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Loss of function of DOCK4 in myelodysplastic syndromes stem cells is restored by inhibitors of DOCK4 signaling networks.

Sundaravel S, Kuo WL, Jeong JJ, Choudhary GS, Gordon-Mitchell S, Liu H, Bhagat TD, McGraw KL, Gurbuxani S, List AF, Verma A, Wickrema A.

Clin Cancer Res. 2019 Jul 15. pii: clincanres.0924.2019. doi: 10.1158/1078-0432.CCR-19-0924. [Epub ahead of print]


Influence of BOF and GGBFS Based Alkali Activated Materials on the Properties of Porous Concrete.

Kuo WT, Gao YS, Juang CU.

Materials (Basel). 2019 Jul 10;12(14). pii: E2214. doi: 10.3390/ma12142214.

Free Article

Adherence to Home-Based Rehabilitation in Older Adults with Diabetes after Hip Fracture.

Kuo WY, Shyu YL, Wang JS, Chen MC, Wu CC, Chen ML.

Nurs Res. 2019 Jul 5. doi: 10.1097/NNR.0000000000000371. [Epub ahead of print]


Inhibition of protein phosphatase 1 stimulates noncanonical ER stress eIF2α activation to enhance fisetin-induced chemosensitivity in HDAC inhibitor-resistant hepatocellular carcinoma cells.

Liu YS; Yu-Chun; Chang, Kuo WW, Chen MC, Hsu HH, Tu CC, Yeh YL, Viswanadha VP, Liao PH, Huang CY.

Cancers (Basel). 2019 Jun 29;11(7). pii: E918. doi: 10.3390/cancers11070918.


Bioactive Peptide VHVV Upregulates the Long-Term Memory-Related Biomarkers in Adult Spontaneously Hypertensive Rats.

Ju DT, K AK, Kuo WW, Ho TJ, Chang RL, Lin WT, Day CH, Viswanadha VVP, Liao PH, Huang CY.

Int J Mol Sci. 2019 Jun 23;20(12). pii: E3069. doi: 10.3390/ijms20123069.


Amelioration of Experimentally Induced Arthritis by Reducing Reactive Oxygen Species Production through the Intra-Articular Injection of Water-Soluble Fullerenol.

Kuo WS, Weng CT, Chen JH, Wu CL, Shiau AL, Hsieh JL, So EC, Wu PT, Chen SY.

Nanomaterials (Basel). 2019 Jun 23;9(6). pii: E909. doi: 10.3390/nano9060909.


Role of PGRMC1 in cell physiology of cervical cancer.

Shih CC, Chou HC, Chen YJ, Kuo WH, Chan CH, Lin YC, Liao EC, Chang SJ, Chan HL.

Life Sci. 2019 Jun 16. pii: S0024-3205(19)30461-8. doi: 10.1016/j.lfs.2019.06.016. [Epub ahead of print]


Synergistic cardiac pathological hypertrophy induced by high-salt diet in IGF-IIRα cardiac-specific transgenic rats.

Chang RL, Nithiyanantham S, Huang CY, Pai PY, Chang TT, Hu LC, Chen RJ, VijayaPadma V, Kuo WW, Huang CY.

PLoS One. 2019 Jun 18;14(6):e0216285. doi: 10.1371/journal.pone.0216285. eCollection 2019.


Author Correction: A Survival Metadata Analysis Responsive Tool (SMART) for web-based analysis of patient survival and risk.

Chu YC, Kuo WT, Cheng YR, Lee CY, Shiau CY, Tarng DC, Lai F.

Sci Rep. 2019 Jun 4;9(1):8356. doi: 10.1038/s41598-019-43446-6.


The cancer control status and APACHE II score are prognostic factors for critically ill patients with cancer and sepsis.

Kuo WK, Hua CC, Yu CC, Liu YC, Huang CY.

J Formos Med Assoc. 2019 May 30. pii: S0929-6646(18)30596-5. doi: 10.1016/j.jfma.2019.05.012. [Epub ahead of print]


High-density lipoprotein ameliorates palmitic acid-induced lipotoxicity and oxidative dysfunction in H9c2 cardiomyoblast cells via ROS suppression.

