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Items: 1 to 50 of 259

1.

Amino Acid-Derived Sensors For Specific Zn2+ Detection Using Hyperpolarized 13C Magnetic Resonance Spectroscopy.

Wang S, Korenchan DE, Perez PM, Taglang C, Hayes TR, Sriram R, Bok R, Hong AS, Wu Y, Li H, Wang Z, Kurhanewicz J, Wilson D, Flavell R.

Chemistry. 2019 Jul 23. doi: 10.1002/chem.201902771. [Epub ahead of print]

PMID:
31338914
2.

Zero-field nuclear magnetic resonance of chemically exchanging systems.

Barskiy DA, Tayler MCD, Marco-Rius I, Kurhanewicz J, Vigneron DB, Cikrikci S, Aydogdu A, Reh M, Pravdivtsev AN, Hövener JB, Blanchard JW, Wu T, Budker D, Pines A.

Nat Commun. 2019 Jul 5;10(1):3002. doi: 10.1038/s41467-019-10787-9.

3.

In memoriam: Sarah J. Nelson, January 26, 1954-April 3, 2019.

Majumdar S, Lupo J, Vigneron D, Ronen S, Kurhanewicz J, Hess C.

Magn Reson Med. 2019 Oct;82(4):1255-1258. doi: 10.1002/mrm.27814. Epub 2019 May 17. No abstract available.

PMID:
31102294
4.

Using bidirectional chemical exchange for improved hyperpolarized [13 C]bicarbonate pH imaging.

Korenchan DE, Gordon JW, Subramaniam S, Sriram R, Baligand C, VanCriekinge M, Bok R, Vigneron DB, Wilson DM, Larson PEZ, Kurhanewicz J, Flavell RR.

Magn Reson Med. 2019 Sep;82(3):959-972. doi: 10.1002/mrm.27780. Epub 2019 May 3.

PMID:
31050049
5.

Measuring Dynamic Changes in the Labile Iron Pool in Vivo with a Reactivity-Based Probe for Positron Emission Tomography.

Muir RK, Zhao N, Wei J, Wang YH, Moroz A, Huang Y, Chen YC, Sriram R, Kurhanewicz J, Ruggero D, Renslo AR, Evans MJ.

ACS Cent Sci. 2019 Apr 24;5(4):727-736. doi: 10.1021/acscentsci.9b00240. Epub 2019 Apr 3.

6.

NMR quantification of lactate production and efflux and glutamate fractional enrichment in living human prostate biopsies cultured with [1,6-13 C2 ]glucose.

Bancroft Brown J, Sriram R, VanCriekinge M, Delos Santos R, Sun J, Delos Santos J, Tabatabai ZL, Shinohara K, Nguyen H, Peehl DM, Kurhanewicz J.

Magn Reson Med. 2019 Aug;82(2):566-576. doi: 10.1002/mrm.27739. Epub 2019 Mar 28.

PMID:
30924180
7.

Coil combination methods for multi-channel hyperpolarized 13C imaging data from human studies.

Zhu Z, Zhu X, Ohliger MA, Tang S, Cao P, Carvajal L, Autry AW, Li Y, Kurhanewicz J, Chang S, Aggarwal R, Munster P, Xu D, Larson PEZ, Vigneron DB, Gordon JW.

J Magn Reson. 2019 Apr;301:73-79. doi: 10.1016/j.jmr.2019.01.015. Epub 2019 Feb 1.

PMID:
30851668
8.

Hyperpolarized 13C MRI: State of the Art and Future Directions.

Wang ZJ, Ohliger MA, Larson PEZ, Gordon JW, Bok RA, Slater J, Villanueva-Meyer JE, Hess CP, Kurhanewicz J, Vigneron DB.

Radiology. 2019 May;291(2):273-284. doi: 10.1148/radiol.2019182391. Epub 2019 Mar 5.

PMID:
30835184
9.

The Role of Lactate Metabolism in Prostate Cancer Progression and Metastases Revealed by Dual-Agent Hyperpolarized 13C MRSI.

