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Items: 1 to 50 of 57

1.

A novel Staphylococcus aureus vaccine: iron surface determinant B induces rapid antibody responses in rhesus macaques and specific increased survival in a murine S. aureus sepsis model.

Kuklin NA, Clark DJ, Secore S, Cook J, Cope LD, McNeely T, Noble L, Brown MJ, Zorman JK, Wang XM, Pancari G, Fan H, Isett K, Burgess B, Bryan J, Brownlow M, George H, Meinz M, Liddell ME, Kelly R, Schultz L, Montgomery D, Onishi J, Losada M, Martin M, Ebert T, Tan CY, Schofield TL, Nagy E, Meineke A, Joyce JG, Kurtz MB, Caulfield MJ, Jansen KU, McClements W, Anderson AS.

Infect Immun. 2006 Apr;74(4):2215-23.

2.

Cell-based assays to detect inhibitors of fungal mRNA capping enzymes and characterization of sinefungin as a cap methyltransferase inhibitor.

Chrebet GL, Wisniewski D, Perkins AL, Deng Q, Kurtz MB, Marcy A, Parent SA.

J Biomol Screen. 2005 Jun;10(4):355-64.

PMID:
15964937
3.

Inactivation of Kex2p diminishes the virulence of Candida albicans.

Newport G, Kuo A, Flattery A, Gill C, Blake JJ, Kurtz MB, Abruzzo GK, Agabian N.

J Biol Chem. 2003 Jan 17;278(3):1713-20. Epub 2002 Nov 4.

4.

The antifungal echinocandin caspofungin acetate kills growing cells of Aspergillus fumigatus in vitro.

Bowman JC, Hicks PS, Kurtz MB, Rosen H, Schmatz DM, Liberator PA, Douglas CM.

Antimicrob Agents Chemother. 2002 Sep;46(9):3001-12.

5.

Arundifungin, a novel antifungal compound produced by fungi: biological activity and taxonomy of the producing organisms.

Cabello MA, Platas G, Collado J, Díez MT, Martín I, Vicente F, Meinz M, Onishi JC, Douglas C, Thompson J, Kurtz MB, Schwartz RE, Bills GF, Giacobbe RA, Abruzzo GK, Flattery AM, Kong L, Peláez F.

Int Microbiol. 2001 Jun;4(2):93-102.

PMID:
11770831
6.

Antimicrobial activity of ergokonin A from Trichoderma longibrachiatum.

Vicente MF, Cabello A, Platas G, Basilio A, Díez MT, Dreikorn S, Giacobbe RA, Onishi JC, Meinz M, Kurtz MB, Rosenbach M, Thompson J, Abruzzo G, Flattery A, Kong L, Tsipouras A, Wilson KE, Peláez F.

J Appl Microbiol. 2001 Nov;91(5):806-13.

7.

Glucan synthase inhibitors as antifungal agents.

Kurtz MB, Rex JH.

Adv Protein Chem. 2001;56:423-75. Review. No abstract available.

PMID:
11329859
8.

The discovery of enfumafungin, a novel antifungal compound produced by an endophytic Hormonema species biological activity and taxonomy of the producing organisms.

Peláez F, Cabello A, Platas G, Díez MT, González del Val A, Basilio A, Martán I, Vicente F, Bills GE, Giacobbe RA, Schwartz RE, Onish JC, Meinz MS, Abruzzo GK, Flattery AM, Kong L, Kurtz MB.

Syst Appl Microbiol. 2000 Oct;23(3):333-43.

PMID:
11108011
9.

Molecular cloning and characterization of a lipid phosphohydrolase that degrades sphingosine-1- phosphate and induces cell death.

Mandala SM, Thornton R, Galve-Roperh I, Poulton S, Peterson C, Olivera A, Bergstrom J, Kurtz MB, Spiegel S.

Proc Natl Acad Sci U S A. 2000 Jul 5;97(14):7859-64.

10.

Discovery of novel antifungal (1,3)-beta-D-glucan synthase inhibitors.

