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Items: 17

1.

Small Heat Shock Proteins, Amyloid Fibrils, and Nicotine Stimulate a Common Immune Suppressive Pathway with Implications for Future Therapies.

Rothbard JB, Kurnellas MP, Ousman SS, Brownell S, Rothbard JJ, Steinman L.

Cold Spring Harb Perspect Med. 2019 Jul 1;9(7). pii: a034223. doi: 10.1101/cshperspect.a034223. Review.

PMID:
30249602
2.

Amyloid fibrils activate B-1a lymphocytes to ameliorate inflammatory brain disease.

Kurnellas MP, Ghosn EE, Schartner JM, Baker J, Rothbard JJ, Negrin RS, Herzenberg LA, Fathman CG, Steinman L, Rothbard JB.

Proc Natl Acad Sci U S A. 2015 Dec 8;112(49):15016-23. doi: 10.1073/pnas.1521206112. Epub 2015 Nov 30.

3.

Self-Assembling Peptides Form Immune Suppressive Amyloid Fibrils Effective in Autoimmune Encephalomyelitis.

Kurnellas MP, Rothbard JB, Steinman L.

Curr Top Behav Neurosci. 2015;26:221-32. doi: 10.1007/7854_2015_377. Review.

PMID:
25981913
4.

Mechanisms of action of therapeutic amyloidogenic hexapeptides in amelioration of inflammatory brain disease.

Kurnellas MP, Schartner JM, Fathman CG, Jagger A, Steinman L, Rothbard JB.

J Exp Med. 2014 Aug 25;211(9):1847-56. doi: 10.1084/jem.20140107. Epub 2014 Jul 29.

5.

Janus faces of amyloid proteins in neuroinflammation.

Steinman L, Rothbard JB, Kurnellas MP.

J Clin Immunol. 2014 Jul;34 Suppl 1:S61-3. doi: 10.1007/s10875-014-0034-3. Epub 2014 Apr 8. Review.

6.

Amyloid fibrils composed of hexameric peptides attenuate neuroinflammation.

Kurnellas MP, Adams CM, Sobel RA, Steinman L, Rothbard JB.

Sci Transl Med. 2013 Apr 3;5(179):179ra42. doi: 10.1126/scitranslmed.3005681.

7.

Piet Mondrian's trees and the evolution in understanding multiple sclerosis, Charcot Prize Lecture 2011.

Steinman L, Axtell RC, Barbieri D, Bhat R, Brownell SE, de Jong BA, Dunn SE, Grant JL, Han MH, Ho PP, Kuipers HF, Kurnellas MP, Ousman SS, Rothbard JB.

Mult Scler. 2013 Jan;19(1):5-14. doi: 10.1177/1352458512470730.

PMID:
23303879
8.

Chaperone activity of small heat shock proteins underlies therapeutic efficacy in experimental autoimmune encephalomyelitis.

Kurnellas MP, Brownell SE, Su L, Malkovskiy AV, Rajadas J, Dolganov G, Chopra S, Schoolnik GK, Sobel RA, Webster J, Ousman SS, Becker RA, Steinman L, Rothbard JB.

J Biol Chem. 2012 Oct 19;287(43):36423-34. doi: 10.1074/jbc.M112.371229. Epub 2012 Sep 6.

9.

Therapeutic effects of systemic administration of chaperone αB-crystallin associated with binding proinflammatory plasma proteins.

Rothbard JB, Kurnellas MP, Brownell S, Adams CM, Su L, Axtell RC, Chen R, Fathman CG, Robinson WH, Steinman L.

J Biol Chem. 2012 Mar 23;287(13):9708-21. doi: 10.1074/jbc.M111.337691. Epub 2012 Feb 3.

10.

Reduced expression of plasma membrane calcium ATPase 2 and collapsin response mediator protein 1 promotes death of spinal cord neurons.

Kurnellas MP, Li H, Jain MR, Giraud SN, Nicot AB, Ratnayake A, Heary RF, Elkabes S.

Cell Death Differ. 2010 Sep;17(9):1501-10. doi: 10.1038/cdd.2010.54. Epub 2010 May 21.

11.

Reductions in motor unit number estimates (MUNE) precede motor neuron loss in the plasma membrane calcium ATPase 2 (PMCA2)-heterozygous mice.

Souayah N, Sharovetskaya A, Kurnellas MP, Myerson M, Deitch JS, Elkabes S.

Exp Neurol. 2008 Dec;214(2):341-346. doi: 10.1016/j.expneurol.2008.09.002. Epub 2008 Sep 19.

12.

Mechanisms of neuronal damage in multiple sclerosis and its animal models: role of calcium pumps and exchangers.

Kurnellas MP, Donahue KC, Elkabes S.

Biochem Soc Trans. 2007 Nov;35(Pt 5):923-6. Review.

13.

Identification of differentially expressed proteins in experimental autoimmune encephalomyelitis (EAE) by proteomic analysis of the spinal cord.

Liu T, Donahue KC, Hu J, Kurnellas MP, Grant JE, Li H, Elkabes S.

J Proteome Res. 2007 Jul;6(7):2565-75. Epub 2007 Jun 16.

14.

Role of plasma membrane calcium ATPase isoform 2 in neuronal function in the cerebellum and spinal cord.

Kurnellas MP, Lee AK, Szczepanowski K, Elkabes S.

Ann N Y Acad Sci. 2007 Mar;1099:287-91.

PMID:
17446469
15.

Molecular alterations in the cerebellum of the plasma membrane calcium ATPase 2 (PMCA2)-null mouse indicate abnormalities in Purkinje neurons.

Kurnellas MP, Lee AK, Li H, Deng L, Ehrlich DJ, Elkabes S.

Mol Cell Neurosci. 2007 Feb;34(2):178-88. Epub 2006 Dec 5.

17.

Calcium responses of chicken trigeminal ganglion neurons to methyl anthranilate and capsaicin.

Kirifides ML, Kurnellas MP, Clark L, Bryant BP.

J Exp Biol. 2004 Feb;207(Pt 5):715-22.

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