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Variability in alkaloid and phenolic content vis-a-vis antigout potential among the natural population of Gloriosa superba (L.) collected from Central India.

Misra A, Srivastava S, Shukla PK, Kumar M, Khalid M, Kushwaha P, Agrawal PK.

Nat Prod Res. 2019 Oct 14:1-5. doi: 10.1080/14786419.2019.1675069. [Epub ahead of print]


Emerging Role of Migration and Invasion Enhancer 1 (MIEN1) in Cancer Progression and Metastasis.

Kushwaha PP, Gupta S, Singh AK, Kumar S.

Front Oncol. 2019 Sep 4;9:868. doi: 10.3389/fonc.2019.00868. eCollection 2019. Review.


Elevated FGF23 in a patient with hypophosphatemic osteomalacia associated with neurofibromatosis type 1.

Sahoo SK, Kushwaha P, Bharti N, Khedgikar V, Trivedi R, Agrawal V, Ahmad N, Zaidi G, Pal L, Ito N, Bhatia E.

Bone. 2019 Aug 30;129:115055. doi: 10.1016/j.bone.2019.115055. [Epub ahead of print]


Bulbine frutescens phytochemical inhibits notch signaling pathway and induces apoptosis in triple negative and luminal breast cancer cells.

Kushwaha PP, Vardhan PS, Kapewangolo P, Shuaib M, Prajapati SK, Singh AK, Kumar S.

Life Sci. 2019 Oct 1;234:116783. doi: 10.1016/j.lfs.2019.116783. Epub 2019 Aug 21.


Estrogen receptor activation in response to Azadirachtin A stimulates osteoblast differentiation and bone formation in mice.

Kushwaha P, Ahmad N, Dhar YV, Verma A, Haldar S, Mulani FA, Trivedi PK, Mishra PR, Thulasiram HV, Trivedi R.

J Cell Physiol. 2019 Dec;234(12):23719-23735. doi: 10.1002/jcp.28940. Epub 2019 Jun 21.


Synthesis, Biological Evaluation, Structure-Activity Relationship, and Mechanism of Action Studies of Quinoline-Metronidazole Derivatives Against Experimental Visceral Leishmaniasis.

Upadhyay A, Chandrakar P, Gupta S, Parmar N, Singh SK, Rashid M, Kushwaha P, Wahajuddin M, Sashidhara KV, Kar S.

J Med Chem. 2019 Jun 13;62(11):5655-5671. doi: 10.1021/acs.jmedchem.9b00628. Epub 2019 May 24.


Lrp4 expression by adipocytes and osteoblasts differentially impacts sclerostin's endocrine effects on body composition and glucose metabolism.

Kim SP, Da H, Li Z, Kushwaha P, Beil C, Mei L, Xiong WC, Wolfgang MJ, Clemens TL, Riddle RC.

J Biol Chem. 2019 Apr 26;294(17):6899-6911. doi: 10.1074/jbc.RA118.006769. Epub 2019 Mar 6.


Implementation of a practical and effective pilot intervention against transmission of Taenia solium by pigs in the Banke district of Nepal.

Poudel I, Sah K, Subedi S, Kumar Singh D, Kushwaha P, Colston A, Gauci CG, Donadeu M, Lightowlers MW.

PLoS Negl Trop Dis. 2019 Feb 25;13(2):e0006838. doi: 10.1371/journal.pntd.0006838. eCollection 2019 Feb.


MicroRNA-672-5p Identified during Weaning Reverses Osteopenia and Sarcopenia in Ovariectomized Mice.

Ahmad N, Kushwaha P, Karvande A, Tripathi AK, Kothari P, Adhikary S, Khedgikar V, Mishra VK, Trivedi R.

Mol Ther Nucleic Acids. 2019 Mar 1;14:536-549. doi: 10.1016/j.omtn.2019.01.002. Epub 2019 Jan 10.


Itinerant ferromagnetism of the Pd-terminated polar surface of PdCoO2.

Mazzola F, Sunko V, Khim S, Rosner H, Kushwaha P, Clark OJ, Bawden L, Marković I, Kim TK, Hoesch M, Mackenzie AP, King PDC.