Bok R, Lee J, Sriram R, Keshari K, Sukumar S, Daneshmandi S, Korenchan DE, Flavell RR, Vigneron DB, Kurhanewicz J, Seth P.

Cancers (Basel). 2019 Feb 22;11(2). pii: E257. doi: 10.3390/cancers11020257.

10.

Pulse sequence considerations for quantification of pyruvate-to-lactate conversion kPL in hyperpolarized 13 C imaging.

Chen HY, Gordon JW, Bok RA, Cao P, von Morze C, van Criekinge M, Milshteyn E, Carvajal L, Hurd RE, Kurhanewicz J, Vigneron DB, Larson PEZ.

NMR Biomed. 2019 Mar;32(3):e4052. doi: 10.1002/nbm.4052. Epub 2019 Jan 21.

PMID:
30664305
11.

Hyperpolarized 13C MRI: Path to Clinical Translation in Oncology.

Kurhanewicz J, Vigneron DB, Ardenkjaer-Larsen JH, Bankson JA, Brindle K, Cunningham CH, Gallagher FA, Keshari KR, Kjaer A, Laustsen C, Mankoff DA, Merritt ME, Nelson SJ, Pauly JM, Lee P, Ronen S, Tyler DJ, Rajan SS, Spielman DM, Wald L, Zhang X, Malloy CR, Rizi R.

Neoplasia. 2019 Jan;21(1):1-16. doi: 10.1016/j.neo.2018.09.006. Epub 2018 Nov 23. Review.

12.

Phase I Study of CTT1057, an 18F-Labeled Imaging Agent with Phosphoramidate Core Targeting Prostate-Specific Membrane Antigen in Prostate Cancer.

Behr SC, Aggarwal R, VanBrocklin HF, Flavell RR, Gao K, Small EJ, Blecha J, Jivan S, Hope TA, Simko JP, Kurhanewicz J, Noworolski SM, Korn NJ, De Los Santos R, Cooperberg MR, Carroll PR, Nguyen HG, Greene KL, Langton-Webster B, Berkman CE, Seo Y.

J Nucl Med. 2019 Jul;60(7):910-916. doi: 10.2967/jnumed.118.220715. Epub 2018 Nov 21.

PMID:
30464040
13.

Translation of Carbon-13 EPI for hyperpolarized MR molecular imaging of prostate and brain cancer patients.

Gordon JW, Chen HY, Autry A, Park I, Van Criekinge M, Mammoli D, Milshteyn E, Bok R, Xu D, Li Y, Aggarwal R, Chang S, Slater JB, Ferrone M, Nelson S, Kurhanewicz J, Larson PEZ, Vigneron DB.

Magn Reson Med. 2019 Apr;81(4):2702-2709. doi: 10.1002/mrm.27549. Epub 2018 Oct 30.

PMID:
30375043
14.

Dynamic diffusion-weighted hyperpolarized 13 C imaging based on a slice-selective double spin echo sequence for measurements of cellular transport.

Zhu X, Gordon JW, Bok RA, Kurhanewicz J, Larson PEZ.

Magn Reson Med. 2019 Mar;81(3):2001-2010. doi: 10.1002/mrm.27501. Epub 2018 Oct 28.

PMID:
30368893
15.

Investigation of analysis methods for hyperpolarized 13C-pyruvate metabolic MRI in prostate cancer patients.

Larson PEZ, Chen HY, Gordon JW, Korn N, Maidens J, Arcak M, Tang S, Criekinge M, Carvajal L, Mammoli D, Bok R, Aggarwal R, Ferrone M, Slater JB, Nelson SJ, Kurhanewicz J, Vigneron DB.

NMR Biomed. 2018 Nov;31(11):e3997. doi: 10.1002/nbm.3997. Epub 2018 Sep 19.

PMID:
30230646
16.

Non-Invasive Assessment of Lactate Production and Compartmentalization in Renal Cell Carcinomas Using Hyperpolarized 13C Pyruvate MRI.

