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Items: 15


Mitochondrial transport proteins RHOT1 and RHOT2 serve as docking sites for PRKN-mediated mitophagy.

Safiulina D, Kuum M, Choubey V, Hickey MA, Kaasik A.

Autophagy. 2019 Feb 26:1-2. doi: 10.1080/15548627.2019.1586260. [Epub ahead of print]


Miro proteins prime mitochondria for Parkin translocation and mitophagy.

Safiulina D, Kuum M, Choubey V, Gogichaishvili N, Liiv J, Hickey MA, Cagalinec M, Mandel M, Zeb A, Liiv M, Kaasik A.

EMBO J. 2019 Jan 15;38(2). pii: e99384. doi: 10.15252/embj.201899384. Epub 2018 Nov 30.


Role of Mitochondrial Dynamics in Neuronal Development: Mechanism for Wolfram Syndrome.

Cagalinec M, Liiv M, Hodurova Z, Hickey MA, Vaarmann A, Mandel M, Zeb A, Choubey V, Kuum M, Safiulina D, Vasar E, Veksler V, Kaasik A.

PLoS Biol. 2016 Jul 19;14(7):e1002511. doi: 10.1371/journal.pbio.1002511. eCollection 2016 Jul.


Introductory letter from the Presidents of the Latvian, Estonian and Lithuanian Societies of Pharmacology.

Jansone B, Kuum M, Maciulaitis R.

Pharmacol Res. 2016 Nov;113(Pt B):721-722. doi: 10.1016/j.phrs.2016.06.006. Epub 2016 Jun 8. No abstract available.


Pharmacology in Estonia, Latvia and Lithuania: From historical roots to nowadays achievements.

Jansone B, Kuum M, Maciulaitis R.

Pharmacol Res. 2016 Nov;113(Pt B):723-730. doi: 10.1016/j.phrs.2016.04.024. Epub 2016 May 7. Review.


Mitochondrial biogenesis is required for axonal growth.

Vaarmann A, Mandel M, Zeb A, Wareski P, Liiv J, Kuum M, Antsov E, Liiv M, Cagalinec M, Choubey V, Kaasik A.

Development. 2016 Jun 1;143(11):1981-92. doi: 10.1242/dev.128926. Epub 2016 Apr 27.


Potassium fluxes across the endoplasmic reticulum and their role in endoplasmic reticulum calcium homeostasis.

Kuum M, Veksler V, Kaasik A.

Cell Calcium. 2015 Jul;58(1):79-85. doi: 10.1016/j.ceca.2014.11.004. Epub 2014 Nov 15. Review.


BECN1 is involved in the initiation of mitophagy: it facilitates PARK2 translocation to mitochondria.

Choubey V, Cagalinec M, Liiv J, Safiulina D, Hickey MA, Kuum M, Liiv M, Anwar T, Eskelinen EL, Kaasik A.

Autophagy. 2014 Jun;10(6):1105-19. doi: 10.4161/auto.28615.


Endoplasmic reticulum potassium-hydrogen exchanger and small conductance calcium-activated potassium channel activities are essential for ER calcium uptake in neurons and cardiomyocytes.

Kuum M, Veksler V, Liiv J, Ventura-Clapier R, Kaasik A.

J Cell Sci. 2012 Feb 1;125(Pt 3):625-33. doi: 10.1242/jcs.090126. Epub 2012 Feb 13.


Mutant A53T alpha-synuclein induces neuronal death by increasing mitochondrial autophagy.

Choubey V, Safiulina D, Vaarmann A, Cagalinec M, Wareski P, Kuum M, Zharkovsky A, Kaasik A.

J Biol Chem. 2011 Mar 25;286(12):10814-24. doi: 10.1074/jbc.M110.132514. Epub 2011 Jan 20.


Mitochondria as a source of mechanical signals in cardiomyocytes.

Kaasik A, Kuum M, Joubert F, Wilding J, Ventura-Clapier R, Veksler V.

Cardiovasc Res. 2010 Jul 1;87(1):83-91. doi: 10.1093/cvr/cvq039. Epub 2010 Feb 2.


PGC-1{alpha} and PGC-1{beta} regulate mitochondrial density in neurons.

Wareski P, Vaarmann A, Choubey V, Safiulina D, Liiv J, Kuum M, Kaasik A.

J Biol Chem. 2009 Aug 7;284(32):21379-85. doi: 10.1074/jbc.M109.018911. Epub 2009 Jun 19.


Energetic state is a strong regulator of sarcoplasmic reticulum Ca2+ loss in cardiac muscle: different efficiencies of different energy sources.

Kuum M, Kaasik A, Joubert F, Ventura-Clapier R, Veksler V.

Cardiovasc Res. 2009 Jul 1;83(1):89-96. doi: 10.1093/cvr/cvp125. Epub 2009 Apr 23.


Mitochondrial swelling impairs the transport of organelles in cerebellar granule neurons.

Kaasik A, Safiulina D, Choubey V, Kuum M, Zharkovsky A, Veksler V.

J Biol Chem. 2007 Nov 9;282(45):32821-6. Epub 2007 Sep 4.


Seizures, ataxia, and neuronal loss in cystatin B heterozygous mice.

Kaasik A, Kuum M, Aonurm A, Kalda A, Vaarmann A, Zharkovsky A.

Epilepsia. 2007 Apr;48(4):752-7. Epub 2007 Feb 23.

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