Proc Natl Acad Sci U S A. 2018 Dec 18;115(51):12956-12960. doi: 10.1073/pnas.1811873115. Epub 2018 Dec 4.


Synthesis, biological evaluation and molecular dynamic simulations of novel Benzofuran-tetrazole derivatives as potential agents against Alzheimer's disease.

Kushwaha P, Fatima S, Upadhyay A, Gupta S, Bhagwati S, Baghel T, Siddiqi MI, Nazir A, Sashidhara KV.

Bioorg Med Chem Lett. 2019 Jan 1;29(1):66-72. doi: 10.1016/j.bmcl.2018.11.005. Epub 2018 Nov 8.


In-house chemical library repurposing: A case example for Pseudomonas aeruginosa antibiofilm activity and quorum sensing inhibition.

Ravithej Singh L, Tripathi VC, Raj S, Kumar A, Gupta S, Horam S, Upadhyay A, Kushwaha P, Arockiaraj J, Sashidhara KV, Pasupuleti M.

Drug Dev Res. 2018 Dec;79(8):383-390. doi: 10.1002/ddr.21458. Epub 2018 Oct 6.


Glucose dependent miR-451a expression contributes to parathyroid hormone mediated osteoblast differentiation.

Karvande A, Kushwaha P, Ahmad N, Adhikary S, Kothari P, Tripathi AK, Khedgikar V, Trivedi R.

Bone. 2018 Dec;117:98-115. doi: 10.1016/j.bone.2018.09.007. Epub 2018 Sep 13.


Discovery of a tetrazolyl β-carboline with in vitro and in vivo osteoprotective activity under estrogen-deficient conditions.

Karvande A, Khan S, Khan I, Singh D, Khedgikar V, Kushwaha P, Ahmad N, Kothari P, Dhasmana A, Kant R, Trivedi R, Chauhan PMS.

Medchemcomm. 2018 Jun 12;9(7):1213-1225. doi: 10.1039/c8md00109j. eCollection 2018 Jul 1.


Synthesis and study of benzofuran-pyran analogs as BMP-2 targeted osteogenic agents.

Kushwaha P, Tripathi AK, Gupta S, Kothari P, Upadhyay A, Ahmad N, Sharma T, Siddiqi MI, Trivedi R, Sashidhara KV.

Eur J Med Chem. 2018 Aug 5;156:103-117. doi: 10.1016/j.ejmech.2018.06.062. Epub 2018 Jun 28.


Synthesis and evaluation of novel triazolyl quinoline derivatives as potential antileishmanial agents.

Upadhyay A, Kushwaha P, Gupta S, Dodda RP, Ramalingam K, Kant R, Goyal N, Sashidhara KV.

Eur J Med Chem. 2018 Jun 25;154:172-181. doi: 10.1016/j.ejmech.2018.05.014. Epub 2018 May 12.


Comparative safety evaluation of riot control agents of synthetic and natural origin.

Satpute RM, Kushwaha PK, Nagar DP, Rao PVL.

Inhal Toxicol. 2018 Feb;30(2):89-97. doi: 10.1080/08958378.2018.1451575.


Combinatorial drug delivery strategy employing nano-curcumin and nano-MiADMSA for the treatment of arsenic intoxication in mouse.

Kushwaha P, Yadav A, Samim M, Flora SJS.

Chem Biol Interact. 2018 Apr 25;286:78-87. doi: 10.1016/j.cbi.2018.03.006. Epub 2018 Mar 13.


Chloracne in a Farming Family.

Kushwaha P, Kumar H, Kulkarni S, Ghorpade A.

Skinmed. 2017 Dec 1;15(6):485-488. eCollection 2017.


Assessing the impact of a novel strategy for delivering animal health interventions to smallholder farmers.

Bessell PR, Kushwaha P, Mosha R, Woolley R, Al-Riyami L, Gammon N.

Prev Vet Med. 2017 Nov 1;147:108-116. doi: 10.1016/j.prevetmed.2017.08.022. Epub 2017 Aug 31.


Sclerostin influences body composition by regulating catabolic and anabolic metabolism in adipocytes.

Kim SP, Frey JL, Li Z, Kushwaha P, Zoch ML, Tomlinson RE, Da H, Aja S, Noh HL, Kim JK, Hussain MA, Thorek DLJ, Wolfgang MJ, Riddle RC.

