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Items: 1 to 50 of 309

1.

Development and structural determination of an anti-PrPC aptamer that blocks pathological conformational conversion of prion protein.

Mashima T, Lee JH, Kamatari YO, Hayashi T, Nagata T, Nishikawa F, Nishikawa S, Kinoshita M, Kuwata K, Katahira M.

Sci Rep. 2020 Mar 18;10(1):4934. doi: 10.1038/s41598-020-61966-4.

2.

Designer Palmitoylation Motif-Based Self-Localizing Ligand for Sustained Control of Protein Localization in Living Cells and Caenorhabditis elegans.

Nakamura A, Oki C, Sawada S, Yoshii T, Kuwata K, Rudd AK, Devaraj NK, Noma K, Tsukiji S.

ACS Chem Biol. 2020 Mar 20. doi: 10.1021/acschembio.0c00014. [Epub ahead of print]

PMID:
32182034
3.

Engineering Orthogonal, Plasma Membrane-Specific SLIPT Systems for Multiplexed Chemical Control of Signaling Pathways in Living Single Cells.

Nakamura A, Oki C, Kato K, Fujinuma S, Maryu G, Kuwata K, Yoshii T, Matsuda M, Aoki K, Tsukiji S.

ACS Chem Biol. 2020 Mar 20. doi: 10.1021/acschembio.0c00024. [Epub ahead of print]

PMID:
32162909
4.

Effects of pyrroloquinoline quinone and imidazole pyrroloquinoline on biological activities and neural functions.

Yamada Y, Nishii K, Kuwata K, Nakamichi M, Nakanishi K, Sugimoto A, Ikemoto K.

Heliyon. 2020 Jan 29;6(1):e03240. doi: 10.1016/j.heliyon.2020.e03240. eCollection 2020 Jan.

5.
6.

DIUTHAME enables matrix-free mass spectrometry imaging of frozen tissue sections.

Kuwata K, Itou K, Kotani M, Ohmura T, Naito Y.

Rapid Commun Mass Spectrom. 2020 Jan 17:e8729. doi: 10.1002/rcm.8729. [Epub ahead of print]

PMID:
31951673
7.

Endoplasmic reticulum-derived bodies enable a single-cell chemical defense in Brassicaceae plants.

Yamada K, Goto-Yamada S, Nakazaki A, Kunieda T, Kuwata K, Nagano AJ, Nishimura M, Hara-Nishimura I.

Commun Biol. 2020 Jan 14;3(1):21. doi: 10.1038/s42003-019-0739-1.

8.

Kleptoprotein bioluminescence: Parapriacanthus fish obtain luciferase from ostracod prey.

Bessho-Uehara M, Yamamoto N, Shigenobu S, Mori H, Kuwata K, Oba Y.

Sci Adv. 2020 Jan 8;6(2):eaax4942. doi: 10.1126/sciadv.aax4942. eCollection 2020 Jan.

9.

HIGH STEROL ESTER 1 is a key factor in plant sterol homeostasis.

Shimada TL, Shimada T, Okazaki Y, Higashi Y, Saito K, Kuwata K, Oyama K, Kato M, Ueda H, Nakano A, Ueda T, Takano Y, Hara-Nishimura I.

Nat Plants. 2019 Nov;5(11):1154-1166. doi: 10.1038/s41477-019-0537-2. Epub 2019 Nov 11.

PMID:
31712757
10.

α-Synuclein chaperone suppresses nucleation and amyloidogenesis of prion protein.

Shirasaka M, Kuwata K, Honda R.

Biochem Biophys Res Commun. 2020 Jan 1;521(1):259-264. doi: 10.1016/j.bbrc.2019.10.120. Epub 2019 Oct 18.

PMID:
31635805
11.

Chemogenetic Control of Protein Anchoring to Endomembranes in Living Cells with Lipid-Tethered Small Molecules.

Nakamura A, Katahira R, Sawada S, Shinoda E, Kuwata K, Yoshii T, Tsukiji S.

Biochemistry. 2020 Jan 21;59(2):205-211. doi: 10.1021/acs.biochem.9b00807. Epub 2019 Oct 15.

PMID:
31578861
12.

Structure-function study of a novel inhibitor of the casein kinase 1 family in Arabidopsis thaliana.

Saito AN, Matsuo H, Kuwata K, Ono A, Kinoshita T, Yamaguchi J, Nakamichi N.

Plant Direct. 2019 Sep 17;3(9):e00172. doi: 10.1002/pld3.172. eCollection 2019 Sep.

