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Items: 1 to 50 of 226

1.

Association of calciprotein particles measured by a new method with coronary artery plaque in patients with coronary artery disease: A cross-sectional study.

Nakazato J, Hoshide S, Wake M, Miura Y, Kuro-O M, Kario K.

J Cardiol. 2019 May 15. pii: S0914-5087(19)30115-7. doi: 10.1016/j.jjcc.2019.04.008. [Epub ahead of print]

PMID:
31101573
2.

Signaling pathways involved in vascular smooth muscle cell calcification during hyperphosphatemia.

Voelkl J, Lang F, Eckardt KU, Amann K, Kuro-O M, Pasch A, Pieske B, Alesutan I.

Cell Mol Life Sci. 2019 Jun;76(11):2077-2091. doi: 10.1007/s00018-019-03054-z. Epub 2019 Mar 18. Review.

3.

Phosphate binding by sucroferric oxyhydroxide ameliorates renal injury in the remnant kidney model.

Nemoto Y, Kumagai T, Ishizawa K, Miura Y, Shiraishi T, Morimoto C, Sakai K, Omizo H, Yamazaki O, Tamura Y, Fujigaki Y, Kawachi H, Kuro-O M, Uchida S, Shibata S.

Sci Rep. 2019 Feb 11;9(1):1732. doi: 10.1038/s41598-018-38389-3.

4.

[Mineral metabolism and aging.]

Kuro-O M.

Clin Calcium. 2019;29(2):165-170. doi: 10.20837/4201902165. Japanese.

PMID:
30679396
5.

Fibroblast growth factor-23 promotes rhythm alterations and contractile dysfunction in adult ventricular cardiomyocytes.

Navarro-García JA, Delgado C, Fernández-Velasco M, Val-Blasco A, Rodríguez-Sánchez E, Aceves-Ripoll J, Gómez-Hurtado N, Bada-Bosch T, Mérida-Herrero E, Hernández E, Praga M, Salguero R, Solís J, Arribas F, Delgado JF, Bueno H, Kuro-O M, Ruilope LM, Ruiz-Hurtado G.

Nephrol Dial Transplant. 2019 Jan 9. doi: 10.1093/ndt/gfy392. [Epub ahead of print]

PMID:
30629224
6.

Klotho deficiency aggravates sepsis-related multiple organ dysfunction.

Jorge LB, Coelho FO, Sanches TR, Malheiros DMAC, Ezaquiel de Souza L, Dos Santos F, de Sá Lima L, Scavone C, Irigoyen M, Kuro-O M, Andrade L.

Am J Physiol Renal Physiol. 2019 Mar 1;316(3):F438-F448. doi: 10.1152/ajprenal.00625.2017. Epub 2018 Dec 5.

PMID:
30516423
7.

The Klotho proteins in health and disease.

Kuro-O M.

Nat Rev Nephrol. 2019 Jan;15(1):27-44. doi: 10.1038/s41581-018-0078-3. Review.

PMID:
30455427
8.

The Body-wide Transcriptome Landscape of Disease Models.

Kozawa S, Ueda R, Urayama K, Sagawa F, Endo S, Shiizaki K, Kurosu H, Maria de Almeida G, Hasan SM, Nakazato K, Ozaki S, Yamashita Y, Kuro-O M, Sato TN.

iScience. 2018 Apr 27;2:238-268. doi: 10.1016/j.isci.2018.03.014. Epub 2018 Mar 29.

9.
10.

Ldlr-/- and ApoE-/- mice better mimic the human metabolite signature of increased carotid intima media thickness compared to other animal models of cardiovascular disease.

Saulnier-Blache JS, Wilson R, Klavins K, Graham D, Alesutan I, Kastenmüller G, Wang-Sattler R, Adamski J, Roden M, Rathmann W, Seissler J, Meisinger C, Koenig W, Thiery J, Suhre K, Peters A, Kuro-O M, Lang F, Dallmann G, Delles C, Voelkl J, Waldenberger M, Bascands JL, Klein J, Schanstra JP.

