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Synthesis, in vitro and in silico evaluation of diaryl heptanones as potential 5LOX enzyme inhibitors.

Meka B, Ravada SR, Muthyala MKK, Kurre PN, Golakoti T.

Bioorg Chem. 2018 Oct;80:408-421. doi: 10.1016/j.bioorg.2018.06.015. Epub 2018 Jun 8.


Identification of N-Benzylated Indole Mannich Bases as Potential Anti TB Agents by Using Computational Studies and Molecular Hybridization Technique.

Kumar Muthyala MK, Jamullamudi RN, Sangeeta GPV, Kurre PN.

Curr Comput Aided Drug Des. 2018;14(3):200-206. doi: 10.2174/1573409914666180423093049.


Advances, challenges, and opportunities in extracellular RNA biology: insights from the NIH exRNA Strategic Workshop.

Li K, Rodosthenous RS, Kashanchi F, Gingeras T, Gould SJ, Kuo LS, Kurre P, Lee H, Leonard JN, Liu H, Lombo TB, Momma S, Nolan JP, Ochocinska MJ, Pegtel DM, Sadovsky Y, Sánchez-Madrid F, Valdes KM, Vickers KC, Weaver AM, Witwer KW, Zeng Y, Das S, Raffai RL, Howcroft TK.

JCI Insight. 2018 Apr 5;3(7). pii: 98942. doi: 10.1172/jci.insight.98942. [Epub ahead of print] Review.


Extracellular vesicles in the hematopoietic microenvironment.

Butler JT, Abdelhamed S, Kurre P.

Haematologica. 2018 Mar;103(3):382-394. doi: 10.3324/haematol.2017.183335. Epub 2018 Feb 8. Review.


Hematopoietic development: a gap in our understanding of inherited bone marrow failure.

Kurre P.

Exp Hematol. 2018 Mar;59:1-8. doi: 10.1016/j.exphem.2017.12.003. Epub 2017 Dec 15. Review.


Concise Review: Adaptation of the Bone Marrow Stroma in Hematopoietic Malignancies: Current Concepts and Models.

Doron B, Handu M, Kurre P.

Stem Cells. 2018 Mar;36(3):304-312. doi: 10.1002/stem.2761. Epub 2018 Jan 1. Review.


Understanding the bone marrow microenvironment in hematologic malignancies: A focus on chemokine, integrin, and extracellular vesicle signaling.

Sison EAR, Kurre P, Kim YM.

Pediatr Hematol Oncol. 2017 Sep - Oct;34(6-7):365-378. doi: 10.1080/08880018.2017.1395938. Epub 2017 Dec 6. Review.


Mesenchymal stromal cell-derived extracellular vesicles promote myeloid-biased multipotent hematopoietic progenitor expansion via Toll-like receptor engagement.

Goloviznina NA, Verghese SC, Yoon YM, Taratula O, Marks DL, Kurre P.

J Biol Chem. 2017 Feb 24;292(8):3541. doi: 10.1074/jbc.A116.745653. No abstract available.


IFPA meeting 2016 workshop report I: Genomic communication, bioinformatics, trophoblast biology and transport systems.

Albrecht C, Baker JC, Blundell C, Chavez SL, Carbone L, Chamley L, Hannibal RL, Illsley N, Kurre P, Laurent LC, McKenzie C, Morales-Prieto D, Pantham P, Paquette A, Powell K, Price N, Rao BM, Sadovsky Y, Salomon C, Tuteja G, Wilson S, O'Tierney-Ginn PF.

Placenta. 2017 Dec;60 Suppl 1:S5-S9. doi: 10.1016/j.placenta.2017.01.103. Epub 2017 Jan 11. Review.


Anchored Lentiviral Vector Episomes for Stem Cell Gene Therapy in Fanconi Anemia.

Verghese SC, Kurre P.

Curr Gene Ther. 2017;16(5):329-337. doi: 10.2174/1566523217666170113165407. Review.


Phenotypic correction of Fanconi anemia cells in the murine bone marrow after carrier cell mediated delivery of lentiviral vector.

Chakkaramakkil Verghese S, Goloviznina NA, Kurre P.

Stem Cell Res Ther. 2016 Nov 19;7(1):170.