Wu KM, Hsu YM, Ying MC, Tsai FJ, Tsai CH, Chung JG, Yang JS, Tang CH, Cheng LY, Su PH, Viswanadha VP, Kuo WW, Huang CY.

Nutr Metab (Lond). 2019 May 28;16:36. doi: 10.1186/s12986-019-0356-5. eCollection 2019.


Circulating microRNAs and vascular calcification in hemodialysis patients.

Lee CT, Lee YT, Tain YL, Ng HY, Kuo WH.

J Int Med Res. 2019 May 30:300060519848949. doi: 10.1177/0300060519848949. [Epub ahead of print]


Bonding Behavior of Repair Material using Fly-Ash/Ground Granulated Blast Furnace Slag-Based Geopolymer.

Kuo WT, Liu MY, Juang CU.

Materials (Basel). 2019 May 24;12(10). pii: E1697. doi: 10.3390/ma12101697.


IGF-IIRα is a novel stress-inducible contributor to cardiac damage underpinning doxorubicin-induced oxidative stress and perturbed mitochondrial autophagy.

Pandey S, Kuo WW, Shen CY, Yeh YL, Ho TJ, Chen RJ, Chang RL, Pai PY, Viswanadha VP, Huang CY, Huang CY.

Am J Physiol Cell Physiol. 2019 May 22. doi: 10.1152/ajpcell.00079.2019. [Epub ahead of print]


Oral administration of green tea Epigallocatechin-3-gallate reduces oxidative stress and enhances restoration of cardiac function in diabetic rats receiving autologous transplantation of adipose-derived stem cells.

Chen TS, Liou SY, Lin HH, Hung MY, Lin CC, Lin YM, Lin KH, Padma VV, Yao CH, Kuo WW, Huang CY.

Arch Physiol Biochem. 2019 May 21:1-8. doi: 10.1080/13813455.2019.1614631. [Epub ahead of print]


Upregulation of IGF-IIRα intensifies doxorubicin-induced cardiac damage.

Pandey S, Kuo WW, Ho TJ, Yeh YL, Shen CY, Chen RJ, Chang RL, Pai PY, Padma VV, Huang CY, Huang CY.

J Cell Biochem. 2019 May 19. doi: 10.1002/jcb.28957. [Epub ahead of print]


Hemopericardium and Cardiac Tamponade as a Complication of Vena Caval Filters: Systematic Review of the Published Literature and the MAUDE Database.

Bikdeli B, Kirtane AJ, Jimenez D, Green P, Spencer FA, Kuo WT, Krumholz HM, Parikh SA.

Clin Appl Thromb Hemost. 2019 Jan-Dec;25:1076029619849111. doi: 10.1177/1076029619849111. No abstract available.


Basics and applications of tumor-derived extracellular vesicles.

Tai YL, Chu PY, Lee BH, Chen KC, Yang CY, Kuo WH, Shen TL.

J Biomed Sci. 2019 May 11;26(1):35. doi: 10.1186/s12929-019-0533-x. Review.


Supercontinuum source-based multi-contrast optical coherence tomography for rat retina imaging.

Syu JP, Buddhakosai W, Chen SJ, Ke CC, Chiou SH, Kuo WC.

Biomed Opt Express. 2018 Nov 12;9(12):6132-6144. doi: 10.1364/BOE.9.006132. eCollection 2018 Dec 1.


Impact of age on pathological complete response and locoregional recurrence in locally advanced breast cancer after neoadjuvant chemotherapy.

Chou HH, Kuo WL, Yu CC, Tsai HP, Shen SC, Chu CH, Yu MC, Lo YF, Dabora MA, Chang HK, Lin YC, Ueng SH, Chen SC.

Biomed J. 2019 Feb;42(1):66-74. doi: 10.1016/ Epub 2019 Mar 28.


ERK1/2 mediates the lipopolysaccharide-induced upregulation of FGF-2, uPA, MMP-2, MMP-9 and cellular migration in cardiac fibroblasts.

