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Items: 1 to 50 of 55

1.

Randomized phase II trial of survivin 2B peptide vaccination for patients with HLA-A24-positive pancreatic adenocarcinoma.

Shima H, Tsurita G, Wada S, Hirohashi Y, Yasui H, Hayashi H, Miyakoshi T, Watanabe K, Murai A, Asanuma H, Tokita S, Kubo T, Nakatsugawa M, Kanaseki T, Tsukahara T, Nakae Y, Sugita O, Ito YM, Ota Y, Kimura Y, Kutomi G, Hirata K, Mizuguchi T, Imai K, Takemasa I, Sato N, Torigoe T.

Cancer Sci. 2019 Aug;110(8):2378-2385. doi: 10.1111/cas.14106. Epub 2019 Jul 23.

2.

Influence of XRCC4 expression by breast cancer cells on ipsilateral recurrence after breast-conserving therapy.

Kitagawa M, Someya M, Hasegawa T, Mikami T, Asaishi K, Hasegawa T, Matsumoto Y, Kutomi G, Takemasa I, Sakata KI.

Strahlenther Onkol. 2019 Jul;195(7):648-658. doi: 10.1007/s00066-019-01468-z. Epub 2019 Apr 17.

PMID:
30997540
3.

A genome-wide association study identifies three novel genetic markers for response to tamoxifen: A prospective multicenter study.

Onishi H, Udagawa C, Kubo M, Nakamura S, Akashi-Tanaka S, Kuwayama T, Watanabe C, Takamaru T, Takei H, Ishikawa T, Miyahara K, Matsumoto H, Hasegawa Y, Momozawa Y, Low SK, Kutomi G, Shima H, Satomi F, Okazaki M, Zaha H, Onomura M, Matsukata A, Sagara Y, Baba S, Yamada A, Shimada K, Shimizu D, Tsugawa K, Shimo A, Hartman M, Chan CW, Lee SC, Endo I, Zembutsu H.

PLoS One. 2018 Aug 30;13(8):e0201606. doi: 10.1371/journal.pone.0201606. eCollection 2018.

4.

Case report: Long-term survival of a pancreatic cancer patient immunized with an SVN-2B peptide vaccine.

Shima H, Kutomi G, Satomi F, Imamura M, Kimura Y, Mizuguchi T, Watanabe K, Takahashi A, Murai A, Tsukahara T, Kanaseki T, Hirohashi Y, Iwayama Y, Tsuruma T, Kameshima H, Sato N, Torigoe T, Takemasa I.

Cancer Immunol Immunother. 2018 Oct;67(10):1603-1609. doi: 10.1007/s00262-018-2217-x. Epub 2018 Aug 1.

5.

Comparison of surgical outcomes and complications between the Harmonic FOCUS and conventional surgery for open thyroidectomy.

Maeda H, Kutomi G, Satomi F, Shima H, Mori M, Takemasa I.

Mol Clin Oncol. 2018 Apr;8(4):557-560. doi: 10.3892/mco.2018.1569. Epub 2018 Feb 7.

6.

ST6GALNAC1 plays important roles in enhancing cancer stem phenotypes of colorectal cancer via the Akt pathway.

Ogawa T, Hirohashi Y, Murai A, Nishidate T, Okita K, Wang L, Ikehara Y, Satoyoshi T, Usui A, Kubo T, Nakastugawa M, Kanaseki T, Tsukahara T, Kutomi G, Furuhata T, Hirata K, Sato N, Mizuguchi T, Takemasa I, Torigoe T.

Oncotarget. 2017 Nov 8;8(68):112550-112564. doi: 10.18632/oncotarget.22545. eCollection 2017 Dec 22.

7.

Current status of the prognostic molecular biomarkers in breast cancer: A systematic review.

Kutomi G, Mizuguchi T, Satomi F, Maeda H, Shima H, Kimura Y, Hirata K.