Atherosclerosis. 2018 Sep;276:140-147. doi: 10.1016/j.atherosclerosis.2018.07.024. Epub 2018 Jul 21.

PMID:
30059845
11.

Molecular Mechanisms Underlying Accelerated Aging by Defects in the FGF23-Klotho System.

Kuro-O M.

Int J Nephrol. 2018 May 21;2018:9679841. doi: 10.1155/2018/9679841. eCollection 2018. Review.

12.

Klotho and endocrine fibroblast growth factors: markers of chronic kidney disease progression and cardiovascular complications?

Kuro-O M.

Nephrol Dial Transplant. 2019 Jan 1;34(1):15-21. doi: 10.1093/ndt/gfy126.

PMID:
29800324
13.

Fibulin-7, a heparin binding matricellular protein, promotes renal tubular calcification in mice.

Tsunezumi J, Sugiura H, Oinam L, Ali A, Thang BQ, Sada A, Yamashiro Y, Kuro-O M, Yanagisawa H.

Matrix Biol. 2018 Dec;74:5-20. doi: 10.1016/j.matbio.2018.04.014. Epub 2018 May 3.

PMID:
29730503
14.

The impact of preserved Klotho gene expression on antioxidative stress activity in healthy kidney.

Kimura T, Shiizaki K, Akimoto T, Shinzato T, Shimizu T, Kurosawa A, Kubo T, Nanmoku K, Kuro-O M, Yagisawa T.

Am J Physiol Renal Physiol. 2018 Aug 1;315(2):F345-F352. doi: 10.1152/ajprenal.00486.2017. Epub 2018 Apr 25.

15.

Zinc Inhibits Phosphate-Induced Vascular Calcification through TNFAIP3-Mediated Suppression of NF-κB.

Voelkl J, Tuffaha R, Luong TTD, Zickler D, Masyout J, Feger M, Verheyen N, Blaschke F, Kuro-O M, Tomaschitz A, Pilz S, Pasch A, Eckardt KU, Scherberich JE, Lang F, Pieske B, Alesutan I.

J Am Soc Nephrol. 2018 Jun;29(6):1636-1648. doi: 10.1681/ASN.2017050492. Epub 2018 Apr 13.

16.

PTH, vitamin D, and the FGF-23-klotho axis and heart: Going beyond the confines of nephrology.

Navarro-García JA, Fernández-Velasco M, Delgado C, Delgado JF, Kuro-O M, Ruilope LM, Ruiz-Hurtado G.

Eur J Clin Invest. 2018 Apr;48(4). doi: 10.1111/eci.12902. Epub 2018 Feb 21. Review.

PMID:
29394451
17.

Ageing-related receptors resolved.

Kuro-O M.

Nature. 2018 Jan 25;553(7689):409-410. doi: 10.1038/d41586-017-09032-4. No abstract available.

PMID:
29368738
18.

Chronic nicotine exposure reduces klotho expression and triggers different renal and hemodynamic responses in klotho-haploinsufficient mice.

Coelho FO, Jorge LB, de Bragança Viciana AC, Sanches TR, Dos Santos F, Helou CMB, Irigoyen MC, Kuro-O M, Andrade L.

Am J Physiol Renal Physiol. 2018 May 1;314(5):F992-F998. doi: 10.1152/ajprenal.00442.2016. Epub 2018 Jan 24.

19.

Identification and quantification of plasma calciprotein particles with distinct physical properties in patients with chronic kidney disease.

Miura Y, Iwazu Y, Shiizaki K, Akimoto T, Kotani K, Kurabayashi M, Kurosu H, Kuro-O M.

Sci Rep. 2018 Jan 19;8(1):1256. doi: 10.1038/s41598-018-19677-4.

20.

Novel treatment strategies for chronic kidney disease: insights from the animal kingdom.

Stenvinkel P, Painer J, Kuro-O M, Lanaspa M, Arnold W, Ruf T, Shiels PG, Johnson RJ.

Nat Rev Nephrol. 2018 Apr;14(4):265-284. doi: 10.1038/nrneph.2017.169. Epub 2018 Jan 15. Review.

PMID:
29332935
21.

