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Items: 1 to 50 of 104

1.

Antibacterial activity of new structural class of semisynthetic molecule, triphenyl-phosphonium conjugated diarylheptanoid.

Kumari S, Jayakumar S, Gupta GD, Bihani SC, Sharma D, Kutala VK, Sandur SK, Kumar V.

Free Radic Biol Med. 2019 Aug 6;143:140-145. doi: 10.1016/j.freeradbiomed.2019.08.003. [Epub ahead of print]

PMID:
31398499
2.

Dual Effect of IL-6 -174 G/C Polymorphism and Promoter Methylation in the Risk of Coronary Artery Disease Among South Indians.

Indumathi B, Katkam SK, Krishna LSR, Kutala VK.

Indian J Clin Biochem. 2019 Apr;34(2):180-187. doi: 10.1007/s12291-018-0740-3. Epub 2018 Feb 21.

PMID:
31092991
3.

Recipient ABCB1, donor and recipient CYP3A5 genotypes influence tacrolimus pharmacokinetics in liver transplant cases.

Naushad SM, Pavani A, Rupasree Y, Hussain T, Alrokayan SA, Kutala VK.

Pharmacol Rep. 2019 Jun;71(3):385-392. doi: 10.1016/j.pharep.2019.01.006. Epub 2019 Jan 11.

PMID:
31003147
4.

Classification and regression tree-based prediction of 6-mercaptopurine-induced leucopenia grades in children with acute lymphoblastic leukemia.

Naushad SM, Dorababu P, Rupasree Y, Pavani A, Raghunadharao D, Hussain T, Alrokayan SA, Kutala VK.

Cancer Chemother Pharmacol. 2019 May;83(5):875-880. doi: 10.1007/s00280-019-03803-8. Epub 2019 Feb 26.

PMID:
30806759
5.

Impact of pharmacogenetics on statin-induced myopathy in South-Indian subjects.

Ramakumari N, Indumathi B, Katkam SK, Kutala VK.

Indian Heart J. 2018 Dec;70 Suppl 3:S120-S125. doi: 10.1016/j.ihj.2018.07.009. Epub 2018 Aug 10.

6.

Effect of CYP4F2, VKORC1, and CYP2C9 in Influencing Coumarin Dose: A Single-Patient Data Meta-Analysis in More Than 15,000 Individuals.

Danese E, Raimondi S, Montagnana M, Tagetti A, Langaee T, Borgiani P, Ciccacci C, Carcas AJ, Borobia AM, Tong HY, Dávila-Fajardo C, Rodrigues Botton M, Bourgeois S, Deloukas P, Caldwell MD, Burmester JK, Berg RL, Cavallari LH, Drozda K, Huang M, Zhao LZ, Cen HJ, Gonzalez-Conejero R, Roldan V, Nakamura Y, Mushiroda T, Gong IY, Kim RB, Hirai K, Itoh K, Isaza C, Beltrán L, Jiménez-Varo E, Cañadas-Garre M, Giontella A, Kringen MK, Haug KBF, Gwak HS, Lee KE, Minuz P, Lee MTM, Lubitz SA, Scott S, Mazzaccara C, Sacchetti L, Genç E, Özer M, Pathare A, Krishnamoorthy R, Paldi A, Siguret V, Loriot MA, Kutala VK, Suarez-Kurtz G, Perini J, Denny JC, Ramirez AH, Mittal B, Rathore SS, Sagreiya H, Altman R, Shahin MHA, Khalifa SI, Limdi NA, Rivers C, Shendre A, Dillon C, Suriapranata IM, Zhou HH, Tan SL, Tatarunas V, Lesauskaite V, Zhang Y, Maitland-van der Zee AH, Verhoef TI, de Boer A, Taljaard M, Zambon CF, Pengo V, Zhang JE, Pirmohamed M, Johnson JA, Fava C.

Clin Pharmacol Ther. 2019 Jun;105(6):1477-1491. doi: 10.1002/cpt.1323. Epub 2019 Feb 17.

PMID:
30506689
7.

Machine learning algorithm-based risk prediction model of coronary artery disease.