Proc Natl Acad Sci U S A. 2017 Dec 26;114(52):E11238-E11247. doi: 10.1073/pnas.1707876115. Epub 2017 Dec 11.


Synthesis and bio-evaluation of indole-chalcone based benzopyrans as promising antiligase and antiproliferative agents.

Gupta S, Maurya P, Upadhyay A, Kushwaha P, Krishna S, Siddiqi MI, Sashidhara KV, Banerjee D.

Eur J Med Chem. 2018 Jan 1;143:1981-1996. doi: 10.1016/j.ejmech.2017.11.015. Epub 2017 Nov 7.


High-performance Thin-layer Chromatographic-densitometric Quantification and Recovery of Bioactive Compounds for Identification of Elite Chemotypes of Gloriosa superba L. Collected from Sikkim Himalayas (India).

Misra A, Shukla PK, Kumar B, Chand J, Kushwaha P, Khalid M, Singh Rawat AK, Srivastava S.

Pharmacogn Mag. 2017 Oct;13(Suppl 3):S700-S705. doi: 10.4103/pm.pm_576_16. Epub 2017 Oct 11.


Maximal Rashba-like spin splitting via kinetic-energy-coupled inversion-symmetry breaking.

Sunko V, Rosner H, Kushwaha P, Khim S, Mazzola F, Bawden L, Clark OJ, Riley JM, Kasinathan D, Haverkort MW, Kim TK, Hoesch M, Fujii J, Vobornik I, Mackenzie AP, King PDC.

Nature. 2017 Sep 27;549(7673):492-496. doi: 10.1038/nature23898.


Fatty acid metabolism by the osteoblast.

Kushwaha P, Wolfgang MJ, Riddle RC.

Bone. 2018 Oct;115:8-14. doi: 10.1016/j.bone.2017.08.024. Epub 2017 Aug 31. Review.


Fatty acid oxidation by the osteoblast is required for normal bone acquisition in a sex- and diet-dependent manner.

Kim SP, Li Z, Zoch ML, Frey JL, Bowman CE, Kushwaha P, Ryan KA, Goh BC, Scafidi S, Pickett JE, Faugere MC, Kershaw EE, Thorek DLJ, Clemens TL, Wolfgang MJ, Riddle RC.

JCI Insight. 2017 Aug 17;2(16). pii: 92704. doi: 10.1172/jci.insight.92704. eCollection 2017 Aug 17.


A hyperendemic focus of Taenia solium transmission in the Banke District of Nepal.

Sah K, Poudel I, Subedi S, Singh DK, Cocker J, Kushwaha P, Colston A, Donadeu M, Lightowlers MW.

Acta Trop. 2017 Dec;176:78-82. doi: 10.1016/j.actatropica.2017.07.022. Epub 2017 Jul 21.


Noninvasive assessment of cutaneous alterations in mice exposed to whole body gamma irradiation using optical imaging techniques.

Sharma P, Sahu K, Kushwaha PK, Kumar S, Swami MK, Kumawat J, Patel HS, Kher S, Sahani PK, Haridas G, Gupta PK.

Lasers Med Sci. 2017 Sep;32(7):1535-1544. doi: 10.1007/s10103-017-2276-9. Epub 2017 Jul 11.


Heartwood extract from Dalbergia sissoo promotes fracture healing and its application in ovariectomy-induced osteoporotic rats.

Karvande A, Khedgikar V, Kushwaha P, Ahmad N, Kothari P, Verma A, Kumar P, Nagar GK, Mishra PR, Maurya R, Trivedi R.

J Pharm Pharmacol. 2017 Oct;69(10):1381-1397. doi: 10.1111/jphp.12764. Epub 2017 Jun 30.


Detrimental effects of atherogenic and high fat diet on bone and aortic calcification rescued by an isoflavonoid Caviunin β-d-glucopyranoside.

Choudhary D, Adhikary S, Gautam J, Maurya P, Ahmad N, Kushwaha P, Khan MP, Kumar A, Barthwal M, Maurya R, Trivedi R.

Biomed Pharmacother. 2017 Aug;92:757-771. doi: 10.1016/j.biopha.2017.05.120. Epub 2017 Jun 4.


