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The similarities and differences between pleuroparenchymal fibroelastosis and idiopathic pulmonary fibrosis.

Ishii H, Kinoshita Y, Kushima H, Nagata N, Watanabe K.

Chron Respir Dis. 2019 Jan-Dec;16:1479973119867945. doi: 10.1177/1479973119867945.


Serum Soluble Interleukin-2 Receptor Is a Biomarker for Pneumocystis jirovecii Pneumonia among Patients with Rheumatoid Arthritis under Methotrexate Therapy.

Sakamoto N, Hara S, Ishimoto H, Nakashima S, Yura H, Miyamura T, Okuno D, Hara A, Kakugawa T, Yamaguchi H, Obase Y, Kushima H, Ishii H, Noguchi S, Kido T, Kobayashi T, Soejima Y, Yoshioka S, Ishimatsu Y, Yatera K, Kadota JI, Mukae H.

Tohoku J Exp Med. 2019 Jul;248(3):209-216. doi: 10.1620/tjem.248.209.


Association of Immune Thrombocytopenia and Interstitial Pneumonia.

Kushima H, Kinoshita Y, Watanabe K, Takamatsu Y, Ishii H.

Intern Med. 2019 Jul 10. doi: 10.2169/internalmedicine.2664-19. [Epub ahead of print]


Lower-lobe predominant pleuroparenchymal fibroelastosis.

Kinoshita Y, Watanabe K, Ishii H, Kushima H, Nabeshima K.

Pathol Int. 2019 Sep;69(9):536-540. doi: 10.1111/pin.12827. Epub 2019 Jul 4.


Tumor Microembolism to Alveolar Capillaries.

Kinoshita Y, Ishii H, Kushima H, Watanabe K.

Intern Med. 2019 Oct 1;58(19):2899-2900. doi: 10.2169/internalmedicine.2934-19. Epub 2019 Jun 7. No abstract available.


Nesfatin-1 suppresses peripheral arterial remodeling without elevating blood pressure in mice.

Mori Y, Shimizu H, Kushima H, Saito T, Hiromura M, Terasaki M, Koshibu M, Ohtaki H, Hirano T.

Endocr Connect. 2019 May 1;8(5):536-546. doi: 10.1530/EC-19-0120.


Emphysematous cystitis in an elderly Japanese patient with type 2 diabetes mellitus.

Yashima H, Terasaki M, Kushima H, Hirano T.

Clin Case Rep. 2019 Feb 6;7(3):585-586. doi: 10.1002/ccr3.2028. eCollection 2019 Mar.


The upward shift of hilar structures and tracheal deviation in pleuroparenchymal fibroelastosis.

Ishii H, Kinoshita Y, Kushima H, Ogura T, Watanabe K.

Multidiscip Respir Med. 2019 Mar 7;14:10. doi: 10.1186/s40248-019-0173-8. eCollection 2019.


Antiatherogenic effects of liraglutide in hyperglycemic apolipoprotein E-null mice via AMP-activated protein kinase-independent mechanisms.

Koshibu M, Mori Y, Saito T, Kushima H, Hiromura M, Terasaki M, Takada M, Fukui T, Hirano T.

Am J Physiol Endocrinol Metab. 2019 May 1;316(5):E895-E907. doi: 10.1152/ajpendo.00511.2018. Epub 2019 Mar 12.


Distribution of emphysema and fibrosis in idiopathic pulmonary fibrosis with coexisting emphysema.

Kinoshita Y, Watanabe K, Ishii H, Kushima H, Fujita M, Nabeshima K.

Histopathology. 2019 Jun;74(7):1103-1108. doi: 10.1111/his.13831.


A Dipeptidyl Peptidase-4 Inhibitor Suppresses Macrophage Foam Cell Formation in Diabetic db/db Mice and Type 2 Diabetes Patients.

Terasaki M, Hiromura M, Mori Y, Kohashi K, Kushima H, Koshibu M, Saito T, Yashima H, Watanabe T, Hirano T.

