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Items: 1 to 50 of 143

1.

Reply to J. Wang et al.

Kurtz DM, Scherer F, Jin MC, Soo J, Craig AFM, Esfahani MS, Chabon JJ, Stehr H, Liu CL, Tibshirani R, Maeda LS, Gupta NK, Khodadoust MS, Advani RH, Newman AM, Dührsen U, Hüttmann A, Meignan M, Casasnovas O, Westin JR, Roschewski M, Wilson WH, Gaidano G, Rossi D, Diehn M, Alizadeh AA.

J Clin Oncol. 2019 Mar 20;37(9):755-757. doi: 10.1200/JCO.18.01907. Epub 2019 Feb 12. No abstract available.

PMID:
30753108
2.

Acrylamide Production in Autoclaved Rodent Feed.

Kurtz DM, Glascoe R, Caviness G, Locklear J, Whiteside T, Ward T, Adsit F, Lih F, Deterding LJ, Churchwell MI, Doerge DR, Kissling GE.

J Am Assoc Lab Anim Sci. 2018 Oct 25. doi: 10.30802/AALAS-JAALAS-18-000011. [Epub ahead of print]

3.

Circulating Tumor DNA Measurements As Early Outcome Predictors in Diffuse Large B-Cell Lymphoma.

Kurtz DM, Scherer F, Jin MC, Soo J, Craig AFM, Esfahani MS, Chabon JJ, Stehr H, Liu CL, Tibshirani R, Maeda LS, Gupta NK, Khodadoust MS, Advani RH, Levy R, Newman AM, Dührsen U, Hüttmann A, Meignan M, Casasnovas RO, Westin JR, Roschewski M, Wilson WH, Gaidano G, Rossi D, Diehn M, Alizadeh AA.

J Clin Oncol. 2018 Oct 1;36(28):2845-2853. doi: 10.1200/JCO.2018.78.5246. Epub 2018 Aug 20.

PMID:
30125215
4.

Trojan Horse for Light-Triggered Bifurcated Production of Singlet Oxygen and Fenton-Reactive Iron within Cancer Cells.

Cioloboc D, Kennedy C, Boice EN, Clark ER, Kurtz DM Jr.

Biomacromolecules. 2018 Jan 8;19(1):178-187. doi: 10.1021/acs.biomac.7b01433. Epub 2017 Dec 14.

PMID:
29192767
5.

Early Detection of Molecular Residual Disease in Localized Lung Cancer by Circulating Tumor DNA Profiling.

Chaudhuri AA, Chabon JJ, Lovejoy AF, Newman AM, Stehr H, Azad TD, Khodadoust MS, Esfahani MS, Liu CL, Zhou L, Scherer F, Kurtz DM, Say C, Carter JN, Merriott DJ, Dudley JC, Binkley MS, Modlin L, Padda SK, Gensheimer MF, West RB, Shrager JB, Neal JW, Wakelee HA, Loo BW Jr, Alizadeh AA, Diehn M.

Cancer Discov. 2017 Dec;7(12):1394-1403. doi: 10.1158/2159-8290.CD-17-0716. Epub 2017 Sep 24.

6.

Spectroscopy and DFT Calculations of a Flavo-diiron Enzyme Implicate New Diiron Site Structures.

Weitz AC, Giri N, Caranto JD, Kurtz DM Jr, Bominaar EL, Hendrich MP.

J Am Chem Soc. 2017 Aug 30;139(34):12009-12019. doi: 10.1021/jacs.7b06546. Epub 2017 Aug 16.

7.

High-throughput sequencing for noninvasive disease detection in hematologic malignancies.

Scherer F, Kurtz DM, Diehn M, Alizadeh AA.

Blood. 2017 Jul 27;130(4):440-452. doi: 10.1182/blood-2017-03-735639. Epub 2017 Jun 9. Review.

8.

Photosensitized H2 Production Using a Zinc Porphyrin-Substituted Protein, Platinum Nanoparticles, and Ascorbate with No Electron Relay: Participation of Good's Buffers.

Clark ER, Kurtz DM Jr.

Inorg Chem. 2017 Apr 17;56(8):4585-4594. doi: 10.1021/acs.inorgchem.7b00228. Epub 2017 Mar 31.

PMID:
28362081
9.

Molecular profiling of single circulating tumor cells from lung cancer patients.

