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In vivo imaging of the buccal mucosa shows loss of the endothelial glycocalyx and perivascular hemorrhages in pediatric Plasmodium falciparum malaria.

Lyimo E, Haslund LE, Ramsing T, Wang CW, Efunshile AM, Manjurano A, Makene V, Lusingu J, Theander TG, Kurtzhals JAL, Paulsen R, Hempel C.

Infect Immun. 2019 Dec 23. pii: IAI.00679-19. doi: 10.1128/IAI.00679-19. [Epub ahead of print]


Critical evaluation of the appetite test for children with severe acute malnutrition.

Zangenberg M, Abdissa A, Johansen ØH, Tesfaw G, Friis H, Briend A, Eshetu B, Kurtzhals JAL, Girma T.

Trop Med Int Health. 2019 Dec 11. doi: 10.1111/tmi.13360. [Epub ahead of print]


Genetic relationship between bacteria isolated from intraoperative air samples and surgical site infections at a major teaching hospital in Ghana.

Stauning MA, Bediako-Bowan A, Bjerrum S, Andersen LP, Andreu-Sánchez S, Labi AK, Kurtzhals JAL, Marvig RL, Opintan JA.

J Hosp Infect. 2019 Nov 16. pii: S0195-6701(19)30476-1. doi: 10.1016/j.jhin.2019.11.007. [Epub ahead of print]


Infectious diseases detected by screening after arrival to Denmark in internationally adopted children.

Nielsen AV, Kjaergaard J, Pedersen TM, Helmuth IG, Nygaard U, Nielsen HW, Christensen VB, Kurtzhals JAL, Poulsen A.

Acta Paediatr. 2019 Oct 3. doi: 10.1111/apa.15045. [Epub ahead of print]


Prolonged and persistent diarrhoea is not restricted to children with acute malnutrition: an observational study in Ethiopia.

Zangenberg M, Johansen ØH, Abdissa A, Eshetu B, Kurtzhals JAL, Friis H, Sommerfelt H, Langeland N, Hanevik K.

Trop Med Int Health. 2019 Sep;24(9):1088-1097. doi: 10.1111/tmi.13291. Epub 2019 Aug 16.


Antibiotic use in surgical units of selected hospitals in Ghana: a multi-centre point prevalence survey.

Bediako-Bowan AAA, Owusu E, Labi AK, Obeng-Nkrumah N, Sunkwa-Mills G, Bjerrum S, Opintan JA, Bannerman C, Mølbak K, Kurtzhals JAL, Newman MJ.

BMC Public Health. 2019 Jun 21;19(1):797. doi: 10.1186/s12889-019-7162-x.


Metronidazole-sensitive organisms in children with severe acute malnutrition: an evaluation of the indication for empiric metronidazole treatment.

Zangenberg M, Abdissa A, Johansen ØH, Tesfaw G, Girma T, Kurtzhals JAL.

Clin Microbiol Infect. 2019 Jun 8. pii: S1198-743X(19)30285-X. doi: 10.1016/j.cmi.2019.05.022. [Epub ahead of print]


Population Pharmacokinetic Estimates Suggest Elevated Clearance and Distribution Volume of Desethylamodiaquine in Pediatric Patients with Sickle Cell Disease Treated with Artesunate-Amodiaquine.

Adjei GO, Amponsah SK, Goka BQ, Enweronu-Laryea C, Renner L, Sulley AM, Alifrangis M, Kurtzhals JAL.

Curr Ther Res Clin Exp. 2019 Jan 12;90:9-15. doi: 10.1016/j.curtheres.2019.01.005. eCollection 2019.


Antibiotic prescribing in paediatric inpatients in Ghana: a multi-centre point prevalence survey.

Labi AK, Obeng-Nkrumah N, Sunkwa-Mills G, Bediako-Bowan A, Akufo C, Bjerrum S, Owusu E, Enweronu-Laryea C, Opintan JA, Kurtzhals JAL, Newman MJ.

BMC Pediatr. 2018 Dec 20;18(1):391. doi: 10.1186/s12887-018-1367-5.


Malaria causes long-term effects on markers of iron status in children: a critical assessment of existing clinical and epidemiological tools.

Castberg FC, Sarbah EW, Koram KA, Opoku N, Ofori MF, Styrishave B, Hviid L, Kurtzhals JAL.

Malar J. 2018 Dec 11;17(1):464. doi: 10.1186/s12936-018-2609-6.


Diagnostic accuracy of the 1,3-β-D-glucan test for pneumocystis pneumonia in a tertiary university hospital in Denmark: A retrospective study.

Engsbro AL, Najat S, Jørgensen KM, Kurtzhals JAL, Arendrup MC.