Macrophages escape Klotho gene silencing in the mdx mouse model of Duchenne muscular dystrophy and promote muscle growth and increase satellite cell numbers through a Klotho-mediated pathway.

Wehling-Henricks M, Welc SS, Samengo G, Rinaldi C, Lindsey C, Wang Y, Lee J, Kuro-O M, Tidball JG.

Hum Mol Genet. 2018 Jan 1;27(1):14-29. doi: 10.1093/hmg/ddx380.

22.

Enpp1 is an anti-aging factor that regulates Klotho under phosphate overload conditions.

Watanabe R, Fujita N, Sato Y, Kobayashi T, Morita M, Oike T, Miyamoto K, Kuro-O M, Michigami T, Fukumoto S, Tsuji T, Toyama Y, Nakamura M, Matsumoto M, Miyamoto T.

Sci Rep. 2017 Aug 10;7(1):7786. doi: 10.1038/s41598-017-07341-2.

23.

Association between circulating fibroblast growth factor 21 and mortality in end-stage renal disease.

Kohara M, Masuda T, Shiizaki K, Akimoto T, Watanabe Y, Honma S, Sekiguchi C, Miyazawa Y, Kusano E, Kanda Y, Asano Y, Kuro-O M, Nagata D.

PLoS One. 2017 Jun 5;12(6):e0178971. doi: 10.1371/journal.pone.0178971. eCollection 2017.

24.

Involvement Of Vascular Aldosterone Synthase In Phosphate-Induced Osteogenic Transformation Of Vascular Smooth Muscle Cells.

Alesutan I, Voelkl J, Feger M, Kratschmar DV, Castor T, Mia S, Sacherer M, Viereck R, Borst O, Leibrock C, Gawaz M, Kuro-O M, Pilz S, Tomaschitz A, Odermatt A, Pieske B, Wagner CA, Lang F.

Sci Rep. 2017 May 17;7(1):2059. doi: 10.1038/s41598-017-01882-2.

25.

Differential regulation of renal Klotho and FGFR1 in normal and uremic rats.

Muñoz-Castañeda JR, Herencia C, Pendón-Ruiz de Mier MV, Rodriguez-Ortiz ME, Diaz-Tocados JM, Vergara N, Martínez-Moreno JM, Salmerón MD, Richards WG, Felsenfeld A, Kuro-O M, Almadén Y, Rodríguez M.

FASEB J. 2017 Sep;31(9):3858-3867. doi: 10.1096/fj.201700006R. Epub 2017 May 17.

PMID:
28515153
26.

Fibroblast growth factor 21, assisted by elevated glucose, activates paraventricular nucleus NUCB2/Nesfatin-1 neurons to produce satiety under fed states.

Santoso P, Nakata M, Shiizaki K, Boyang Z, Parmila K, Otgon-Uul Z, Hashimoto K, Satoh T, Mori M, Kuro-O M, Yada T.

Sci Rep. 2017 Apr 4;7:45819. doi: 10.1038/srep45819.

27.

Recombinant α-Klotho may be prophylactic and therapeutic for acute to chronic kidney disease progression and uremic cardiomyopathy.

Hu MC, Shi M, Gillings N, Flores B, Takahashi M, Kuro-O M, Moe OW.

Kidney Int. 2017 May;91(5):1104-1114. doi: 10.1016/j.kint.2016.10.034. Epub 2017 Jan 25.

28.

Persistent fibroblast growth factor 23 signalling in the parathyroid glands for secondary hyperparathyroidism in mice with chronic kidney disease.

Kawakami K, Takeshita A, Furushima K, Miyajima M, Hatamura I, Kuro-O M, Furuta Y, Sakaguchi K.

Sci Rep. 2017 Jan 17;7:40534. doi: 10.1038/srep40534.

29.

Daily variability in serum levels of calciprotein particles and their association with mineral metabolism parameters: A cross-sectional pilot study.

Yamada H, Kuro-O M, Ishikawa SE, Funazaki S, Kusaka I, Kakei M, Hara K.

Nephrology (Carlton). 2018 Mar;23(3):226-230. doi: 10.1111/nep.12994.