Park SM, Wong DJ, Ooi CC, Kurtz DM, Vermesh O, Aalipour A, Suh S, Pian KL, Chabon JJ, Lee SH, Jamali M, Say C, Carter JN, Lee LP, Kuschner WG, Schwartz EJ, Shrager JB, Neal JW, Wakelee HA, Diehn M, Nair VS, Wang SX, Gambhir SS.

Proc Natl Acad Sci U S A. 2016 Dec 27;113(52):E8379-E8386. doi: 10.1073/pnas.1608461113. Epub 2016 Dec 12.

10.

Corrigendum: Circulating tumour DNA profiling reveals heterogeneity of EGFR inhibitor resistance mechanisms in lung cancer patients.

Chabon JJ, Simmons AD, Lovejoy AF, Esfahani MS, Newman AM, Haringsma HJ, Kurtz DM, Stehr H, Scherer F, Karlovich CA, Harding TC, Durkin KA, Otterson GA, Thomas Purcell W, Ross Camidge D, Goldman JW, Sequist LV, Piotrowska Z, Wakelee HA, Neal JW, Alizadeh AA, Diehn M.

Nat Commun. 2016 Nov 14;7:13513. doi: 10.1038/ncomms13513. No abstract available.

11.

Distinct biological subtypes and patterns of genome evolution in lymphoma revealed by circulating tumor DNA.

Scherer F, Kurtz DM, Newman AM, Stehr H, Craig AF, Esfahani MS, Lovejoy AF, Chabon JJ, Klass DM, Liu CL, Zhou L, Glover C, Visser BC, Poultsides GA, Advani RH, Maeda LS, Gupta NK, Levy R, Ohgami RS, Kunder CA, Diehn M, Alizadeh AA.

Sci Transl Med. 2016 Nov 9;8(364):364ra155.

12.

Circulating tumour DNA profiling reveals heterogeneity of EGFR inhibitor resistance mechanisms in lung cancer patients.

Chabon JJ, Simmons AD, Lovejoy AF, Esfahani MS, Newman AM, Haringsma HJ, Kurtz DM, Stehr H, Scherer F, Karlovich CA, Harding TC, Durkin KA, Otterson GA, Purcell WT, Camidge DR, Goldman JW, Sequist LV, Piotrowska Z, Wakelee HA, Neal JW, Alizadeh AA, Diehn M.

Nat Commun. 2016 Jun 10;7:11815. doi: 10.1038/ncomms11815. Erratum in: Nat Commun. 2016 Nov 14;7:13513.

13.

Integrated digital error suppression for improved detection of circulating tumor DNA.

Newman AM, Lovejoy AF, Klass DM, Kurtz DM, Chabon JJ, Scherer F, Stehr H, Liu CL, Bratman SV, Say C, Zhou L, Carter JN, West RB, Sledge GW, Shrager JB, Loo BW Jr, Neal JW, Wakelee HA, Diehn M, Alizadeh AA.

Nat Biotechnol. 2016 May;34(5):547-555. doi: 10.1038/nbt.3520. Epub 2016 Mar 28.

14.

Active Site Metal Occupancy and Cyclic Di-GMP Phosphodiesterase Activity of Thermotoga maritima HD-GYP.

Miner KD, Kurtz DM Jr.

Biochemistry. 2016 Feb 16;55(6):970-9. doi: 10.1021/acs.biochem.5b01227. Epub 2016 Feb 1.

15.

Photosensitized H2 generation from "one-pot" and "two-pot" assemblies of a zinc-porphyrin/platinum nanoparticle/protein scaffold.

Clark ER, Kurtz DM Jr.

Dalton Trans. 2016 Jan 14;45(2):630-8. doi: 10.1039/c5dt03418c.

PMID:
26616549
16.

Corrigendum: Organocatalytic removal of formaldehyde adducts from RNA and DNA bases.

Karmakar S, Harcourt EM, Hewings DS, Scherer F, Lovejoy AF, Kurtz DM, Ehrenschwender T, Barandun LJ, Roost C, Alizadeh AA, Kool ET.

Nat Chem. 2015 Dec;7(12):1033. doi: 10.1038/nchem.2401. No abstract available.

PMID:
26587722
17.

CD/MCD/VTVH-MCD Studies of Escherichia coli Bacterioferritin Support a Binuclear Iron Cofactor Site.

