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Items: 1 to 50 of 150

1.

[Follicle-Stimulating Hormone and Estradiol Levels in Japanese Women Treated with Toremifene and Anastrozole for Two Years - A Retrospective Analysis of Data from a Prospective Randomized Trial].

Anan K, Mitsuyama S, Yanagita Y, Kimura M, Doihara H, Komaki K, Kusama M, Ikeda T.

Gan To Kagaku Ryoho. 2018 Dec;45(12):1725-1728. Japanese.

PMID:
30587728
2.

Serum lipid and bone metabolism effects of Toremifene vs. Letrozole as adjuvant therapy for postmenopausal early breast cancer patients: results of a multicenter open randomized study.

Shien T, Doihara H, Sato N, Anan K, Komaki K, Miyauchi K, Yanagita Y, Fujisawa T, Mitsuyama S, Kanbayashi C, Kusama M, Kimura M, Jinno H, Sano M, Ikeda T.

Cancer Chemother Pharmacol. 2018 Feb;81(2):269-275. doi: 10.1007/s00280-017-3491-6. Epub 2017 Dec 1.

3.

Influence of a dosing-time on toxicities induced by docetaxel, cisplatin and 5-fluorouracil in patients with oral squamous cell carcinoma; a cross-over pilot study.

Tsuchiya Y, Ushijima K, Noguchi T, Okada N, Hayasaka JI, Jinbu Y, Ando H, Mori Y, Kusama M, Fujimura A.

Chronobiol Int. 2018 Feb;35(2):289-294. doi: 10.1080/07420528.2017.1392551. Epub 2017 Nov 16.

PMID:
29144178
4.

Effect of re-coaching on self-injection of insulin in older diabetic patients - Impact of cognitive impairment.

Omori K, Kawamura T, Urata M, Matsuura M, Kusama M, Imamine R, Watarai A, Nakashima E, Umemura T, Hotta N.

Diabetes Res Clin Pract. 2017 Aug;130:34-42. doi: 10.1016/j.diabres.2017.05.011. Epub 2017 May 12.

PMID:
28554141
5.

Factors Associated with Changes in Brain Atrophy during a Three-Year Observation in Elderly Diabetic Patients: Effect of Renal Impairment on Hippocampal Atrophy.

Kawamura T, Umemura T, Umegaki H, Imamine R, Kawano N, Mase H, Mizoguchi A, Minatoguchi M, Kusama M, Kouchi Y, Watarai A, Kanai A, Nakashima E, Hotta N.

Dement Geriatr Cogn Dis Extra. 2016 Feb 17;6(1):55-67. doi: 10.1159/000443497. eCollection 2016 Jan-Apr.

6.

A method to visualize transdermal nickel permeation in mouse skin using a nickel allergy patch.

Sugiyama T, Uo M, Wada T, Hongo T, Omagari D, Komiyama K, Oikawa M, Kusama M, Mori Y.

Biomed Mater Eng. 2015;26(1-2):1-8. doi: 10.3233/BME-151543.

7.

Organ Impairment-Drug-Drug Interaction Database: A Tool for Evaluating the Impact of Renal or Hepatic Impairment and Pharmacologic Inhibition on the Systemic Exposure of Drugs.

Yeung CK, Yoshida K, Kusama M, Zhang H, Ragueneau-Majlessi I, Argon S, Li L, Chang P, Le CD, Zhao P, Zhang L, Sugiyama Y, Huang SM.

CPT Pharmacometrics Syst Pharmacol. 2015 Aug;4(8):489-94. doi: 10.1002/psp4.55. Epub 2015 Jul 14.

8.

Detection of trace metallic elements in oral lichenoid contact lesions using SR-XRF, PIXE, and XAFS.

Sugiyama T, Uo M, Wada T, Omagari D, Komiyama K, Miyazaki S, Numako C, Noguchi T, Jinbu Y, Kusama M, Mori Y.

Sci Rep. 2015 Jun 18;5:10672. doi: 10.1038/srep10672.

9.

Relationship between health literacy, health information access, health behavior, and health status in Japanese people.

Suka M, Odajima T, Okamoto M, Sumitani M, Igarashi A, Ishikawa H, Kusama M, Yamamoto M, Nakayama T, Sugimori H.

Patient Educ Couns. 2015 May;98(5):660-8. doi: 10.1016/j.pec.2015.02.013. Epub 2015 Feb 23.

PMID:
25739344
10.

The effect size, study design, and development experience in commercially sponsored studies for new drug applications in approved drugs.

Fukunaga S, Kusama M, Ono S.

Springerplus. 2014 Dec 15;3:740. doi: 10.1186/2193-1801-3-740. eCollection 2014.

11.