The diacylglycerol acyltransferase Rv3371 of Mycobacterium tuberculosis is required for growth arrest and involved in stress-induced cell wall alterations.

Rastogi S, Singh AK, Chandra G, Kushwaha P, Pant G, Singh K, Mitra K, Sashidhara KV, Krishnan MY.

Tuberculosis (Edinb). 2017 May;104:8-19. doi: 10.1016/ Epub 2017 Feb 14.


Formononetin, an isoflavone, activates AMP-activated protein kinase/β-catenin signalling to inhibit adipogenesis and rescues C57BL/6 mice from high-fat diet-induced obesity and bone loss.

Gautam J, Khedgikar V, Kushwaha P, Choudhary D, Nagar GK, Dev K, Dixit P, Singh D, Maurya R, Trivedi R.

Br J Nutr. 2017 Mar;117(5):645-661. doi: 10.1017/S0007114517000149. Epub 2017 Apr 3.


Design and synthesis of dalbergin analogues and evaluation of anti-osteoporotic activity.

Kumar P, Kushwaha P, Ahmad N, Maurya SW, Dev K, Khedgikar V, Siddiqui IR, Trivedi R, Maurya R.

Bioorg Med Chem Lett. 2017 Apr 15;27(8):1765-1775. doi: 10.1016/j.bmcl.2017.02.062. Epub 2017 Feb 27.


Evaluation of anti-osteoporotic activity of butanolic fraction from Passiflora foetida in ovariectomy-induced bone loss in mice.

Ahmad N, Chillara R, Kushwaha P, Khedgikar V, Karvande A, Choudhary D, Adhikary S, Maurya R, Trivedi R.

Biomed Pharmacother. 2017 Apr;88:804-813. doi: 10.1016/j.biopha.2017.01.100. Epub 2017 Feb 1.


An Updated Review on the Phytochemistry, Pharmacology, and Clinical Trials of Salacia oblonga.

Kushwaha PS, Singh AK, Keshari AK, Maity S, Saha S.

Pharmacogn Rev. 2016 Jul-Dec;10(20):109-114. doi: 10.4103/0973-7847.194046.


Ethanolic extract of Dalbergia sissoo promotes rapid regeneration of cortical bone in drill-hole defect model of rat.

Khedgikar V, Kushwaha P, Ahmad N, Gautam J, Kumar P, Maurya R, Trivedi R.

Biomed Pharmacother. 2017 Feb;86:16-22. doi: 10.1016/j.biopha.2016.11.140. Epub 2016 Dec 6.


Development of Leishmania donovani stably expressing DsRed for flow cytometry-based drug screening using chalcone thiazolyl-hydrazone as a new antileishmanial target.

Jaiswal AK, Rao KB, Kushwaha P, Rawat K, Modukuri RK, Khare P, Joshi S, Mishra S, Rai A, Sashidhara KV, Dube A.

Int J Antimicrob Agents. 2016 Dec;48(6):695-702. doi: 10.1016/j.ijantimicag.2016.09.018. Epub 2016 Nov 2.


Fast and long acting neoflavonoids dalbergin isolated from Dalbergia sissoo heartwood is osteoprotective in ovariectomized model of osteoporosis: Osteoprotective effect of Dalbergin.

Choudhary D, Kushwaha P, Gautam J, Kumar P, Verma A, Kumar A, Maurya SW, Siddiqui IR, Mishra PR, Maurya R, Trivedi R.

Biomed Pharmacother. 2016 Oct;83:942-957. doi: 10.1016/j.biopha.2016.08.010. Epub 2016 Aug 11.


Geminin a multi task protein involved in cancer pathophysiology and developmental process: A review.

Kushwaha PP, Rapalli KC, Kumar S.

Biochimie. 2016 Dec;131:115-127. doi: 10.1016/j.biochi.2016.09.022. Epub 2016 Oct 1. Review.


Azadirachta indica triterpenoids promote osteoblast differentiation and mineralization in vitro and in vivo.

Kushwaha P, Khedgikar V, Haldar S, Gautam J, Mulani FA, Thulasiram HV, Trivedi R.

Bioorg Med Chem Lett. 2016 Aug 1;26(15):3719-24. doi: 10.1016/j.bmcl.2016.05.076. Epub 2016 May 27.