Chen LC, Shibu MA, Liu CJ, Han CK, Ju DT, Chen PY, Viswanadha VP, Lai CH, Kuo WW, Huang CY.

Chem Biol Interact. 2019 Jun 1;306:62-69. doi: 10.1016/j.cbi.2019.04.010. Epub 2019 Apr 11.


CHIP attenuates lipopolysaccharide-induced cardiac hypertrophy and apoptosis by promoting NFATc3 proteasomal degradation.

Chao CN, Lai CH, Badrealam KF, Lo JF, Shen CY, Chen CH, Chen RJ, Viswanadha VP, Kuo WW, Huang CY.

J Cell Physiol. 2019 Apr 13. doi: 10.1002/jcp.28614. [Epub ahead of print]


Luteolin: A Natural Flavonoid Enhances the Survival of HUVECs against Oxidative Stress by Modulating AMPK/PKC Pathway.

Ou HC, Pandey S, Hung MY, Huang SH, Hsu PT, Day CH, Pai P, Viswanadha VP, Kuo WW, Huang CY.

Am J Chin Med. 2019;47(3):541-557. doi: 10.1142/S0192415X19500289. Epub 2019 Apr 9.


Cytokine-Regulated Phosphorylation and Activation of TET2 by JAK2 in Hematopoiesis.

Jeong JJ, Gu X, Nie J, Sundaravel S, Liu H, Kuo WL, Bhagat TD, Pradhan K, Cao J, Nischal S, McGraw KL, Bhattacharyya S, Bishop MR, Artz A, Thirman MJ, Moliterno A, Ji P, Levine RL, Godley LA, Steidl U, Bieker JJ, List AF, Saunthararajah Y, He C, Verma A, Wickrema A.

Cancer Discov. 2019 Jun;9(6):778-795. doi: 10.1158/2159-8290.CD-18-1138. Epub 2019 Apr 3.


Investigation of Electrical Stability and Sensitivity of Electric Double Layer Gated Field-Effect Transistors (FETs) for miRNA Detection.

Kuo WC, Sarangadharan I, Pulikkathodi AK, Chen PH, Wang SL, Wu CR, Wang YL.

Sensors (Basel). 2019 Mar 27;19(7). pii: E1484. doi: 10.3390/s19071484.


O-GlcNAcylation disrupts STRA6-retinol signals in kidneys of diabetes.

Chen CH, Lin KD, Ke LY, Liang CJ, Kuo WC, Lee MY, Lee YL, Hsiao PJ, Hsu CC, Shin SJ.

Biochim Biophys Acta Gen Subj. 2019 Jun;1863(6):1059-1069. doi: 10.1016/j.bbagen.2019.03.014. Epub 2019 Mar 21.


Implementation and phase detection of dielectric-grating-coupled surface plasmon resonance sensor for backside incident light.

Kuo WK, Tongpakpanang J, Kuo PH, Kuo SF.

Opt Express. 2019 Feb 18;27(4):3867-3872. doi: 10.1364/OE.27.003867.


Impact of Overdiagnosis on Long-Term Breast Cancer Survival.

Fann JC, Chang KJ, Hsu CY, Yen AM, Yu CP, Chen SL, Kuo WH, Tabár L, Chen HH.

Cancers (Basel). 2019 Mar 7;11(3). pii: E325. doi: 10.3390/cancers11030325.


Catheter-directed aspiration thrombectomy and low-dose thrombolysis for patients with acute unstable pulmonary embolism: Prospective outcomes from a PE registry.

De Gregorio MA, Guirola JA, Kuo WT, Serrano C, Urbano J, Figueredo AL, Sierre S, Quezada CA, Barbero E, Jiménez D.

Int J Cardiol. 2019 Jul 15;287:106-110. doi: 10.1016/j.ijcard.2019.02.061. Epub 2019 Feb 28.


Continuous positive airway pressure improves nocturnal polyuria in ischemic stroke patients with obstructive sleep apnea.

Yu CC, Huang CY, Kuo WK, Chen CY.

Clin Interv Aging. 2019 Jan 31;14:241-247. doi: 10.2147/CIA.S193448. eCollection 2019.