13.

Chemical Synthesis of Atomically Tailored SUMO E2 Conjugating Enzymes for the Formation of Covalently Linked SUMO-E2-E3 Ligase Ternary Complexes.

Zhang Y, Hirota T, Kuwata K, Oishi S, Gramani SG, Bode JW.

J Am Chem Soc. 2019 Sep 18;141(37):14742-14751. doi: 10.1021/jacs.9b06820. Epub 2019 Sep 6.

PMID:
31436980
14.

LSD1-LIKE1-Mediated H3K4me2 Demethylation Is Required for Homologous Recombination Repair.

Hirakawa T, Kuwata K, Gallego ME, White CI, Nomoto M, Tada Y, Matsunaga S.

Plant Physiol. 2019 Oct;181(2):499-509. doi: 10.1104/pp.19.00530. Epub 2019 Jul 31.

PMID:
31366719
15.

Molecular Mechanism of Cellular Oxidative Stress Sensing by Keap1.

Suzuki T, Muramatsu A, Saito R, Iso T, Shibata T, Kuwata K, Kawaguchi SI, Iwawaki T, Adachi S, Suda H, Morita M, Uchida K, Baird L, Yamamoto M.

Cell Rep. 2019 Jul 16;28(3):746-758.e4. doi: 10.1016/j.celrep.2019.06.047.

16.

Casein kinase 1 family regulates PRR5 and TOC1 in the Arabidopsis circadian clock.

Uehara TN, Mizutani Y, Kuwata K, Hirota T, Sato A, Mizoi J, Takao S, Matsuo H, Suzuki T, Ito S, Saito AN, Nishiwaki-Ohkawa T, Yamaguchi-Shinozaki K, Yoshimura T, Kay SA, Itami K, Kinoshita T, Yamaguchi J, Nakamichi N.

Proc Natl Acad Sci U S A. 2019 Jun 4;116(23):11528-11536. doi: 10.1073/pnas.1903357116. Epub 2019 May 16.

17.

A designer molecular chaperone against transmissible spongiform encephalopathy slows disease progression in mice and macaques.

Yamaguchi K, Kamatari YO, Ono F, Shibata H, Fuse T, Elhelaly AE, Fukuoka M, Kimura T, Hosokawa-Muto J, Ishikawa T, Tobiume M, Takeuchi Y, Matsuyama Y, Ishibashi D, Nishida N, Kuwata K.

Nat Biomed Eng. 2019 Mar;3(3):206-219. doi: 10.1038/s41551-019-0349-8. Epub 2019 Feb 11.

PMID:
30948810
18.

Cell-based screen identifies a new potent and highly selective CK2 inhibitor for modulation of circadian rhythms and cancer cell growth.

Oshima T, Niwa Y, Kuwata K, Srivastava A, Hyoda T, Tsuchiya Y, Kumagai M, Tsuyuguchi M, Tamaru T, Sugiyama A, Ono N, Zolboot N, Aikawa Y, Oishi S, Nonami A, Arai F, Hagihara S, Yamaguchi J, Tama F, Kunisaki Y, Yagita K, Ikeda M, Kinoshita T, Kay SA, Itami K, Hirota T.

Sci Adv. 2019 Jan 23;5(1):eaau9060. doi: 10.1126/sciadv.aau9060. eCollection 2019 Jan.

19.

Development of a Nitric Oxide-Responsive Labeling Reagent for Proteome Analysis of Live Cells.

Nishikawa Y, Miki T, Awa M, Kuwata K, Tamura T, Hamachi I.

ACS Chem Biol. 2019 Mar 15;14(3):397-404. doi: 10.1021/acschembio.8b01021. Epub 2019 Feb 14.

PMID:
30715847
20.

Selective and reversible modification of kinase cysteines with chlorofluoroacetamides.

Shindo N, Fuchida H, Sato M, Watari K, Shibata T, Kuwata K, Miura C, Okamoto K, Hatsuyama Y, Tokunaga K, Sakamoto S, Morimoto S, Abe Y, Shiroishi M, Caaveiro JMM, Ueda T, Tamura T, Matsunaga N, Nakao T, Koyanagi S, Ohdo S, Yamaguchi Y, Hamachi I, Ono M, Ojida A.

Nat Chem Biol. 2019 Mar;15(3):250-258. doi: 10.1038/s41589-018-0204-3. Epub 2019 Jan 14.

PMID:
30643284
21.