[Reinforcement of warfarin action in a patient administered S-1].

Watanabe H, Itoh H, Tsuchiya Y, Miyagi N, Sugiyama T, Nakai Y, Shinozaki Y, Noguchi T, Jinbu Y, Kusama M.

Gan To Kagaku Ryoho. 2015 Jan;42(1):131-3. Review. Japanese.

PMID:
25596696
12.

Estimation of trace metal elements in oral mucosa specimens by using SR-XRF, PIXE, and XAFS.

Sugiyama T, Uo M, Wada T, Omagari D, Komiyama K, Noguchi T, Jinbu Y, Kusama M.

Biometals. 2015 Feb;28(1):11-20. doi: 10.1007/s10534-014-9796-6. Epub 2014 Dec 19.

PMID:
25522792
13.

Novel metal allergy patch test using metal nanoballs.

Sugiyama T, Uo M, Wada T, Hongo T, Omagari D, Komiyama K, Sasaki H, Takahashi H, Kusama M, Mori Y.

J Nanobiotechnology. 2014 Dec 3;12:51. doi: 10.1186/s12951-014-0051-7.

14.

Effect of renal impairment on cognitive function during a 3-year follow up in elderly patients with type 2 diabetes: Association with microinflammation.

Kawamura T, Umemura T, Umegaki H, Imamine R, Kawano N, Tanaka C, Kawai M, Minatoguchi M, Kusama M, Kouchi Y, Watarai A, Kanai A, Nakashima E, Hotta N.

J Diabetes Investig. 2014 Sep;5(5):597-605. doi: 10.1111/jdi.12190. Epub 2014 Feb 4.

15.

In silico prediction of major drug clearance pathways by support vector machines with feature-selected descriptors.

Toshimoto K, Wakayama N, Kusama M, Maeda K, Sugiyama Y, Akiyama Y.

Drug Metab Dispos. 2014 Nov;42(11):1811-9. doi: 10.1124/dmd.114.057893. Epub 2014 Aug 14.

PMID:
25128502
16.

A proposal of a pharmacokinetic/pharmacodynamic (PK/PD) index map for selecting an optimal PK/PD index from conventional indices (AUC/MIC, Cmax/MIC, and TAM) for antibiotics.

Kitamura Y, Yoshida K, Kusama M, Sugiyama Y.

Drug Metab Pharmacokinet. 2014;29(6):455-62. doi: 10.2133/dmpk.DMPK-14-RG-013. Epub 2014 Jul 8.

17.

Validity and reliability of the Japanese version of the Newest Vital Sign: a preliminary study.

Kogure T, Sumitani M, Suka M, Ishikawa H, Odajima T, Igarashi A, Kusama M, Okamoto M, Sugimori H, Kawahara K.

PLoS One. 2014 Apr 24;9(4):e94582. doi: 10.1371/journal.pone.0094582. eCollection 2014.

18.

Relationship between appearance of tongue carcinoma on intraoral ultrasonography and histopathologic findings.

Shinozaki Y, Jinbu Y, Ito H, Noguchi T, Kusama M, Matsumoto N, Komiyama K, Taniguchi N.

Oral Surg Oral Med Oral Pathol Oral Radiol. 2014 May;117(5):634-639. doi: 10.1016/j.oooo.2014.02.001. Epub 2014 Feb 13. Erratum in: Oral Surg Oral Med Oral Pathol Oral Radiol. 2014 Oct;118(4):511.

PMID:
24725990
19.

Effect of articulatory rehabilitation after oral cancer surgery on higher brain activation.

Okada N, Sasaguri K, Otsuka T, Fujita A, Ito H, Noguchi T, Jinbu Y, Kusama M.

Int J Oral Maxillofac Surg. 2014 Aug;43(8):933-40. doi: 10.1016/j.ijom.2014.02.013. Epub 2014 Mar 25.

PMID:
24679850
20.

Effects of stress on mouse β-defensin-3 expression in the upper digestive mucosa.

Kawashima R, Shimizu T, To M, Saruta J, Jinbu Y, Kusama M, Tsukinoki K.

Yonsei Med J. 2014 Mar;55(2):387-94. doi: 10.3349/ymj.2014.55.2.387.

21.

Assessment of factors associated with dose differences between Japan and the United States.

Arnold FL, Fukunaga S, Kusama M, Matsuki N, Ono S.

Clin Pharmacol Ther. 2014 May;95(5):542-9. doi: 10.1038/clpt.2013.231. Epub 2013 Nov 26.

PMID:
24281222
22.

Involvement of Wee1 in the circadian rhythm-dependent intestinal damage induced by docetaxel.

Obi-Ioka Y, Ushijima K, Kusama M, Ishikawa-Kobayashi E, Fujimura A.