Oncol Lett. 2017 Mar;13(3):1491-1498. doi: 10.3892/ol.2017.5609. Epub 2017 Jan 17.

8.

LY6/PLAUR domain containing 3 has a role in the maintenance of colorectal cancer stem-like cells.

Wang L, Hirohashi Y, Ogawa T, Shen M, Takeda R, Murai A, Yamamoto E, Kubo T, Nakatsugawa M, Kanaseki T, Tsukahara T, Nishidate T, Okita K, Kutomi G, Sato N, Takemasa I, Torigoe T.

Biochem Biophys Res Commun. 2017 Apr 29;486(2):232-238. doi: 10.1016/j.bbrc.2017.02.112. Epub 2017 Feb 24.

PMID:
28238780
9.

Identification and functional analysis of variants of a cancer/testis antigen LEMD1 in colorectal cancer stem-like cells.

Takeda R, Hirohashi Y, Shen M, Wang L, Ogawa T, Murai A, Yamamoto E, Kubo T, Nakatsugawa M, Kanaseki T, Tsukahara T, Nishidate T, Okita K, Kutomi G, Sato N, Takemasa I, Torigoe T.

Biochem Biophys Res Commun. 2017 Apr 8;485(3):651-657. doi: 10.1016/j.bbrc.2017.02.081. Epub 2017 Feb 20.

PMID:
28219643
10.

Cancer-associated oxidoreductase ERO1-α promotes immune escape through up-regulation of PD-L1 in human breast cancer.

Tanaka T, Kutomi G, Kajiwara T, Kukita K, Kochin V, Kanaseki T, Tsukahara T, Hirohashi Y, Torigoe T, Okamoto Y, Hirata K, Sato N, Tamura Y.

Oncotarget. 2017 Apr 11;8(15):24706-24718. doi: 10.18632/oncotarget.14960.

11.

Significant Effect of Polymorphisms in CYP2D6 on Response to Tamoxifen Therapy for Breast Cancer: A Prospective Multicenter Study.

Zembutsu H, Nakamura S, Akashi-Tanaka S, Kuwayama T, Watanabe C, Takamaru T, Takei H, Ishikawa T, Miyahara K, Matsumoto H, Hasegawa Y, Kutomi G, Shima H, Satomi F, Okazaki M, Zaha H, Onomura M, Matsukata A, Sagara Y, Baba S, Yamada A, Shimada K, Shimizu D, Tsugawa K, Shimo A, Tan EY, Hartman M, Chan CW, Lee SC, Nakamura Y.

Clin Cancer Res. 2017 Apr 15;23(8):2019-2026. doi: 10.1158/1078-0432.CCR-16-1779. Epub 2016 Oct 19.

12.

Hypoxia augments MHC class I antigen presentation via facilitation of ERO1-α-mediated oxidative folding in murine tumor cells.

Kajiwara T, Tanaka T, Kukita K, Kutomi G, Saito K, Okuya K, Takaya A, Kochin V, Kanaseki T, Tsukahara T, Hirohashi Y, Torigoe T, Hirata K, Sato N, Tamura Y.

Eur J Immunol. 2016 Dec;46(12):2842-2851. doi: 10.1002/eji.201646525. Epub 2016 Oct 18.

13.

Clinicopathological characteristics of thyroid cancer misdiagnosed by fine needle aspiration.

Maeda H, Kutomi G, Satomi F, Shima H, Mori M, Hirata K, Takemasa I.

Exp Ther Med. 2016 Oct;12(4):2766-2772. Epub 2016 Sep 1.

14.

SOX2 and ALDH1 as Predictors of Operable Breast Cancer.

Shima H, Kutomi G, Satomi F, Maeda H, Hirohashi Y, Hasegawa T, Mori M, Torigoe T, Takemasa I.

Anticancer Res. 2016 Jun;36(6):2945-53.

PMID:
27272809
15.

Flap revascularization in patients following immediate reconstruction using an autologous free dermal fat graft for breast cancer: a report of two cases.