Mesenchymal Stromal Cell-derived Extracellular Vesicles Promote Myeloid-biased Multipotent Hematopoietic Progenitor Expansion via Toll-Like Receptor Engagement.

Goloviznina NA, Verghese SC, Yoon YM, Taratula O, Marks DL, Kurre P.

J Biol Chem. 2016 Nov 18;291(47):24607-24617. Epub 2016 Oct 7. Erratum in: J Biol Chem. 2017 Feb 24;292(8):3541.


Endogenous DNA Damage Leads to p53-Independent Deficits in Replicative Fitness in Fetal Murine Fancd2-/- Hematopoietic Stem and Progenitor Cells.

Yoon YM, Storm KJ, Kamimae-Lanning AN, Goloviznina NA, Kurre P.

Stem Cell Reports. 2016 Nov 8;7(5):840-853. doi: 10.1016/j.stemcr.2016.09.005. Epub 2016 Oct 6.


AML suppresses hematopoiesis by releasing exosomes that contain microRNAs targeting c-MYB.

Hornick NI, Doron B, Abdelhamed S, Huan J, Harrington CA, Shen R, Cambronne XA, Chakkaramakkil Verghese S, Kurre P.

Sci Signal. 2016 Sep 6;9(444):ra88. doi: 10.1126/scisignal.aaf2797.


Hope and hype surrounding circulating microRNA as potential next generation AML biomarkers.

Abdelhamed S, Kurre P.

Leuk Res. 2015 Dec;39(12):1309-11. doi: 10.1016/j.leukres.2015.09.018. Epub 2015 Sep 21. No abstract available.


Coordinate regulation of residual bone marrow function by paracrine trafficking of AML exosomes.

Huan J, Hornick NI, Goloviznina NA, Kamimae-Lanning AN, David LL, Wilmarth PA, Mori T, Chevillet JR, Narla A, Roberts CT Jr, Loriaux MM, Chang BH, Kurre P.

Leukemia. 2015 Dec;29(12):2285-95. doi: 10.1038/leu.2015.163. Epub 2015 Jun 25.


Alterations in acute myeloid leukaemia bone marrow stromal cell exosome content coincide with gains in tyrosine kinase inhibitor resistance.

Viola S, Traer E, Huan J, Hornick NI, Tyner JW, Agarwal A, Loriaux M, Johnstone B, Kurre P.

Br J Haematol. 2016 Mar;172(6):983-6. doi: 10.1111/bjh.13551. Epub 2015 Jun 11. No abstract available.


Serum Exosome MicroRNA as a Minimally-Invasive Early Biomarker of AML.

Hornick NI, Huan J, Doron B, Goloviznina NA, Lapidus J, Chang BH, Kurre P.

Sci Rep. 2015 Jun 12;5:11295. doi: 10.1038/srep11295.


Self-enforcing feedback activation between BCL6 and pre-B cell receptor signaling defines a distinct subtype of acute lymphoblastic leukemia.

Geng H, Hurtz C, Lenz KB, Chen Z, Baumjohann D, Thompson S, Goloviznina NA, Chen WY, Huan J, LaTocha D, Ballabio E, Xiao G, Lee JW, Deucher A, Qi Z, Park E, Huang C, Nahar R, Kweon SM, Shojaee S, Chan LN, Yu J, Kornblau SM, Bijl JJ, Ye BH, Ansel KM, Paietta E, Melnick A, Hunger SP, Kurre P, Tyner JW, Loh ML, Roeder RG, Druker BJ, Burger JA, Milne TA, Chang BH, Müschen M.

Cancer Cell. 2015 Mar 9;27(3):409-25. doi: 10.1016/j.ccell.2015.02.003.


Maternal high-fat diet and obesity compromise fetal hematopoiesis.

Kamimae-Lanning AN, Krasnow SM, Goloviznina NA, Zhu X, Roth-Carter QR, Levasseur PR, Jeng S, McWeeney SK, Kurre P, Marks DL.

Mol Metab. 2014 Nov 18;4(1):25-38. doi: 10.1016/j.molmet.2014.11.001. eCollection 2015 Jan.


Orthopaedic care coordination for the intellectually and developmentally disabled adult in the residential care setting: a perfect storm.