Med Mycol. 2018 Dec 11. doi: 10.1093/mmy/myy129. [Epub ahead of print]


Experimental cerebral malaria is associated with profound loss of both glycan and protein components of the endothelial glycocalyx.

Hempel C, Sporring J, Kurtzhals JAL.

FASEB J. 2019 Feb;33(2):2058-2071. doi: 10.1096/fj.201800657R. Epub 2018 Sep 18.


Schistosomiasis Presenting as Recurring Sigmoid Volvulus in a Danish Man With an Inconspicuous Travel History-A Case Report.

Krog AD, Axelsson JM, Bondgaard AR, Kurtzhals JA.

Open Forum Infect Dis. 2018 Mar 19;5(4):ofy057. doi: 10.1093/ofid/ofy057. eCollection 2018 Apr.


Increased Plasmodium chabaudi malaria mortality in mice with nutritional iron deficiency can be reduced by short-term adjunctive iron supplementation.

Castberg FC, Maretty L, Staalsoe T, Hempel C, Clasen-Linde E, Hviid L, Kurtzhals JAL.

Malar J. 2018 Jan 16;17(1):34. doi: 10.1186/s12936-018-2186-8.


Traffic flow and microbial air contamination in operating rooms at a major teaching hospital in Ghana.

Stauning MT, Bediako-Bowan A, Andersen LP, Opintan JA, Labi AK, Kurtzhals JAL, Bjerrum S.

J Hosp Infect. 2018 Jul;99(3):263-270. doi: 10.1016/j.jhin.2017.12.010. Epub 2017 Dec 16.


Population Pharmacokinetic Characteristics of Amikacin in Suspected Cases of Neonatal Sepsis in a Low-Resource African Setting: A Prospective Nonrandomized Single-Site Study.

Amponsah SK, Adjei GO, Enweronu-Laryea C, Bugyei KA, Hadji-Popovski K, Kurtzhals JAL, Kristensen K.

Curr Ther Res Clin Exp. 2017 Jan 20;84:e1-e6. doi: 10.1016/j.curtheres.2017.01.001. eCollection 2017.


Binding of Plasmodium falciparum to CD36 can be shielded by the glycocalyx.

Hempel C, Wang CW, Kurtzhals JAL, Staalsø T.

Malar J. 2017 May 10;16(1):193. doi: 10.1186/s12936-017-1844-6.


Erratum to: Glucagon-like peptide-1 analogue, liraglutide, in experimental cerebral malaria: implications for the role of oxidative stress in cerebral malaria.

DellaValle B, Hempel C, Staalsoe T, Johansen FF, Kurtzhals JAL.

Malar J. 2016 Sep 27;15:495. doi: 10.1186/s12936-016-1544-7. eCollection 2016.


Glucagon-like peptide-1 analogue, liraglutide, in experimental cerebral malaria: implications for the role of oxidative stress in cerebral malaria.

DellaValle B, Hempel C, Staalsoe T, Johansen FF, Kurtzhals JA.

Malar J. 2016 Aug 24;15(1):427. doi: 10.1186/s12936-016-1486-0. Erratum in: Malar J. 2016;15(1):495. Malar J. 2016 Sep 27;15:495.


Endothelial Glycocalyx: Shedding Light on Malaria Pathogenesis.

Hempel C, Pasini EM, Kurtzhals JAL.

Trends Mol Med. 2016 Jun;22(6):453-457. doi: 10.1016/j.molmed.2016.04.004. Epub 2016 May 5. Review.


New filtration system for efficient recovery of waterborne Cryptosporidium oocysts and Giardia cysts.

Al-Sabi MN, Gad JA, Riber U, Kurtzhals JA, Enemark HL.

J Appl Microbiol. 2015 Sep;119(3):894-903. doi: 10.1111/jam.12898. Epub 2015 Aug 12.


Molecular Detection of the Carriage Rate of Four Intestinal Protozoa with Real-Time Polymerase Chain Reaction: Possible Overdiagnosis of Entamoeba histolytica in Nigeria.

Efunshile MA, Ngwu BA, Kurtzhals JA, Sahar S, König B, Stensvold CR.

Am J Trop Med Hyg. 2015 Aug;93(2):257-62. doi: 10.4269/ajtmh.14-0781. Epub 2015 Jun 22.


Polymorphisms in the Haem Oxygenase-1 promoter are not associated with severity of Plasmodium falciparum malaria in Ghanaian children.

Hansson HH, Maretty L, Balle C, Goka BQ, Luzon E, Nkrumah FN, Schousboe ML, Rodrigues OP, Bygbjerg IC, Kurtzhals JA, Alifrangis M, Hempel C.

Malar J. 2015 Apr 11;14:153. doi: 10.1186/s12936-015-0668-5.