J Pharmacol Exp Ther. 2013 Oct;347(1):242-8. doi: 10.1124/jpet.113.203299. Epub 2013 Jul 26.

PMID:
23892568
23.

Different contributions of internal reviewers and external experts to labelling decisions on therapeutic indications in new drug reviews in Japan.

Yokota M, Kusama M, Matsuki N, Ono S.

J Clin Pharm Ther. 2013 Dec;38(6):456-61. doi: 10.1111/jcpt.12086. Epub 2013 Jul 14.

PMID:
23848321
24.

The 14-item health literacy scale for Japanese adults (HLS-14).

Suka M, Odajima T, Kasai M, Igarashi A, Ishikawa H, Kusama M, Nakayama T, Sumitani M, Sugimori H.

Environ Health Prev Med. 2013 Sep;18(5):407-15. doi: 10.1007/s12199-013-0340-z. Epub 2013 May 21.

25.

Assessment of statin-associated muscle toxicity in Japan: a cohort study conducted using claims database and laboratory information.

Chang CH, Kusama M, Ono S, Sugiyama Y, Orii T, Akazawa M.

BMJ Open. 2013 Apr 11;3(4). pii: e002040. doi: 10.1136/bmjopen-2012-002040. Print 2013.

26.

Involvement of prolactin-releasing peptide in the activation of oxytocin neurones in response to food intake.

Yamashita M, Takayanagi Y, Yoshida M, Nishimori K, Kusama M, Onaka T.

J Neuroendocrinol. 2013 May;25(5):455-65. doi: 10.1111/jne.12019.

27.

Factors associated with spontaneous reporting of adverse drug reactions in Japan.

Yamada T, Watanabe Y, Kusama M, Sugiyama Y, Ono S.

Pharmacoepidemiol Drug Saf. 2013 May;22(5):468-76. doi: 10.1002/pds.3378. Epub 2012 Nov 21.

PMID:
23172714
28.

General rules for clinical and pathological studies on oral cancer: a synopsis.

Izumo T, Kirita T, Ariji E, Ozeki S, Okada N, Okabe S, Okazaki Y, Omura K, Kusama M, Sato T, Shinohara M, Shimozato K, Shintani S, Tanaka Y, Nakayama E, Hayashi T, Miyazaki A, Yagishita H, Yamane M; Working Group 1 on the ‘Guidelines for Clinical and Pathological Studies of Oral Cancer’, Scientific Committee, Japan Society for Oral Tumors.

Jpn J Clin Oncol. 2012 Nov;42(11):1099-109. doi: 10.1093/jjco/hys141. Epub 2012 Sep 28.

PMID:
23024282
29.

Effect of local anesthesia on trigeminal somatosensory-evoked magnetic fields.

Otsuka T, Dan H, Dan I, Sase M, Sano T, Tsuzuki D, Fujita A, Sasaguri K, Okada N, Kusama M, Jinbu Y, Watanabe E.

J Dent Res. 2012 Dec;91(12):1196-201. doi: 10.1177/0022034512462398. Epub 2012 Sep 26.

PMID:
23018817
30.

Cost-effectiveness analysis of microdose clinical trials in drug development.

Yamane N, Igarashi A, Kusama M, Maeda K, Ikeda T, Sugiyama Y.

Drug Metab Pharmacokinet. 2013;28(3):187-95. Epub 2012 Sep 11.

32.

Analysis of regulatory review times of new drugs in Japan: association with characteristics of new drug applications, regulatory agency, and pharmaceutical companies.

Ishibashi T, Kusama M, Sugiyama Y, Ono S.

J Clin Pharm Ther. 2012 Dec;37(6):657-63. doi: 10.1111/j.1365-2710.2012.01363.x. Epub 2012 Jun 27.

PMID:
22734557
33.

Drug Utilization Reviews by Community Pharmacists in Japan: Identification of Potential Safety Concerns through the Brown Bag Program.

Akazawa M, Nomura K, Kusama M, Igarashi A.

Value Health Reg Issues. 2012 May;1(1):98-104. doi: 10.1016/j.vhri.2012.03.001. Epub 2012 May 25.

PMID:
29702835
34.

Inclusion of human intravenous study data in new drug applications-impact of the Japanese guidance.

Imawaka H, Kusama M, Ito K, Ono S, Sugiyama Y.

J Pharm Sci. 2012 Jul;101(7):2557-63. doi: 10.1002/jps.23135. Epub 2012 Apr 12.

PMID:
22499211
35.

Analysis of the success rates of new drug development in Japan and the lag behind the US.

Hirai Y, Yamanaka Y, Kusama M, Ishibashi T, Sugiyama Y, Ono S.