PMID:
28052525
30.

FGF23-αKlotho as a paradigm for a kidney-bone network.

Kuro-O M, Moe OW.

Bone. 2017 Jul;100:4-18. doi: 10.1016/j.bone.2016.11.013. Epub 2016 Nov 12. Review.

PMID:
27847255
31.

The FGF23 and Klotho system beyond mineral metabolism.

Kuro-O M.

Clin Exp Nephrol. 2017 Mar;21(Suppl 1):64-69. doi: 10.1007/s10157-016-1357-6. Epub 2016 Nov 12. Review.

PMID:
27838783
32.

A Novel Index Using Ankle Hemodynamic Parameters to Assess the Severity of Peripheral Arterial Disease: A Pilot Study.

Tanno J, Gatate Y, Kasai T, Nakano S, Senbonmatsu T, Sato O, Ichioka S, Kuro-O M, Nishimura S.

PLoS One. 2016 Oct 19;11(10):e0164756. doi: 10.1371/journal.pone.0164756. eCollection 2016.

33.

Kotho and aging.

Kuro-O M.

Nihon Rinsho. 2016 Sep;74(9):1467-1473. Review. Japanese.

PMID:
30557478
34.

The Urinary Phosphate to Serum Fibroblast Growth Factor 23 Ratio Is a Useful Marker of Atherosclerosis in Early-Stage Chronic Kidney Disease.

Yamada H, Kuro-O M, Hara K, Ueda Y, Kusaka I, Kakei M, Ishikawa SE.

PLoS One. 2016 Aug 9;11(8):e0160782. doi: 10.1371/journal.pone.0160782. eCollection 2016.

35.

[Role of parathyroid hormone in Klotho-FGF23 system].

Kimura T, Shiizaki K, Kuro-O M.

Clin Calcium. 2016 Jun;26(6):859-66. doi: CliCa1606859866. Japanese.

PMID:
27230841
36.

Klotho gene silencing promotes pathology in the mdx mouse model of Duchenne muscular dystrophy.

Wehling-Henricks M, Li Z, Lindsey C, Wang Y, Welc SS, Ramos JN, Khanlou N, Kuro-O M, Tidball JG.

Hum Mol Genet. 2016 Jun 15;25(12):2465-2482. Epub 2016 May 6.

37.

1,25(OH)2D3 dependent overt hyperactivity phenotype in klotho-hypomorphic mice.

Leibrock CB, Voelkl J, Kuro-O M, Lang F, Lang UE.

Sci Rep. 2016 Apr 25;6:24879. doi: 10.1038/srep24879.

38.

Augmentation of phosphate-induced osteo-/chondrogenic transformation of vascular smooth muscle cells by homoarginine.

Alesutan I, Feger M, Tuffaha R, Castor T, Musculus K, Buehling SS, Heine CL, Kuro-O M, Pieske B, Schmidt K, Tomaschitz A, Maerz W, Pilz S, Meinitzer A, Voelkl J, Lang F.

Cardiovasc Res. 2016 Jun 1;110(3):408-18. doi: 10.1093/cvr/cvw062. Epub 2016 Mar 21.

PMID:
27001421
39.

Phosphate-Induced Renal Fibrosis Requires the Prolyl Isomerase Pin1.

Shen ZJ, Hu J, Shiizaki K, Kuro-o M, Malter JS.

PLoS One. 2016 Feb 25;11(2):e0150093. doi: 10.1371/journal.pone.0150093. eCollection 2016.

40.

Partial Reversal of Tissue Calcification and Extension of Life Span following Ammonium Nitrate Treatment of Klotho-Deficient Mice.

Leibrock CB, Feger M, Voelkl J, Kohlhofer U, Quintanilla-Martinez L, Kuro-o M, Lang F.

Kidney Blood Press Res. 2016;41(1):99-107. doi: 10.1159/000443411. Epub 2016 Feb 16.

41.

αKlotho deficiency in acute kidney injury contributes to lung damage.

Ravikumar P, Li L, Ye J, Shi M, Taniguchi M, Zhang J, Kuro-o M, Hu MC, Moe OW, Hsia CC.