An automated method for determining the cytoadhesion of Plasmodium falciparum-infected erythrocytes to immobilized cells.

Hempel C, Boisen IM, Efunshile A, Kurtzhals JA, Staalsø T.

Malar J. 2015 Mar 14;14:112. doi: 10.1186/s12936-015-0632-4.


Epidemiological study of the association between malaria and helminth infections in Nigeria.

Efunshile AM, Olawale T, Stensvold CR, Kurtzhals JA, König B.

Am J Trop Med Hyg. 2015 Mar;92(3):578-82. doi: 10.4269/ajtmh.14-0548. Epub 2015 Jan 26.


GLP-1 improves neuropathology after murine cold lesion brain trauma.

DellaValle B, Hempel C, Johansen FF, Kurtzhals JA.

Ann Clin Transl Neurol. 2014 Sep;1(9):721-32. doi: 10.1002/acn3.99. Epub 2014 Sep 30. Erratum in: Ann Clin Transl Neurol. 2016 Aug;3(8):664.


Plasmodium falciparum avoids change in erythrocytic surface expression of phagocytosis markers during inhibition of nitric oxide synthase activity.

Hempel C, Kohnke H, Maretty L, Jensen PØ, Staalsø T, Kurtzhals JA.

Mol Biochem Parasitol. 2014 Nov;198(1):29-36. doi: 10.1016/j.molbiopara.2014.11.003. Epub 2014 Nov 29.


A randomized trial of artesunate-amodiaquine versus artemether-lumefantrine in Ghanaian paediatric sickle cell and non-sickle cell disease patients with acute uncomplicated malaria.

Adjei GO, Goka BQ, Enweronu-Laryea CC, Rodrigues OP, Renner L, Sulley AM, Alifrangis M, Khalil I, Kurtzhals JA.

Malar J. 2014 Sep 19;13:369. doi: 10.1186/1475-2875-13-369.


Systemic and Cerebral Vascular Endothelial Growth Factor Levels Increase in Murine Cerebral Malaria along with Increased Calpain and Caspase Activity and Can be Reduced by Erythropoietin Treatment.

Hempel C, Hoyer N, Kildemoes A, Jendresen CB, Kurtzhals JA.

Front Immunol. 2014 Jun 19;5:291. doi: 10.3389/fimmu.2014.00291. eCollection 2014.


Implementation of minimally invasive and objective humane endpoints in the study of murine Plasmodium infections.

Dellavalle B, Kirchhoff J, Maretty L, Castberg FC, Kurtzhals JA.

Parasitology. 2014 Jul 4:1-7. [Epub ahead of print]


Effects of the vascular endothelial growth factor receptor-2 (VEGFR-2) inhibitor SU5416 on in vitro cultures of Plasmodium falciparum.

Hempel C, Hoyer N, Staalsø T, Kurtzhals JA.

Malar J. 2014 May 28;13:201. doi: 10.1186/1475-2875-13-201.


Endothelial glycocalyx on brain endothelial cells is lost in experimental cerebral malaria.

Hempel C, Hyttel P, Kurtzhals JA.

J Cereb Blood Flow Metab. 2014 Jul;34(7):1107-10. doi: 10.1038/jcbfm.2014.79. Epub 2014 Apr 23.


Human genetic polymorphisms in the Knops blood group are not associated with a protective advantage against Plasmodium falciparum malaria in Southern Ghana.

Hansson HH, Kurtzhals JA, Goka BQ, Rodriques OP, Nkrumah FN, Theander TG, Bygbjerg IC, Alifrangis M.

Malar J. 2013 Nov 7;12:400. doi: 10.1186/1475-2875-12-400.


Outbreak of pneumocystis pneumonia in renal and liver transplant patients caused by genotypically distinct strains of Pneumocystis jirovecii.

Rostved AA, Sassi M, Kurtzhals JA, Sørensen SS, Rasmussen A, Ross C, Gogineni E, Huber C, Kutty G, Kovacs JA, Helweg-Larsen J.

Transplantation. 2013 Nov 15;96(9):834-42. doi: 10.1097/TP.0b013e3182a1618c.


Investigation of hydrogen sulfide gas as a treatment against P. falciparum, murine cerebral malaria, and the importance of thiolation state in the development of cerebral malaria.

DellaValle B, Staalsoe T, Kurtzhals JA, Hempel C.

PLoS One. 2013;8(3):e59271. doi: 10.1371/journal.pone.0059271. Epub 2013 Mar 26.


Reversible audiometric threshold changes in children with uncomplicated malaria.

Adjei GO, Goka BQ, Kitcher E, Rodrigues OP, Badoe E, Kurtzhals JA.

J Trop Med. 2013;2013:360540. doi: 10.1155/2013/360540. Epub 2013 Mar 7.


