in the Middle Ear:A Case Report].

Kuwayama K, Satomi J, Yamaguchi T, Yamaguchi I, Sogabe S, Yoshioka S, Nagahiro S.

No Shinkei Geka. 2017 Apr;45(4):321-324. doi: 10.11477/mf.1436203502. Japanese.

PMID:
28415056
12.

Intra-arterial high signals on arterial spin labeling perfusion images predict the occluded internal carotid artery segment.

Sogabe S, Satomi J, Tada Y, Kanematsu Y, Kuwayama K, Yagi K, Yoshioka S, Mizobuchi Y, Mure H, Yamaguchi I, Abe T, Yamamoto N, Kitazato KT, Kaji R, Harada M, Nagahiro S.

Neuroradiology. 2017 Jun;59(6):587-595. doi: 10.1007/s00234-017-1828-9. Epub 2017 Apr 10.

PMID:
28397019
13.

Treatment Outcome of Carotid Artery Stenting Underwent within 14 Days of Stroke Onset - Consideration of Safety and Efficacy of Urgent Carotid Artery Stenting for Neurologically Progressing Patients.

Kanematsu Y, Satomi J, Kuwayama K, Yamaguchi I, Yoshioka S, Kinouchi T, Tada Y, Yamamoto N, Matsubara S, Satoh K, Nagahiro S.

Neurol Med Chir (Tokyo). 2017 Jun 15;57(6):278-283. doi: 10.2176/nmc.oa.2016-0236. Epub 2017 Apr 6.

14.

Blocking COX-2 induces apoptosis and inhibits cell proliferation via the Akt/survivin- and Akt/ID3 pathway in low-grade-glioma.

Sato A, Mizobuchi Y, Nakajima K, Shono K, Fujihara T, Kageji T, Kitazato K, Matsuzaki K, Mure H, Kuwayama K, Sumi A, Saya H, Sampetrean O, Nagahirao S.

J Neurooncol. 2017 Apr;132(2):231-238. doi: 10.1007/s11060-017-2380-5. Epub 2017 Mar 10.

PMID:
28283800
15.

Enantioseparation of methamphetamine by supercritical fluid chromatography with cellulose-based packed column.

Segawa H, Iwata YT, Yamamuro T, Kuwayama K, Tsujikawa K, Kanamori T, Inoue H.

Forensic Sci Int. 2017 Apr;273:39-44. doi: 10.1016/j.forsciint.2017.01.025. Epub 2017 Feb 4.

PMID:
28213186
16.

Fructose suppresses uric acid excretion to the intestinal lumen as a result of the induction of oxidative stress by NADPH oxidase activation.

Kaneko C, Ogura J, Sasaki S, Okamoto K, Kobayashi M, Kuwayama K, Narumi K, Iseki K.

Biochim Biophys Acta. 2017 Mar;1861(3):559-566. doi: 10.1016/j.bbagen.2016.11.042. Epub 2016 Nov 30.

PMID:
27913188
17.

Synthesis and Analysis of Glucuronic Acid-Conjugated Metabolites of 4-Bromo-2,5-Dimethoxyphenethylamine.

Kanamori T, Yamamuro T, Kuwayama K, Tsujikawa K, Iwata YT, Inoue H.

J Forensic Sci. 2017 Mar;62(2):488-492. doi: 10.1111/1556-4029.13266. Epub 2016 Nov 22.

PMID:
27874182
18.

Three-step drug extraction from a single sub-millimeter segment of hair and nail to determine the exact day of drug intake.

Kuwayama K, Miyaguchi H, Iwata YT, Kanamori T, Tsujikawa K, Yamamuro T, Segawa H, Inoue H.

Anal Chim Acta. 2016 Dec 15;948:40-47. doi: 10.1016/j.aca.2016.10.029. Epub 2016 Oct 30.

PMID:
27871608
19.

Development of a new field-test procedure for cocaine.

Tsujikawa K, Iwata YT, Segawa H, Yamamuro T, Kuwayama K, Kanamori T, Inoue H.

Forensic Sci Int. 2017 Jan;270:267-274. doi: 10.1016/j.forsciint.2016.10.019. Epub 2016 Nov 1.

PMID:
27836413
20.

Approaching over 10 000-fold sensitivity increase in chiral capillary electrophoresis: Cation-selective exhaustive injection and sweeping cyclodextrin-modified micellar electrokinetic chromatography.

Mikuma T, Iwata YT, Miyaguchi H, Kuwayama K, Tsujikawa K, Kanamori T, Kanazawa H, Inoue H.