Int J Endocrinol. 2018 Dec 9;2018:8458304. doi: 10.1155/2018/8458304. eCollection 2018.


Pheochromocytoma presenting with severe hyperglycemia and metabolic acidosis following intra-articular glucocorticoid administration: a case report.

Tomoyasu M, Mori Y, Fukase A, Kushima H, Hirano T.

J Med Case Rep. 2019 Jan 5;13(1):3. doi: 10.1186/s13256-018-1945-z.


Chronic Pulmonary Aspergillosis with Pleuroparenchymal Fibroelastosis-like Features.

Kushima H, Ishii H, Kinoshita Y, Fujita M, Watanabe K.

Intern Med. 2019 Apr 15;58(8):1137-1140. doi: 10.2169/internalmedicine.1930-18. Epub 2018 Dec 18.


Multiple Pulmonary Metastases of Cutaneous Squamous Cell Carcinoma.

Kushima H, Ishii H, Shima R, Kinoshita Y, Watanabe K, Fujita M.

Intern Med. 2019 Mar 15;58(6):833-835. doi: 10.2169/internalmedicine.1889-18. Epub 2018 Nov 19.


Pleuroparenchymal fibroelastosis as a histological background of autoimmune diseases.

Kinoshita Y, Watanabe K, Ishii H, Kushima H, Hamasaki M, Fujita M, Nabeshima K.

Virchows Arch. 2019 Jan;474(1):97-104. doi: 10.1007/s00428-018-2473-3. Epub 2018 Oct 16.


Multielement analysis of plant extracts with potential use in the treatment of peptic ulcers by synchrotron radiation total reflection X-ray fluorescence.

Vieira LD, da Silva KT, Giarola RS, Inocente GF, Kushima H, Hiruma Lima CA, Hormaza JM.

PeerJ. 2018 Sep 12;6:e5375. doi: 10.7717/peerj.5375. eCollection 2018.


Pleuroparenchymal fibroelastosis diagnosed by multidisciplinary discussions in Japan.

Ishii H, Watanabe K, Kushima H, Baba T, Watanabe S, Yamada Y, Arai T, Tsushima K, Kondoh Y, Nakamura Y, Terasaki Y, Hebisawa A, Johkoh T, Sakai F, Takemura T, Kawabata Y, Ogura T; Tokyo Diffuse Lung Disease Study Group.

Respir Med. 2018 Aug;141:190-197. doi: 10.1016/j.rmed.2018.06.022. Epub 2018 Jun 27.


The serum KL-6 levels in untreated idiopathic pulmonary fibrosis can naturally decline in association with disease progression.

Ishii H, Kushima H, Kinoshita Y, Fujita M, Watanabe K.

Clin Respir J. 2018 Sep;12(9):2411-2418. doi: 10.1111/crj.12946. Epub 2018 Aug 13.


Multiple circular pleural metastases of renal cell carcinoma.

Kushima H, Ishii H, Kinoshita Y, Fujita M, Watanabe K.

Respir Med Case Rep. 2018 Mar 27;24:30-31. doi: 10.1016/j.rmcr.2018.03.014. eCollection 2018.


The limited impact of psychiatric disease and psychotropic medication on the outcome of hospitalization for pneumonia.

Ishii H, Kushima H, Kinoshita Y, Matsumoto T, Watanabe K, Fujita M.

J Infect Chemother. 2018 Dec;24(12):1009-1012. doi: 10.1016/j.jiac.2018.04.015. Epub 2018 May 31.


Glucose-Dependent Insulinotropic Polypeptide Suppresses Peripheral Arterial Remodeling in Male Mice.

Mori Y, Kushima H, Koshibu M, Saito T, Hiromura M, Kohashi K, Terasaki M, Seino Y, Yamada Y, Hirano T.

Endocrinology. 2018 Jul 1;159(7):2717-2732. doi: 10.1210/en.2018-00336.