Onishi J, Meinz M, Thompson J, Curotto J, Dreikorn S, Rosenbach M, Douglas C, Abruzzo G, Flattery A, Kong L, Cabello A, Vicente F, Pelaez F, Diez MT, Martin I, Bills G, Giacobbe R, Dombrowski A, Schwartz R, Morris S, Harris G, Tsipouras A, Wilson K, Kurtz MB.

Antimicrob Agents Chemother. 2000 Feb;44(2):368-77.

11.

Purification of geranylgeranyltransferase I from Candida albicans and cloning of the CaRAM2 and CaCDC43 genes encoding its subunits.

Mazur P, Register E, Bonfiglio CA, Yuan X, Kurtz MB, Williamson JM, Kelly R.

Microbiology. 1999 May;145 ( Pt 5):1123-35.

PMID:
10376828
12.

Inhibition of fungal sphingolipid biosynthesis by rustmicin, galbonolide B and their new 21-hydroxy analogs.

Harris GH, Shafiee A, Cabello MA, Curotto JE, Genilloud O, Göklen KE, Kurtz MB, Rosenbach M, Salmon PM, Thornton RA, Zink DL, Mandala SM.

J Antibiot (Tokyo). 1998 Sep;51(9):837-44.

13.

Rustmicin, a potent antifungal agent, inhibits sphingolipid synthesis at inositol phosphoceramide synthase.

Mandala SM, Thornton RA, Milligan J, Rosenbach M, Garcia-Calvo M, Bull HG, Harris G, Abruzzo GK, Flattery AM, Gill CJ, Bartizal K, Dreikorn S, Kurtz MB.

J Biol Chem. 1998 Jun 12;273(24):14942-9.

14.

Sphingoid base 1-phosphate phosphatase: a key regulator of sphingolipid metabolism and stress response.

Mandala SM, Thornton R, Tu Z, Kurtz MB, Nickels J, Broach J, Menzeleev R, Spiegel S.

Proc Natl Acad Sci U S A. 1998 Jan 6;95(1):150-5.

15.

Khafrefungin, a novel inhibitor of sphingolipid synthesis.

Mandala SM, Thornton RA, Rosenbach M, Milligan J, Garcia-Calvo M, Bull HG, Kurtz MB.

J Biol Chem. 1997 Dec 19;272(51):32709-14.

16.

Identification of the FKS1 gene of Candida albicans as the essential target of 1,3-beta-D-glucan synthase inhibitors.

Douglas CM, D'Ippolito JA, Shei GJ, Meinz M, Onishi J, Marrinan JA, Li W, Abruzzo GK, Flattery A, Bartizal K, Mitchell A, Kurtz MB.

Antimicrob Agents Chemother. 1997 Nov;41(11):2471-9.

17.

Viridiofungins, novel inhibitors of sphingolipid synthesis.

Mandala SM, Thornton RA, Frommer BR, Dreikorn S, Kurtz MB.

J Antibiot (Tokyo). 1997 Apr;50(4):339-43.

18.

Antimicrobial activity of viridiofungins.

Onishi JC, Milligan JA, Basilio A, Bergstrom J, Curotto J, Huang L, Meinz M, Nallin-Omstead M, Pelaez F, Rew D, Salvatore M, Thompson J, Vicente F, Kurtz MB.

J Antibiot (Tokyo). 1997 Apr;50(4):334-8.

19.

Lipopeptide inhibitors of fungal glucan synthase.

Kurtz MB, Douglas CM.

J Med Vet Mycol. 1997 Mar-Apr;35(2):79-86. Review.

PMID:
9147267
20.

Characterization of echinocandin-resistant mutants of Candida albicans: genetic, biochemical, and virulence studies.

Kurtz MB, Abruzzo G, Flattery A, Bartizal K, Marrinan JA, Li W, Milligan J, Nollstadt K, Douglas CM.

Infect Immun. 1996 Aug;64(8):3244-51.

21.

Aerosol and parenteral pneumocandins are effective in a rat model of pulmonary aspergillosis.