Naushad SM, Hussain T, Indumathi B, Samreen K, Alrokayan SA, Kutala VK.

Mol Biol Rep. 2018 Oct;45(5):901-910. doi: 10.1007/s11033-018-4236-2. Epub 2018 Jul 11.

PMID:
29995270
8.

Meta-analysis of genetic polymorphisms in xenobiotic metabolizing enzymes and their association with breast cancer risk.

Hussain T, Alrokayan S, Upasna U, Pavithrakumari M, Jayapriya J, Kutala VK, Naushad SM.

J Genet. 2018 Jun;97(2):523-537.

9.

Artificial neural network model for predicting the bioavailability of tacrolimus in patients with renal transplantation.

Thishya K, Vattam KK, Naushad SM, Raju SB, Kutala VK.

PLoS One. 2018 Apr 5;13(4):e0191921. doi: 10.1371/journal.pone.0191921. eCollection 2018.

10.

Impact of eNOS 27-bp VNTR (4b/a) gene polymorphism with the risk of Systemic Lupus Erythematosus in south Indian subjects.

Katkam SK, Indumathi B, Tasneem FSD, Rajasekhar L, Kutala VK.

Gene. 2018 Jun 5;658:105-112. doi: 10.1016/j.gene.2018.03.021. Epub 2018 Mar 8.

PMID:
29524578
11.

The influence of functional polymorphic positions of HLA-DRβ1 molecules on risk for South Indian systemic lupus erythematosus patients.

Katkam SK, Rajasekhar L, Kutala VK.

Lupus. 2018 May;27(6):991-1000. doi: 10.1177/0961203318759200. Epub 2018 Feb 13.

PMID:
29439646
12.

Neuro-fuzzy model of homocysteine metabolism.

Naushad SM, Rama Devi AR, Nivetha S, Lakshmitha G, Stanley AB, Hussain T, Kutala VK.

J Genet. 2017 Dec;96(6):919-926.

13.

Mitochondrial targeted curcumin exhibits anticancer effects through disruption of mitochondrial redox and modulation of TrxR2 activity.

Jayakumar S, Patwardhan RS, Pal D, Singh B, Sharma D, Kutala VK, Sandur SK.

Free Radic Biol Med. 2017 Dec;113:530-538. doi: 10.1016/j.freeradbiomed.2017.10.378. Epub 2017 Nov 5.

PMID:
29080841
14.

Epistatic interactions among CYP2C19*2, CYP3A4 and GSTP1 on the cyclophosphamide therapy in lupus nephritis patients.

Kumaraswami K, Katkam SK, Aggarwal A, Sharma A, Manthri R, Kutala VK, Rajasekhar L.

Pharmacogenomics. 2017 Oct;18(15):1401-1411. doi: 10.2217/pgs-2017-0069. Epub 2017 Oct 4.

PMID:
28976264
15.

Association of IL -6 -174 G>C polymorphism with the risk of SLE among south Indians: evidence from case-control study and meta-analysis.

Katkam SK, Rajasekhar L, Kumaraswami K, Kutala VK.

Lupus. 2017 Dec;26(14):1491-1501. doi: 10.1177/0961203317711010. Epub 2017 May 22. Review.

PMID:
28530463
16.

Association of GSTT1 and GSTM1 polymorphisms in South Indian Epilepsy Patients.

Prabha TS, Kumaraswami K, Kutala VK.

Indian J Exp Biol. 2016 Nov;54(11):783-7.

PMID:
30179425
17.

c.*84G>A Mutation in CETP Is Associated with Coronary Artery Disease in South Indians.

Ganesan M, Nizamuddin S, Katkam SK, Kumaraswami K, Hosad UK, Lobo LL, Kutala VK, Thangaraj K.

PLoS One. 2016 Oct 21;11(10):e0164151. doi: 10.1371/journal.pone.0164151. eCollection 2016.

18.

Association of serum interleukin-6, interleukin-8, and Acute Physiology and Chronic Health Evaluation II score with clinical outcome in patients with acute respiratory distress syndrome.

Swaroopa D, Bhaskar K, Mahathi T, Katkam S, Raju YS, Chandra N, Kutala VK.