Kwak Y, Schwartz JK, Huang VW, Boice E, Kurtz DM Jr, Solomon EI.

Biochemistry. 2015 Dec 1;54(47):7010-8. doi: 10.1021/acs.biochem.5b01033. Epub 2015 Nov 18.

PMID:
26551523
18.

Organocatalytic removal of formaldehyde adducts from RNA and DNA bases.

Karmakar S, Harcourt EM, Hewings DS, Scherer F, Lovejoy AF, Kurtz DM, Ehrenschwender T, Barandun LJ, Roost C, Alizadeh AA, Kool ET.

Nat Chem. 2015 Sep;7(9):752-8. doi: 10.1038/nchem.2307. Epub 2015 Aug 3. Erratum in: Nat Chem. 2015 Dec;7(12):1033.

19.

Next-generation surveillance strategies for patients with lymphoma.

Cohen JB, Kurtz DM, Staton AD, Flowers CR.

Future Oncol. 2015;11(13):1977-91. doi: 10.2217/fon.15.92. Review.

20.

Noninvasive monitoring of diffuse large B-cell lymphoma by immunoglobulin high-throughput sequencing.

Kurtz DM, Green MR, Bratman SV, Scherer F, Liu CL, Kunder CA, Takahashi K, Glover C, Keane C, Kihira S, Visser B, Callahan J, Kong KA, Faham M, Corbelli KS, Miklos D, Advani RH, Levy R, Hicks RJ, Hertzberg M, Ohgami RS, Gandhi MK, Diehn M, Alizadeh AA.

Blood. 2015 Jun 11;125(24):3679-87. doi: 10.1182/blood-2015-03-635169. Epub 2015 Apr 17.

21.

Dioxygen and nitric oxide scavenging by Treponema denticola flavodiiron protein: a mechanistic paradigm for catalysis.

Frederick RE, Caranto JD, Masitas CA, Gebhardt LL, MacGowan CE, Limberger RJ, Kurtz DM Jr.

J Biol Inorg Chem. 2015 Apr;20(3):603-13. doi: 10.1007/s00775-015-1248-4. Epub 2015 Feb 21.

22.

Tracking cellular and immune therapies in cancer.

Kurtz DM, Gambhir SS.

Adv Cancer Res. 2014;124:257-96. doi: 10.1016/B978-0-12-411638-2.00008-2. Review.

PMID:
25287692
23.

A diferrous-dinitrosyl intermediate in the N2O-generating pathway of a deflavinated flavo-diiron protein.

Caranto JD, Weitz A, Giri N, Hendrich MP, Kurtz DM Jr.

Biochemistry. 2014 Sep 9;53(35):5631-7. doi: 10.1021/bi500836z. Epub 2014 Aug 26.

24.

Rubredoxin refolding on nanostructured hydrophobic surfaces: evidence for a new type of biomimetic chaperones.

Miriani M, Iametti S, Kurtz DM, Bonomi F.

Proteins. 2014 Nov;82(11):3154-62. doi: 10.1002/prot.24675. Epub 2014 Sep 3.

PMID:
25143010
25.

The nitric oxide reductase mechanism of a flavo-diiron protein: identification of active-site intermediates and products.

Caranto JD, Weitz A, Hendrich MP, Kurtz DM Jr.

J Am Chem Soc. 2014 Jun 4;136(22):7981-92. doi: 10.1021/ja5022443. Epub 2014 May 23.

26.

Oxidative protection of hemoglobin and hemerythrin by cross-linking with a nonheme iron peroxidase: potentially improved oxygen carriers for use in blood substitutes.

Hathazi D, Mot AC, Vaida A, Scurtu F, Lupan I, Fischer-Fodor E, Damian G, Kurtz DM Jr, Silaghi-Dumitrescu R.

Biomacromolecules. 2014 May 12;15(5):1920-7. doi: 10.1021/bm5004256. Epub 2014 Apr 23.

PMID:
24716617
27.

H2O2-dependent substrate oxidation by an engineered diiron site in a bacterial hemerythrin.

Okamoto Y, Onoda A, Sugimoto H, Takano Y, Hirota S, Kurtz DM Jr, Shiro Y, Hayashi T.

Chem Commun (Camb). 2014 Apr 4;50(26):3421-3. doi: 10.1039/c3cc48108e. Epub 2014 Jan 8.