Shima H, Kutomi G, Kyuno T, Satomi F, Uno S, Maeda H, Kameshima H, Omura T, Kimura Y, Mizuguchi T, Hirata K, Takemasa I.

Surg Case Rep. 2016 Dec;2(1):54. doi: 10.1186/s40792-016-0181-2. Epub 2016 Jun 3.

16.

Cancer-associated oxidoreductase ERO1-α drives the production of VEGF via oxidative protein folding and regulating the mRNA level.

Tanaka T, Kutomi G, Kajiwara T, Kukita K, Kochin V, Kanaseki T, Tsukahara T, Hirohashi Y, Torigoe T, Okamoto Y, Hirata K, Sato N, Tamura Y.

Br J Cancer. 2016 May 24;114(11):1227-34. doi: 10.1038/bjc.2016.105. Epub 2016 Apr 21.

17.

RNA helicase YTHDC2 promotes cancer metastasis via the enhancement of the efficiency by which HIF-1α mRNA is translated.

Tanabe A, Tanikawa K, Tsunetomi M, Takai K, Ikeda H, Konno J, Torigoe T, Maeda H, Kutomi G, Okita K, Mori M, Sahara H.

Cancer Lett. 2016 Jun 28;376(1):34-42. doi: 10.1016/j.canlet.2016.02.022. Epub 2016 Mar 17.

PMID:
26996300
18.

The Japanese Breast Cancer Society clinical practice guideline for surgical treatment of breast cancer, 2015 edition.

Jinno H, Inokuchi M, Ito T, Kitamura K, Kutomi G, Sakai T, Kijima Y, Wada N, Ito Y, Mukai H.

Breast Cancer. 2016 May;23(3):367-77. doi: 10.1007/s12282-016-0671-x. Epub 2016 Feb 26. No abstract available.

PMID:
26921084
19.

Olfactory Receptor Family 7 Subfamily C Member 1 Is a Novel Marker of Colon Cancer-Initiating Cells and Is a Potent Target of Immunotherapy.

Morita R, Hirohashi Y, Torigoe T, Ito-Inoda S, Takahashi A, Mariya T, Asanuma H, Tamura Y, Tsukahara T, Kanaseki T, Kubo T, Kutomi G, Mizuguchi T, Terui T, Ishitani K, Hashino S, Kondo T, Minagawa N, Takahashi N, Taketomi A, Todo S, Asaka M, Sato N.

Clin Cancer Res. 2016 Jul 1;22(13):3298-309. doi: 10.1158/1078-0432.CCR-15-1709. Epub 2016 Feb 9.

20.

CpG-A stimulates Hsp72 secretion from plasmacytoid dendritic cells, facilitating cross-presentation.

Tanaka T, Kajiwara T, Kutomi G, Kurotaki T, Saito K, Kanaseki T, Tsukahara T, Hirohashi Y, Torigoe T, Hirata K, Okamoto Y, Sato N, Tamura Y.

Immunol Lett. 2015 Sep;167(1):34-40. doi: 10.1016/j.imlet.2015.06.014. Epub 2015 Jun 30.

PMID:
26141624
21.

Evaluation of the validity of chemotherapy-induced nausea and vomiting assessment in outpatients using the Japanese version of the MASCC antiemesis tool.

Matsuda Y, Okita K, Furuhata T, Kutomi G, Yamashita K, Sato Y, Takimoto R, Hirata K.

Support Care Cancer. 2015 Nov;23(11):3331-9. doi: 10.1007/s00520-015-2780-z. Epub 2015 May 24.

PMID:
26003425
22.

[Adjuvant hormonal treatment for estrogen receptor-positive breast cancer-a questionnaire survey conducted by Japanese breast cancer society-authorized facilities in Hokkaido].

Takahashi M, Ohmura T, Kitada M, Kutomi G, Hosoda M, Masuoka H, Watanabe K, Watanabe Y, Yamashita H, Hirata K.

