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Items: 18


Xanthohumol increases death receptor 5 expression and enhances apoptosis with the TNF-related apoptosis-inducing ligand in neuroblastoma cell lines.

Engelsgjerd S, Kunnimalaiyaan S, Kandil E, Gamblin TC, Kunnimalaiyaan M.

PLoS One. 2019 Mar 14;14(3):e0213776. doi: 10.1371/journal.pone.0213776. eCollection 2019.


Antiproliferative and apoptotic effect of LY2090314, a GSK-3 inhibitor, in neuroblastoma in vitro.

Kunnimalaiyaan S, Schwartz VK, Jackson IA, Clark Gamblin T, Kunnimalaiyaan M.

BMC Cancer. 2018 May 11;18(1):560. doi: 10.1186/s12885-018-4474-7.


Antiproliferative and apoptotic effects of xanthohumol in cholangiocarcinoma.

Walden D, Kunnimalaiyaan S, Sokolowski K, Clark TG, Kunnimalaiyaan M.

Oncotarget. 2017 Sep 30;8(50):88069-88078. doi: 10.18632/oncotarget.21422. eCollection 2017 Oct 20.


Suberoylanilide hydroxamic Acid, a histone deacetylase inhibitor, alters multiple signaling pathways in hepatocellular carcinoma cell lines.

Kunnimalaiyaan S, Sokolowski K, Gamblin TC, Kunnimalaiyaan M.

Am J Surg. 2017 Apr;213(4):645-651. doi: 10.1016/j.amjsurg.2016.12.001. Epub 2016 Dec 11.


Role of Akt inhibition on Notch1 expression in hepatocellular carcinoma: potential role for dual targeted therapy.

Sokolowski KM, Balamurugan M, Kunnimalaiyaan S, Wilson J, Gamblin TC, Kunnimalaiyaan M.

Am J Surg. 2016 Apr;211(4):755-60. doi: 10.1016/j.amjsurg.2015.11.029. Epub 2016 Jan 6.


Potential Molecular Targeted Therapeutics: Role of PI3-K/Akt/mTOR Inhibition in Cancer.

Sokolowski KM, Koprowski S, Kunnimalaiyaan S, Balamurugan M, Gamblin TC, Kunnimalaiyaan M.

Anticancer Agents Med Chem. 2016;16(1):29-37. Review.


Glycogen synthase kinase-3 inhibitor AR-A014418 suppresses pancreatic cancer cell growth via inhibition of GSK-3-mediated Notch1 expression.

Kunnimalaiyaan S, Gamblin TC, Kunnimalaiyaan M.

HPB (Oxford). 2015 Sep;17(9):770-6. doi: 10.1111/hpb.12442. Epub 2015 Jul 6.


Xanthohumol inhibits Notch signaling and induces apoptosis in hepatocellular carcinoma.

Kunnimalaiyaan S, Sokolowski KM, Balamurugan M, Gamblin TC, Kunnimalaiyaan M.

PLoS One. 2015 May 26;10(5):e0127464. doi: 10.1371/journal.pone.0127464. eCollection 2015.


Curcumin-mediated regulation of Notch1/hairy and enhancer of split-1/survivin: molecular targeting in cholangiocarcinoma.

Koprowski S, Sokolowski K, Kunnimalaiyaan S, Gamblin TC, Kunnimalaiyaan M.

J Surg Res. 2015 Oct;198(2):434-40. doi: 10.1016/j.jss.2015.03.029. Epub 2015 Mar 19. Review.


Xanthohumol-Mediated Suppression of Notch1 Signaling Is Associated with Antitumor Activity in Human Pancreatic Cancer Cells.

Kunnimalaiyaan S, Trevino J, Tsai S, Gamblin TC, Kunnimalaiyaan M.

Mol Cancer Ther. 2015 Jun;14(6):1395-403. doi: 10.1158/1535-7163.MCT-14-0915. Epub 2015 Apr 17.


Inhibition of the AKT pathway in cholangiocarcinoma by MK2206 reduces cellular viability via induction of apoptosis.

Wilson JM, Kunnimalaiyaan S, Kunnimalaiyaan M, Gamblin TC.

Cancer Cell Int. 2015 Feb 4;15(1):13. doi: 10.1186/s12935-015-0161-9. eCollection 2015.


MK2206 inhibits hepatocellular carcinoma cellular proliferation via induction of apoptosis and cell cycle arrest.

Wilson JM, Kunnimalaiyaan S, Gamblin TC, Kunnimalaiyaan M.

J Surg Res. 2014 Oct;191(2):280-5. doi: 10.1016/j.jss.2014.05.083. Epub 2014 Jun 4.


Specific glycogen synthase kinase-3 inhibition reduces neuroendocrine markers and suppresses neuroblastoma cell growth.

Carter YM, Kunnimalaiyaan S, Chen H, Gamblin TC, Kunnimalaiyaan M.

Cancer Biol Ther. 2014 May;15(5):510-5. doi: 10.4161/cbt.28015. Epub 2014 Feb 12.


Mitochondria-targeted antioxidant and glycolysis inhibition: synergistic therapy in hepatocellular carcinoma.

Dilip A, Cheng G, Joseph J, Kunnimalaiyaan S, Kalyanaraman B, Kunnimalaiyaan M, Gamblin TC.

Anticancer Drugs. 2013 Oct;24(9):881-8. doi: 10.1097/CAD.0b013e32836442c6.


Neuroendocrine phenotype alteration and growth suppression through apoptosis by MK-2206, an allosteric inhibitor of AKT, in carcinoid cell lines in vitro.

Somnay Y, Simon K, Harrison AD, Kunnimalaiyaan S, Chen H, Kunnimalaiyaan M.

Anticancer Drugs. 2013 Jan;24(1):66-72. doi: 10.1097/CAD.0b013e3283584f75. Erratum in: Anticancer Drugs. 2013 Jul;24(6):658.


Structure-based functional analysis of the replication protein of plasmid R6K: key amino acids at the pi/DNA interface.

Kunnimalaiyaan S, Rakowski SA, Filutowicz M.

J Bacteriol. 2007 Jul;189(13):4953-6. Epub 2007 Apr 20.


Role of pi dimers in coupling ("handcuffing") of plasmid R6K's gamma ori iterons.

Kunnimalaiyaan S, Inman RB, Rakowski SA, Filutowicz M.

J Bacteriol. 2005 Jun;187(11):3779-85.


Binding modes of the initiator and inhibitor forms of the replication protein pi to the gamma ori iteron of plasmid R6K.

Kunnimalaiyaan S, Kr├╝ger R, Ross W, Rakowski SA, Filutowicz M.

J Biol Chem. 2004 Sep 24;279(39):41058-66. Epub 2004 Jul 9.

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