Significant increases in the density and number of lymphatic vessels in pleuroparenchymal fibroelastosis.

Kinoshita Y, Watanabe K, Ishii H, Kushima H, Fujita M, Nabeshima K.

Histopathology. 2018 Sep;73(3):417-427. doi: 10.1111/his.13634. Epub 2018 Jun 6.


High-dose steroid therapy for acute respiratory distress syndrome lacking common risk factors: predictors of outcome.

Kinoshita Y, Ishii H, Kushima H, Watanabe K, Fujita M.

Acute Med Surg. 2017 Oct 25;5(2):146-153. doi: 10.1002/ams2.321. eCollection 2018 Apr.


Marfan syndrome presenting with diffuse emphysematous change of the lung.

Ishii H, Shima R, Kinoshita Y, Kushima H.

BMJ Case Rep. 2018 Feb 3;2018. pii: bcr-2017-224056. doi: 10.1136/bcr-2017-224056. No abstract available.


Endobronchial Lipoma: The Diagnostic Benefit of Computed Tomography Findings.

On R, Kushima H, Ishii H, Watanabe K.

Intern Med. 2018 Jan 15;57(2):285-286. doi: 10.2169/internalmedicine.9289-17. Epub 2017 Oct 16. No abstract available.


The role of endothelial nitric oxide in the anti-restenotic effects of liraglutide in a mouse model of restenosis.

Kushima H, Mori Y, Koshibu M, Hiromura M, Kohashi K, Terasaki M, Fukui T, Hirano T.

Cardiovasc Diabetol. 2017 Oct 2;16(1):122. doi: 10.1186/s12933-017-0603-x.


Proliferation of elastic fibres in idiopathic pulmonary fibrosis: a whole-slide image analysis and comparison with pleuroparenchymal fibroelastosis.

Kinoshita Y, Watanabe K, Ishii H, Kushima H, Fujita M, Nabeshima K.

Histopathology. 2017 Dec;71(6):934-942. doi: 10.1111/his.13312. Epub 2017 Sep 22.


Increased blood pressure in nesfatin/nuclebindin-2-transgenic mice.

Mori Y, Shimizu H, Kushima H, Hiromura M, Terasaki M, Tanaka M, Osaki A, Hirano T.

Hypertens Res. 2017 Oct 5;40(10):861-867. doi: 10.1038/hr.2017.61. Epub 2017 Apr 27.


Pulmonary Sarcoidosis Presenting with Thin-walled Small Cysts.

Kushima H, Ishii H, Kadota JI, Watanabe K.

Intern Med. 2017;56(8):985-986. doi: 10.2169/internalmedicine.56.7766. Epub 2017 Apr 15. No abstract available.


Combination Therapy with a Sodium-Glucose Cotransporter 2 Inhibitor and a Dipeptidyl Peptidase-4 Inhibitor Additively Suppresses Macrophage Foam Cell Formation and Atherosclerosis in Diabetic Mice.

Terasaki M, Hiromura M, Mori Y, Kohashi K, Kushima H, Ohara M, Watanabe T, Andersson O, Hirano T.

Int J Endocrinol. 2017;2017:1365209. doi: 10.1155/2017/1365209. Epub 2017 Mar 19.


The usefulness of monomeric periostin as a biomarker for idiopathic pulmonary fibrosis.

Ohta S, Okamoto M, Fujimoto K, Sakamoto N, Takahashi K, Yamamoto H, Kushima H, Ishii H, Akasaka K, Ono J, Kamei A, Azuma Y, Matsumoto H, Yamaguchi Y, Aihara M, Johkoh T, Kawaguchi A, Ichiki M, Sagara H, Kadota JI, Hanaoka M, Hayashi SI, Kohno S, Hoshino T, Izuhara K; Consortium for Development of Diagnostics for Pulmonary Fibrosis Patients (CoDD-PF).