Health Policy. 2012 Mar;104(3):241-6. doi: 10.1016/j.healthpol.2011.11.008. Epub 2011 Dec 14.

PMID:
22172246
36.

Evaluation of the use of the tobacco PR-1a promoter to monitor defense gene expression by the luciferase bioluminescence reporter system.

Ono S, Kusama M, Ogura R, Hiratsuka K.

Biosci Biotechnol Biochem. 2011;75(9):1796-800. Epub 2011 Sep 7.

37.

Analysis of labeling decisions regarding therapeutic indications during new drug application reviews in Japan.

Yokota M, Kusama M, Sugiyama Y, Ono S.

Clin Pharmacol Ther. 2011 Sep;90(3):432-41. doi: 10.1038/clpt.2011.134. Epub 2011 Aug 3.

PMID:
21814198
38.

Effects of toremifene and anastrozole on serum lipids and bone metabolism in postmenopausal females with estrogen receptor-positive breast cancer: the results of a 2-year multicenter open randomized study.

Anan K, Mitsuyama S, Yanagita Y, Kimura M, Doihara H, Komaki K, Kusama M, Ikeda T.

Breast Cancer Res Treat. 2011 Aug;128(3):775-81. doi: 10.1007/s10549-011-1608-x. Epub 2011 Jun 3.

PMID:
21638048
39.

Clinical relevance of liquid chromatography tandem mass spectrometry as an analytical method in microdose clinical studies.

Yamane N, Tozuka Z, Kusama M, Maeda K, Ikeda T, Sugiyama Y.

Pharm Res. 2011 Aug;28(8):1963-72. doi: 10.1007/s11095-011-0423-8. Epub 2011 Apr 7.

PMID:
21472491
40.
41.

Bare bone graft with vascularised iliac crest for mandibular reconstruction.

Sarukawa S, Noguchi T, Oh-iwa I, Sunaga A, Uda H, Kusama M, Sugawara Y.

J Craniomaxillofac Surg. 2012 Jan;40(1):61-6. doi: 10.1016/j.jcms.2011.01.017. Epub 2011 Feb 25.

PMID:
21353578
42.
43.

Ethnic differences in pharmacokinetics in new drug applications and approved doses in Japan.

Fukunaga S, Kusama M, Arnold FL, Ono S.

J Clin Pharmacol. 2011 Aug;51(8):1237-40. doi: 10.1177/0091270010381500. Epub 2011 Jan 5. No abstract available.

PMID:
21209235
44.

Analysis of pharmaceutical safety-related regulatory actions in Japan: do tradeoffs exist between safer drugs and launch delay?

Yamada T, Kusama M, Hirai Y, Arnold F, Sugiyama Y, Ono S.

Ann Pharmacother. 2010 Dec;44(12):1976-85. doi: 10.1345/aph.1P153. Epub 2010 Nov 23.

PMID:
21098757
45.

Clinical development and review times for new drugs in Japan: associated factors.

Ishibashi T, Yasuda K, Kusama M, Sugiyama Y, Ono S.

Clin Pharmacol Ther. 2010 Oct;88(4):487-91. doi: 10.1038/clpt.2010.108. Epub 2010 Aug 25.

PMID:
20739921
46.

Failure of liver function tests in predicting drug clearance of chemotherapeutic agents in a patient who had recovered from hepatic congestion.

Tsubokura M, Miura Y, Itokawa T, Takei N, Higaki T, Amaki T, Ishida Y, Kusama M, Ono S, Narimatsu H, Kami M, Komatsu T.

Br J Clin Pharmacol. 2010 Aug;70(2):277-9. doi: 10.1111/j.1365-2125.2010.03693.x. No abstract available.

47.

In silico classification of major clearance pathways of drugs with their physiochemical parameters.

Kusama M, Toshimoto K, Maeda K, Hirai Y, Imai S, Chiba K, Akiyama Y, Sugiyama Y.

Drug Metab Dispos. 2010 Aug;38(8):1362-70. doi: 10.1124/dmd.110.032789. Epub 2010 Apr 27.

PMID:
20423955
48.

Exploring differences in drug doses between Japan and Western countries.

Arnold FL, Kusama M, Ono S.

Clin Pharmacol Ther. 2010 Jun;87(6):714-20. doi: 10.1038/clpt.2010.31. Epub 2010 Apr 21.

PMID:
20410879
49.

Delays in new drug applications in Japan and industrial R&D strategies.

Hirai Y, Kinoshita H, Kusama M, Yasuda K, Sugiyama Y, Ono S.

Clin Pharmacol Ther. 2010 Feb;87(2):212-8. doi: 10.1038/clpt.2009.215. Epub 2009 Nov 25.

PMID:
19940847
50.

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