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Items: 44


Emergence of carbapenem-resistant Pseudomonas asiatica producing NDM-1 and VIM-2 metallo-β-lactamases in Myanmar.

Tohya M, Tada T, Watanabe S, Kuwahara-Arai K, Zin KN, Zaw NN, Aung MY, Mya S, Zan KN, Kirikae T, Tin HH.

Antimicrob Agents Chemother. 2019 May 28. pii: AAC.00475-19. doi: 10.1128/AAC.00475-19. [Epub ahead of print]


Pseudomonas asiatica sp. nov., isolated from hospitalized patients in Japan and Myanmar.

Tohya M, Watanabe S, Teramoto K, Uechi K, Tada T, Kuwahara-Arai K, Kinjo T, Maeda S, Nakasone I, Zaw NN, Mya S, Zan KN, Tin HH, Fujita J, Kirikae T.

Int J Syst Evol Microbiol. 2019 May;69(5):1361-1368. doi: 10.1099/ijsem.0.003316. Epub 2019 Feb 27.


Molecular Characterization of Multidrug-Resistant Pseudomonas aeruginosa Isolates in Hospitals in Myanmar.

Tada T, Hishinuma T, Watanabe S, Uchida H, Tohya M, Kuwahara-Arai K, Mya S, Zan KN, Kirikae T, Tin HH.

Antimicrob Agents Chemother. 2019 Apr 25;63(5). pii: e02397-18. doi: 10.1128/AAC.02397-18. Print 2019 May.


An improved carbapenem inactivation method, CIMTrisII, for carbapenemase production by Gram-negative pathogens.

Uechi K, Tada T, Kuwahara-Arai K, Sekiguchi JI, Yanagisawa I, Tome T, Nakasone I, Maeda S, Mya S, Zan KN, Tin HH, Kirikae T, Fujita J.

J Med Microbiol. 2019 Feb;68(2):124-131. doi: 10.1099/jmm.0.000888. Epub 2018 Dec 10.


Faecal freezing preservation period influences colonization ability for faecal microbiota transplantation.

Takahashi M, Ishikawa D, Sasaki T, Lu YJ, Kuwahara-Arai K, Kamei M, Shibuya T, Osada T, Hiramatsu K, Nagahara A.

J Appl Microbiol. 2019 Mar;126(3):973-984. doi: 10.1111/jam.14167. Epub 2019 Jan 7.


Spread of GES-5 carbapenemase-producing Pseudomonas aeruginosa clinical isolates in Japan due to clonal expansion of ST235.

Hishinuma T, Tada T, Kuwahara-Arai K, Yamamoto N, Shimojima M, Kirikae T.

PLoS One. 2018 Nov 19;13(11):e0207134. doi: 10.1371/journal.pone.0207134. eCollection 2018.


The Microbial Composition of Bacteroidetes Species in Ulcerative Colitis Is Effectively Improved by Combination Therapy With Fecal Microbiota Transplantation and Antibiotics.

Ishikawa D, Sasaki T, Takahashi M, Kuwahara-Arai K, Haga K, Ito S, Okahara K, Nakajima A, Shibuya T, Osada T, Hiramatsu K, Watanabe S, Nagahara A.

Inflamm Bowel Dis. 2018 Nov 29;24(12):2590-2598. doi: 10.1093/ibd/izy266.


Development of a New Application for Comprehensive Viability Analysis Based on Microbiome Analysis by Next-Generation Sequencing: Insights into Staphylococcal Carriage in Human Nasal Cavities.

Lu YJ, Sasaki T, Kuwahara-Arai K, Uehara Y, Hiramatsu K.

Appl Environ Microbiol. 2018 May 17;84(11). pii: e00517-18. doi: 10.1128/AEM.00517-18. Print 2018 Jun 1.


A Modified Carbapenem Inactivation Method, CIMTris, for Carbapenemase Production in Acinetobacter and Pseudomonas Species.

Uechi K, Tada T, Shimada K, Kuwahara-Arai K, Arakaki M, Tome T, Nakasone I, Maeda S, Kirikae T, Fujita J.

