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Items: 6


MEK1/2 inhibition enhances the radiosensitivity of cancer cells by downregulating survival and growth signals mediated by EGFR ligands.

Chung EJ, Urick ME, Kurshan N, Shield W 3rd, Asano H, Smith PD, Scroggins BS, Burkeen J, Citrin DE.

Int J Oncol. 2013 Jun;42(6):2028-36. doi: 10.3892/ijo.2013.1890. Epub 2013 Apr 10.


Insulin-mediated acceleration of breast cancer development and progression in a nonobese model of type 2 diabetes.

Novosyadlyy R, Lann DE, Vijayakumar A, Rowzee A, Lazzarino DA, Fierz Y, Carboni JM, Gottardis MM, Pennisi PA, Molinolo AA, Kurshan N, Mejia W, Santopietro S, Yakar S, Wood TL, LeRoith D.

Cancer Res. 2010 Jan 15;70(2):741-51. doi: 10.1158/0008-5472.CAN-09-2141. Epub 2010 Jan 12.


Physical and functional interaction between polyoma virus middle T antigen and insulin and IGF-I receptors is required for oncogene activation and tumour initiation.

Novosyadlyy R, Vijayakumar A, Lann D, Fierz Y, Kurshan N, LeRoith D.

Oncogene. 2009 Oct 1;28(39):3477-86. doi: 10.1038/onc.2009.209. Epub 2009 Jul 20.


Insulin-like growth factor-I protects cells from ER stress-induced apoptosis via enhancement of the adaptive capacity of endoplasmic reticulum.

Novosyadlyy R, Kurshan N, Lann D, Vijayakumar A, Yakar S, LeRoith D.

Cell Death Differ. 2008 Aug;15(8):1304-17. doi: 10.1038/cdd.2008.52. Epub 2008 Apr 25.


Increased tumor growth in mice with diet-induced obesity: impact of ovarian hormones.

Yakar S, Nunez NP, Pennisi P, Brodt P, Sun H, Fallavollita L, Zhao H, Scavo L, Novosyadlyy R, Kurshan N, Stannard B, East-Palmer J, Smith NC, Perkins SN, Fuchs-Young R, Barrett JC, Hursting SD, LeRoith D.

Endocrinology. 2006 Dec;147(12):5826-34. Epub 2006 Sep 7.


Oral contraceptives and mood in women with and without premenstrual dysphoria: a theoretical model.

Kurshan N, Neill Epperson C.

Arch Womens Ment Health. 2006 Jan;9(1):1-14. Epub 2005 Oct 5. Review.


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