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Items: 1 to 50 of 175

1.

The cytosolic form of aspartate aminotransferase is required for full activation of TOR complex 1 in fission yeast.

Reidman S, Cohen A, Kupiec M, Weisman R.

J Biol Chem. 2019 Oct 22. pii: jbc.RA119.010101. doi: 10.1074/jbc.RA119.010101. [Epub ahead of print]

2.

Genome architecture and stability in the Saccharomyces cerevisiae knockout collection.

Puddu F, Herzog M, Selivanova A, Wang S, Zhu J, Klein-Lavi S, Gordon M, Meirman R, Millan-Zambrano G, Ayestaran I, Salguero I, Sharan R, Li R, Kupiec M, Jackson SP.

Nature. 2019 Sep;573(7774):416-420. doi: 10.1038/s41586-019-1549-9. Epub 2019 Sep 11.

PMID:
31511699
3.

A role for the yeast PCNA unloader Elg1 in eliciting the DNA damage checkpoint.

Sau S, Kupiec M.

Curr Genet. 2019 Jul 22. doi: 10.1007/s00294-019-01020-7. [Epub ahead of print] Review.

PMID:
31332476
4.

The Yeast PCNA Unloader Elg1 RFC-Like Complex Plays a Role in Eliciting the DNA Damage Checkpoint.

Sau S, Liefshitz B, Kupiec M.

MBio. 2019 Jun 11;10(3). pii: e01159-19. doi: 10.1128/mBio.01159-19.

5.

The electrochemical profiles of Auranofin and Aubipyc, two representative medicinal gold compounds: A comparative study.

Kupiec M, Ziółkowski R, Massai L, Messori L, Pawlak K.

J Inorg Biochem. 2019 Sep;198:110714. doi: 10.1016/j.jinorgbio.2019.110714. Epub 2019 May 28.

PMID:
31170580
6.

Carbon catabolite repression: not only for glucose.

Simpson-Lavy K, Kupiec M.

Curr Genet. 2019 Dec;65(6):1321-1323. doi: 10.1007/s00294-019-00996-6. Epub 2019 May 22. Review.

PMID:
31119370
7.

Carbon Catabolite Repression in Yeast is Not Limited to Glucose.

Simpson-Lavy K, Kupiec M.

Sci Rep. 2019 Apr 24;9(1):6491. doi: 10.1038/s41598-019-43032-w.

8.

Old and New Threats-Trace Metals and Fluoride Contamination in Soils at Defunct Smithy Sites.

Kupiec M, Pieńkowski P, Bosiacka B, Gutowska I, Kupnicka P, Prokopowicz A, Chlubek D, Baranowska-Bosiacka I.

Int J Environ Res Public Health. 2019 Mar 6;16(5). pii: E819. doi: 10.3390/ijerph16050819.

9.

Comparative Analysis of Normalization Methods for Network Propagation.

Biran H, Kupiec M, Sharan R.

Front Genet. 2019 Jan 22;10:4. doi: 10.3389/fgene.2019.00004. eCollection 2019.

10.

The Main Role of Srs2 in DNA Repair Depends on Its Helicase Activity, Rather than on Its Interactions with PCNA or Rad51.

Bronstein A, Gershon L, Grinberg G, Alonso-Perez E, Kupiec M.

MBio. 2018 Jul 17;9(4). pii: e01192-18. doi: 10.1128/mBio.01192-18.

11.

TOR complex 2 in fission yeast is required for chromatin-mediated gene silencing and assembly of heterochromatic domains at subtelomeres.

Cohen A, Habib A, Laor D, Yadav S, Kupiec M, Weisman R.

J Biol Chem. 2018 May 25;293(21):8138-8150. doi: 10.1074/jbc.RA118.002270. Epub 2018 Apr 9.

12.

Tight Regulation of Srs2 Helicase Activity Is Crucial for Proper Functioning of DNA Repair Mechanisms.

Bronstein A, Bramson S, Shemesh K, Liefshitz B, Kupiec M.

G3 (Bethesda). 2018 May 4;8(5):1615-1626. doi: 10.1534/g3.118.200181.

