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Items: 7


The three-dimensional structure of VIM-31--a metallo-β-lactamase from Enterobacter cloacae in its native and oxidized form.

Kupper MB, Herzog K, Bennink S, Schlömer P, Bogaerts P, Glupczynski Y, Fischer R, Bebrone C, Hoffmann KM.

FEBS J. 2015 Jun;282(12):2352-60. doi: 10.1111/febs.13283. Epub 2015 Apr 13.


GES-18, a new carbapenem-hydrolyzing GES-Type β-lactamase from Pseudomonas aeruginosa that contains Ile80 and Ser170 residues.

Bebrone C, Bogaerts P, Delbrück H, Bennink S, Kupper MB, Rezende de Castro R, Glupczynski Y, Hoffmann KM.

Antimicrob Agents Chemother. 2013 Jan;57(1):396-401. doi: 10.1128/AAC.01784-12. Epub 2012 Oct 31.


Kinetic and crystallographic studies of extended-spectrum GES-11, GES-12, and GES-14 β-lactamases.

Delbrück H, Bogaerts P, Kupper MB, Rezende de Castro R, Bennink S, Glupczynski Y, Galleni M, Hoffmann KM, Bebrone C.

Antimicrob Agents Chemother. 2012 Nov;56(11):5618-25. doi: 10.1128/AAC.01272-12. Epub 2012 Aug 20.


Effects and mechanisms of angiotensin II receptor blockade with telmisartan in a normotensive model of mesangioproliferative nephritis.

Villa L, Boor P, Konieczny A, Kunter U, van Roeyen CR, Denecke B, Gan L, Kupper MB, Hoffmann K, Eitner F, Ostendorf T, Floege J.

Nephrol Dial Transplant. 2011 Oct;26(10):3131-43. doi: 10.1093/ndt/gfr096. Epub 2011 Mar 17.


Broad antibiotic resistance profile of the subclass B3 metallo-β-lactamase GOB-1, a di-zinc enzyme.

Horsfall LE, Izougarhane Y, Lassaux P, Selevsek N, Liénard BM, Poirel L, Kupper MB, Hoffmann KM, Frère JM, Galleni M, Bebrone C.

FEBS J. 2011 Apr;278(8):1252-63. doi: 10.1111/j.1742-4658.2011.08046.x. Epub 2011 Mar 4.


The structure of the dizinc subclass B2 metallo-beta-lactamase CphA reveals that the second inhibitory zinc ion binds in the histidine site.

Bebrone C, Delbrück H, Kupper MB, Schlömer P, Willmann C, Frère JM, Fischer R, Galleni M, Hoffmann KM.

Antimicrob Agents Chemother. 2009 Oct;53(10):4464-71. doi: 10.1128/AAC.00288-09. Epub 2009 Aug 3.


Preliminary X-ray analysis of a human V(H) fragment at 1.8 A resolution.

Gaur RK, Kupper MB, Fischer R, Hoffmann KM.

Acta Crystallogr D Biol Crystallogr. 2004 May;60(Pt 5):965-7. Epub 2004 Apr 21.


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