A DISC1 point mutation promotes oligomerization and impairs information processing in a mouse model of schizophrenia.

Kakuda K, Niwa A, Honda R, Yamaguchi KI, Tomita H, Nojebuzzaman M, Hara A, Goto Y, Osawa M, Kuwata K.

J Biochem. 2019 Apr 1;165(4):369-378. doi: 10.1093/jb/mvy116.

PMID:
30561706
22.

A Covalent Inhibitor for Glutathione S-Transferase Pi (GSTP1-1 ) in Human Cells.

Shishido Y, Tomoike F, Kuwata K, Fujikawa H, Sekido Y, Murakami-Tonami Y, Kameda T, Abe N, Kimura Y, Shuto S, Abe H.

Chembiochem. 2019 Apr 1;20(7):900-905. doi: 10.1002/cbic.201800671. Epub 2019 Feb 15.

PMID:
30548113
23.

A femtomolar-range suicide germination stimulant for the parasitic plant Striga hermonthica.

Uraguchi D, Kuwata K, Hijikata Y, Yamaguchi R, Imaizumi H, Am S, Rakers C, Mori N, Akiyama K, Irle S, McCourt P, Kinoshita T, Ooi T, Tsuchiya Y.

Science. 2018 Dec 14;362(6420):1301-1305. doi: 10.1126/science.aau5445.

PMID:
30545887
24.

Chemical Profiling of the Endoplasmic Reticulum Proteome Using Designer Labeling Reagents.

Fujisawa A, Tamura T, Yasueda Y, Kuwata K, Hamachi I.

J Am Chem Soc. 2018 Dec 12;140(49):17060-17070. doi: 10.1021/jacs.8b08606. Epub 2018 Nov 28.

PMID:
30433779
25.

Doublecortin-like kinase 1 compromises DNA repair and induces chromosomal instability.

Lu Y, Maruyama J, Kuwata K, Fukuda H, Iwasa H, Arimoto-Matsuzaki K, Sugimura H, Hata Y.

Biochem Biophys Rep. 2018 Oct 30;16:130-137. doi: 10.1016/j.bbrep.2018.10.014. eCollection 2018 Dec.

26.

A valine-to-lysine substitution at position 210 induces structural conversion of prion protein into a β-sheet rich oligomer.

Kakuda K, Yamaguchi KI, Kuwata K, Honda R.

Biochem Biophys Res Commun. 2018 Nov 17;506(1):81-86. doi: 10.1016/j.bbrc.2018.10.075. Epub 2018 Oct 16.

PMID:
30336980
27.

Tissue-specific and intracellular localization of indican synthase from Polygonum tinctorium.

Inoue S, Morita R, Kuwata K, Kunieda T, Ueda H, Hara-Nishimura I, Minami Y.

Plant Physiol Biochem. 2018 Nov;132:138-144. doi: 10.1016/j.plaphy.2018.08.034. Epub 2018 Aug 28.

PMID:
30189417
28.

Poly-L-histidine inhibits prion propagation in a prion-infected cell line.

Honda R, Yamaguchi KI, Elhelaly AE, Fuji M, Kuwata K.

Prion. 2018;12(3-4):226-233. doi: 10.1080/19336896.2018.1505395. Epub 2018 Aug 17.

29.

Identification of Alprenolol Hydrochloride as an Anti-prion Compound Using Surface Plasmon Resonance Imaging.

Miyazaki Y, Ishikawa T, Kamatari YO, Nakagaki T, Takatsuki H, Ishibashi D, Kuwata K, Nishida N, Atarashi R.

Mol Neurobiol. 2019 Jan;56(1):367-377. doi: 10.1007/s12035-018-1088-7. Epub 2018 Apr 27.

PMID:
29704200
30.

Daidzein reductase of Eggerthella sp. YY7918, its octameric subunit structure containing FMN/FAD/4Fe-4S, and its enantioselective production of R-dihydroisoflavones.

Kawada Y, Goshima T, Sawamura R, Yokoyama SI, Yanase E, Niwa T, Ebihara A, Inagaki M, Yamaguchi K, Kuwata K, Kato Y, Sakurada O, Suzuki T.

J Biosci Bioeng. 2018 Sep;126(3):301-309. doi: 10.1016/j.jbiosc.2018.03.018. Epub 2018 Apr 23.

PMID:
29699942
31.

Discovery of Shoot Branching Regulator Targeting Strigolactone Receptor DWARF14.