Sriram R, Gordon J, Baligand C, Ahamed F, Delos Santos J, Qin H, Bok RA, Vigneron DB, Kurhanewicz J, Larson PEZ, Wang ZJ.

Cancers (Basel). 2018 Sep 5;10(9). pii: E313. doi: 10.3390/cancers10090313.

17.

Phase I study of dose escalation to dominant intraprostatic lesions using high-dose-rate brachytherapy.

Chapman CH, Braunstein SE, Pouliot J, Noworolski SM, Weinberg V, Cunha A, Kurhanewicz J, Gottschalk AR, Roach MI, Hsu IC.

J Contemp Brachytherapy. 2018 Jun;10(3):193-201. doi: 10.5114/jcb.2018.76881. Epub 2018 Jun 29.

18.

Assessing high-intensity focused ultrasound treatment of prostate cancer with hyperpolarized 13 C dual-agent imaging of metabolism and perfusion.

Lee JE, Diederich CJ, Bok R, Sriram R, Santos RD, Noworolski SM, Salgaonkar VA, Adams MS, Vigneron DB, Kurhanewicz J.

NMR Biomed. 2018 Jul 18:e3962. doi: 10.1002/nbm.3962. [Epub ahead of print]

PMID:
30022550
19.

Spatio-Temporally Constrained Reconstruction for Hyperpolarized Carbon-13 MRI Using Kinetic Models.

Maidens J, Gordon JW, Chen HY, Park I, Van Criekinge M, Milshteyn E, Bok R, Aggarwal R, Ferrone M, Slater JB, Kurhanewicz J, Vigneron DB, Arcak M, Larson PEZ.

IEEE Trans Med Imaging. 2018 Dec;37(12):2603-2612. doi: 10.1109/TMI.2018.2844246. Epub 2018 Jun 5.

PMID:
29994332
20.

Phase 1 investigation of lenalidomide/rituximab plus outcomes of lenalidomide maintenance in relapsed CNS lymphoma.

Rubenstein JL, Geng H, Fraser EJ, Formaker P, Chen L, Sharma J, Killea P, Choi K, Ventura J, Kurhanewicz J, Lowell C, Hwang J, Treseler P, Sneed PK, Li J, Wang X, Chen N, Gangoiti J, Munster PN, Damato B.

Blood Adv. 2018 Jul 10;2(13):1595-1607. doi: 10.1182/bloodadvances.2017014845.

21.

Molecular detection of inflammation in cell models using hyperpolarized 13C-pyruvate.

Sriram R, Nguyen J, Santos JD, Nguyen L, Sun J, Vigneron S, Van Criekinge M, Kurhanewicz J, MacKenzie JD.

Theranostics. 2018 May 23;8(12):3400-3407. doi: 10.7150/thno.24322. eCollection 2018.

22.

Imaging glutathione depletion in the rat brain using ascorbate-derived hyperpolarized MR and PET probes.

Qin H, Carroll VN, Sriram R, Villanueva-Meyer JE, von Morze C, Wang ZJ, Mutch CA, Keshari KR, Flavell RR, Kurhanewicz J, Wilson DM.

Sci Rep. 2018 May 21;8(1):7928. doi: 10.1038/s41598-018-26296-6.

23.

Measuring glucocorticoid receptor expression in vivo with PET.

Truillet C, Parker MFL, Huynh LT, Wei J, Jami KM, Wang YH, Shen YS, Sriram R, Wilson DM, Kurhanewicz J, Evans MJ.

Oncotarget. 2018 Apr 17;9(29):20399-20408. doi: 10.18632/oncotarget.24911. eCollection 2018 Apr 17.

24.

Late-stage deuteration of 13C-enriched substrates for T1 prolongation in hyperpolarized 13C MRI.

Taglang C, Korenchan DE, von Morze C, Yu J, Najac C, Wang S, Blecha JE, Subramaniam S, Bok R, VanBrocklin HF, Vigneron DB, Ronen SM, Sriram R, Kurhanewicz J, Wilson DM, Flavell RR.