Indian J Crit Care Med. 2016 Sep;20(9):518-25. doi: 10.4103/0972-5229.190369.

19.

Endothelial Dysfunction in Type 2 Diabetes Mellitus.

Dhananjayan R, Koundinya KS, Malati T, Kutala VK.

Indian J Clin Biochem. 2016 Oct;31(4):372-9. doi: 10.1007/s12291-015-0516-y. Epub 2015 Sep 29. Review.

20.

Population-level diversity in the association of genetic polymorphisms of one-carbon metabolism with breast cancer risk.

Naushad SM, Divya C, Janaki Ramaiah M, Hussain T, Alrokayan SA, Kutala VK.

J Community Genet. 2016 Oct;7(4):279-290. Epub 2016 Aug 19.

21.

Development of neuro-fuzzy model to explore gene-nutrient interactions modulating warfarin dose requirement.

Pavani A, Naushad SM, Lakshmitha G, Nivetha S, Stanley BA, Malempati AR, Kutala VK.

Pharmacogenomics. 2016 Aug;17(12):1315-25. doi: 10.2217/pgs-2016-0058. Epub 2016 Jul 27.

PMID:
27462768
22.

In silico approaches to identify the potential inhibitors of glutamate carboxypeptidase II (GCPII) for neuroprotection.

Naushad SM, Janaki Ramaiah M, Stanley BA, Prasanna Lakshmi S, Vishnu Priya J, Hussain T, Alrokayan SA, Kutala VK.

J Theor Biol. 2016 Oct 7;406:137-42. doi: 10.1016/j.jtbi.2016.07.016. Epub 2016 Jul 16.

PMID:
27430729
23.

Assessment of Oxidative Stress Markers and Carotid Artery Intima-Media Thickness in Elderly Patients Without and with Coronary Artery Disease.

Madisetty MK, Kumaraswami K, Katkam S, Saumya K, Satyanarayana Raju Y, Chandra N, Jyotsna M, Patnaik S, Kutala VK.

Indian J Clin Biochem. 2016 Jul;31(3):278-85. doi: 10.1007/s12291-015-0530-0. Epub 2015 Oct 6.

24.

Artificial neural network-based exploration of gene-nutrient interactions in folate and xenobiotic metabolic pathways that modulate susceptibility to breast cancer.

Naushad SM, Janaki Ramaiah M, Pavithrakumari M, Jayapriya J, Hussain T, Alrokayan SA, Gottumukkala SR, Digumarti R, Kutala VK.

Gene. 2016 Apr 15;580(2):159-168. doi: 10.1016/j.gene.2016.01.023. Epub 2016 Jan 16.

PMID:
26784656
25.

Application of Various Statistical Models to Explore Gene-Gene Interactions in Folate, Xenobiotic, Toll-Like Receptor and STAT4 Pathways that Modulate Susceptibility to Systemic Lupus Erythematosus.

Rupasree Y, Naushad SM, Varshaa R, Mahalakshmi GS, Kumaraswami K, Rajasekhar L, Kutala VK.

Mol Diagn Ther. 2016 Feb;20(1):83-95. doi: 10.1007/s40291-015-0181-0.

PMID:
26689915
26.

Association of estrogen receptor 1 (ESR1) haplotypes with risk for systemic lupus erythematosus among South Indians.

Rupasree Y, Naushad SM, Rajasekhar L, Uma A, Kutala VK.

Indian J Exp Biol. 2015 Nov;53(11):714-8.

PMID:
26669013
27.

Artificial neural network-based pharmacogenomic algorithm for warfarin dose optimization.

Pavani A, Naushad SM, Kumar RM, Srinath M, Malempati AR, Kutala VK.

Pharmacogenomics. 2016;17(2):121-31. doi: 10.2217/pgs.15.161. Epub 2015 Dec 15.

PMID:
26666467
28.

Association of CTLA4 exon-1 polymorphism with the tumor necrosis factor-α in the risk of systemic lupus erythematosus among South Indians.

Katkam SK, Kumaraswami K, Rupasree Y, Thishya K, Rajasekhar L, Kutala VK.

