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Computerized Adaptive Tests for Rapid and Accurate Assessment of Psychopathology Dimensions in Youth.

Gibbons RD, Kupfer DJ, Frank E, Lahey BB, George-Milford BA, Biernesser CL, Porta G, Moore TL, Kim JB, Brent DA.

J Am Acad Child Adolesc Psychiatry. 2019 Aug 26. pii: S0890-8567(19)31466-2. doi: 10.1016/j.jaac.2019.08.009. [Epub ahead of print]


Exploring gene expression biomarker candidates for neurobehavioral impairment from total sleep deprivation.

Uyhelji HA, Kupfer DM, White VL, Jackson ML, Van Dongen HPA, Burian DM.

BMC Genomics. 2018 May 9;19(1):341. doi: 10.1186/s12864-018-4664-3.


Exercise attenuates negative effects of abstinence during 72 hours of smoking deprivation.

Conklin CA, Soreca I, Kupfer DJ, Cheng Y, Salkeld RP, Mumma JM, Jakicic JM, Joyce CJ.

Exp Clin Psychopharmacol. 2017 Aug;25(4):265-272. doi: 10.1037/pha0000128. Epub 2017 Jul 6.


Assessment of a Person-Level Risk Calculator to Predict New-Onset Bipolar Spectrum Disorder in Youth at Familial Risk.

Hafeman DM, Merranko J, Goldstein TR, Axelson D, Goldstein BI, Monk K, Hickey MB, Sakolsky D, Diler R, Iyengar S, Brent DA, Kupfer DJ, Kattan MW, Birmaher B.

JAMA Psychiatry. 2017 Aug 1;74(8):841-847. doi: 10.1001/jamapsychiatry.2017.1763.


Development of a Computerized Adaptive Test Suicide Scale-The CAT-SS.

Gibbons RD, Kupfer D, Frank E, Moore T, Beiser DG, Boudreaux ED.

J Clin Psychiatry. 2017 Nov/Dec;78(9):1376-1382. doi: 10.4088/JCP.16m10922.


Objective Sleep Duration Is Prospectively Associated With Endothelial Health.

Hall MH, Mulukutla S, Kline CE, Samuelsson LB, Taylor BJ, Thayer JF, Krafty RT, Frank E, Kupfer DJ.

Sleep. 2017 Jan 1;40(1). doi: 10.1093/sleep/zsw003.


Longitudinal sleep phenotypes among offspring of bipolar parents and community controls.

Levenson JC, Soehner A, Rooks B, Goldstein TR, Diler R, Merranko J, Axelson D, Goldstein BI, Brent DA, Hafeman D, Hickey MB, Monk K, Sakolsky D, Kupfer DJ, Birmaher B.

J Affect Disord. 2017 Jun;215:30-36. doi: 10.1016/j.jad.2017.03.011. Epub 2017 Mar 6.


The Relationship Between Stressful Life Events and Axis I Diagnoses Among Adolescent Offspring of Probands With Bipolar and Non-Bipolar Psychiatric Disorders and Healthy Controls: The Pittsburgh Bipolar Offspring Study (BIOS).

Pan LA, Goldstein TR, Rooks BT, Hickey M, Fan JY, Merranko J, Monk K, Diler RS, Sakolsky DJ, Hafeman D, Iyengar S, Goldstein B, Kupfer DJ, Axelson DA, Brent DA, Birmaher B.

J Clin Psychiatry. 2017 Mar;78(3):e234-e243. doi: 10.4088/JCP.15m09815.


Progress on the Neuroscience-Based Nomenclature (NbN) for Psychotropic Medications.

Blier P, Oquendo MA, Kupfer DJ.

Neuropsychopharmacology. 2017 Sep;42(10):1927-1928. doi: 10.1038/npp.2017.33. Epub 2017 Feb 9. No abstract available.


Einstein, measurement, and prediction.

Gibbons RD, Beiser DG, Boudreaux ED, Kupfer DJ.

J Affect Disord. 2019 Sep 1;256:674-675. doi: 10.1016/j.jad.2016.12.016. Epub 2016 Dec 21. No abstract available.


Immuno-psychiatry: an agenda for clinical practice and innovative research.

Leboyer M, Berk M, Yolken RH, Tamouza R, Kupfer D, Groc L.

BMC Med. 2016 Oct 28;14(1):173.


Association analysis of successive events data in the presence of competing risks.

Chen X, Cheng Y, Frank E, Kupfer DJ.

Stat Methods Med Res. 2018 Jun;27(6):1661-1682. doi: 10.1177/0962280216667645. Epub 2016 Sep 19.