Kurre PA.

Orthop Nurs. 2014 Sep-Oct;33(5):251-4; quiz 255-6. doi: 10.1097/NOR.0000000000000080.


Pearson marrow pancreas syndrome in patients suspected to have Diamond-Blackfan anemia.

Gagne KE, Ghazvinian R, Yuan D, Zon RL, Storm K, Mazur-Popinska M, Andolina L, Bubala H, Golebiowska S, Higman MA, Kalwak K, Kurre P, Matysiak M, Niewiadomska E, Pels S, Petruzzi MJ, Pobudejska-Pieniazek A, Szczepanski T, Fleming MD, Gazda HT, Agarwal S.

Blood. 2014 Jul 17;124(3):437-40. doi: 10.1182/blood-2014-01-545830. Epub 2014 Apr 15.


S/MAR sequence confers long-term mitotic stability on non-integrating lentiviral vector episomes without selection.

Verghese SC, Goloviznina NA, Skinner AM, Lipps HJ, Kurre P.

Nucleic Acids Res. 2014 Apr;42(7):e53. doi: 10.1093/nar/gku082. Epub 2014 Jan 27.


Cell-cell transmission of VSV-G pseudotyped lentivector particles.

Skinner AM, Chakkaramakkil Verghese S, Kurre P.

PLoS One. 2013 Sep 10;8(9):e74925. doi: 10.1371/journal.pone.0074925. eCollection 2013.


Vesicle trafficking and RNA transfer add complexity and connectivity to cell-cell communication.

Roberts CT Jr, Kurre P.

Cancer Res. 2013 Jun 1;73(11):3200-5. doi: 10.1158/0008-5472.CAN-13-0265. Epub 2013 May 21. Review.


Fetal origins of hematopoietic failure in a murine model of Fanconi anemia.

Kamimae-Lanning AN, Goloviznina NA, Kurre P.

Blood. 2013 Mar 14;121(11):2008-12. doi: 10.1182/blood-2012-06-439679. Epub 2013 Jan 11.


RNA trafficking by acute myelogenous leukemia exosomes.

Huan J, Hornick NI, Shurtleff MJ, Skinner AM, Goloviznina NA, Roberts CT Jr, Kurre P.

Cancer Res. 2013 Jan 15;73(2):918-29. doi: 10.1158/0008-5472.CAN-12-2184. Epub 2012 Nov 13.


L-Leucine alleviates Diamond-Blackfan anemia.

Kamimae-Lanning AN, Kurre P.

Blood. 2012 Sep 13;120(11):2157-8. doi: 10.1182/blood-2012-07-443978. No abstract available.


Immune markers of disease severity and treatment response in pediatric acquired aplastic anemia.

Sutton KS, Shereck EB, Nemecek ER, Kurre P.

Pediatr Blood Cancer. 2013 Mar;60(3):455-60. doi: 10.1002/pbc.24247. Epub 2012 Jul 18.


Programmed vesicle transfer of green fluorescent protein from a stably transduced cell line to primary hematopoietic cells.

Russell TB, Skinner AM, Kurre P.

Blood. 2012 May 31;119(22):5330-2. doi: 10.1182/blood-2012-04-422477. No abstract available.


Intra-hematopoietic cell fusion as a source of somatic variation in the hematopoietic system.

Skinner AM, Grompe M, Kurre P.

J Cell Sci. 2012 Jun 15;125(Pt 12):2837-43. doi: 10.1242/jcs.100123. Epub 2012 Mar 5.


Costs and consequences of immunosuppressive therapy in children with aplastic anemia.

Shereck EB, Deyell RJ, Kurre P.

Haematologica. 2011 Jun;96(6):793-5. doi: 10.3324/haematol.2011.044917. No abstract available.


Double-negative T cells are non-ALPS-specific markers of immune dysregulation found in patients with aplastic anemia.

Russell TB, Kurre P.

Blood. 2010 Dec 2;116(23):5072-3. doi: 10.1182/blood-2010-09-306910. No abstract available.


Treatment of Fanconi anemia patients using fludarabine and low-dose TBI, followed by unrelated donor hematopoietic cell transplantation.