Electrophoresis. 2016 Nov;37(22):2970-2976. doi: 10.1002/elps.201600324. Epub 2016 Sep 7.

PMID:
27542560
21.

Development of a novel immunoassay for herbal cannabis using a new fluorescent antibody probe, "Ultra Quenchbody".

Tsujikawa K, Saiki F, Yamamuro T, Iwata YT, Abe R, Ohashi H, Kaigome R, Yamane K, Kuwayama K, Kanamori T, Inoue H.

Forensic Sci Int. 2016 Sep;266:541-548. doi: 10.1016/j.forsciint.2016.07.022. Epub 2016 Aug 2.

PMID:
27514015
22.

Differentiation of ring-substituted regioisomers of amphetamine and methamphetamine by supercritical fluid chromatography.

Segawa H, T Iwata Y, Yamamuro T, Kuwayama K, Tsujikawa K, Kanamori T, Inoue H.

Drug Test Anal. 2017 Mar;9(3):389-398. doi: 10.1002/dta.2040. Epub 2016 Aug 8.

PMID:
27383263
23.

Development of a Library Search-Based Screening System for 3,4-Methylenedioxymethamphetamine in Ecstasy Tablets Using a Portable Near-Infrared Spectrometer.

Tsujikawa K, Yamamuro T, Kuwayama K, Kanamori T, Iwata YT, Miyamoto K, Kasuya F, Inoue H.

J Forensic Sci. 2016 Sep;61(5):1208-14. doi: 10.1111/1556-4029.13122. Epub 2016 Jun 30.

PMID:
27362667
24.

Time-course measurements of drug concentrations in hair and toenails after single administrations of pharmaceutical products.

Kuwayama K, Miyaguchi H, Iwata YT, Kanamori T, Tsujikawa K, Yamamuro T, Segawa H, Inoue H.

Drug Test Anal. 2017 Apr;9(4):571-577. doi: 10.1002/dta.1991. Epub 2016 Jun 24.

PMID:
27341179
25.

Urinary Excretion Profiles of 2,5-Dimethoxy-4-alkylthiophenethylamine Analogs in Rats.

Kanamori T, Kuwayama K, Tsujikawa K, T Iwata Y, Inoue H.

Biol Pharm Bull. 2016;39(5):883-6. doi: 10.1248/bpb.b15-00953.

26.

Highly sensitive quantification of unconjugated 11-nor-9-carboxy-Δ(9)-tetrahydrocannabinol in a cannabis user's hair using micropulverized extraction.

Kuwayama K, Miyaguchi H, Yamamuro T, Tsujikawa K, Kanamori T, Iwata YT, Inoue H.

Forensic Sci Int. 2016 May;262:e34-6. doi: 10.1016/j.forsciint.2016.03.009. Epub 2016 Mar 16.

PMID:
27020617
27.

Differentiation of regioisomeric chloroamphetamine analogs using gas chromatography-chemical ionization-tandem mass spectrometry.

Negishi S, Nakazono Y, Iwata YT, Kanamori T, Tsujikawa K, Kuwayama K, Yamamuro T, Miyamoto K, Yamashita T, Kasuya F, Inoue H.

Forensic Toxicol. 2015;33(2):338-347. Epub 2015 May 19.

28.

Micro-pulverized extraction pretreatment for highly sensitive analysis of 11-nor-9-carboxy-Δ(9)-tetrahydrocannabinol in hair by liquid chromatography/tandem mass spectrometry.

Kuwayama K, Miyaguchi H, Yamamuro T, Tsujikawa K, Kanamori T, Iwata YT, Inoue H.

Rapid Commun Mass Spectrom. 2015 Nov 30;29(22):2158-66. doi: 10.1002/rcm.7363.

PMID:
26467228
29.

Reactive oxygen species derived from xanthine oxidase interrupt dimerization of breast cancer resistance protein, resulting in suppression of uric acid excretion to the intestinal lumen.

Ogura J, Kuwayama K, Sasaki S, Kaneko C, Koizumi T, Yabe K, Tsujimoto T, Takeno R, Takaya A, Kobayashi M, Yamaguchi H, Iseki K.

Biochem Pharmacol. 2015 Sep 1;97(1):89-98. doi: 10.1016/j.bcp.2015.06.021. Epub 2015 Jun 25.

PMID:
26119820
30.

Effectiveness of saliva and fingerprints as alternative specimens to urine and blood in forensic drug testing.