Kurtz MB, Bernard EM, Edwards FF, Marrinan JA, Dropinski J, Douglas CM, Armstrong D.

Antimicrob Agents Chemother. 1995 Aug;39(8):1784-9.

22.

The discovery of australifungin, a novel inhibitor of sphinganine N-acyltransferase from Sporormiella australis. Producing organism, fermentation, isolation, and biological activity.

Mandala SM, Thornton RA, Frommer BR, Curotto JE, Rozdilsky W, Kurtz MB, Giacobbe RA, Bills GF, Cabello MA, Martín I, et al.

J Antibiot (Tokyo). 1995 May;48(5):349-56.

23.

Increased antifungal activity of L-733,560, a water-soluble, semisynthetic pneumocandin, is due to enhanced inhibition of cell wall synthesis.

Kurtz MB, Douglas C, Marrinan J, Nollstadt K, Onishi J, Dreikorn S, Milligan J, Mandala S, Thompson J, Balkovec JM, et al.

Antimicrob Agents Chemother. 1994 Dec;38(12):2750-7.

24.

Detection of metabolic disorders among selectively screened people with idiopathic mental retardation.

Kurtz MB, Finucane B, Hyland K, Bottiglieri T, Sherwood WG, Bennett MJ.

Ment Retard. 1994 Oct;32(5):328-33.

PMID:
7984117
25.

A Saccharomyces cerevisiae mutant with echinocandin-resistant 1,3-beta-D-glucan synthase.

Douglas CM, Marrinan JA, Li W, Kurtz MB.

J Bacteriol. 1994 Sep;176(18):5686-96.

26.

Morphological effects of lipopeptides against Aspergillus fumigatus correlate with activities against (1,3)-beta-D-glucan synthase.

Kurtz MB, Heath IB, Marrinan J, Dreikorn S, Onishi J, Douglas C.

Antimicrob Agents Chemother. 1994 Jul;38(7):1480-9. Erratum in: Antimicrob Agents Chemother 1994 Oct;38(10):2516.

27.

Inhibition of serine palmitoyl-transferase activity by lipoxamycin.

Mandala SM, Frommer BR, Thornton RA, Kurtz MB, Young NM, Cabello MA, Genilloud O, Liesch JM, Smith JL, Horn WS.

J Antibiot (Tokyo). 1994 Mar;47(3):376-9. No abstract available.

28.

Synthesis and antifungal activity of novel cationic pneumocandin B(o) derivatives.

Bouffard FA, Zambias RA, Dropinski JF, Balkovec JM, Hammond ML, Abruzzo GK, Bartizal KF, Marrinan JA, Kurtz MB, McFadden DC, et al.

J Med Chem. 1994 Jan 21;37(2):222-5. No abstract available.

PMID:
8295208
29.

The spasmodic upper-body squeeze: a characteristic behavior in Smith-Magenis syndrome.

Finucane BM, Konar D, Haas-Givler B, Kurtz MB, Scott CI Jr.

Dev Med Child Neurol. 1994 Jan;36(1):78-83.

PMID:
8132119
30.

Mosaicism for deletion 17p11.2 in a boy with the Smith-Magenis syndrome.

Finucane BM, Kurtz MB, Babu VR, Scott CI Jr.

Am J Med Genet. 1993 Feb 15;45(4):447-9.

PMID:
8465848
31.

Eye abnormalities in the Smith-Magenis contiguous gene deletion syndrome.

Finucane BM, Jaeger ER, Kurtz MB, Weinstein M, Scott CI Jr.

Am J Med Genet. 1993 Feb 15;45(4):443-6.

PMID:
8465847
32.

Sphingofungins E and F: novel serinepalmitoyl transferase inhibitors from Paecilomyces variotii.

Horn WS, Smith JL, Bills GF, Raghoobar SL, Helms GL, Kurtz MB, Marrinan JA, Frommer BR, Thornton RA, Mandala SM.