Electrocardiographic study in Ghanaian children with uncomplicated malaria, treated with artesunate-amodiaquine or artemether-lumefantrine.

Adjei GO, Oduro-Boatey C, Rodrigues OP, Hoegberg LC, Alifrangis M, Kurtzhals JA, Goka BQ.

Malar J. 2012 Dec 17;11:420. doi: 10.1186/1475-2875-11-420.


Brain mitochondrial function in a murine model of cerebral malaria and the therapeutic effects of rhEPO.

Karlsson M, Hempel C, Sjövall F, Hansson MJ, Kurtzhals JA, Elmér E.

Int J Biochem Cell Biol. 2013 Jan;45(1):151-5. doi: 10.1016/j.biocel.2012.08.008. Epub 2012 Aug 10.


Insights into deregulated TNF and IL-10 production in malaria: implications for understanding severe malarial anaemia.

Boeuf PS, Loizon S, Awandare GA, Tetteh JK, Addae MM, Adjei GO, Goka B, Kurtzhals JA, Puijalon O, Hviid L, Akanmori BD, Behr C.

Malar J. 2012 Aug 1;11:253. doi: 10.1186/1475-2875-11-253.


Erythropoietin treatment alleviates ultrastructural myelin changes induced by murine cerebral malaria.

Hempel C, Hyttel P, Staalsø T, Nyengaard JR, Kurtzhals JA.

Malar J. 2012 Jun 28;11:216. doi: 10.1186/1475-2875-11-216.


Intravenous ferric carboxymaltose accelerates erythropoietic recovery from experimental malarial anemia.

Maretty L, Sharp RE, Andersson M, Kurtzhals JA.

J Infect Dis. 2012 Apr 1;205(7):1173-7. doi: 10.1093/infdis/jis020. Epub 2012 Feb 21.


CNS hypoxia is more pronounced in murine cerebral than noncerebral malaria and is reversed by erythropoietin.

Hempel C, Combes V, Hunt NH, Kurtzhals JA, Grau GE.

Am J Pathol. 2011 Oct;179(4):1939-50. doi: 10.1016/j.ajpath.2011.06.027. Epub 2011 Aug 18.


Subconjunctival Dirofilaria repens Infestation: A Light and Scanning Electron Microscopy Study.

Melsom HA, Kurtzhals JA, Qvortrup K, Bargum R, Barfod TS, la Cour M, Heegaard S.

Open Ophthalmol J. 2011;5:21-4. doi: 10.2174/1874364101105010021. Epub 2011 Apr 14.


Differential microRNA expression in experimental cerebral and noncerebral malaria.

El-Assaad F, Hempel C, Combes V, Mitchell AJ, Ball HJ, Kurtzhals JA, Hunt NH, Mathys JM, Grau GE.

Infect Immun. 2011 Jun;79(6):2379-84. doi: 10.1128/IAI.01136-10. Epub 2011 Mar 21.


The effect of vitamin A supplementation and diphtheria-tetanus-pertussis vaccination on parasitaemia in an experimental murine malaria model.

Jørgensen MJ, Hein-Kristensen L, Hempel C, Ravn H, Wiese L, Kurtzhals JA, Benn CS.

Scand J Infect Dis. 2011 Apr;43(4):296-303. doi: 10.3109/00365548.2010.535845. Epub 2010 Nov 25.


Plasmodium berghei ANKA: erythropoietin activates neural stem cells in an experimental cerebral malaria model.

Core A, Hempel C, Kurtzhals JA, Penkowa M.

Exp Parasitol. 2011 Feb;127(2):500-5. doi: 10.1016/j.exppara.2010.09.010. Epub 2010 Oct 30.


Retinopathy in severe malaria in Ghanaian children--overlap between fundus changes in cerebral and non-cerebral malaria.

Essuman VA, Ntim-Amponsah CT, Astrup BS, Adjei GO, Kurtzhals JA, Ndanu TA, Goka B.

Malar J. 2010 Aug 12;9:232. doi: 10.1186/1475-2875-9-232.


Imported melioidosis in Danish travellers: a diagnostic challenge.

Badran S, Pedersen TI, Roed C, Lunding S, Birk N, Vestergaard H, Røder B, Lillelund HK, Kurtzhals JA, Kemp M, Christensen JJ.

Scand J Infect Dis. 2010 Jul;42(6-7):445-9. doi: 10.3109/00365540903582467.


Parents' perceptions, attitudes and acceptability of treatment of childhood malaria with artemisinin combination therapies in ghana.

Adjei GO, Darkwah AK, Goka BQ, Bart-Plange C, Alifrangis ML, Kurtzhals JA, Rodrigues OP.

Ghana Med J. 2009 Sep;43(3):99-106.

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