J Clin Microbiol. 2017 Dec;55(12):3405-3410. doi: 10.1128/JCM.00893-17. Epub 2017 Sep 27.


Antimicrobial cathelicidin peptide LL‑37 induces NET formation and suppresses the inflammatory response in a mouse septic model.

Hosoda H, Nakamura K, Hu Z, Tamura H, Reich J, Kuwahara-Arai K, Iba T, Tabe Y, Nagaoaka I.

Mol Med Rep. 2017 Oct;16(4):5618-5626. doi: 10.3892/mmr.2017.7267. Epub 2017 Aug 17.


Evaluation of the effect of recombinant thrombomodulin on a lipopolysaccharide-induced murine sepsis model.

Takehara K, Murakami T, Kuwahara-Arai K, Iba T, Nagaoka I, Sakamoto K.

Exp Ther Med. 2017 Jun;13(6):2969-2974. doi: 10.3892/etm.2017.4308. Epub 2017 Apr 5.


Spleen-derived lipocalin-2 in the portal vein regulates Kupffer cells activation and attenuates the development of liver fibrosis in mice.

Aoyama T, Kuwahara-Arai K, Uchiyama A, Kon K, Okubo H, Yamashina S, Ikejima K, Kokubu S, Miyazaki A, Watanabe S.

Lab Invest. 2017 Aug;97(8):890-902. doi: 10.1038/labinvest.2017.44. Epub 2017 May 15.


Neutrophil extracellular traps induce IL-1β production by macrophages in combination with lipopolysaccharide.

Hu Z, Murakami T, Tamura H, Reich J, Kuwahara-Arai K, Iba T, Tabe Y, Nagaoka I.

Int J Mol Med. 2017 Mar;39(3):549-558. doi: 10.3892/ijmm.2017.2870. Epub 2017 Jan 27.


Changes in Intestinal Microbiota Following Combination Therapy with Fecal Microbial Transplantation and Antibiotics for Ulcerative Colitis.

Ishikawa D, Sasaki T, Osada T, Kuwahara-Arai K, Haga K, Shibuya T, Hiramatsu K, Watanabe S.

Inflamm Bowel Dis. 2017 Jan;23(1):116-125. doi: 10.1097/MIB.0000000000000975.


Antimicrobial cathelicidin peptide LL-37 inhibits the pyroptosis of macrophages and improves the survival of polybacterial septic mice.

Hu Z, Murakami T, Suzuki K, Tamura H, Reich J, Kuwahara-Arai K, Iba T, Nagaoka I.

Int Immunol. 2016 May;28(5):245-53. doi: 10.1093/intimm/dxv113. Epub 2016 Jan 7.


Human Host Defense Cathelicidin Peptide LL-37 Enhances the Lipopolysaccharide Uptake by Liver Sinusoidal Endothelial Cells without Cell Activation.

Suzuki K, Murakami T, Hu Z, Tamura H, Kuwahara-Arai K, Iba T, Nagaoka I.

J Immunol. 2016 Feb 1;196(3):1338-47. doi: 10.4049/jimmunol.1403203. Epub 2016 Jan 4.


Complete Genome Sequence of Methicillin-Resistant Staphylococcus schleiferi Strain TSCC54 of Canine Origin.

Sasaki T, Tsubakishita S, Kuwahara-Arai K, Matsuo M, Lu YJ, Tanaka Y, Hiramatsu K.

Genome Announc. 2015 Oct 29;3(5). pii: e01268-15. doi: 10.1128/genomeA.01268-15.


"Slow VISA," a novel phenotype of vancomycin resistance, found in vitro in heterogeneous vancomycin-intermediate Staphylococcus aureus strain Mu3.

Saito M, Katayama Y, Hishinuma T, Iwamoto A, Aiba Y, Kuwahara-Arai K, Cui L, Matsuo M, Aritaka N, Hiramatsu K.

Antimicrob Agents Chemother. 2014 Sep;58(9):5024-35. doi: 10.1128/AAC.02470-13. Epub 2014 May 19.


Antimicrobial cathelicidin peptide LL-37 inhibits the LPS/ATP-induced pyroptosis of macrophages by dual mechanism.