Chem Commun (Camb). 2018 May 17;54(41):5233-5236. doi: 10.1039/c8cc02246a.

25.

Technique development of 3D dynamic CS-EPSI for hyperpolarized 13 C pyruvate MR molecular imaging of human prostate cancer.

Chen HY, Larson PEZ, Gordon JW, Bok RA, Ferrone M, van Criekinge M, Carvajal L, Cao P, Pauly JM, Kerr AB, Park I, Slater JB, Nelson SJ, Munster PN, Aggarwal R, Kurhanewicz J, Vigneron DB.

Magn Reson Med. 2018 Nov;80(5):2062-2072. doi: 10.1002/mrm.27179. Epub 2018 Mar 25.

PMID:
29575178
26.

In vivo hyperpolarization transfer in a clinical MRI scanner.

von Morze C, Reed GD, Larson PE, Mammoli D, Chen AP, Tropp J, Van Criekinge M, Ohliger MA, Kurhanewicz J, Vigneron DB, Merritt ME.

Magn Reson Med. 2018 Aug;80(2):480-487. doi: 10.1002/mrm.27154. Epub 2018 Feb 27.

27.

Detection of Bacteria-Specific Metabolism Using Hyperpolarized [2-13C]Pyruvate.

Sriram R, Sun J, Villanueva-Meyer J, Mutch C, De Los Santos J, Peters J, Korenchan DE, Neumann K, Van Criekinge M, Kurhanewicz J, Rosenberg O, Wilson D, Ohliger MA.

ACS Infect Dis. 2018 May 11;4(5):797-805. doi: 10.1021/acsinfecdis.7b00234. Epub 2018 Feb 13.

28.

Non-invasive detection of divergent metabolic signals in insulin deficiency vs. insulin resistance in vivo.

Morze CV, Allu PKR, Chang GY, Marco-Rius I, Milshteyn E, Wang ZJ, Ohliger MA, Gleason CE, Kurhanewicz J, Vigneron DB, Pearce D.

Sci Rep. 2018 Feb 1;8(1):2088. doi: 10.1038/s41598-018-20264-w.

29.

Development of methods and feasibility of using hyperpolarized carbon-13 imaging data for evaluating brain metabolism in patient studies.

Park I, Larson PEZ, Gordon JW, Carvajal L, Chen HY, Bok R, Van Criekinge M, Ferrone M, Slater JB, Xu D, Kurhanewicz J, Vigneron DB, Chang S, Nelson SJ.

Magn Reson Med. 2018 Sep;80(3):864-873. doi: 10.1002/mrm.27077. Epub 2018 Jan 10. No abstract available.

PMID:
29322616
30.

Direct assessment of renal mitochondrial redox state using hyperpolarized 13 C-acetoacetate.

von Morze C, Ohliger MA, Marco-Rius I, Wilson DM, Flavell RR, Pearce D, Vigneron DB, Kurhanewicz J, Wang ZJ.

Magn Reson Med. 2018 Apr;79(4):1862-1869. doi: 10.1002/mrm.27054. Epub 2018 Jan 3.

31.

Sensitivity enhancement for detection of hyperpolarized 13 C MRI probes with 1 H spin coupling introduced by enzymatic transformation in vivo.

von Morze C, Tropp J, Chen AP, Marco-Rius I, Van Criekinge M, Skloss TW, Mammoli D, Kurhanewicz J, Vigneron DB, Ohliger MA, Merritt ME.

Magn Reson Med. 2018 Jul;80(1):36-41. doi: 10.1002/mrm.27000. Epub 2017 Nov 28.

32.

Impact of the integration of proton magnetic resonance imaging spectroscopy to PI-RADS 2 for prediction of high grade and high stage prostate cancer.

Leapman MS, Wang ZJ, Behr SC, Kurhanewicz J, Zagoria RJ, Carroll PR, Westphalen AC.