Hum Immunol. 2016 Feb;77(2):158-64. doi: 10.1016/j.humimm.2015.11.002. Epub 2015 Nov 12.

PMID:
26582004
29.
30.

Clinical utility of genetic variants of glutamate carboxypeptidase II in predicting breast cancer and prostate cancer risk.

Naushad SM, Shree Divyya P, Janaki Ramaiah M, Alex Stanley B, Prasanna Lakshmi S, Vishnupriya J, Kutala VK.

Cancer Genet. 2015 Nov;208(11):552-8. doi: 10.1016/j.cancergen.2015.09.001. Epub 2015 Sep 8.

PMID:
26471812
31.

Comparative analysis of four disease prediction models of Parkinson's disease.

Kumudini N, Naushad SM, Alex Stanley B, Niveditha M, Sharmila G, Kumaraswami K, Borghain R, Mridula R, Kutala VK.

Mol Cell Biochem. 2016 Jan;411(1-2):127-34. doi: 10.1007/s11010-015-2574-0. Epub 2015 Oct 5.

PMID:
26438087
32.

Association of Aberrations in One Carbon Metabolism with Intimal Medial Thickening in Patients with Type 2 Diabetes Mellitus.

Dhananjayan R, Malati T, Rupasree Y, Kutala VK.

Indian J Clin Biochem. 2015 Jul;30(3):263-70. doi: 10.1007/s12291-014-0458-9. Epub 2014 Jul 26.

33.

Mechanistic insights into the effect of CYP2C9*2 and CYP2C9*3 variants on the 7-hydroxylation of warfarin.

Pavani A, Naushad SM, Stanley BA, Kamakshi RG, Abinaya K, Amaresh Rao M, Uma A, Kutala VK.

Pharmacogenomics. 2015;16(4):393-400. doi: 10.2217/pgs.14.185.

PMID:
25823787
34.

Multifactor dimensionality reduction analysis to elucidate the cross-talk between one-carbon and xenobiotic metabolic pathways in multi-disease models.

Naushad SM, Vijayalakshmi SV, Rupasree Y, Kumudini N, Sowganthika S, Naidu JV, Ramaiah MJ, Rao DN, Kutala VK.

Mol Biol Rep. 2015 Jul;42(7):1211-24. doi: 10.1007/s11033-015-3856-z. Epub 2015 Feb 4.

PMID:
25648260
35.

Molecular mechanism of interaction of mitocurcumin-1 with Akt1 and STAT3: an in silico approach.

Vasagiri N, Kutala VK.

Indian J Biochem Biophys. 2014 Aug;51(4):308-13.

PMID:
25296502
36.

Association of TLR4 (D299G, T399I), TLR9 -1486T>C, TIRAP S180L and TNF-α promoter (-1031, -863, -857) polymorphisms with risk for systemic lupus erythematosus among South Indians.

Rupasree Y, Naushad SM, Rajasekhar L, Uma A, Kutala VK.

Lupus. 2015 Jan;24(1):50-7. doi: 10.1177/0961203314549792. Epub 2014 Sep 2.

PMID:
25182168
37.

Structure, function, and epigenetic regulation of BNIP3: a pathophysiological relevance.

Vasagiri N, Kutala VK.

Mol Biol Rep. 2014 Nov;41(11):7705-14. doi: 10.1007/s11033-014-3664-x. Epub 2014 Aug 6. Review.

PMID:
25096512
38.

Methodological issues in the development of a pharmacogenomic algorithm for warfarin dosing: comparison of two regression approaches.

Pavani A, Naushad SM, Uma A, Kutala VK.

Pharmacogenomics. 2014 Jun;15(8):1125-32. doi: 10.2217/pgs.14.59.

PMID:
25084205
39.

Association of Parkinson's disease with altered serum levels of lead and transition metals among South Indian subjects.

Kumudini N, Uma A, Devi YP, Naushad SM, Mridula R, Borgohain R, Kutala VK.

Indian J Biochem Biophys. 2014 Apr;51(2):121-6.

PMID:
24980015
40.

Association of genetic variants of xenobiotic metabolic pathway with systemic lupus erythematosus.

