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Items: 16

1.

A High-Throughput Immune-Oncology Screen Identifies EGFR Inhibitors as Potent Enhancers of Antigen-Specific Cytotoxic T-lymphocyte Tumor Cell Killing.

Lizotte PH, Hong RL, Luster TA, Cavanaugh ME, Taus LJ, Wang S, Dhaneshwar A, Mayman N, Yang A, Kulkarni M, Badalucco L, Fitzpatrick E, Kao HF, Kuraguchi M, Bittinger M, Kirschmeier PT, Gray NS, Barbie DA, Jänne PA.

Cancer Immunol Res. 2018 Sep 21. doi: 10.1158/2326-6066.CIR-18-0193. [Epub ahead of print]

PMID:
30242021
2.

Adaptive resistance to therapeutic PD-1 blockade is associated with upregulation of alternative immune checkpoints.

Koyama S, Akbay EA, Li YY, Herter-Sprie GS, Buczkowski KA, Richards WG, Gandhi L, Redig AJ, Rodig SJ, Asahina H, Jones RE, Kulkarni MM, Kuraguchi M, Palakurthi S, Fecci PE, Johnson BE, Janne PA, Engelman JA, Gangadharan SP, Costa DB, Freeman GJ, Bueno R, Hodi FS, Dranoff G, Wong KK, Hammerman PS.

Nat Commun. 2016 Feb 17;7:10501. doi: 10.1038/ncomms10501.

3.

Apc inhibition of Wnt signaling regulates supernumerary tooth formation during embryogenesis and throughout adulthood.

Wang XP, O'Connell DJ, Lund JJ, Saadi I, Kuraguchi M, Turbe-Doan A, Cavallesco R, Kim H, Park PJ, Harada H, Kucherlapati R, Maas RL.

Development. 2009 Jun;136(11):1939-49. doi: 10.1242/dev.033803.

4.

Genetic mechanisms in Apc-mediated mammary tumorigenesis.

Kuraguchi M, Ohene-Baah NY, Sonkin D, Bronson RT, Kucherlapati R.

PLoS Genet. 2009 Feb;5(2):e1000367. doi: 10.1371/journal.pgen.1000367. Epub 2009 Feb 6.

5.

Loss of Rb1 in the gastrointestinal tract of Apc1638N mice promotes tumors of the cecum and proximal colon.

Kucherlapati MH, Yang K, Fan K, Kuraguchi M, Sonkin D, Rosulek A, Lipkin M, Bronson RT, Aronow BJ, Kucherlapati R.

Proc Natl Acad Sci U S A. 2008 Oct 7;105(40):15493-8. doi: 10.1073/pnas.0802933105. Epub 2008 Oct 1.

6.

Novel roles for MLH3 deficiency and TLE6-like amplification in DNA mismatch repair-deficient gastrointestinal tumorigenesis and progression.

Chen PC, Kuraguchi M, Velasquez J, Wang Y, Yang K, Edwards R, Gillen D, Edelmann W, Kucherlapati R, Lipkin SM.

PLoS Genet. 2008 Jun 13;4(6):e1000092. doi: 10.1371/journal.pgen.1000092.

7.

Tumor progression in Apc(1638N) mice with Exo1 and Fen1 deficiencies.

Kucherlapati M, Nguyen A, Kuraguchi M, Yang K, Fan K, Bronson R, Wei K, Lipkin M, Edelmann W, Kucherlapati R.

Oncogene. 2007 Sep 20;26(43):6297-306. Epub 2007 Apr 23.

PMID:
17452984
8.

Adenomatous polyposis coli (APC) is required for normal development of skin and thymus.

Kuraguchi M, Wang XP, Bronson RT, Rothenberg R, Ohene-Baah NY, Lund JJ, Kucherlapati M, Maas RL, Kucherlapati R.

PLoS Genet. 2006 Sep 15;2(9):e146. Epub 2006 Jul 28.

9.

Mbd4 inactivation increases Cright-arrowT transition mutations and promotes gastrointestinal tumor formation.

Wong E, Yang K, Kuraguchi M, Werling U, Avdievich E, Fan K, Fazzari M, Jin B, Brown AM, Lipkin M, Edelmann W.

Proc Natl Acad Sci U S A. 2002 Nov 12;99(23):14937-42. Epub 2002 Nov 4.

10.

Haploinsufficiency of Flap endonuclease (Fen1) leads to rapid tumor progression.

Kucherlapati M, Yang K, Kuraguchi M, Zhao J, Lia M, Heyer J, Kane MF, Fan K, Russell R, Brown AM, Kneitz B, Edelmann W, Kolodner RD, Lipkin M, Kucherlapati R.

Proc Natl Acad Sci U S A. 2002 Jul 23;99(15):9924-9. Epub 2002 Jul 15.

11.

The distinct spectra of tumor-associated Apc mutations in mismatch repair-deficient Apc1638N mice define the roles of MSH3 and MSH6 in DNA repair and intestinal tumorigenesis.

Kuraguchi M, Yang K, Wong E, Avdievich E, Fan K, Kolodner RD, Lipkin M, Brown AM, Kucherlapati R, Edelmann W.

Cancer Res. 2001 Nov 1;61(21):7934-42.

12.

Down-regulation of beta-catenin TCF signaling is linked to colonic epithelial cell differentiation.

Mariadason JM, Bordonaro M, Aslam F, Shi L, Kuraguchi M, Velcich A, Augenlicht LH.

Cancer Res. 2001 Apr 15;61(8):3465-71.

13.

Differences in susceptibility to colonic stem cell somatic mutation in three strains of mice.

Kuraguchi M, Cook H, Williams ED, Thomas GA.

J Pathol. 2001 Apr;193(4):517-21.

PMID:
11276012
14.

Tumor-associated Apc mutations in Mlh1-/- Apc1638N mice reveal a mutational signature of Mlh1 deficiency.

Kuraguchi M, Edelmann W, Yang K, Lipkin M, Kucherlapati R, Brown AM.

Oncogene. 2000 Nov 23;19(50):5755-63.

15.

Tumorigenesis in Mlh1 and Mlh1/Apc1638N mutant mice.

Edelmann W, Yang K, Kuraguchi M, Heyer J, Lia M, Kneitz B, Fan K, Brown AM, Lipkin M, Kucherlapati R.

Cancer Res. 1999 Mar 15;59(6):1301-7.

16.

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