Sleep-Wake Differences in Relative Regional Cerebral Metabolic Rate for Glucose among Patients with Insomnia Compared with Good Sleepers.

Kay DB, Karim HT, Soehner AM, Hasler BP, Wilckens KA, James JA, Aizenstein HJ, Price JC, Rosario BL, Kupfer DJ, Germain A, Hall MH, Franzen PL, Nofzinger EA, Buysse DJ.

Sleep. 2016 Oct 1;39(10):1779-1794.


An approach to revealing clinically relevant subgroups across the mood spectrum.

Wallace ML, Simsek B, Kupfer DJ, Swartz HA, Fagiolini A, Frank E.

J Affect Disord. 2016 Oct;203:265-274. doi: 10.1016/j.jad.2016.06.019. Epub 2016 Jun 7.


The association between meal timing and frequency with cardiometabolic profile in patients with bipolar disorder.

Soreca I, Wallace ML, Hall MH, Hasler BP, Frank E, Kupfer DJ.

Acta Psychiatr Scand. 2016 Jun;133(6):453-8. doi: 10.1111/acps.12578. Epub 2016 Apr 15.


Toward the Definition of a Bipolar Prodrome: Dimensional Predictors of Bipolar Spectrum Disorders in At-Risk Youths.

Hafeman DM, Merranko J, Axelson D, Goldstein BI, Goldstein T, Monk K, Hickey MB, Sakolsky D, Diler R, Iyengar S, Brent D, Kupfer D, Birmaher B.

Am J Psychiatry. 2016 Jul 1;173(7):695-704. doi: 10.1176/appi.ajp.2015.15040414. Epub 2016 Feb 19.


The role of non-rapid eye movement slow-wave activity in prefrontal metabolism across young and middle-aged adults.

Wilckens KA, Aizenstein HJ, Nofzinger EA, James JA, Hasler BP, Rosario-Rivera BL, Franzen PL, Germain A, Hall MH, Kupfer DJ, Price JC, Siegle GJ, Buysse DJ.

J Sleep Res. 2016 Jun;25(3):296-306. doi: 10.1111/jsr.12365. Epub 2016 Feb 7.


Computerized Adaptive Diagnosis and Testing of Mental Health Disorders.

Gibbons RD, Weiss DJ, Frank E, Kupfer D.

Annu Rev Clin Psychol. 2016;12:83-104. doi: 10.1146/annurev-clinpsy-021815-093634. Epub 2015 Nov 20. Review.


Social rhythm disrupting events increase the risk of recurrence among individuals with bipolar disorder.

Levenson JC, Wallace ML, Anderson BP, Kupfer DJ, Frank E.

Bipolar Disord. 2015 Dec;17(8):869-79. doi: 10.1111/bdi.12351. Epub 2015 Nov 28.


Differences in sleep disturbances among offspring of parents with and without bipolar disorder: association with conversion to bipolar disorder.

Levenson JC, Axelson DA, Merranko J, Angulo M, Goldstein TR, Mullin BC, Goldstein BI, Brent DA, Diler R, Hickey MB, Monk K, Sakolsky D, Kupfer DJ, Birmaher B.

Bipolar Disord. 2015 Dec;17(8):836-48. doi: 10.1111/bdi.12345. Epub 2015 Nov 7.


A review of the current nomenclature for psychotropic agents and an introduction to the Neuroscience-based Nomenclature.

Zohar J, Stahl S, Moller HJ, Blier P, Kupfer D, Yamawaki S, Uchida H, Spedding M, Goodwin GM, Nutt D.

Eur Neuropsychopharmacol. 2015 Dec;25(12):2318-25. doi: 10.1016/j.euroneuro.2015.08.019. Epub 2015 Sep 7. Review.


Anxiety and DSM-5.

Kupfer DJ.

Dialogues Clin Neurosci. 2015 Sep;17(3):245-6.


Staging bipolar disorder: what data and what models are needed?

Kupfer DJ, Frank E, Ritchey FC.

Lancet Psychiatry. 2015 Jun;2(6):564-70. doi: 10.1016/S2215-0366(15)00096-6. Epub 2015 May 27.


Career Development Institute with Enhanced Mentoring: A Revisit.

Kupfer DJ, Schatzberg AF, Dunn LO, Schneider AK, Moore TL, DeRosier M.

Acad Psychiatry. 2016 Jun;40(3):424-8. doi: 10.1007/s40596-015-0362-5. Epub 2015 Jun 6.


Validation of Computerized Adaptive Testing in an Outpatient Nonacademic Setting: The VOCATIONS Trial.

Achtyes ED, Halstead S, Smart L, Moore T, Frank E, Kupfer DJ, Gibbons R.