Rupasree Y, Naushad SM, Rajasekhar L, Kutala VK.

Indian J Biochem Biophys. 2013 Oct;50(5):447-52.

PMID:
24772967
41.

Impact of COMT H108L, MAOB int 13 A>G and DRD2 haplotype on the susceptibility to Parkinson's disease in South Indian subjects.

Kumudini N, Umai A, Devi YP, Naushad SM, Mridula R, Borgohain R, Kutala VK.

Indian J Biochem Biophys. 2013 Oct;50(5):436-41.

PMID:
24772965
42.

Association of seven functional polymorphisms of one-carbon metabolic pathway with total plasma homocysteine levels and susceptibility to Parkinson's disease among South Indians.

Kumudini N, Uma A, Naushad SM, Mridula R, Borgohain R, Kutala VK.

Neurosci Lett. 2014 May 7;568:1-5. doi: 10.1016/j.neulet.2014.03.044. Epub 2014 Mar 28.

PMID:
24686188
43.

Molecular insights into the association of obesity with breast cancer risk: relevance to xenobiotic metabolism and CpG island methylation of tumor suppressor genes.

Naushad SM, Hussain T, Al-Attas OS, Prayaga A, Digumarti RR, Gottumukkala SR, Kutala VK.

Mol Cell Biochem. 2014 Jul;392(1-2):273-80. doi: 10.1007/s11010-014-2037-z. Epub 2014 Mar 28.

PMID:
24676543
44.

Mitochondrial-targeted curcuminoids: a strategy to enhance bioavailability and anticancer efficacy of curcumin.

Reddy CA, Somepalli V, Golakoti T, Kanugula AK, Karnewar S, Rajendiran K, Vasagiri N, Prabhakar S, Kuppusamy P, Kotamraju S, Kutala VK.

PLoS One. 2014 Mar 12;9(3):e89351. doi: 10.1371/journal.pone.0089351. eCollection 2014.

45.

Sexual dimorphism in xenobiotic genetic variants-mediated risk for Parkinson's disease.

Kumudini N, Uma A, Naushad SM, Mridula R, Borgohain R, Kutala VK.

Neurol Sci. 2014 Jun;35(6):897-903. doi: 10.1007/s10072-013-1622-3. Epub 2014 Jan 4.

PMID:
24389856
46.

Epigenetic modulation of RFC1, MHC2TA and HLA-DR in systemic lupus erythematosus: association with serological markers and six functional polymorphisms of one-carbon metabolic pathway.

Rupasree Y, Naushad SM, Rajasekhar L, Kutala VK.

Gene. 2014 Feb 15;536(1):45-52. doi: 10.1016/j.gene.2013.11.094. Epub 2013 Dec 12.

PMID:
24333266
47.

Special issue on oxidative stress in health and disease.

Sharma HS, Kutala VK, Kuppusamy P.

Cell Biochem Biophys. 2013 Nov;67(2):215-8. doi: 10.1007/s12013-013-9774-6. No abstract available.

PMID:
24142440
48.

GCPII modulates oxidative stress and prostate cancer susceptibility through changes in methylation of RASSF1, BNIP3, GSTP1 and Ec-SOD.

Divyya S, Naushad SM, Murthy PV, Reddy ChR, Kutala VK.

Mol Biol Rep. 2013 Oct;40(10):5541-50. doi: 10.1007/s11033-013-2655-7. Epub 2013 Aug 24.

PMID:
23979608
49.

Impact of hyperhomocysteinemia on breast cancer initiation and progression: epigenetic perspective.

Naushad SM, Reddy CA, Kumaraswami K, Divyya S, Kotamraju S, Gottumukkala SR, Digumarti RR, Kutala VK.

Cell Biochem Biophys. 2014 Mar;68(2):397-406. doi: 10.1007/s12013-013-9720-7.

PMID:
23934182
50.

Association of family history of type 2 diabetes mellitus with markers of endothelial dysfunction in South Indian population.

Dhananjayan R, Malati T, Brindha G, Kutala VK.

Indian J Biochem Biophys. 2013 Apr;50(2):93-8.

PMID:
23720882

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