Radiol Bras. 2017 Sep-Oct;50(5):299-307. doi: 10.1590/0100-3984.2016.0117.

33.

Characterization and stratification of prostate lesions based on comprehensive multiparametric MRI using detailed whole-mount histopathology as a reference standard.

Starobinets O, Simko JP, Kuchinsky K, Kornak J, Carroll PR, Greene KL, Kurhanewicz J, Noworolski SM.

NMR Biomed. 2017 Dec;30(12). doi: 10.1002/nbm.3796. Epub 2017 Sep 29.

PMID:
28961382
34.

Unsaturation level decreased in bone marrow fat of postmenopausal women with low bone density using high resolution magic angle spinning (HRMAS) 1H NMR spectroscopy.

Li X, Shet K, Xu K, Rodríguez JP, Pino AM, Kurhanewicz J, Schwartz A, Rosen CJ.

Bone. 2017 Dec;105:87-92. doi: 10.1016/j.bone.2017.08.014. Epub 2017 Aug 18.

35.

Hyperpolarized 1-[13C]-Pyruvate Magnetic Resonance Imaging Detects an Early Metabolic Response to Androgen Ablation Therapy in Prostate Cancer.

Aggarwal R, Vigneron DB, Kurhanewicz J.

Eur Urol. 2017 Dec;72(6):1028-1029. doi: 10.1016/j.eururo.2017.07.022. Epub 2017 Jul 29. No abstract available.

36.

Cancer recurrence monitoring using hyperpolarized [1-13C]pyruvate metabolic imaging in murine breast cancer model.

Shin PJ, Zhu Z, Camarda R, Bok RA, Zhou AY, Kurhanewicz J, Goga A, Vigneron DB.

Magn Reson Imaging. 2017 Nov;43:105-109. doi: 10.1016/j.mri.2017.07.014. Epub 2017 Jul 15.

37.

Hyperpolarized 13 C magnetic resonance evaluation of renal ischemia reperfusion injury in a murine model.

Baligand C, Qin H, True-Yasaki A, Gordon JW, von Morze C, Santos JD, Wilson DM, Raffai R, Cowley PM, Baker AJ, Kurhanewicz J, Lovett DH, Wang ZJ.

NMR Biomed. 2017 Oct;30(10). doi: 10.1002/nbm.3765. Epub 2017 Jul 14.

38.

Assessing Prostate Cancer Aggressiveness with Hyperpolarized Dual-Agent 3D Dynamic Imaging of Metabolism and Perfusion.

Chen HY, Larson PEZ, Bok RA, von Morze C, Sriram R, Delos Santos R, Delos Santos J, Gordon JW, Bahrami N, Ferrone M, Kurhanewicz J, Vigneron DB.

Cancer Res. 2017 Jun 15;77(12):3207-3216. doi: 10.1158/0008-5472.CAN-16-2083. Epub 2017 Apr 20.

39.

Metabolic Profiling of IDH Mutation and Malignant Progression in Infiltrating Glioma.

Jalbert LE, Elkhaled A, Phillips JJ, Neill E, Williams A, Crane JC, Olson MP, Molinaro AM, Berger MS, Kurhanewicz J, Ronen SM, Chang SM, Nelson SJ.

Sci Rep. 2017 Mar 22;7:44792. doi: 10.1038/srep44792.

40.

Dicarboxylic acids as pH sensors for hyperpolarized 13C magnetic resonance spectroscopic imaging.

Korenchan DE, Taglang C, von Morze C, Blecha JE, Gordon JW, Sriram R, Larson PEZ, Vigneron DB, VanBrocklin HF, Kurhanewicz J, Wilson DM, Flavell RR.

Analyst. 2017 May 2;142(9):1429-1433. doi: 10.1039/c7an00076f.

42.

Development of high resolution 3D hyperpolarized carbon-13 MR molecular imaging techniques.