Yoshimura M, Sato A, Kuwata K, Inukai Y, Kinoshita T, Itami K, Tsuchiya Y, Hagihara S.

ACS Cent Sci. 2018 Feb 28;4(2):230-234. doi: 10.1021/acscentsci.7b00554. Epub 2018 Feb 7.

32.

The Phosphate Fast-Responsive Genes PECP1 and PPsPase1 Affect Phosphocholine and Phosphoethanolamine Content.

Hanchi M, Thibaud MC, Légeret B, Kuwata K, Pochon N, Beisson F, Cao A, Cuyas L, David P, Doerner P, Ferjani A, Lai F, Li-Beisson Y, Mutterer J, Philibert M, Raghothama KG, Rivasseau C, Secco D, Whelan J, Nussaume L, Javot H.

Plant Physiol. 2018 Apr;176(4):2943-2962. doi: 10.1104/pp.17.01246. Epub 2018 Feb 23.

33.

Time-Course Transcriptomics Analysis Reveals Key Responses of Submerged Deepwater Rice to Flooding.

Minami A, Yano K, Gamuyao R, Nagai K, Kuroha T, Ayano M, Nakamori M, Koike M, Kondo Y, Niimi Y, Kuwata K, Suzuki T, Higashiyama T, Takebayashi Y, Kojima M, Sakakibara H, Toyoda A, Fujiyama A, Kurata N, Ashikari M, Reuscher S.

Plant Physiol. 2018 Apr;176(4):3081-3102. doi: 10.1104/pp.17.00858. Epub 2018 Feb 23.

34.

Molecular basis for diversification of yeast prion strain conformation.

Ohhashi Y, Yamaguchi Y, Kurahashi H, Kamatari YO, Sugiyama S, Uluca B, Piechatzek T, Komi Y, Shida T, Müller H, Hanashima S, Heise H, Kuwata K, Tanaka M.

Proc Natl Acad Sci U S A. 2018 Mar 6;115(10):2389-2394. doi: 10.1073/pnas.1715483115. Epub 2018 Feb 21.

35.

Quantum Chemical and Statistical Rate Theory Studies of the Vinyl Hydroperoxides Formed in trans-2-Butene and 2,3-Dimethyl-2-butene Ozonolysis.

Kuwata KT, Luu L, Weberg AB, Huang K, Parsons AJ, Peebles LA, Rackstraw NB, Kim MJ.

J Phys Chem A. 2018 Mar 8;122(9):2485-2502. doi: 10.1021/acs.jpca.8b00287. Epub 2018 Feb 21.

PMID:
29431443
36.

Acceleration of nucleation of prion protein during continuous ultrasonication.

Yamaguchi KI, Honda RP, Elhelaly AE, Kuwata K.

J Biochem. 2018 Jun 1;163(6):503-513. doi: 10.1093/jb/mvy015.

PMID:
29409004
37.

Evidence for a central role of PrP helix 2 in the nucleation of amyloid fibrils.

Honda R, Kuwata K.

FASEB J. 2018 Jul;32(7):3641-3652. doi: 10.1096/fj.201701183RR. Epub 2018 Feb 1.

PMID:
29401635
38.

Correction to Synthesis of Potent and Selective Inhibitors of Aldo-Keto Reductase 1B10 and Their Efficacy against Proliferation, Metastasis, and Cisplatin Resistance of Lung Cancer Cells.

Endo S, Xia S, Suyama M, Morikawa Y, Oguri H, Hu D, Ao Y, Takahara S, Horino Y, Hayakawa Y, Watanabe Y, Gouda H, Hara A, Kuwata K, Toyooka N, Matsunaga T, Ikari A.

J Med Chem. 2018 Feb 8;61(3):1380. doi: 10.1021/acs.jmedchem.7b01911. Epub 2018 Jan 11. No abstract available.

PMID:
29323483
39.

Drug-Excipient Interactions: Effect on Molecular Mobility and Physical Stability of Ketoconazole-Organic Acid Coamorphous Systems.

Fung MH, DeVault M, Kuwata KT, Suryanarayanan R.

Mol Pharm. 2018 Mar 5;15(3):1052-1061. doi: 10.1021/acs.molpharmaceut.7b00932. Epub 2018 Feb 16.

PMID:
29309158
40.

Formation and properties of amyloid fibrils of prion protein.

Yamaguchi KI, Kuwata K.

Biophys Rev. 2018 Apr;10(2):517-525. doi: 10.1007/s12551-017-0377-0. Epub 2017 Dec 4. Review.