Psychiatr Serv. 2015 Oct;66(10):1091-6. doi: 10.1176/ Epub 2015 Jun 1.


Effect of 2 psychotherapies on depression and disease activity in pediatric Crohn's disease.

Szigethy E, Youk AO, Gonzalez-Heydrich J, Bujoreanu SI, Weisz J, Fairclough D, Ducharme P, Jones N, Lotrich F, Keljo D, Srinath A, Bousvaros A, Kupfer D, DeMaso DR.

Inflamm Bowel Dis. 2015 Jun;21(6):1321-8. doi: 10.1097/MIB.0000000000000358.


C-reactive protein alterations in bipolar disorder: a meta-analysis.

Dargél AA, Godin O, Kapczinski F, Kupfer DJ, Leboyer M.

J Clin Psychiatry. 2015 Feb;76(2):142-50. doi: 10.4088/JCP.14r09007.


Diagnostic Precursors to Bipolar Disorder in Offspring of Parents With Bipolar Disorder: A Longitudinal Study.

Axelson D, Goldstein B, Goldstein T, Monk K, Yu H, Hickey MB, Sakolsky D, Diler R, Hafeman D, Merranko J, Iyengar S, Brent D, Kupfer D, Birmaher B.

Am J Psychiatry. 2015 Jul;172(7):638-46. doi: 10.1176/appi.ajp.2014.14010035. Epub 2015 Mar 3.


The longitudinal course of sleep timing and circadian preferences in adults with bipolar disorder.

Seleem MA, Merranko JA, Goldstein TR, Goldstein BI, Axelson DA, Brent DA, Nimgaonkar VL, Diler RS, Sakolsky DJ, Kupfer DJ, Birmaher B.

Bipolar Disord. 2015 Jun;17(4):392-402. doi: 10.1111/bdi.12286. Epub 2014 Dec 19.


An Integrated Risk Reduction Intervention can reduce body mass index in individuals being treated for bipolar I disorder: results from a randomized trial.

Frank E, Wallace ML, Hall M, Hasler B, Levenson JC, Janney CA, Soreca I, Fleming MC, Buttenfield J, Ritchey FC, Kupfer DJ.

Bipolar Disord. 2015 Jun;17(4):424-37. doi: 10.1111/bdi.12283. Epub 2014 Dec 12.


Sleep spindle deficits in antipsychotic-naïve early course schizophrenia and in non-psychotic first-degree relatives.

Manoach DS, Demanuele C, Wamsley EJ, Vangel M, Montrose DM, Miewald J, Kupfer D, Buysse D, Stickgold R, Keshavan MS.

Front Hum Neurosci. 2014 Oct 7;8:762. doi: 10.3389/fnhum.2014.00762. eCollection 2014.


The effects of parental mood on reports of their children's psychopathology.

Maoz H, Goldstein T, Goldstein BI, Axelson DA, Fan J, Hickey MB, Monk K, Sakolsky D, Diler RS, Brent D, Kupfer DJ, Birmaher B.

J Am Acad Child Adolesc Psychiatry. 2014 Oct;53(10):1111-22.e5. doi: 10.1016/j.jaac.2014.07.005. Epub 2014 Aug 6.


Screening for obstructive sleep apnea in patients with bipolar I disorder: comparison between subjective and objective measures.

Soreca I, Buttenfield JA, Hall MH, Kupfer DJ.

Bipolar Disord. 2015 May;17(3):345-8. doi: 10.1111/bdi.12253. Epub 2014 Sep 4.


All the world's a (clinical) stage: rethinking bipolar disorder from a longitudinal perspective.

Frank E, Nimgaonkar VL, Phillips ML, Kupfer DJ.

Mol Psychiatry. 2015 Feb;20(1):23-31. doi: 10.1038/mp.2014.71. Epub 2014 Jul 22. Review.


Randomized efficacy trial of two psychotherapies for depression in youth with inflammatory bowel disease.

Szigethy E, Bujoreanu SI, Youk AO, Weisz J, Benhayon D, Fairclough D, Ducharme P, Gonzalez-Heydrich J, Keljo D, Srinath A, Bousvaros A, Kirshner M, Newara M, Kupfer D, DeMaso DR.

J Am Acad Child Adolesc Psychiatry. 2014 Jul;53(7):726-35. doi: 10.1016/j.jaac.2014.04.014. Epub 2014 May 10.


A proposal for an updated neuropsychopharmacological nomenclature.

Zohar J, Nutt DJ, Kupfer DJ, Moller HJ, Yamawaki S, Spedding M, Stahl SM.

Eur Neuropsychopharmacol. 2014 Jul;24(7):1005-14. doi: 10.1016/j.euroneuro.2013.08.004. Epub 2013 Sep 18.