Milshteyn E, von Morze C, Reed GD, Shang H, Shin PJ, Zhu Z, Chen HY, Bok R, Goga A, Kurhanewicz J, Larson PE, Vigneron DB.

Magn Reson Imaging. 2017 May;38:152-162. doi: 10.1016/j.mri.2017.01.003. Epub 2017 Jan 7.

43.

Monitoring acute metabolic changes in the liver and kidneys induced by fructose and glucose using hyperpolarized [2-13 C]dihydroxyacetone.

Marco-Rius I, von Morze C, Sriram R, Cao P, Chang GY, Milshteyn E, Bok RA, Ohliger MA, Pearce D, Kurhanewicz J, Larson PE, Vigneron DB, Merritt M.

Magn Reson Med. 2017 Jan;77(1):65-73. doi: 10.1002/mrm.26525. Epub 2016 Nov 17.

44.

Spectrally selective three-dimensional dynamic balanced steady-state free precession for hyperpolarized C-13 metabolic imaging with spectrally selective radiofrequency pulses.

Shang H, Sukumar S, von Morze C, Bok RA, Marco-Rius I, Kerr A, Reed GD, Milshteyn E, Ohliger MA, Kurhanewicz J, Larson PEZ, Pauly JM, Vigneron DB.

Magn Reson Med. 2017 Sep;78(3):963-975. doi: 10.1002/mrm.26480. Epub 2016 Oct 21.

45.

Imaging Renal Urea Handling in Rats at Millimeter Resolution using Hyperpolarized Magnetic Resonance Relaxometry.

Reed GD, von Morze C, Verkman AS, Koelsch BL, Chaumeil MM, Lustig M, Ronen SM, Bok RA, Sands JM, Larson PE, Wang ZJ, Larsen JH, Kurhanewicz J, Vigneron DB.

Tomography. 2016 Jun;2(2):125-135.

46.

18F Fluorocholine Dynamic Time-of-Flight PET/MR Imaging in Patients with Newly Diagnosed Intermediate- to High-Risk Prostate Cancer: Initial Clinical-Pathologic Comparisons.

Choi JY, Yang J, Noworolski SM, Behr S, Chang AJ, Simko JP, Nguyen HG, Carroll PR, Kurhanewicz J, Seo Y.

Radiology. 2017 Feb;282(2):429-436. doi: 10.1148/radiol.2016160220. Epub 2016 Aug 11.

47.

Separation of extra- and intracellular metabolites using hyperpolarized (13)C diffusion weighted MR.

Koelsch BL, Sriram R, Keshari KR, Leon Swisher C, Van Criekinge M, Sukumar S, Vigneron DB, Wang ZJ, Larson PEZ, Kurhanewicz J.

J Magn Reson. 2016 Sep;270:115-123. doi: 10.1016/j.jmr.2016.07.002. Epub 2016 Jul 9.

48.

Combining hyperpolarized 13 C MRI with a liver-specific gadolinium contrast agent for selective assessment of hepatocyte metabolism.

Ohliger MA, von Morze C, Marco-Rius I, Gordon J, Larson PEZ, Bok R, Chen HY, Kurhanewicz J, Vigneron D.

Magn Reson Med. 2017 Jun;77(6):2356-2363. doi: 10.1002/mrm.26296. Epub 2016 Jun 14.

49.

Non-invasive differentiation of benign renal tumors from clear cell renal cell carcinomas using clinically translatable hyperpolarized 13C pyruvate magnetic resonance.

Sriram R, Van Criekinge M, DeLos Santos J, Keshari KR, Wilson DM, Peehl D, Kurhanewicz J, Wang ZJ.

Tomography. 2016 Mar;2(1):35-42.

50.

Practical aspects of prostate MRI: hardware and software considerations, protocols, and patient preparation.

Starobinets O, Korn N, Iqbal S, Noworolski SM, Zagoria R, Kurhanewicz J, Westphalen AC.

Abdom Radiol (NY). 2016 May;41(5):817-30. doi: 10.1007/s00261-015-0590-x.

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