13.

Frequent ploidy changes in growing yeast cultures.

Harari Y, Ram Y, Kupiec M.

Curr Genet. 2018 Oct;64(5):1001-1004. doi: 10.1007/s00294-018-0823-y. Epub 2018 Mar 10. Review.

PMID:
29525927
14.

WebPropagate: A Web Server for Network Propagation.

Biran H, Almozlino T, Kupiec M, Sharan R.

J Mol Biol. 2018 Jul 20;430(15):2231-2236. doi: 10.1016/j.jmb.2018.02.025. Epub 2018 Mar 7.

PMID:
29524510
15.

Spontaneous Changes in Ploidy Are Common in Yeast.

Harari Y, Ram Y, Rappoport N, Hadany L, Kupiec M.

Curr Biol. 2018 Mar 19;28(6):825-835.e4. doi: 10.1016/j.cub.2018.01.062. Epub 2018 Mar 1.

16.

Pivotal roles of PCNA loading and unloading in heterochromatin function.

Janke R, King GA, Kupiec M, Rine J.

Proc Natl Acad Sci U S A. 2018 Feb 27;115(9):E2030-E2039. doi: 10.1073/pnas.1721573115. Epub 2018 Feb 13.

17.

The extent of ribosome queuing in budding yeast.

Diament A, Feldman A, Schochet E, Kupiec M, Arava Y, Tuller T.

PLoS Comput Biol. 2018 Jan 29;14(1):e1005951. doi: 10.1371/journal.pcbi.1005951. eCollection 2018 Jan.

18.

A reversible liquid drop aggregation controls glucose response in yeast.

Simpson-Lavy K, Kupiec M.

Curr Genet. 2018 Aug;64(4):785-788. doi: 10.1007/s00294-018-0805-0. Epub 2018 Jan 10. Review.

PMID:
29322248
19.

The Std1 Activator of the Snf1/AMPK Kinase Controls Glucose Response in Yeast by a Regulated Protein Aggregation.

Simpson-Lavy K, Xu T, Johnston M, Kupiec M.

Mol Cell. 2017 Dec 21;68(6):1120-1133.e3. doi: 10.1016/j.molcel.2017.11.016. Epub 2017 Dec 14.

20.

Rnr1's role in telomere elongation cannot be replaced by Rnr3: a role beyond dNTPs?

Maicher A, Kupiec M.

Curr Genet. 2018 Jun;64(3):547-550. doi: 10.1007/s00294-017-0779-3. Epub 2017 Nov 8. Review.

PMID:
29119271
21.

The evolutionarily conserved factor Sus1/ENY2 plays a role in telomere length maintenance.

Galán A, García-Oliver E, Nuño-Cabanes C, Rubinstein L, Kupiec M, Rodríguez-Navarro S.

Curr Genet. 2018 Jun;64(3):635-644. doi: 10.1007/s00294-017-0778-4. Epub 2017 Nov 7.

PMID:
29116388
22.

Rnr1, but not Rnr3, facilitates the sustained telomerase-dependent elongation of telomeres.

Maicher A, Gazy I, Sharma S, Marjavaara L, Grinberg G, Shemesh K, Chabes A, Kupiec M.

PLoS Genet. 2017 Oct 25;13(10):e1007082. doi: 10.1371/journal.pgen.1007082. eCollection 2017 Oct.

23.

Do long telomeres affect cellular fitness?

Harari Y, Kupiec M.

Curr Genet. 2018 Feb;64(1):173-176. doi: 10.1007/s00294-017-0746-z. Epub 2017 Sep 8. Review.

PMID:
28887594
24.

Long Telomeres Do Not Affect Cellular Fitness in Yeast.

Harari Y, Zadok-Laviel S, Kupiec M.

MBio. 2017 Aug 29;8(4). pii: e01314-17. doi: 10.1128/mBio.01314-17.

25.

Mec1ATR is needed for extensive telomere elongation in response to ethanol in yeast.

Harari Y, Kupiec M.