PLoS One. 2017 Mar 29;12(3):e0174547. doi: 10.1371/journal.pone.0174547. eCollection 2017.


A New Amino Acid Substitution at G150S in Lanosterol 14-α Demethylase (Erg11 protein) in Multi-azole-resistant Trichosporon asahii.

Kushima H, Tokimatsu I, Ishii H, Kawano R, Watanabe K, Kadota JI.

Med Mycol J. 2017;58(1):E23-E28. doi: 10.3314/mmj.16-00027.


Two cases of pleuroparenchymal fibroelastosis diagnosed with transbronchial lung biopsy.

Kushima H, Hidaka K, Ishii H, Nakao A, On R, Kinoshita Y, Fujita M, Nabashima K, Watanabe K.

Respir Med Case Rep. 2016 Jul 18;19:71-3. doi: 10.1016/j.rmcr.2016.07.008. eCollection 2016.


Suppressive Effects of Glucose-Dependent Insulinotropic Polypeptide on Cardiac Hypertrophy and Fibrosis in Angiotensin II-Infused Mouse Models.

Hiromura M, Mori Y, Kohashi K, Terasaki M, Shinmura K, Negoro T, Kawashima H, Kogure M, Wachi T, Watanabe R, Sato K, Kushima H, Tomoyasu M, Nakano Y, Yamada Y, Watanabe T, Hirano T.

Circ J. 2016 Aug 25;80(9):1988-97. doi: 10.1253/circj.CJ-16-0152. Epub 2016 Jul 1.


Invasive Pulmonary Aspergillosis Presenting with Tracheobronchial Involvement.

Kushima H, Tokimatsu I, Ishii H, Kadota J.

Intern Med. 2016;55(12):1679. doi: 10.2169/internalmedicine.55.6822. Epub 2016 Jun 15. No abstract available.


Disseminated tuberculosis with acute respiratory distress syndrome lacking granuloma formation in the lung.

Nakao A, Ishii H, Igata F, Kushima H, Fujita M, Hisano S, Watanabe K.

J Infect Chemother. 2016 Sep;22(9):638-41. doi: 10.1016/j.jiac.2016.02.002. Epub 2016 Mar 10.


Comet Tail Sign in IgG4-related Disease.

Yamasue M, Kushima H, Ishii H, Kadota J.

Intern Med. 2016;55(2):213-4. doi: 10.2169/internalmedicine.55.5944. Epub 2016 Jan 15. No abstract available.


[Antifungal susceptibility and drug-resistant mechanism of Trichosporon].

Kushima H, Tokimatsu I, Ishii H, Kadota J.

Med Mycol J. 2015;56(4):J123-8. doi: 10.3314/mmj.56.J123. Review. Japanese.


Amelioration of Hyperglycemia with a Sodium-Glucose Cotransporter 2 Inhibitor Prevents Macrophage-Driven Atherosclerosis through Macrophage Foam Cell Formation Suppression in Type 1 and Type 2 Diabetic Mice.

Terasaki M, Hiromura M, Mori Y, Kohashi K, Nagashima M, Kushima H, Watanabe T, Hirano T.

PLoS One. 2015 Nov 25;10(11):e0143396. doi: 10.1371/journal.pone.0143396. eCollection 2015.


A Dipeptidyl Peptidase-4 Inhibitor but not Incretins Suppresses Abdominal Aortic Aneurysms in Angiotensin II-Infused Apolipoprotein E-Null Mice.

Kohashi K, Hiromura M, Mori Y, Terasaki M, Watanabe T, Kushima H, Shinmura K, Tomoyasu M, Nagashima M, Hirano T.

J Atheroscler Thromb. 2016;23(4):441-54. doi: 10.5551/jat.31997. Epub 2015 Nov 9.


Effects of Sulfamethoxazole-Trimethoprim on Airway Colonization with Pneumocystis jirovecii.