Cardiovascular risk in bipolar disorder: beyond medication effects and lifestyle factors.

Soreca I, Kupfer DJ.

Braz J Psychiatry. 2014 Jan-Mar;36(1):100. doi: 10.1590/1516-4446-2013-3506. Epub 2014 Mar 1. No abstract available.


Authors' response.

Benhayon D, Youk A, McCarthy FN, Davis S, Keljo DJ, Bousvaros A, Fairclough D, Kupfer D, Buysse DJ, Szigethy EM.

J Pediatr Gastroenterol Nutr. 2014 May;58(5):e51. doi: 10.1097/MPG.0000000000000330. No abstract available.


Neuroscience - informed nosology in psychiatry: are we there yet?

Kupfer DJ.

Asian J Psychiatr. 2014 Feb;7(1):2-3. doi: 10.1016/j.ajp.2013.12.008. Epub 2013 Dec 26. No abstract available.


Dr Gibbons and colleagues reply.

Gibbons RD, Hooker G, Finkelman MD, Weiss DJ, Pilkonis PA, Frank E, Moore T, Kupfer DJ.

J Clin Psychiatry. 2014 Jan;75(1):85-6. doi: 10.4088/JCP.13lr08758a. No abstract available.


DSM-5: new opportunities and challenges for teaching and training.

Kupfer D.

Acad Psychiatry. 2014 Feb;38(1):58-60. doi: 10.1007/s40596-013-0002-x. Epub 2014 Feb 1.


Using peer review to improve research and promote collaboration.

Kupfer DJ, Murphree AN, Pilkonis PA, Cameron JL, Giang RT, Dodds NE, Godard KA, Lewis DA.

Acad Psychiatry. 2014 Feb;38(1):5-10. doi: 10.1007/s40596-013-0027-1. Epub 2014 Jan 22.


Prospective longitudinal course of aggression among adults with bipolar disorder.

Ballester J, Goldstein B, Goldstein TR, Yu H, Axelson D, Monk K, Hickey MB, Diler RS, Sakolsky DJ, Sparks G, Iyengar S, Kupfer DJ, Brent DA, Birmaher B.

Bipolar Disord. 2014 May;16(3):262-9. doi: 10.1111/bdi.12168. Epub 2013 Dec 23.


Dimensional psychopathology in preschool offspring of parents with bipolar disorder.

Maoz H, Goldstein T, Axelson DA, Goldstein BI, Fan J, Hickey MB, Monk K, Sakolsky D, Diler RS, Brent D, Iyengar S, Kupfer DJ, Birmaher B.

J Child Psychol Psychiatry. 2014;55(2):144-53. doi: 10.1111/jcpp.12137. Epub 2013 Dec 30.


Two views on the new DSM-5: DSM-5: a diagnostic guide relevant to both primary care and psychiatric practice.

Kupfer DJ, Kuhl EA, Regier DA.

Am Fam Physician. 2013 Oct 15;88(8):Online. No abstract available.


Depression subtypes in pediatric inflammatory bowel disease.

Szigethy EM, Youk AO, Benhayon D, Fairclough DL, Newara MC, Kirshner MA, Bujoreanu SI, Mrakotsky C, Bousvaros A, Srinath AI, Keljo DJ, Kupfer DJ, DeMaso DR.

J Pediatr Gastroenterol Nutr. 2014 May;58(5):574-81. doi: 10.1097/MPG.0000000000000262.


The prevalence and severity of depressive symptoms along the spectrum of unipolar depressive disorders: a post hoc analysis.

Rakofsky JJ, Schettler PJ, Kinkead BL, Frank E, Judd LL, Kupfer DJ, Rush AJ, Thase ME, Yonkers KA, Rapaport MH.

J Clin Psychiatry. 2013 Nov;74(11):1084-91. doi: 10.4088/JCP.12m08194.


Proceedings of the 2013 MidSouth Computational Biology and Bioinformatics Society (MCBIOS) Conference.

Wren JD, Dozmorov MG, Burian D, Kaundal R, Perkins A, Perkins E, Kupfer DM, Springer GK.

BMC Bioinformatics. 2013;14 Suppl 14:S1. doi: 10.1186/1471-2105-14-S14-S1. Epub 2013 Oct 9.


Failure to report financial disclosure information.

Gibbons RD, Weiss DJ, Pilkonis PA, Frank E, Kupfer DJ.

JAMA Psychiatry. 2014 Jan;71(1):95. doi: 10.1001/jamapsychiatry.2013.3888. No abstract available.


The DSM-5 - an interview with David Kupfer.

Kupfer D.

BMC Med. 2013 Sep 12;11:203.

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