Elucidation of microstructural changes in leaves during senescence using spectral domain optical coherence tomography.

Anna T, Chakraborty S, Cheng CY, Srivastava V, Chiou A, Kuo WC.

Sci Rep. 2019 Feb 4;9(1):1167. doi: 10.1038/s41598-018-38165-3.


Endodontic Infection-induced Inflammation Resembling Osteomyelitis of the Jaws in Toll-like Receptor 2/Interleukin 10 Double-knockout Mice.

Sasaki H, Furusho H, Rider DB, Dobeck JM, Kuo WP, Fujimura A, Yoganathan S, Hirai K, Xu S, Sasaki K, Stashenko P.

J Endod. 2019 Feb;45(2):181-188. doi: 10.1016/j.joen.2018.10.007.


Interleukin 22 Expands Transit-Amplifying Cells While Depleting Lgr5+ Stem Cells via Inhibition of Wnt and Notch Signaling.

Zha JM, Li HS, Lin Q, Kuo WT, Jiang ZH, Tsai PY, Ding N, Wu J, Xu SF, Wang YT, Pan J, Zhou XM, Chen K, Tao M, Odenwald MA, Tamura A, Tsukita S, Turner JR, He WQ.

Cell Mol Gastroenterol Hepatol. 2019;7(2):255-274. doi: 10.1016/j.jcmgh.2018.09.006. Epub 2018 Sep 18.


The changes of quality of life and their correlations with psychosocial factors following surgery among women with breast cancer from the post-surgery to post-treatment survivorship.

Hsiao FH, Kuo WH, Jow GM, Wang MY, Chang KJ, Lai YM, Chen YT, Huang CS.

Breast. 2019 Apr;44:59-65. doi: 10.1016/j.breast.2018.12.011. Epub 2019 Jan 4.


Extending the Lifespan of Soluble Lead Flow Batteries with a Sodium Acetate Additive.

Lin YT, Kuo WC, Lee CY, Tan HL, Chen HY, Chan HW, Lai YH, Pan KR.

J Vis Exp. 2019 Jan 7;(143). doi: 10.3791/58484.


ROS- and HIF1α-dependent IGFBP3 upregulation blocks IGF1 survival signaling and thereby mediates high-glucose-induced cardiomyocyte apoptosis.

Huang YT, Liu CH, Yang YC, Aneja R, Wen SY, Huang CY, Kuo WW.

J Cell Physiol. 2019 Aug;234(8):13557-13570. doi: 10.1002/jcp.28034. Epub 2019 Jan 19.


Prophylactic IVC filter placement in bariatric surgery patients: results from a prospective filter registry.

Sheu AY, Hoang NS, Kesselman AJ, Liang T, Rosenberg JK, Kuo WT.

CVIR Endovasc. 2018;1(1):13. doi: 10.1186/s42155-018-0021-5. Epub 2018 Nov 15.


Effect of length of time from diagnosis to treatment on colorectal cancer survival: A population-based study.

Lee YH, Kung PT, Wang YH, Kuo WY, Kao SL, Tsai WC.

PLoS One. 2019 Jan 14;14(1):e0210465. doi: 10.1371/journal.pone.0210465. eCollection 2019.


Breast tumor classification using different features of quantitative ultrasound parametric images.

Hsu SM, Kuo WH, Kuo FC, Liao YY.

Int J Comput Assist Radiol Surg. 2019 Apr;14(4):623-633. doi: 10.1007/s11548-018-01908-8. Epub 2019 Jan 8.


Biodistribution, pharmacokinetics and radioimmunotherapy of 188Re-cetuximab in NCI-H292 human lung tumor-bearing nude mice.

Chang YJ, Ho CL, Cheng KH, Kuo WI, Lee WC, Lan KL, Chang CH.

Invest New Drugs. 2019 Jan 5. doi: 10.1007/s10637-018-00718-8. [Epub ahead of print]


Waxy allele diversification in foxtail millet (Setaria italica) landraces of Taiwan.