Hu Z, Murakami T, Suzuki K, Tamura H, Kuwahara-Arai K, Iba T, Nagaoka I.

PLoS One. 2014 Jan 16;9(1):e85765. doi: 10.1371/journal.pone.0085765. eCollection 2014.


Genomic Basis for Methicillin Resistance in Staphylococcus aureus.

Hiramatsu K, Ito T, Tsubakishita S, Sasaki T, Takeuchi F, Morimoto Y, Katayama Y, Matsuo M, Kuwahara-Arai K, Hishinuma T, Baba T.

Infect Chemother. 2013 Jun;45(2):117-36. doi: 10.3947/ic.2013.45.2.117. Epub 2013 Jun 26. Review.


Staphylococcal Cassette Chromosome mec (SCCmec) analysis of MRSA.

Ito T, Kuwahara-Arai K, Katayama Y, Uehara Y, Han X, Kondo Y, Hiramatsu K.

Methods Mol Biol. 2014;1085:131-48. doi: 10.1007/978-1-62703-664-1_8.


Investigation of nasal meticillin-resistant Staphylococcus aureus carriage in a haemodialysis clinic in Japan.

Uehara Y, Kuwahara-Arai K, Hori S, Kikuchi K, Yanai M, Hiramatsu K.

J Hosp Infect. 2013 May;84(1):81-4. doi: 10.1016/j.jhin.2013.01.004. Epub 2013 Feb 16.


Rapid and accurate identification of human-associated staphylococci by use of multiplex PCR.

Hirotaki S, Sasaki T, Kuwahara-Arai K, Hiramatsu K.

J Clin Microbiol. 2011 Oct;49(10):3627-31. doi: 10.1128/JCM.00488-11. Epub 2011 Aug 10.


Human anti-microbial cathelicidin peptide LL-37 suppresses the LPS-induced apoptosis of endothelial cells.

Suzuki K, Murakami T, Kuwahara-Arai K, Tamura H, Hiramatsu K, Nagaoka I.

Int Immunol. 2011 Mar;23(3):185-93. doi: 10.1093/intimm/dxq471.


Transcription and translation products of the cytolysin gene psm-mec on the mobile genetic element SCCmec regulate Staphylococcus aureus virulence.

Kaito C, Saito Y, Nagano G, Ikuo M, Omae Y, Hanada Y, Han X, Kuwahara-Arai K, Hishinuma T, Baba T, Ito T, Hiramatsu K, Sekimizu K.

PLoS Pathog. 2011 Feb 3;7(2):e1001267. doi: 10.1371/journal.ppat.1001267.


Origin and molecular evolution of the determinant of methicillin resistance in staphylococci.

Tsubakishita S, Kuwahara-Arai K, Sasaki T, Hiramatsu K.

Antimicrob Agents Chemother. 2010 Oct;54(10):4352-9. doi: 10.1128/AAC.00356-10. Epub 2010 Aug 2. Erratum in: Antimicrob Agents Chemother. 2011 Feb;55(2):946.


Staphylococcal cassette chromosome mec-like element in Macrococcus caseolyticus.

Tsubakishita S, Kuwahara-Arai K, Baba T, Hiramatsu K.

Antimicrob Agents Chemother. 2010 Apr;54(4):1469-75. doi: 10.1128/AAC.00575-09. Epub 2010 Jan 19.


Antimicrobial cathelicidin polypeptide CAP11 suppresses the production and release of septic mediators in D-galactosamine-sensitized endotoxin shock mice.

Murakami T, Obata T, Kuwahara-Arai K, Tamura H, Hiramatsu K, Nagaoka I.

Int Immunol. 2009 Aug;21(8):905-12. doi: 10.1093/intimm/dxp057. Epub 2009 Jun 25.


Augmentation of the antimicrobial activities of guinea pig cathelicidin CAP11-derived peptides by amino acid substitutions.

Okuda D, Yomogida S, Kuwahara-Arai K, Hitamatsu K, Tamura H, Nagaoka I.

Int J Mol Med. 2009 Apr;23(4):501-8.