A neoflavonoid dalsissooal isolated from heartwood of Dalbergia sissoo Roxb. has bone forming effects in mice model for osteoporosis.

Kushwaha P, Khedgikar V, Ahmad N, Karvande A, Gautam J, Kumar P, Maurya R, Trivedi R.

Eur J Pharmacol. 2016 Oct 5;788:65-74. doi: 10.1016/j.ejphar.2016.06.003. Epub 2016 Jun 15.


An isoflavone cladrin prevents high-fat diet-induced bone loss and inhibits the expression of adipogenic gene regulators in 3T3-L1 adipocyte.

Gautam J, Khedgikar V, Choudhary D, Kushwaha P, Dixit P, Singh D, Maurya R, Trivedi R.

J Pharm Pharmacol. 2016 Aug;68(8):1051-63. doi: 10.1111/jphp.12562. Epub 2016 Jun 5.


ARPES view on surface and bulk hybridization phenomena in the antiferromagnetic Kondo lattice CeRh2Si2.

Patil S, Generalov A, Güttler M, Kushwaha P, Chikina A, Kummer K, Rödel TC, Santander-Syro AF, Caroca-Canales N, Geibel C, Danzenbächer S, Kucherenko Y, Laubschat C, Allen JW, Vyalikh DV.

Nat Commun. 2016 Mar 18;7:11029. doi: 10.1038/ncomms11029.


Kaempferol targets Krt-14 and induces cytoskeletal mineralization in osteoblasts: A mechanistic approach.

Khedgikar V, Kushwaha P, Gautam J, Sharma S, Verma A, Choudhary D, Mishra PR, Trivedi R.

Life Sci. 2016 Apr 15;151:207-217. doi: 10.1016/j.lfs.2016.03.009. Epub 2016 Mar 5.


Evidence for hydrodynamic electron flow in PdCoO₂.

Moll PJ, Kushwaha P, Nandi N, Schmidt B, Mackenzie AP.

Science. 2016 Mar 4;351(6277):1061-4. doi: 10.1126/science.aac8385. Epub 2016 Feb 11.


Isolated flavonoids from Ficus racemosa stem bark possess antidiabetic, hypolipidemic and protective effects in albino Wistar rats.

Keshari AK, Kumar G, Kushwaha PS, Bhardwaj M, Kumar P, Rawat A, Kumar D, Prakash A, Ghosh B, Saha S.

J Ethnopharmacol. 2016 Apr 2;181:252-62. doi: 10.1016/j.jep.2016.02.004. Epub 2016 Feb 8.


MicroRNA 874-3p Exerts Skeletal Anabolic Effects Epigenetically during Weaning by Suppressing Hdac1 Expression.

Kushwaha P, Khedgikar V, Sharma D, Yuen T, Gautam J, Ahmad N, Karvande A, Mishra PR, Trivedi PK, Sun L, Bhadada SK, Zaidi M, Trivedi R.

J Biol Chem. 2016 Feb 19;291(8):3959-66. doi: 10.1074/jbc.M115.687152. Epub 2015 Dec 9.


Nearly free electrons in a 5d delafossite oxide metal.

Kushwaha P, Sunko V, Moll PJ, Bawden L, Riley JM, Nandi N, Rosner H, Schmidt MP, Arnold F, Hassinger E, Kim TK, Hoesch M, Mackenzie AP, King PD.

Sci Adv. 2015 Oct 23;1(9):e1500692. doi: 10.1126/sciadv.1500692. eCollection 2015 Oct.


A rare case of vulval pilonidal sinus: incidental diagnosis.

Kushwaha P, Merritt A, Aslam MB.

BMJ Case Rep. 2015 Jul 27;2015. pii: bcr2014204693. doi: 10.1136/bcr-2014-204693.


Novel Chalcone-Thiazole Hybrids as Potent Inhibitors of Drug Resistant Staphylococcus aureus.

Sashidhara KV, Rao KB, Kushwaha P, Modukuri RK, Singh P, Soni I, Shukla PK, Chopra S, Pasupuleti M.

ACS Med Chem Lett. 2015 May 29;6(7):809-13. doi: 10.1021/acsmedchemlett.5b00169. eCollection 2015 Jul 9.

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