Kuwayama K, Miyaguchi H, Yamamuro T, Tsujikawa K, Kanamori T, Iwata YT, Inoue H.

Drug Test Anal. 2016 Jul;8(7):644-51. doi: 10.1002/dta.1831. Epub 2015 Jun 15.

PMID:
26074137
31.

The accumulation of brain water-free sodium is associated with ischemic damage independent of the blood pressure in female rats.

Sumiyoshi M, Kitazato KT, Yagi K, Miyamoto T, Kurashiki Y, Matsushita N, Kinouchi T, Kuwayama K, Satomi J, Nagahiro S.

Brain Res. 2015 Aug 7;1616:37-44. doi: 10.1016/j.brainres.2015.04.051. Epub 2015 May 7.

32.

PPARγ-Dependent and -Independent Inhibition of the HMGB1/TLR9 Pathway by Eicosapentaenoic Acid Attenuates Ischemic Brain Damage in Ovariectomized Rats.

Sumiyoshi M, Satomi J, Kitazato KT, Yagi K, Shimada K, Kurashiki Y, Korai M, Miyamoto T, Suzue R, Kuwayama K, Nagahiro S.

J Stroke Cerebrovasc Dis. 2015 Jun;24(6):1187-95. doi: 10.1016/j.jstrokecerebrovasdis.2015.01.009. Epub 2015 Apr 25.

33.

Improvement of Plasma Biomarkers after Switching Stroke Patients from Other Angiotensin II Type I Receptor Blockers to Olmesartan.

Tada Y, Yagi K, Uno M, Matsushita N, Kanematsu Y, Kuwayama K, Shimada K, Nishi K, Hirasawa M, Satomi J, Kitazato KT, Kageji T, Matsuura E, Nagahiro S.

J Stroke Cerebrovasc Dis. 2015 Jul;24(7):1487-92. doi: 10.1016/j.jstrokecerebrovasdis.2015.03.015. Epub 2015 Apr 16.

34.

Transarterial N-Butyl-2-cyanoacrylate Embolization of an Intraosseous Dural Arteriovenous Fistula Associated With Acute Epidural Hematoma: Technical Case Report.

Yoshioka S, Kuwayama K, Satomi J, Nagahiro S.

Neurosurgery. 2015 Sep;11 Suppl 3:E468-71. doi: 10.1227/NEU.0000000000000773.

PMID:
25875581
35.

The use of a sulfonated capillary on chiral capillary electrophoresis/mass spectrometry of amphetamine-type stimulants for methamphetamine impurity profiling.

Mikuma T, Iwata YT, Miyaguchi H, Kuwayama K, Tsujikawa K, Kanamori T, Inoue H.

Forensic Sci Int. 2015 Apr;249:59-65. doi: 10.1016/j.forsciint.2015.01.015. Epub 2015 Jan 30.

PMID:
25679984
36.

Detection of main metabolites of XLR-11 and its thermal degradation product in human hepatoma HepaRG cells and human urine.

Kanamori T, Kanda K, Yamamuro T, Kuwayama K, Tsujikawa K, Iwata YT, Inoue H.

Drug Test Anal. 2015 Apr;7(4):341-5. doi: 10.1002/dta.1765. Epub 2015 Jan 19.

PMID:
25600155
37.

Instability of the hydrochloride salts of cathinone derivatives in air.

Tsujikawa K, Yamamuro T, Kuwayama K, Kanamori T, Iwata YT, Inoue H.

Forensic Sci Int. 2015 Mar;248:48-54. doi: 10.1016/j.forsciint.2014.12.016. Epub 2014 Dec 25.

PMID:
25594691
38.

Blocking of the interaction between Wnt proteins and their co-receptors contributes to the anti-tumor effects of adenovirus-mediated DKK3 in glioblastoma.

Hara K, Kageji T, Mizobuchi Y, Kitazato KT, Okazaki T, Fujihara T, Nakajima K, Mure H, Kuwayama K, Hara T, Nagahiro S.

Cancer Lett. 2015 Jan 28;356(2 Pt B):496-505. doi: 10.1016/j.canlet.2014.09.045. Epub 2014 Oct 6.

PMID:
25301448
39.

Intra-arterial signal on arterial spin labeling perfusion MRI to identify the presence of acute middle cerebral artery occlusion.

Tada Y, Satomi J, Abe T, Kuwayama K, Sogabe S, Fujita K, Yamamoto N, Kaji R, Harada M, Nagahiro S.

Cerebrovasc Dis. 2014;38(3):191-6. doi: 10.1159/000365653. Epub 2014 Oct 9.