Curr Genet. 2018 Feb;64(1):223-234. doi: 10.1007/s00294-017-0728-1. Epub 2017 Aug 5.

PMID:
28780613
26.

GLADIATOR: a global approach for elucidating disease modules.

Silberberg Y, Kupiec M, Sharan R.

Genome Med. 2017 May 26;9(1):48. doi: 10.1186/s13073-017-0435-z.

27.

A New Method, "Reverse Yeast Two-Hybrid Array" (RYTHA), Identifies Mutants that Dissociate the Physical Interaction Between Elg1 and Slx5.

Lev I, Shemesh K, Volpe M, Sau S, Levinton N, Molco M, Singh S, Liefshitz B, Ben Aroya S, Kupiec M.

Genetics. 2017 Jul;206(3):1683-1697. doi: 10.1534/genetics.117.200451. Epub 2017 May 5.

28.

A structure-function analysis of the yeast Elg1 protein reveals the importance of PCNA unloading in genome stability maintenance.

Shemesh K, Sebesta M, Pacesa M, Sau S, Bronstein A, Parnas O, Liefshitz B, Venclovas C, Krejci L, Kupiec M.

Nucleic Acids Res. 2017 Apr 7;45(6):3189-3203. doi: 10.1093/nar/gkw1348.

29.

Ubiquitylation-dependent oligomerization regulates activity of Nedd4 ligases.

Attali I, Tobelaim WS, Persaud A, Motamedchaboki K, Simpson-Lavy KJ, Mashahreh B, Levin-Kravets O, Keren-Kaplan T, Pilzer I, Kupiec M, Wiener R, Wolf DA, Rotin D, Prag G.

EMBO J. 2017 Feb 15;36(4):425-440. doi: 10.15252/embj.201694314. Epub 2017 Jan 9.

30.

Role of the ESCRT Complexes in Telomere Biology.

Dieckmann AK, Babin V, Harari Y, Eils R, König R, Luke B, Kupiec M.

MBio. 2016 Nov 8;7(6). pii: e01793-16. doi: 10.1128/mBio.01793-16.

31.

Alternative clamp loaders/unloaders.

Kupiec M.

FEMS Yeast Res. 2016 Nov;16(7). pii: fow084. Epub 2016 Sep 24. Review.

PMID:
27664980
32.

Utilizing yeast chemogenomic profiles for the prediction of pharmacogenomic associations in humans.

Silberberg Y, Kupiec M, Sharan R.

Sci Rep. 2016 Mar 30;6:23703. doi: 10.1038/srep23703.

33.
34.

Mixed Integer Linear Programming based machine learning approach identifies regulators of telomerase in yeast.

Poos AM, Maicher A, Dieckmann AK, Oswald M, Eils R, Kupiec M, Luke B, König R.

Nucleic Acids Res. 2016 Jun 2;44(10):e93. doi: 10.1093/nar/gkw111. Epub 2016 Feb 22.

35.

Systematic identification and correction of annotation errors in the genetic interaction map of Saccharomyces cerevisiae.

Atias N, Kupiec M, Sharan R.

Nucleic Acids Res. 2016 Mar 18;44(5):e50. doi: 10.1093/nar/gkv1284. Epub 2015 Nov 23.

36.

Cross-Talk between Carbon Metabolism and the DNA Damage Response in S. cerevisiae.

Simpson-Lavy KJ, Bronstein A, Kupiec M, Johnston M.

Cell Rep. 2015 Sep 22;12(11):1865-75. doi: 10.1016/j.celrep.2015.08.025. Epub 2015 Sep 3.

37.

Regulation of Elg1 activity by phosphorylation.

Shkedy D, Singh N, Shemesh K, Amir A, Geiger T, Liefshitz B, Harari Y, Kupiec M.

Cell Cycle. 2015;14(23):3689-97. doi: 10.1080/15384101.2015.1068475.

38.

TORC1 Regulates Developmental Responses to Nitrogen Stress via Regulation of the GATA Transcription Factor Gaf1.

Laor D, Cohen A, Kupiec M, Weisman R.

MBio. 2015 Jul 7;6(4):e00959. doi: 10.1128/mBio.00959-15.

