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Items: 12


Tityus serrulatus Scorpion Venom: In Vitro Tests and Their Correlation with In Vivo Lethal Dose Assay.

Cajado-Carvalho D, Galvão J, Kuniyoshi AK, Carneiro PDS, Paes Leme AF, Pauletti BA, Marengo EB, Portaro FV.

Toxins (Basel). 2017 Nov 23;9(12). pii: E380. doi: 10.3390/toxins9120380.


In vitro cleavage of bioactive peptides by peptidases from Bothrops jararaca venom and its neutralization by bothropic antivenom produced by Butantan Institute: Major contribution of serine peptidases.

Kuniyoshi AK, Kodama RT, Moraes LHF, Duzzi B, Iwai LK, Lima IF, Cajado-Carvalho D, Portaro FV.

Toxicon. 2017 Oct;137:114-119. doi: 10.1016/j.toxicon.2017.07.020. Epub 2017 Jul 28.


Edema and Nociception Induced by Philodryas patagoniensis Venom in Mice: A Pharmacological Evaluation with Implications for the Accident Treatment.

Lopes PH, Rocha MMT, Kuniyoshi AK, Portaro FCV, Gonçalves LRC.

J Pharmacol Exp Ther. 2017 Jun;361(3):349-354. doi: 10.1124/jpet.116.239640. Epub 2017 Mar 27.


Insights into the Hypertensive Effects of Tityus serrulatus Scorpion Venom: Purification of an Angiotensin-Converting Enzyme-Like Peptidase.

Cajado-Carvalho D, Kuniyoshi AK, Duzzi B, Iwai LK, Oliveira ÚC, Junqueira de Azevedo IL, Kodama RT, Portaro FV.

Toxins (Basel). 2016 Nov 24;8(12). pii: E348.


Intrahippocampal injection of TsTX-I increases the levels of INF-γ in the cerebral tissue but not the levels of glutamate.

Rodriguez RV, Dorce VA, de Freitas LA, Dorce AL, Lebrun I, Sobral AC, Portaro FC, Kuniyoshi AK, Carvalho DC, Nencioni AL.

Toxicon. 2015 Sep;103:155-9. doi: 10.1016/j.toxicon.2015.07.006. Epub 2015 Jul 7.


[des-Arg(1)]-Proctolin: A novel NEP-like enzyme inhibitor identified in Tityus serrulatus venom.

Duzzi B, Cajado-Carvalho D, Kuniyoshi AK, Kodama RT, Gozzo FC, Fioramonte M, Tambourgi DV, Portaro FV, Rioli V.

Peptides. 2016 Jun;80:18-24. doi: 10.1016/j.peptides.2015.05.013. Epub 2015 Jun 6.


New proline-rich oligopeptides from the venom of African adders: Insights into the hypotensive effect of the venoms.

Kodama RT, Cajado-Carvalho D, Kuniyoshi AK, Kitano ES, Tashima AK, Barna BF, Takakura AC, Serrano SM, Dias-Da-Silva W, Tambourgi DV, Portaro FV.

Biochim Biophys Acta. 2015 Jun;1850(6):1180-7. doi: 10.1016/j.bbagen.2015.02.005. Epub 2015 Feb 14.


African adders: partial characterization of snake venoms from three Bitis species of medical importance and their neutralization by experimental equine antivenoms.

Paixão-Cavalcante D, Kuniyoshi AK, Portaro FC, da Silva WD, Tambourgi DV.

PLoS Negl Trop Dis. 2015 Feb 2;9(2):e0003419. doi: 10.1371/journal.pntd.0003419. eCollection 2015 Feb.


Neuropeptide Y family-degrading metallopeptidases in the Tityus serrulatus venom partially blocked by commercial antivenoms.

Cajado Carvalho D, Kuniyoshi AK, Kodama RT, Oliveira AK, Serrano SM, Tambourgi DV, Portaro FV.

Toxicol Sci. 2014 Dec;142(2):418-26. doi: 10.1093/toxsci/kfu193. Epub 2014 Sep 19.


Enzymatic properties of venoms from Brazilian scorpions of Tityus genus and the neutralisation potential of therapeutical antivenoms.

Venancio EJ, Portaro FC, Kuniyoshi AK, Carvalho DC, Pidde-Queiroz G, Tambourgi DV.

Toxicon. 2013 Jul;69:180-90. doi: 10.1016/j.toxicon.2013.02.012. Epub 2013 Mar 15.


Insights into scorpion venom peptides: alternative processing of β-KTx propeptide from Tityus serrulatus venom results in a new naturally occurring thimet oligopeptidase inhibitor.

Carvalho DC, Duzzi B, Kuniyoshi AK, Fioramonte M, Gozzo FC, Melo RL, Tambourgi DV, Rioli V, Portaro FC.

Peptides. 2013 Feb;40:30-3. doi: 10.1016/j.peptides.2012.11.019. Epub 2012 Dec 8.


Angiotensin-degrading serine peptidase: a new chymotrypsin-like activity in the venom of Bothrops jararaca partially blocked by the commercial antivenom.

Kuniyoshi AK, Rocha M, Cajado Carvalho D, Juliano MA, Juliano Neto L, Tambourgi DV, Portaro FC.

Toxicon. 2012 Jan;59(1):124-31. doi: 10.1016/j.toxicon.2011.11.001. Epub 2011 Nov 10.

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