Kuo SM, Chen YR, Yin SY, Ba QX, Tsai YC, Kuo WHJ, Lin YR.

PLoS One. 2018 Dec 31;13(12):e0210025. doi: 10.1371/journal.pone.0210025. eCollection 2018.


Radiolabeling, Characteristics and NanoSPECT/CT Imaging of 188Re-cetuximab in NCI-H292 Human Lung Cancer Xenografts.

Kuo WI, Cheng KH, Chang YJ, Wu TT, Hsu WC, Chen LC, Chang CH.

Anticancer Res. 2019 Jan;39(1):183-190. doi: 10.21873/anticanres.13096.


Exercise training augments Sirt1-signaling and attenuates cardiac inflammation in D-galactose induced-aging rats.

Chen WK, Tsai YL, Shibu MA, Shen CY, Chang-Lee SN, Chen RJ, Yao CH, Ban B, Kuo WW, Huang CY.

Aging (Albany NY). 2018 Dec 23;10(12):4166-4174. doi: 10.18632/aging.101714.


CXCL2/CXCR2 axis induces cancer stem cell characteristics in CPT-11-resistant LoVo colon cancer cells via Gαi-2 and Gαq/11.

Chen MC, Baskaran R, Lee NH, Hsu HH, Ho TJ, Tu CC, Lin YM, Viswanadha VP, Kuo WW, Huang CY.

J Cell Physiol. 2019 Jul;234(7):11822-11834. doi: 10.1002/jcp.27891. Epub 2018 Dec 14.


Energy conversion from environmental fluctuations to coherent fields by Cooper-pair box quantum meta-materials.

Ho IL, Kuo W.

J Phys Condens Matter. 2019 Feb 6;31(5):055702. doi: 10.1088/1361-648X/aaf1f9. Epub 2018 Nov 19.


Alterations of Renal Epithelial Glucose and Uric Acid Transporters in Fructose Induced Metabolic Syndrome.

Ng HY, Lee YT, Kuo WH, Huang PC, Lee WC, Lee CT.

Kidney Blood Press Res. 2018;43(6):1822-1831. doi: 10.1159/000495814. Epub 2018 Dec 7.


Effective binding to protein antigens by antibodies from antibody libraries designed with enhanced protein recognition propensities.

Jian JW, Chen HS, Chiu YK, Peng HP, Tung CP, Chen IC, Yu CM, Tsou YL, Kuo WY, Hsu HJ, Yang AS.

MAbs. 2019 Feb/Mar;11(2):373-387. doi: 10.1080/19420862.2018.1550320. Epub 2019 Jan 9.


Generation of renal Epo-producing cell lines by conditional gene tagging reveals rapid HIF-2 driven Epo kinetics, cell autonomous feedback regulation, and a telocyte phenotype.

Imeri F, Nolan KA, Bapst AM, Santambrogio S, Abreu-Rodríguez I, Spielmann P, Pfundstein S, Libertini S, Crowther L, Orlando IMC, Dahl SL, Keodara A, Kuo W, Kurtcuoglu V, Scholz CC, Qi W, Hummler E, Hoogewijs D, Wenger RH.

Kidney Int. 2019 Feb;95(2):375-387. doi: 10.1016/j.kint.2018.08.043. Epub 2018 Nov 27.


The Number of Comorbidities Predicts Renal Outcomes in Patients with Stage 3⁻5 Chronic Kidney Disease.

Lee WC, Lee YT, Li LC, Ng HY, Kuo WH, Lin PT, Liao YC, Chiou TT, Lee CT.

J Clin Med. 2018 Nov 28;7(12). pii: E493. doi: 10.3390/jcm7120493.


Overexpression of IGF-IIRα regulates cardiac remodeling and aggravates high salt induced apoptosis and fibrosis in transgenic rats.

Chang RL, Nithiyanantham S, Kuo WW, Pai PY, Chang TT, Lai CH, Chen RJ, Vijaya Padma V, Huang CY, Huang CY.

Environ Toxicol. 2019 Feb;34(2):210-218. doi: 10.1002/tox.22676. Epub 2018 Nov 18.


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