39.

Fungal stress biology: a preface to the Fungal Stress Responses special edition.

Rangel DE, Alder-Rangel A, Dadachova E, Finlay RD, Kupiec M, Dijksterhuis J, Braga GU, Corrochano LM, Hallsworth JE.

Curr Genet. 2015 Aug;61(3):231-8. doi: 10.1007/s00294-015-0500-3. Epub 2015 Jun 27.

PMID:
26116075
40.

Use of high-performance liquid chromatography-tandem electrospray ionization mass spectrometry to assess the speciation of a ruthenium(III) anticancer drug in the cytosol of cancer cells.

Matczuk M, Kupiec M, Legat J, Pawlak K, Timerbaev AR, Jarosz M.

Anal Bioanal Chem. 2015 Jun;407(16):4857-62. doi: 10.1007/s00216-015-8684-4. Epub 2015 Apr 21.

PMID:
25895946
41.

A shotgun metalloproteomic approach enables identification of proteins involved in the speciation of a ruthenium anticancer drug in the cytosol of cancer cells.

Matczuk M, Kupiec M, Legat J, Pawlak K, Timerbaev AR, Jarosz M.

Analyst. 2015 May 21;140(10):3492-9. doi: 10.1039/c5an00426h. Epub 2015 Apr 1.

PMID:
25827723
42.

Elg1, a central player in genome stability.

Gazy I, Liefshitz B, Parnas O, Kupiec M.

Mutat Res Rev Mutat Res. 2015 Jan-Mar;763:267-79. doi: 10.1016/j.mrrev.2014.11.007. Epub 2014 Nov 24. Review.

PMID:
25795125
43.

Editorial from the new Editor-in-Chief.

Kupiec M.

Curr Genet. 2015 Feb;61(1):1-2. doi: 10.1007/s00294-014-0464-8. No abstract available.

PMID:
25503490
44.

The effects of telomere shortening on cancer cells: a network model of proteomic and microRNA analysis.

Uziel O, Yosef N, Sharan R, Ruppin E, Kupiec M, Kushnir M, Beery E, Cohen-Diker T, Nordenberg J, Lahav M.

Genomics. 2015 Jan;105(1):5-16. doi: 10.1016/j.ygeno.2014.10.013. Epub 2014 Nov 13.

45.

Glycan degradation (GlyDeR) analysis predicts mammalian gut microbiota abundance and host diet-specific adaptations.

Eilam O, Zarecki R, Oberhardt M, Ursell LK, Kupiec M, Knight R, Gophna U, Ruppin E.

MBio. 2014 Aug 12;5(4). pii: e01526-14. doi: 10.1128/mBio.01526-14.

47.

Biology of telomeres: lessons from budding yeast.

Kupiec M.

FEMS Microbiol Rev. 2014 Mar;38(2):144-71. Review.

48.

Telomere length kinetics assay (TELKA) sorts the telomere length maintenance (tlm) mutants into functional groups.

Rubinstein L, Ungar L, Harari Y, Babin V, Ben-Aroya S, Merenyi G, Marjavaara L, Chabes A, Kupiec M.

Nucleic Acids Res. 2014 Jun;42(10):6314-25. doi: 10.1093/nar/gku267. Epub 2014 Apr 11.

49.

A high-throughput chemical screen with FDA approved drugs reveals that the antihypertensive drug Spironolactone impairs cancer cell survival by inhibiting homology directed repair.

Shahar OD, Kalousi A, Eini L, Fisher B, Weiss A, Darr J, Mazina O, Bramson S, Kupiec M, Eden A, Meshorer E, Mazin AV, Brino L, Goldberg M, Soutoglou E.

Nucleic Acids Res. 2014 May;42(9):5689-701. doi: 10.1093/nar/gku217. Epub 2014 Mar 25.

50.

A method for predicting protein-protein interaction types.

Silberberg Y, Kupiec M, Sharan R.

PLoS One. 2014 Mar 13;9(3):e90904. doi: 10.1371/journal.pone.0090904. eCollection 2014.

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