28.

Crystal structure, exogenous ligand binding, and redox properties of an engineered diiron active site in a bacterial hemerythrin.

Okamoto Y, Onoda A, Sugimoto H, Takano Y, Hirota S, Kurtz DM Jr, Shiro Y, Hayashi T.

Inorg Chem. 2013 Nov 18;52(22):13014-20. doi: 10.1021/ic401632x. Epub 2013 Nov 4.

29.

An HD-GYP cyclic di-guanosine monophosphate phosphodiesterase with a non-heme diiron-carboxylate active site.

Miner KD, Klose KE, Kurtz DM Jr.

Biochemistry. 2013 Aug 13;52(32):5329-31. doi: 10.1021/bi4009215. Epub 2013 Jul 29.

30.

A bacterial hemerythrin domain regulates the activity of a Vibrio cholerae diguanylate cyclase.

Schaller RA, Ali SK, Klose KE, Kurtz DM Jr.

Biochemistry. 2012 Oct 30;51(43):8563-70. doi: 10.1021/bi3011797. Epub 2012 Oct 18.

31.

Histidine ligand variants of a flavo-diiron protein: effects on structure and activities.

Fang H, Caranto JD, Mendoza R, Taylor AB, Hart PJ, Kurtz DM Jr.

J Biol Inorg Chem. 2012 Dec;17(8):1231-9. doi: 10.1007/s00775-012-0938-4. Epub 2012 Sep 19.

32.

Treponema denticola superoxide reductase: in vivo role, in vitro reactivities, and a novel [Fe(Cys)(4)] site.

Caranto JD, Gebhardt LL, MacGowan CE, Limberger RJ, Kurtz DM Jr.

Biochemistry. 2012 Jul 17;51(28):5601-10. Epub 2012 Jun 29.

33.

Vibrational analysis of mononitrosyl complexes in hemerythrin and flavodiiron proteins: relevance to detoxifying NO reductase.

Hayashi T, Caranto JD, Matsumura H, Kurtz DM Jr, Moënne-Loccoz P.

J Am Chem Soc. 2012 Apr 18;134(15):6878-84. doi: 10.1021/ja301812p. Epub 2012 Apr 9.

34.

An observational assessment method for aging laboratory rats.

Phillips PM, Jarema KA, Kurtz DM, MacPhail RC.

J Am Assoc Lab Anim Sci. 2010 Nov;49(6):792-9.

35.

Insights into the nitric oxide reductase mechanism of flavodiiron proteins from a flavin-free enzyme.

Hayashi T, Caranto JD, Wampler DA, Kurtz DM, Moënne-Loccoz P.

Biochemistry. 2010 Aug 24;49(33):7040-9. doi: 10.1021/bi100788y.

36.

Iron-nucleated folding of a metalloprotein in high urea: resolution of metal binding and protein folding events.

Morleo A, Bonomi F, Iametti S, Huang VW, Kurtz DM Jr.

Biochemistry. 2010 Aug 10;49(31):6627-34. doi: 10.1021/bi100630t.

37.

Towards the development of hemerythrin-based blood substitutes.

Mot AC, Roman A, Lupan I, Kurtz DM Jr, Silaghi-Dumitrescu R.

Protein J. 2010 Aug;29(6):387-93. doi: 10.1007/s10930-010-9264-2.

PMID:
20582620
38.

Prognostic role of vascular endothelial growth factor in hepatocellular carcinoma: systematic review and meta-analysis.

Schoenleber SJ, Kurtz DM, Talwalkar JA, Roberts LR, Gores GJ.

Br J Cancer. 2009 May 5;100(9):1385-92. doi: 10.1038/sj.bjc.6605017. Review.

39.

Pathway for H2O2 and O2 detoxification in Clostridium acetobutylicum.

Riebe O, Fischer RJ, Wampler DA, Kurtz DM Jr, Bahl H.

Microbiology. 2009 Jan;155(Pt 1):16-24. doi: 10.1099/mic.0.022756-0.

40.

Reductive dioxygen scavenging by flavo-diiron proteins of Clostridium acetobutylicum.

Hillmann F, Riebe O, Fischer RJ, Mot A, Caranto JD, Kurtz DM Jr, Bahl H.