J Appl Physiol (1985). 2016 Apr 1;120(7):723-32. doi: 10.1152/japplphysiol.00792.2015. Epub 2015 Dec 30.

42.

Association between Serum Soluble Klotho Levels and Mortality in Chronic Hemodialysis Patients.

Otani-Takei N, Masuda T, Akimoto T, Honma S, Watanabe Y, Shiizaki K, Miki T, Kusano E, Asano Y, Kuro-O M, Nagata D.

Int J Endocrinol. 2015;2015:406269. doi: 10.1155/2015/406269. Epub 2015 Oct 28.

43.

Bicarbonate-sensitive calcification and lifespan of klotho-deficient mice.

Leibrock CB, Voelkl J, Kohlhofer U, Quintanilla-Martinez L, Kuro-O M, Lang F.

Am J Physiol Renal Physiol. 2016 Jan 1;310(1):F102-8. doi: 10.1152/ajprenal.00037.2015. Epub 2015 Nov 4.

44.

Saturated phosphatidic acids mediate saturated fatty acid-induced vascular calcification and lipotoxicity.

Masuda M, Miyazaki-Anzai S, Keenan AL, Okamura K, Kendrick J, Chonchol M, Offermanns S, Ntambi JM, Kuro-O M, Miyazaki M.

J Clin Invest. 2015 Oct 26;125(12):4544-58. doi: 10.1172/JCI82871.

45.

Klotho Regulates 14-3-3ζ Monomerization and Binding to the ASK1 Signaling Complex in Response to Oxidative Stress.

Brobey RK, Dheghani M, Foster PP, Kuro-O M, Rosenblatt KP.

PLoS One. 2015 Oct 30;10(10):e0141968. doi: 10.1371/journal.pone.0141968. eCollection 2015.

46.

Soluble αKlotho as a candidate for the biomarker of aging.

Koyama D, Sato Y, Aizawa M, Maki T, Kurosawa M, Kuro-o M, Furukawa Y.

Biochem Biophys Res Commun. 2015 Nov 27;467(4):1019-25. doi: 10.1016/j.bbrc.2015.10.018. Epub 2015 Oct 14.

PMID:
26462468
47.

Klotho Protects Dopaminergic Neuron Oxidant-Induced Degeneration by Modulating ASK1 and p38 MAPK Signaling Pathways.

Brobey RK, German D, Sonsalla PK, Gurnani P, Pastor J, Hsieh CC, Papaconstantinou J, Foster PP, Kuro-o M, Rosenblatt KP.

PLoS One. 2015 Oct 9;10(10):e0139914. doi: 10.1371/journal.pone.0139914. eCollection 2015.

48.

Acetazolamide sensitive tissue calcification and aging of klotho-hypomorphic mice.

Leibrock CB, Alesutan I, Voelkl J, Michael D, Castor T, Kohlhofer U, Quintanilla-Martinez L, Kübler L, Mannheim JG, Pichler BJ, Rosenblatt KP, Kuro-o M, Lang F.

J Mol Med (Berl). 2016 Jan;94(1):95-106. doi: 10.1007/s00109-015-1331-x. Epub 2015 Aug 27.

PMID:
26307633
49.

Renal Production, Uptake, and Handling of Circulating αKlotho.

Hu MC, Shi M, Zhang J, Addo T, Cho HJ, Barker SL, Ravikumar P, Gillings N, Bian A, Sidhu SS, Kuro-o M, Moe OW.

J Am Soc Nephrol. 2016 Jan;27(1):79-90. doi: 10.1681/ASN.2014101030. Epub 2015 May 14.

50.

Up-regulation of megakaryocytic Na(+)/Ca(2+) exchange in klotho-deficient mice.

Schmid E, Yan J, Hosseinzadeh Z, Almilaji A, Shumilina E, Kuro-o M, Borst O, Gawaz M, Lang F.

Biochem Biophys Res Commun. 2015 May 1;460(2):177-82. doi: 10.1016/j.bbrc.2015.03.002. Epub 2015 Mar 10.

PMID:
25767077

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