PMID:
25300901
40.

[A mixed germ cell tumor that underwent dramatic size changes].

Kuwayama K, Takai H, Nishiyama A, Hirai S, Yokosuka K, Toi H, Hirano K, Matsubara S, Uno M, Nishimura H.

No Shinkei Geka. 2014 Sep;42(9):859-65. Japanese.

PMID:
25179200
41.

Application of a portable near infrared spectrometer for presumptive identification of psychoactive drugs.

Tsujikawa K, Yamamuro T, Kuwayama K, Kanamori T, Iwata YT, Miyamoto K, Kasuya F, Inoue H.

Forensic Sci Int. 2014 Sep;242:162-171. doi: 10.1016/j.forsciint.2014.05.020. Epub 2014 Jun 27.

PMID:
25058450
42.

Intestinal P-glycoprotein expression is multimodally regulated by intestinal ischemia-reperfusion.

Terada Y, Ogura J, Tsujimoto T, Kuwayama K, Koizumi T, Sasaki S, Maruyama H, Kobayashi M, Yamaguchi H, Iseki K.

J Pharm Pharm Sci. 2014;17(2):266-76.

43.

Utilization of matrix-assisted laser desorption/ionization imaging mass spectrometry to search for cannabis in herb mixtures.

Kuwayama K, Yamamuro T, Tsujikawa K, Miyaguchi H, Kanamori T, Iwata YT, Inoue H.

Anal Bioanal Chem. 2014 Jul;406(19):4789-94. doi: 10.1007/s00216-014-7881-x. Epub 2014 May 18.

PMID:
24838491
44.

Effect of oxidative stress on expression and function of human and rat organic anion transporting polypeptides in the liver.

Tsujimoto T, Ogura J, Kuwayama K, Koizumi T, Sasaki S, Terada Y, Kobayashi M, Yamaguchi H, Iseki K.

Int J Pharm. 2013 Oct 26. pii: S0378-5173(13)00896-X. doi: 10.1016/j.ijpharm.2013.10.013. [Epub ahead of print]

PMID:
24513548
45.

Effect of oxidative stress on expression and function of human and rat organic anion transporting polypeptides in the liver.

Tsujimoto T, Ogura J, Kuwayama K, Koizumi T, Sasaki S, Terada Y, Kobayashi M, Yamaguchi H, Iseki K.

Int J Pharm. 2013 Dec 31;458(2):262-71.

PMID:
24409515
46.

Intestinal ischemia-reperfusion suppresses biliary excretion of hepatic organic anion transporting polypeptides substrate.

Maruyama H, Ogura J, Fujikawa A, Terada Y, Tsujimoto T, Koizumi T, Kuwayama K, Kobayashi M, Yamaguchi H, Iseki K.

J Pharm Pharm Sci. 2013;16(5):722-31.

47.

Quercetin-3-rhamnoglucoside (rutin) stimulates transport of organic anion compounds mediated by organic anion transporting polypeptide 2B1.

Ogura J, Koizumi T, Segawa M, Yabe K, Kuwayama K, Sasaki S, Kaneko C, Tsujimoto T, Kobayashi M, Yamaguchi H, Iseki K.

Biopharm Drug Dispos. 2014 Apr;35(3):173-82. doi: 10.1002/bdd.1882. Epub 2014 Jan 14.

PMID:
24285294
48.

Thermal degradation of α-pyrrolidinopentiophenone during injection in gas chromatography/mass spectrometry.

Tsujikawa K, Kuwayama K, Kanamori T, Iwata YT, Inoue H.

Forensic Sci Int. 2013 Sep 10;231(1-3):296-9. doi: 10.1016/j.forsciint.2013.06.006. Epub 2013 Jul 6.

PMID:
23890652
49.

Microbleeds as a prognostic factor for acute subdural hematoma.

Yamaguchi T, Takai H, Hirai S, Yokosuka K, Toi H, Kuwayama K, Matsubara S, Hirano K, Uno M.

Neurol Med Chir (Tokyo). 2013;53(5):318-22.

50.

Applicability of chemically modified capillaries in chiral capillary electrophoresis for methamphetamine profiling.

Iwata YT, Mikuma T, Kuwayama K, Tsujikawa K, Miyaguchi H, Kanamori T, Inoue H.

Forensic Sci Int. 2013 Mar 10;226(1-3):235-9. doi: 10.1016/j.forsciint.2013.01.033. Epub 2013 Feb 16.

PMID:
23422168

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