FEBS Lett. 2009 Jan 5;583(1):241-5. doi: 10.1016/j.febslet.2008.12.004. Epub 2008 Dec 11.

41.

Del(6)(q22) and BCL6 rearrangements in primary CNS lymphoma are indicators of an aggressive clinical course.

Cady FM, O'Neill BP, Law ME, Decker PA, Kurtz DM, Giannini C, Porter AB, Kurtin PJ, Johnston PB, Dogan A, Remstein ED.

J Clin Oncol. 2008 Oct 10;26(29):4814-9. doi: 10.1200/JCO.2008.16.1455. Epub 2008 Jul 21.

42.

"Iron priming" guides folding of denatured aporubredoxins.

Bonomi F, Iametti S, Ferranti P, Kurtz DM Jr, Morleo A, Ragg EM.

J Biol Inorg Chem. 2008 Aug;13(6):981-91. doi: 10.1007/s00775-008-0385-4. Epub 2008 Apr 30.

43.

Clinical review: Insulin sensitizers for the treatment of hirsutism: a systematic review and metaanalyses of randomized controlled trials.

Cosma M, Swiglo BA, Flynn DN, Kurtz DM, Labella ML, Mullan RJ, Elamin MB, Erwin PJ, Montori VM.

J Clin Endocrinol Metab. 2008 Apr;93(4):1135-42. doi: 10.1210/jc.2007-2429. Epub 2008 Feb 5. Review.

PMID:
18252787
44.

Clinical review: Antiandrogens for the treatment of hirsutism: a systematic review and metaanalyses of randomized controlled trials.

Swiglo BA, Cosma M, Flynn DN, Kurtz DM, Labella ML, Mullan RJ, Erwin PJ, Montori VM.

J Clin Endocrinol Metab. 2008 Apr;93(4):1153-60. doi: 10.1210/jc.2007-2430. Epub 2008 Feb 5. Review.

PMID:
18252786
45.

Ultrasound-based transient elastography for the detection of hepatic fibrosis: systematic review and meta-analysis.

Talwalkar JA, Kurtz DM, Schoenleber SJ, West CP, Montori VM.

Clin Gastroenterol Hepatol. 2007 Oct;5(10):1214-20. Review.

PMID:
17916549
46.

Reaction of Desulfovibrio vulgaris two-iron superoxide reductase with superoxide: insights from stopped-flow spectrophotometry.

Huang VW, Emerson JP, Kurtz DM Jr.

Biochemistry. 2007 Oct 9;46(40):11342-51. Epub 2007 Sep 14.

PMID:
17854204
47.

Subcutaneous interleukin-4 (IL-4) for relapsed and resistant non-Hodgkin lymphoma: a phase II trial in the North Central Cancer Treatment Group, NCCTG 91-78-51.

Kurtz DM, Tschetter LK, Allred JB, Geyer SM, Kurtin PJ, Putnam WD, Rowland KM Jr, Wiesenfeld M, Soori GS, Tenglin RC, Bernath AM, Witzig TE.

Leuk Lymphoma. 2007 Jul;48(7):1290-8.

PMID:
17613756
48.

Comparing the electronic properties of the low-spin cyano-ferric [Fe(N4)(Cys)] active sites of superoxide reductase and p450cam using ENDOR spectroscopy and DFT calculations.

Yang TC, McNaughton RL, Clay MD, Jenney FE Jr, Krishnan R, Kurtz DM Jr, Adams MW, Johnson MK, Hoffman BM.

J Am Chem Soc. 2006 Dec 27;128(51):16566-78.

PMID:
17177406
49.

Roles of the host oxidative immune response and bacterial antioxidant rubrerythrin during Porphyromonas gingivalis infection.

Mydel P, Takahashi Y, Yumoto H, Sztukowska M, Kubica M, Gibson FC 3rd, Kurtz DM Jr, Travis J, Collins LV, Nguyen KA, Genco CA, Potempa J.

PLoS Pathog. 2006 Jul;2(7):e76.

50.

Structural basis for O2 sensing by the hemerythrin-like domain of a bacterial chemotaxis protein: substrate tunnel and fluxional N terminus.

Isaza CE, Silaghi-Dumitrescu R, Iyer RB, Kurtz DM Jr, Chan MK.

Biochemistry. 2006 Aug 1;45(30):9023-31.

PMID:
16866347

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