Complete genome sequence of Macrococcus caseolyticus strain JCSCS5402, [corrected] reflecting the ancestral genome of the human-pathogenic staphylococci.

Baba T, Kuwahara-Arai K, Uchiyama I, Takeuchi F, Ito T, Hiramatsu K.

J Bacteriol. 2009 Feb;191(4):1180-90. doi: 10.1128/JB.01058-08. Epub 2008 Dec 12. Erratum in: J Bacteriol. 2009 May;191(10):3429.


Extreme genetic diversity of methicillin-resistant Staphylococcus epidermidis strains disseminated among healthy Japanese children.

Jamaluddin TZ, Kuwahara-Arai K, Hisata K, Terasawa M, Cui L, Baba T, Sotozono C, Kinoshita S, Ito T, Hiramatsu K.

J Clin Microbiol. 2008 Nov;46(11):3778-83. doi: 10.1128/JCM.02262-07. Epub 2008 Oct 1.


Antibacterial cathelicidin peptide CAP11 suppresses the anandamide production from lipopolysaccharide-stimulated mononuclear phagocytes.

Murakami T, Yomogida S, Someya A, Kuwahara-Arai K, Tamura H, Nagaoka I.

FEBS Lett. 2007 Jan 9;581(1):140-4. Epub 2006 Dec 14.


Dissemination of methicillin-resistant staphylococci among healthy Japanese children.

Hisata K, Kuwahara-Arai K, Yamanoto M, Ito T, Nakatomi Y, Cui L, Baba T, Terasawa M, Sotozono C, Kinoshita S, Yamashiro Y, Hiramatsu K.

J Clin Microbiol. 2005 Jul;43(7):3364-72.


Augmentation of the bactericidal activities of human cathelicidin CAP18/LL-37-derived antimicrobial peptides by amino acid substitutions.

Nagaoka I, Kuwahara-Arai K, Tamura H, Hiramatsu K, Hirata M.

Inflamm Res. 2005 Feb;54(2):66-73.


Has vancomycin-resistant Staphylococcus aureus started going it alone?

Hiramatsu K, Cui L, Kuwahara-Arai K.

Lancet. 2004 Aug 14-20;364(9434):565-6. No abstract available.


Physiological and molecular analysis of a mecA-negative Staphylococcus aureus clinical strain that expresses heterogeneous methicillin resistance.

Yoshida R, Kuwahara-Arai K, Baba T, Cui L, Richardson JF, Hiramatsu K.

J Antimicrob Chemother. 2003 Feb;51(2):247-55.


Eagle-type methicillin resistance: new phenotype of high methicillin resistance under mec regulator gene control.

Kondo N, Kuwahara-Arai K, Kuroda-Murakami H, Tateda-Suzuki E, Hiramatsu K.

Antimicrob Agents Chemother. 2001 Mar;45(3):815-24.


Contribution of a thickened cell wall and its glutamine nonamidated component to the vancomycin resistance expressed by Staphylococcus aureus Mu50.

Cui L, Murakami H, Kuwahara-Arai K, Hanaki H, Hiramatsu K.

Antimicrob Agents Chemother. 2000 Sep;44(9):2276-85.


Activated cell-wall synthesis is associated with vancomycin resistance in methicillin-resistant Staphylococcus aureus clinical strains Mu3 and Mu50.

Hanaki H, Kuwahara-Arai K, Boyle-Vavra S, Daum RS, Labischinski H, Hiramatsu K.

J Antimicrob Chemother. 1998 Aug;42(2):199-209.


[Mechanism of vancomycin resistance in MRSA strain Mu50].

Hanaki H, Labischinski H, Sasaki K, Kuwahara-Arai K, Inaba Y, Hiramatsu K.

Jpn J Antibiot. 1998 Mar;51(3):237-47. Japanese.


Distribution of mec regulator genes in methicillin-resistant Staphylococcus clinical strains.

Suzuki E, Kuwahara-Arai K, Richardson JF, Hiramatsu K.

Antimicrob Agents Chemother. 1993 Jun;37(6):1219-26.

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