Thakar MS, Kurre P, Storb R, Kletzel M, Frangoul H, Pulsipher MA, Leisenring W, Flowers ME, Sandmaier BM, Woolfrey A, Kiem HP.

Bone Marrow Transplant. 2011 Apr;46(4):539-44. doi: 10.1038/bmt.2010.154. Epub 2010 Jun 28.


Entry kinetics and cell-cell transmission of surface-bound retroviral vector particles.

O'Neill LS, Skinner AM, Woodward JA, Kurre P.

J Gene Med. 2010 May;12(5):463-76. doi: 10.1002/jgm.1458.


Paroxysmal nocturnal haemoglobinuria clones are part of the immune dysregulation in hepatitis-associated aplastic anaemia.

Russell TB, Eroglu Y, Zhang Z, Kurre P.

Aliment Pharmacol Ther. 2010 Jan;31(1):164-5. doi: 10.1111/j.1365-2036.2009.04114.x. No abstract available.


Genetic correction of hematopoiesis in Fanconi anemia: the case for a non-HSC-autonomous defect.

Skinner AM, Kurre P.

Mol Ther. 2009 Aug;17(8):1313-5. doi: 10.1038/mt.2009.138. No abstract available.


Cellular microvesicle pathways can be targeted to transfer genetic information between non-immune cells.

Skinner AM, O'Neill SL, Kurre P.

PLoS One. 2009 Jul 13;4(7):e6219. doi: 10.1371/journal.pone.0006219.


CXCR4 but not CXCR7 is mainly implicated in ocular leukocyte trafficking during ovalbumin-induced acute uveitis.

Zhang Z, Zhong W, Hall MJ, Kurre P, Spencer D, Skinner A, O'Neill S, Xia Z, Rosenbaum JT.

Exp Eye Res. 2009 Oct;89(4):522-31. doi: 10.1016/j.exer.2009.05.012. Epub 2009 Jun 12.


Is hematopoietic stem cell homing deficient in Fanconi anemia?

O'Neill L, Skinner AM, Kurre P.

Blood. 2009 May 21;113(21):5361; author reply 5362. doi: 10.1182/blood-2008-12-192724. No abstract available.


MRI findings in aplastic anemia.

De Mola RL, Kurre P.

Am J Hematol. 2009 Nov;84(11):754. doi: 10.1002/ajh.21394. No abstract available.


The evolving spectrum of 'non-classical' Diamond-Blackfan anaemia--a case of eADA positive pancytopenia in a young adult.

Anur P, Nemecek ER, Kurre P.

Br J Haematol. 2009 May;145(3):428-30. doi: 10.1111/j.1365-2141.2009.07590.x. Epub 2009 Feb 4. No abstract available.


Avoiding lentiviral transduction culture induced MSC senescence.

Pan YW, Kurre P.

J Cell Mol Med. 2009 Jun;13(6):1186-7. doi: 10.1111/j.1582-4934.2008.00651.x. Epub 2009 Jan 14. No abstract available.


Metachronous manifestations of Sweet's syndrome in a neutropenic patient with Fanconi anemia.

Chatham-Stephens K, Devere T, Guzman-Cottrill J, Kurre P.

Pediatr Blood Cancer. 2008 Jul;51(1):128-30. doi: 10.1002/pbc.21538.


CXCR4 induction in hematopoietic progenitor cells from Fanca(-/-), -c(-/-), and -d2(-/-) mice.

Skinner AM, O'Neill SL, Grompe M, Kurre P.

Exp Hematol. 2008 Mar;36(3):273-82. doi: 10.1016/j.exphem.2007.11.006.


Multiarm high-throughput integration site detection: limitations of LAM-PCR technology and optimization for clonal analysis.

Harkey MA, Kaul R, Jacobs MA, Kurre P, Bovee D, Levy R, Blau CA.

Stem Cells Dev. 2007 Jun;16(3):381-92.


Synthesis and in vitro anti-HIV activities of didanosine prodrugs.

Sriram D, Yogeeswari P, Babu NR, Kurre PN.

J Enzyme Inhib Med Chem. 2007 Feb;22(1):51-5.


Diagnosis and treatment of children with aplastic anemia.

Kurre P, Johnson FL, Deeg HJ.

Pediatr Blood Cancer. 2005 Nov;45(6):770-80. Review.


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