Kushima H, Ishii H, Tokimatsu I, Umeki K, Sato T, Kadota J.

Jpn J Infect Dis. 2016 May 20;69(3):252-5. doi: 10.7883/yoken.JJID.2014.546. Epub 2015 Aug 7.


Mediastinal Seminoma with an Elevated Level of Serum Angiotensin-converting Enzyme.

Ishii H, Igata F, Nabeshima K, Kushima H, Watanabe K.

Intern Med. 2015;54(15):1909-12. doi: 10.2169/internalmedicine.54.3953. Epub 2015 Aug 1.


Terminalia catappa L.: a medicinal plant from the Caribbean pharmacopeia with anti-Helicobacter pylori and antiulcer action in experimental rodent models.

Pinheiro Silva L, Damacena de Angelis C, Bonamin F, Kushima H, José Mininel F, Campaner Dos Santos L, Karina Delella F, Luis Felisbino S, Vilegas W, Regina Machado da Rocha L, Aparecido Dos Santos Ramos M, Maria Bauab T, Toma W, Akiko Hiruma-Lima C.

J Ethnopharmacol. 2015 Jan 15;159:285-95. doi: 10.1016/j.jep.2014.11.025. Epub 2014 Nov 24.


The case of primary endobronchial neurinoma.

Kushima H, Ishii H, Okada F, Kadota J.

BMJ Case Rep. 2014 Nov 20;2014. pii: bcr2014205844. doi: 10.1136/bcr-2014-205844. No abstract available.


Metalloproteinase Inhibition Protects against Reductions in Circulating Adrenomedullin during Lead-induced Acute Hypertension.

Nascimento RA, Mendes G, Possomato-Vieira JS, Gonçalves-Rizzi VH, Kushima H, Delella FK, Dias-Junior CA.

Basic Clin Pharmacol Toxicol. 2015 Jun;116(6):508-15. doi: 10.1111/bcpt.12337. Epub 2014 Nov 8.


Autopsy analyses in acute exacerbation of idiopathic pulmonary fibrosis.

Oda K, Ishimoto H, Yamada S, Kushima H, Ishii H, Imanaga T, Harada T, Ishimatsu Y, Matsumoto N, Naito K, Yatera K, Nakazato M, Kadota J, Watanabe K, Kohno S, Mukae H.

Respir Res. 2014 Sep 1;15:109. doi: 10.1186/s12931-014-0109-y.


Chest computed tomography findings in patients with angioimmunoblastic T-cell lymphoma.

Ishii H, Kushima H, Komiya K, Okada F, Watanabe K, Kadota J.

Respir Investig. 2014 Jul;52(4):265-8. doi: 10.1016/j.resinv.2014.01.001. Epub 2014 Feb 14. No abstract available.


Two cases of pulmonary lymphangioleiomyomatosis in postmenopausal women.

Ishii H, Kushima H, Watanabe K, Kadota J.

Respir Investig. 2014 Jul;52(4):261-4. doi: 10.1016/j.resinv.2014.02.002. Epub 2014 Mar 12. Review.


The effect of a minor constituent of essential oil from Citrus aurantium: the role of β-myrcene in preventing peptic ulcer disease.

Bonamin F, Moraes TM, Dos Santos RC, Kushima H, Faria FM, Silva MA, Junior IV, Nogueira L, Bauab TM, Souza Brito AR, da Rocha LR, Hiruma-Lima CA.

Chem Biol Interact. 2014 Apr 5;212:11-9. doi: 10.1016/j.cbi.2014.01.009. Epub 2014 Jan 27.


Healing actions of essential oils from Citrus aurantium and d-limonene in the gastric mucosa: the roles of VEGF, PCNA, and COX-2 in cell proliferation.

Moraes TM, Rozza AL, Kushima H, Pellizzon CH, Rocha LR, Hiruma-Lima CA.

J Med Food. 2013 Dec;16(12):1162-7. doi: 10.1089/jmf.2012.0259.


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