Gan To Kagaku Ryoho. 2015 May;42(5):575-9. Japanese.

PMID:
25981650
23.

Heat shock protein 90 associates with Toll-like receptors 7/9 and mediates self-nucleic acid recognition in SLE.

Saito K, Kukita K, Kutomi G, Okuya K, Asanuma H, Tabeya T, Naishiro Y, Yamamoto M, Takahashi H, Torigoe T, Nakai A, Shinomura Y, Hirata K, Sato N, Tamura Y.

Eur J Immunol. 2015 Jul;45(7):2028-41. doi: 10.1002/eji.201445293. Epub 2015 Apr 28.

24.

Cancer-Associated Oxidase ERO1-α Regulates the Expression of MHC Class I Molecule via Oxidative Folding.

Kukita K, Tamura Y, Tanaka T, Kajiwara T, Kutomi G, Saito K, Okuya K, Takaya A, Kanaseki T, Tsukahara T, Hirohashi Y, Torigoe T, Furuhata T, Hirata K, Sato N.

J Immunol. 2015 May 15;194(10):4988-96. doi: 10.4049/jimmunol.1303228. Epub 2015 Apr 13.

25.

Trials of vaccines for pancreatic ductal adenocarcinoma: Is there any hope of an improved prognosis?

Mizuguchi T, Torigoe T, Satomi F, Shima H, Kutomi G, Ota S, Ishii M, Hayashi H, Asakura S, Hirohashi Y, Meguro M, Kimura Y, Nishidate T, Okita K, Ishino M, Miyamoto A, Hatakenaka M, Sato N, Hirata K.

Surg Today. 2016 Feb;46(2):139-48. doi: 10.1007/s00595-015-1120-8. Epub 2015 Feb 5. Review.

PMID:
25649538
26.

Synchronous Paget disease of the breast and axilla.

Kobayashi K, Sumikawa Y, Kikuchi Y, Kan Y, Kato J, Satomi F, Shima H, Kutomi G, Yamashita T.

J Am Acad Dermatol. 2015 Jan;72(1):e44-5. doi: 10.1016/j.jaad.2014.09.053. No abstract available.

27.

Heat shock protein 90 targets a chaperoned peptide to the static early endosome for efficient cross-presentation by human dendritic cells.

Tanaka T, Okuya K, Kutomi G, Takaya A, Kajiwara T, Kanaseki T, Tsukahara T, Hirohashi Y, Torigoe T, Hirata K, Okamoto Y, Sato N, Tamura Y.

Cancer Sci. 2015 Jan;106(1):18-24. doi: 10.1111/cas.12570. Epub 2014 Dec 15.

28.

Relation of serum adiponectin levels and obesity with breast cancer: a Japanese case-control study.

Minatoya M, Kutomi G, Shima H, Asakura S, Otokozawa S, Ohnishi H, Akasaka H, Miura T, Mori M, Hirata K.

Asian Pac J Cancer Prev. 2014;15(19):8325-30.

29.

Risk of node metastasis of sentinel lymph nodes detected in level II/III of the axilla by single-photon emission computed tomography/computed tomography.

Shima H, Kutomi G, Satomi F, Maeda H, Takamaru T, Kameshima H, Omura T, Mori M, Hatakenaka M, Hasegawa T, Hirata K.

Exp Ther Med. 2014 Nov;8(5):1447-1452. Epub 2014 Sep 15.

30.

Tumor-α9β1 integrin-mediated signaling induces breast cancer growth and lymphatic metastasis via the recruitment of cancer-associated fibroblasts.

Ota D, Kanayama M, Matsui Y, Ito K, Maeda N, Kutomi G, Hirata K, Torigoe T, Sato N, Takaoka A, Chambers AF, Morimoto J, Uede T.

J Mol Med (Berl). 2014 Dec;92(12):1271-81. doi: 10.1007/s00109-014-1183-9. Epub 2014 Aug 8.

PMID:
25099519
31.