41.

Protein-Ligand Dissociation Simulated by Parallel Cascade Selection Molecular Dynamics.

Tran DP, Takemura K, Kuwata K, Kitao A.

J Chem Theory Comput. 2018 Jan 9;14(1):404-417. doi: 10.1021/acs.jctc.7b00504. Epub 2017 Dec 8.

42.

Characterization of UDP-glucosyltransferase from Indigofera tinctoria.

Inoue S, Moriya T, Morita R, Kuwata K, Thul ST, Sarangi BK, Minami Y.

Plant Physiol Biochem. 2017 Dec;121:226-233. doi: 10.1016/j.plaphy.2017.11.002. Epub 2017 Nov 6.

PMID:
29156217
43.

Synthesis of Potent and Selective Inhibitors of Aldo-Keto Reductase 1B10 and Their Efficacy against Proliferation, Metastasis, and Cisplatin Resistance of Lung Cancer Cells.

Endo S, Xia S, Suyama M, Morikawa Y, Oguri H, Hu D, Ao Y, Takahara S, Horino Y, Hayakawa Y, Watanabe Y, Gouda H, Hara A, Kuwata K, Toyooka N, Matsunaga T, Ikari A.

J Med Chem. 2017 Oct 26;60(20):8441-8455. doi: 10.1021/acs.jmedchem.7b00830. Epub 2017 Oct 13. Erratum in: J Med Chem. 2018 Feb 8;61(3):1380.

PMID:
28976752
44.

The calcium-binding protein ALG-2 regulates protein secretion and trafficking via interactions with MISSL and MAP1B proteins.

Takahara T, Inoue K, Arai Y, Kuwata K, Shibata H, Maki M.

J Biol Chem. 2017 Oct 13;292(41):17057-17072. doi: 10.1074/jbc.M117.800201. Epub 2017 Sep 1.

45.

A covalent G-site inhibitor for glutathione S-transferase Pi (GSTP1-1).

Shishido Y, Tomoike F, Kimura Y, Kuwata K, Yano T, Fukui K, Fujikawa H, Sekido Y, Murakami-Tonami Y, Kameda T, Shuto S, Abe H.

Chem Commun (Camb). 2017 Oct 10;53(81):11138-11141. doi: 10.1039/c7cc05829b.

PMID:
28848941
46.

PNA monomers fully compatible with standard Fmoc-based solid-phase synthesis of pseudocomplementary PNA.

Sugiyama T, Hasegawa G, Niikura C, Kuwata K, Imamura Y, Demizu Y, Kurihara M, Kittaka A.

Bioorg Med Chem Lett. 2017 Aug 1;27(15):3337-3341. doi: 10.1016/j.bmcl.2017.06.015. Epub 2017 Jun 3.

PMID:
28610975
47.

β-catenin Mutations Are Not Involved in Early-stage Hepatocarcinogenesis Induced by Protoporphyrinogen Oxidase Inhibitors in Mice.

Kuwata K, Inoue K, Ichimura R, Takahashi M, Kodama Y, Shibutani M, Yoshida M.

Toxicol Pathol. 2017 Jun;45(4):493-505. doi: 10.1177/0192623317708898. Epub 2017 Jun 5.

PMID:
28580885
48.

The effect of rapamycin, NVP-BEZ235, aspirin, and metformin on PI3K/AKT/mTOR signaling pathway of PIK3CA-related overgrowth spectrum (PROS).

Suzuki Y, Enokido Y, Yamada K, Inaba M, Kuwata K, Hanada N, Morishita T, Mizuno S, Wakamatsu N.

Oncotarget. 2017 Jul 11;8(28):45470-45483. doi: 10.18632/oncotarget.17566.

49.

Drosophila Dalmatian combines sororin and shugoshin roles in establishment and protection of cohesion.

Yamada T, Tahara E, Kanke M, Kuwata K, Nishiyama T.

EMBO J. 2017 Jun 1;36(11):1513-1527. doi: 10.15252/embj.201695607. Epub 2017 May 8.

50.

Capsular polysaccharide inhibits adhesion of Bifidobacterium longum 105-A to enterocyte-like Caco-2 cells and phagocytosis by macrophages.

Tahoun A, Masutani H, El-Sharkawy H, Gillespie T, Honda RP, Kuwata K, Inagaki M, Yabe T, Nomura I, Suzuki T.

Gut Pathog. 2017 May 1;9:27. doi: 10.1186/s13099-017-0177-x. eCollection 2017.

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