J Antibiot (Tokyo). 1992 Oct;45(10):1692-6. No abstract available.

33.

New mental retardation syndrome with hearing impairment, distinct facial appearance, and skeletal anomalies.

Finucane B, Kurtz MB, Scott CI Jr.

Am J Med Genet. 1992 Jul 15;43(5):844-7.

PMID:
1642273
34.

Cloning and characterization of the plasma membrane H(+)-ATPase from Candida albicans.

Monk BC, Kurtz MB, Marrinan JA, Perlin DS.

J Bacteriol. 1991 Nov;173(21):6826-36.

35.

Concurrence of dominant piebald trait and fragile X syndrome.

Finucane B, Scott CI Jr, Kurtz MB.

Am J Hum Genet. 1991 Apr;48(4):815. No abstract available.

36.

Psychotropic drug use in institutionalized people with mental retardation.

Bond WS, Mandos LA, Kurtz MB.

DICP. 1989 Nov;23(11):924-5. No abstract available.

PMID:
2596139
37.

Midazolam for aggressivity and violence in three mentally retarded patients.

Bond WS, Mandos LA, Kurtz MB.

Am J Psychiatry. 1989 Jul;146(7):925-6.

PMID:
2742020
38.

Isolation of hem3 mutants from Candida albicans by sequential gene disruption.

Kurtz MB, Marrinan J.

Mol Gen Genet. 1989 May;217(1):47-52.

PMID:
2671651
39.

One-step gene disruption by cotransformation to isolate double auxotrophs in Candida albicans.

Kelly R, Miller SM, Kurtz MB.

Mol Gen Genet. 1988 Sep;214(1):24-31.

PMID:
2976118
40.

The molecular genetics of Candida albicans.

Kurtz MB, Kirsch DR, Kelly R.

Microbiol Sci. 1988 Feb;5(2):58-63. Review.

PMID:
3079219
41.

Development of autonomously replicating plasmids for Candida albicans.

Kurtz MB, Cortelyou MW, Miller SM, Lai M, Kirsch DR.

Mol Cell Biol. 1987 Jan;7(1):209-17.

42.

Directed mutagenesis in Candida albicans: one-step gene disruption to isolate ura3 mutants.

Kelly R, Miller SM, Kurtz MB, Kirsch DR.

Mol Cell Biol. 1987 Jan;7(1):199-208.

43.

Integrative transformation of Candida albicans, using a cloned Candida ADE2 gene.

Kurtz MB, Cortelyou MW, Kirsch DR.

Mol Cell Biol. 1986 Jan;6(1):142-9.

44.

Neurologic manifestations of the organoid nevus syndrome.

Clancy RR, Kurtz MB, Baker D, Sladky JT, Honig PJ, Younkin DP.

Arch Neurol. 1985 Mar;42(3):236-40.

PMID:
3977653
45.

Mutants of Aspergillus nidulans blocked at an early stage of sporulation secrete an unusual metabolite.

Butnick NZ, Yager LN, Hermann TE, Kurtz MB, Champe SP.

J Bacteriol. 1984 Nov;160(2):533-40.

46.

Genetic analysis of mutants of Aspergillus nidulans blocked at an early stage of sporulation.

Butnick NZ, Yager LN, Kurtz MB, Champe SP.

J Bacteriol. 1984 Nov;160(2):541-5.

47.

Developmental defects resulting from arginine auxotrophy in Aspergillus nidulans.

Serlupi-Crescenzi O, Kurtz MB, Champe SP.

J Gen Microbiol. 1983 Nov;129(11):3535-44.

PMID:
6363619
48.

Laccase localized in hulle cells and cleistothecial primordia of Aspergillus nidulans.

Hermann TE, Kurtz MB, Champe SP.

J Bacteriol. 1983 May;154(2):955-64.

49.
50.

Temperature-shift analysis of conidial development in Aspergillus nidulans.

Yager LN, Kurtz MB, Champe SP.

Dev Biol. 1982 Sep;93(1):92-103. No abstract available.

PMID:
6813166

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