Japan Breast Cancer Society clinical practice guideline for surgical treatment of breast cancer.

Komoike Y, Inokuchi M, Itoh T, Kitamura K, Kutomi G, Sakai T, Jinno H, Wada N, Ohsumi S, Mukai H; Japanese Breast Cancer Society.

Breast Cancer. 2015 Jan;22(1):37-48. doi: 10.1007/s12282-014-0558-7. Epub 2014 Aug 5. No abstract available.

PMID:
25091115
32.

A phase I study of combination therapy with nanoparticle albumin-bound paclitaxel and cyclophosphamide in patients with metastatic or recurrent breast cancer.

Kutomi G, Ohmura T, Satomi F, Maeda H, Shima H, Kameshima H, Okazaki M, Masuoka H, Sasaki K, Hirata K.

Int J Clin Oncol. 2015 Jun;20(3):474-9. doi: 10.1007/s10147-014-0725-z. Epub 2014 Jul 30.

PMID:
25073954
33.

Lymph node shape in computed tomography imaging as a predictor for axillary lymph node metastasis in patients with breast cancer.

Kutomi G, Ohmura T, Satomi F, Takamaru T, Shima H, Suzuki Y, Otokozawa S, Zembutsu H, Mori M, Hirata K.

Exp Ther Med. 2014 Aug;8(2):681-685. Epub 2014 Jun 16.

34.

Use of the dye-guided sentinel lymph node biopsy method alone for breast cancer metastasis to avoid unnecessary axillary lymph node dissection.

Takamaru T, Kutomi G, Satomi F, Shima H, Ohno K, Kameshima H, Suzuki Y, Ohmura T, Takamaru H, Nojima M, Mori M, Hirata K.

Exp Ther Med. 2014 Feb;7(2):456-460. Epub 2013 Dec 11.

35.

Relationship of serum isoflavone, insulin and adiponectin levels with breast cancer risk.

Minatoya M, Kutomi G, Asakura S, Otokozawa S, Sugiyama Y, Ohnishi H, Akasaka H, Miura T, Mori M, Hirata K.

Breast Cancer. 2015 Sep;22(5):452-61. doi: 10.1007/s12282-013-0502-2. Epub 2013 Oct 29.

PMID:
24166746
36.

Equol, adiponectin, insulin levels and risk of breast cancer.

Minatoya M, Kutomi G, Asakura S, Otokozawa S, Sugiyama Y, Nagata Y, Mori M, Hirata K.

Asian Pac J Cancer Prev. 2013;14(4):2191-9. Review.

37.

Human endoplasmic reticulum oxidoreductin 1-α is a novel predictor for poor prognosis of breast cancer.

Kutomi G, Tamura Y, Tanaka T, Kajiwara T, Kukita K, Ohmura T, Shima H, Takamaru T, Satomi F, Suzuki Y, Torigoe T, Sato N, Hirata K.

Cancer Sci. 2013 Aug;104(8):1091-6. doi: 10.1111/cas.12177. Epub 2013 May 21.

38.

[Prediction of therapeutic efficacy for preoperative chemotherapy].

Ohmura T, Kutomi G, Hirata K.

Nihon Rinsho. 2012 Sep;70 Suppl 7:566-70. Japanese. No abstract available.

PMID:
23350464
39.

[Dye-guided sentinel node biopsy for breast cancer].

Kutomi G, Ohmura T, Suzuki Y, Hirata K.

Nihon Rinsho. 2012 Sep;70 Suppl 7:365-8. Japanese. No abstract available.

PMID:
23350422
40.

[History and future of surgical treatment].

Kutomi G, Ohmura T, Suzuki Y, Hirata K.

Nihon Rinsho. 2012 Sep;70 Suppl 7:13-7. Japanese. No abstract available.

PMID:
23350358
41.

[Human endoplasmic reticulum oxidoreductin 1-like α regulates immune response of cancer cells via modulation of major histocompatibility complex class I expression and oxidation].

Kukita K, Tamura Y, Oku-ya K, Saito K, Kutomi G, Sato N, Hirata K.

Gan To Kagaku Ryoho. 2012 Nov;39(12):1800-2. Japanese.

PMID:
23267891
42.

Immunotherapeutic benefit of α-interferon (IFNα) in survivin2B-derived peptide vaccination for advanced pancreatic cancer patients.

Kameshima H, Tsuruma T, Kutomi G, Shima H, Iwayama Y, Kimura Y, Imamura M, Torigoe T, Takahashi A, Hirohashi Y, Tamura Y, Tsukahara T, Kanaseki T, Sato N, Hirata K.

Cancer Sci. 2013 Jan;104(1):124-9. doi: 10.1111/cas.12046. Epub 2012 Dec 16.

43.

Heat-shock proteins as endogenous ligands building a bridge between innate and adaptive immunity.

Tamura Y, Torigoe T, Kukita K, Saito K, Okuya K, Kutomi G, Hirata K, Sato N.

Immunotherapy. 2012 Aug;4(8):841-52. doi: 10.2217/imt.12.75. Review.

PMID:
22947010
44.

New paradigm for intrinsic function of heat shock proteins as endogenous ligands in inflammation and innate immunity.

Tamura Y, Torigoe T, Kutomi G, Hirata K, Sato N.

Curr Mol Med. 2012 Nov 1;12(9):1198-206. Review.

PMID:
22804242
45.

[Efficacy of vinorelbine in advanced and metastatic breast cancer].

Nishikawa N, Ohmura T, Suzuki Y, Kameshima H, Kutomi G, Hirata K.

Gan To Kagaku Ryoho. 2011 Apr;38(4):577-80. Japanese.

PMID:
21498984
46.

Extracellular heat shock protein 90 plays a role in translocating chaperoned antigen from endosome to proteasome for generating antigenic peptide to be cross-presented by dendritic cells.

Oura J, Tamura Y, Kamiguchi K, Kutomi G, Sahara H, Torigoe T, Himi T, Sato N.

Int Immunol. 2011 Apr;23(4):223-37. doi: 10.1093/intimm/dxq475. Epub 2011 Mar 18.

PMID:
21421737
47.

Tumor-produced secreted form of binding of immunoglobulin protein elicits antigen-specific tumor immunity.

Tamura Y, Hirohashi Y, Kutomi G, Nakanishi K, Kamiguchi K, Torigoe T, Sato N.

J Immunol. 2011 Apr 1;186(7):4325-30. doi: 10.4049/jimmunol.1004048. Epub 2011 Feb 21.

48.

Spatiotemporal regulation of heat shock protein 90-chaperoned self-DNA and CpG-oligodeoxynucleotide for type I IFN induction via targeting to static early endosome.

Okuya K, Tamura Y, Saito K, Kutomi G, Torigoe T, Hirata K, Sato N.

J Immunol. 2010 Jun 15;184(12):7092-9. doi: 10.4049/jimmunol.1000490. Epub 2010 May 14.

49.

Targeting to static endosome is required for efficient cross-presentation of endoplasmic reticulum-resident oxygen-regulated protein 150-peptide complexes.

Kutomi G, Tamura Y, Okuya K, Yamamoto T, Hirohashi Y, Kamiguchi K, Oura J, Saito K, Torigoe T, Ogawa S, Hirata K, Sato N.

J Immunol. 2009 Nov 1;183(9):5861-9. doi: 10.4049/jimmunol.0803768. Epub 2009 Oct 7.

50.

Efficient cross-presentation by heat shock protein 90-peptide complex-loaded dendritic cells via an endosomal pathway.

Kurotaki T, Tamura Y, Ueda G, Oura J, Kutomi G, Hirohashi Y, Sahara H, Torigoe T, Hiratsuka H, Sunakawa H, Hirata K, Sato N.

J Immunol. 2007 Aug 1;179(3):1803-13.

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